Conventional Antipsychotic medications

Drug Name (Generic) Brand Name Indication Adverse Reaction

Haloperidol Serenace Psychotic disorder CNS: severe extra pyramidal reactions, dyskinesia,
seizures, lethargy
CV: hypotension, tachycardia
GI: anorexia, constipation, dry mouth
Chlorpromazine Laractyl Thorazine Psychotic Disorders CNS: severe extra pyramidal reactions, dyskinesia,
dizziness, drowsiness
CV: tachycardia
GI: nausea
constipation, dry mouth
Loxapine 1.Loxitane
2.Daxoline
Psychotic Disorders -very stiff (rigid) muscles, high fever, sweating, confusion
- fast or uneven heartbeats, feeling like you might pass
out
-restless muscle movements in your eyes, tongue, jaw, or
neck
-tremor (uncontrolled shaking);
-trouble swallowing
-seizure (convulsions)
-easy bruising or bleeding, unusual weakness
-fever, chills, body aches, flu symptoms;
-vision changes
-severe constipation
-problem urinating
Mesoridazine Serentil Psychotic Disorders Central Nervous System: Drowsiness, Parkinsons
syndrome, dizziness, weakness, tremor, restlessness,
ataxia, dystonia, rigidity, slurring, akathisia, motoric
reactions (opisthotonos) have been reported.
Autonomic Nervous System: Dry mouth, nausea and
vomiting, fainting, stuffy nose, photophobia, constipation
and blurred vision have occurred in some instances.
Genitourinary System: Inhibition of ejaculation,
impotence, enuresis, incontinence, and priapism have
been reported.
Skin: Itching, rash, hypertrophic papillae of the tongue
and angioneurotic edema have been reported.
Molindone Moban Psychotic Disorders dizziness or drowsiness;
depressed mood;
feeling restless or agitated;
blurred vision;
dry mouth;
breast swelling or discharge;
changes in your menstrual periods;
nausea, constipation; or
changes in weight.
Perphenazine Trilafone Psychotic Dsiorders -extrapyramidal side effects
-drooling, trouble swallowing, problems with balance or
walking
-feeling restless, jittery, or agitated;
confusion, unusual thoughts or behavior;
feeling like you might pass out
-seizure (convulsions)
-decreased night vision, tunnel vision, watery eyes,
increased sensitivity to light;
nausea and stomach pain, skin rash, and jaundice
(yellowing of the skin or eyes);
high fever, stiff muscles, confusion, sweating, fast or
uneven heartbeats, rapid breathing
pale skin, easy bruising or bleeding, fever, sore throat, flu
symptoms
-sexual dysfuntion

Pimozide Orap Psychotic Dsiorders -seizure (convulsions)
-twitching or uncontrollable movements of your eyes,
lips, tongue, face, arms, or legs
-very stiff (rigid) muscles, high fever, sweating, confusion,
fast or uneven heartbeats, tremors,
-constipation
drymouth
Sulpiride Dogmatil Psychotic Dsiorders -Neuroleptic Malignant Syndrome
(NMS) - symptoms include
sudden fever, fast breathing,
blood pressure changes, sweating,
confusion, muscle stiffness and
drowsiness or sleepiness
-Tardive Dyskinesia (TD) -
unusual movements (mainly of
the face and tongue), or
uncontrollable twitching or
jerking of the arms and legs
-Blood dyscrasias
Examples include:
Agranulocytosis, Neutropaenia,Leucopenia,Leukocytosis
-Seizures
-Torsades de Pointes
Thioridazine Melleril Psychotic Dsiorders headache with chest pain and severe dizziness, fainting,
fast or pounding heartbeats
slow heart rate, weak pulse, fainting, slow breathing;
very stiff (rigid) muscles, high fever, sweating, confusion,
fast or uneven heartbeats, feeling like you might pass out;
twitching or uncontrollable movements of your eyes, lips,
tongue, face, arms, or legs;
tremor (uncontrolled shaking), drooling, trouble
swallowing, problems with balance or walking
feeling restless, jittery, or agitated;
seizure (convulsions);
decreased night vision, tunnel vision watery eyes,
increased sensitivity to light;
pale skin, easy bruising or bleeding, fever, chills, flu
symptoms, sores in your mouth and throat
-jaundice
Thiotixine Navane Psychotic Dsiorders very stiff (rigid) muscles, high fever, sweating, confusion,
fast or uneven heartbeats, feeling like you might pass out;
twitching or uncontrollable movements of your eyes, lips,
tongue, face, arms, or legs;
tremor (uncontrolled shaking);
trouble swallowing;
vision changes;
swelling in your hands or feet;
seizure (convulsions);
pale skin, easy bruising or bleeding, unusual weakness; or
fever, chills, body aches, flu symptoms.
Triflouperazine Stelazine Psychotic Disorders twitching or uncontrollable movements of your eyes, lips,
tongue, face, arms, or legs;
tremor, drooling, trouble swallowing, problems with
balance or walking;
feeling restless, jittery, or agitated;
very stiff muscles, high fever, sweating, confusion, fast or
uneven heartbeats, feeling like you might pass out;
decreased night vision, tunnel vision, watery eyes,
increased sensitivity to light;
seizure (black-out or convulsions);
nausea and stomach pain, skin rash, and jaundice
(yellowing of the skin or eyes);
urinating less than usual or not at all;
pale skin, easy bruising or bleeding, fever, sore throat, flu
symptoms;
joint pain or swelling with fever, swollen glands, muscle
aches, chest pain, vomiting, unusual thoughts or
behavior, and patchy skin color; or
slow heart rate, weak pulse, fainting, slow breathing
(breathing may stop).
Fluphenazine Phlufdek Psychotic Disorders witching or uncontrollable movements of your eyes, lips,
tongue, face, arms, or legs;
tremor (uncontrolled shaking), drooling, trouble
swallowing, problems with balance or walking;
feeling like you might pass out;
seizure (convulsions);
blurred vision, eye pain, seeing halos around lights;
pale skin, easy bruising or bleeding, mouth sores, severe
tingling, numbness, pain, muscle weakness;
dark urine, clay-colored stools, jaundice (yellowing of the
skin or eyes);
very stiff (rigid) muscles, high fever, sweating, confusion,
fast or uneven heartbeats; or
slow heart rate, weak pulse, fainting, slow breathing
(breathing may stop).
-sexual dyfunction


