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EDITORIAL
editorial
Luigi Anastasia
Being a Scientist
today: are you still
having fun?
Being a Scientist in the 21st century is a real challenge: too many things
are distracting us from our true goals. It feels like we are loosing the
excitement and fun that has driven us here. It is time to take a look to
the past to find a way to move forward in the right direction: there are still so
many crucial issues, especially in Medicine and Drug Discovery that only
genuine Scientists can solve.
It seems like only yesterday, but exactly ten years have passed
since I got my PhD in Organic Chemistry. I am sure that many of
you have had a similar experience, when it feels the right time to
take a moment and look back, to see how the Scientific World has
changed over the years, to better understand where we are and
where we should go next.
The first question I asked myself, which Id like you to answer as
well, is rather simple: are you still having fun in doing research?
Dont answer yet, please take a deep breath and look around
you. If you are a University Professor like me, you are probably
sitting in your office, in front of a computer, with fifty or more
emails lingering in your inbox waiting for an answer, one important grant proposal deadline getting closer and closer, a couple of
papers to review, at least one paper to send back for the third round
of revision (because five different experiments supporting your
hypothesis are still not enough for the referees), the thesis of one of
your PhD students that needs to be completely re-written,
and. . .oh, damn, I have to leave you, I almost forgot, in five
minutes I have my third meeting of the day, this time about
the totally unnecessary new Departmental reorganization. I will
be back.
Yes, this is our life today. Our lab coat is there in a corner,
hanging on the wall, white and clean. Well, not completely true, it
has some dust on it, but thats ok, it is still ready for the next
picture for an interview with some local newspaper, celebrating
our latest breakthrough discovery, if it ever happens again.
Am I totally wrong? Do you still have time to go back to your
beloved bench? Well, whether you like it or not, this is our life as a
Scientist in the 21st Century.
So, let me ask you again: are you still having fun? Dont answer yet,
lets take a closer look.
Being a researcher today has become a completely different job
compared with that of our mentors. Yes, probably the Internet has
made the biggest change, we all know that. We heavily depend on
it for our research, as much as we do in our lives. This revolution
has made dramatic changes in everything, in the way we work, the
way we communicate, the way we make new discoveries. But all
good things often come with drawbacks, and while we surely feel
that we can do more things in the same amount of time, we also
deeply feel that something is going really wrong in our lives, and
nobody seems to have time to try to fix it.
I was lucky enough to start my undergraduate degree in
chemistry when scientific journals where not online and we
had to take a class to learn how to use the Beilstein, the German
database of organic chemistry. Knowing only a few words in
German, searching for literature those days was a real nightmare,
not to talk about the endless evenings spent in the Chemistry
library, going up and down the iron stairs, searching for articles
and making photocopies. Today, we rarely visit our libraries, and
most of my students dont even know that we still have one in the
Department (do we still have one?). Today, with a couple of mouse
clicks, we can find and print any paper. Nice, isnt it? But here it
comes the strange thing: have you ever realized that, although it
takes only a few seconds to find all the published literature on a
1359-6446/06/$ - see front matter 2012 Elsevier Ltd. All rights reserved. http://dx.doi.org/10.1016/j.drudis.2012.10.001
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References
1 Shamoo, A.E. and Resnik, D.B. (2009) Responsible Conduct of Research. Oxford
University Press
2 Begley, C.G. and Ellis, L.M. (2012) Drug development: raise standards for preclinical
cancer research. Nature 483 (7391), 531533
3 Mullard, A. (2011) Reliability of new drug target claims called into question. Nat.
Rev. Drug Discov. 10 (9), 643644
4 Coolidge, H.J. and Lord, R.H. (1932) Archibald Cary Coolidge: Life and Letters. Books for
Libraries Press
Luigi Anastasia1,2
Department of Biomedical Sciences for Health,
Universita` degli Studi di Milano, via F.lli Cervi 93, 20090 Segrate (Milan), Italy
2
IRCCS Policlinico San Donato, San Donato Milanese, Italy
luigi.anastasia@unimi.it
www.drugdiscoverytoday.com
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