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Butylated hydroxyanisole
IUPAC name[hide]
2-tert-Butyl-4-hydroxyanisole and 3-tert-butyl-4hydroxyanisole (mixture)
Other names[hide]
BOA; tert-Butyl-4-hydroxyanisole; (1,1-Dimethylethyl)-4methoxyphenol; tert-Butyl-4-methoxyphenol; Antioxyne B [1]
Identifiers
25013-16-5 , 8003-24-5, 9009-68-1, 121-00CAS number
6, 88-32-4
PubChem
24667
ChemSpider 23068
UNII
REK4960K2U
ChEMBL
CHEMBL502074
Jmol-3D
Image 1
images
SMILES
[show]
InChI
[show]
Properties
Molecular
C11H16O2
formula
Molar mass
180.24 g mol1
Appearance
waxy solid
Density
1.0587 g/cm at 20 C
Melting point
Boiling point
Solubility in
water
Refractive
index (nD)
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Except where noted otherwise, data are given for materials in
their standard state (at 25 C, 100 kPa)
Infobox references
Contents
[hide]
1 Antioxidant properties
2 Controversy
3 See also
4 References
[edit] Controversy
Some controversy surrounds the use of BHA in foods. The US National Institutes of
Health report that BHA is reasonably anticipated to be a human carcinogen based on
evidence of carcinogenicity in experimental animals. In particular, when administered in
high doses as part of their diet, BHA causes papillomas and squamous cell carcinomas of
the forestomach in rats and Syrian golden hamsters.[5] In mice, there is no carcinogenic
effect,[5] and even evidence of a protective effect against the carcinogenicity of other
chemicals.[4]
When examining human population statistics, the usual low intake levels of BHA shows
no significant association with an increased risk of cancer.[6] The State of California, has,
however, listed it as a carcinogen.[7]
Anisole
Butylated hydroxytoluene (BHT)
[edit] References
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