Atypical antipsychotic medications
Drug Name (Generic) Brand
Name
Indication Adverse Reaction
Amisulpride Solian Psychotic Disorder; Schizophrenia -Extrapyramidal side effects (EPS; including dystonia,
tremor, akathisia, parkinsonism)
-Anticholinergic effect (constipation,dry mouth,disorder of
accommodation, Blurred vision)
-insomia
-nausea and vomiting
-hyperactivity
-hypersalivation
Clozapine Leponex Psychotic Disorder CNS: difficulty sleeping,seizures
CV: agranulocytosis
Anticholinergic effect (constipation,dry mouth,disorder of
accommodation, Blurred vision)
-dementia-related psychosis
-dizziness, orthostatic hypotension
-constipation
RIsperidone Risperdal Psychotic Disorder; antimania -fever, stiff muscles, confusion, sweating, fast or uneven
heartbeats;
-restless muscle movements in your eyes, tongue, jaw, or
neck
-drooling, tremor (uncontrolled shaking)
-seizure (convulsions)
-white patches or sores inside your mouth or on your lips;
-difficulty swallowing;
-sexual dysfunction
-headache, dizziness;
-drowsiness, tired feeling;
- increased appetite; weight gain
-feeling restless or anxious;
-sleep problems (insomnia);
-nausea, vomiting, stomach pain, constipation;
-cough, sore throat, runny or stuffy nose
Olanzapine Zyprexa Psychotic Disorder;manic-
depressive
-very stiff (rigid) muscles, high fever, tremors, sweating,
confusion, fast or uneven heartbeats, slow heart rate,
-twitching or uncontrollable movements of your eyes, lips,
tongue, face, arms, or legs;
-trouble speaking or swallowing;
-dry mouth, thirst, feeling very hot (with or without
sweating), urinating less than usual or not at all;
-high blood sugar (increased thirst, loss of appetite, fruity
breath odor, increased urination, drowsiness, dry skin,
nausea, and vomiting);
-sudden numbness or weakness, confusion, or problems
with vision, speech, or balance;
-fever, chills, body aches, flu symptoms, sores in your
mouth and throat;
swelling in your hands or feet;
-changes in personality, unusual thoughts or behavior,
hallucinations, or thoughts about hurting yourself
-upper stomach pain, itching, loss of appetite, dark urine,
clay-colored stools, jaundice (yellowing of the skin or
eyes).
Quetiapine Seroquel Psychotic Disorder; manic-
depressive
-a light-headed feeling, like you might pass out
-very stiff (rigid) muscles, high fever, sweating, confusion,
fast or uneven heartbeats, tremors
-twitching or uncontrollable movements of your eyes, lips,
tongue, face, arms, or legs
-mask-like appearance of the face, trouble swallowing,
problems with speech;
-breast swelling or discharge (in men or women), missed
menstrual periods, impotence, loss of libido
-blurred vision, tunnel vision, eye pain, or seeing halos
around lights
-sudden weakness or ill feeling, fever, chills, cold or flu
-symptoms, cough, sore throat, red or swollen gums,
painful mouth sores, skin sores, trouble breathing
Ziprasidone Zeldox Psychotic Disorder -Neuroleptic Malignant Syndrome
(NMS) - symptoms include
sudden fever, fast breathing,
blood pressure changes, sweating,
confusion, muscle stiffness and
drowsiness or sleepiness
-Tardive Dyskinesia (TD) -
unusual movements (mainly of
the face and tongue), or
uncontrollable twitching or
jerking of the arms and legs