Escolar Documentos
Profissional Documentos
Cultura Documentos
Project
[1]
Submitted By
Harshavardhan D. Gorakh
[2]
Table 1
Level
Factor
1
Apatit
e (a)
Factors
Factor Factor
2
3
pH (b)
abc
60 (+)
7 (+)
ab
60 (+)
7 (+)
ac
60 (+)
4 (-)
60 (+)
4 (-)
bc
30 (-)
7 (+)
30 (-)
7 (+)
30 (-)
4 (-)
(1)
30 (-)
4 (-)
Pb (c)
2.41
(+)
0.483
(-)
2.41
(+)
0.483
(-)
2.41
(+)
0.483
(-)
2.41
(+)
0.483
(-)
Table 2
FishBone
Pb milli Mole
Replica Replicat
te I
e II
1.82
1.81
0.01
0
1.11
1.04
0
0.01
2.11
2.18
0.03
0.05
1.7
1.69
0.05
0.05
FishBone
pH
Replica Replicat
te I
e II
5.22
5.12
6.84
6.61
3.35
3.34
5.77
6.25
5.29
5.06
5.93
6.02
3.39
3.34
4.5
4.74
Hydroxyapatite
Pb milli Mole
Replica Replicat
te I
e II
0.11
0.12
0
0
0.8
0.76
0.03
0.05
1.03
1.05
0
0
1.34
1.26
0.06
0.07
Hydroxyapatite
pH
Replica Replicat
te I
e II
3.49
3.46
5.84
5.9
2.7
2.74
3.36
3.24
3.22
3.22
5.53
5.43
2.82
2.79
3.28
3.28
FISHBONE Pb
General Linear Model: Fishbone Pb mM versus Apetite, pH, Pb
Factor
Apetite
pH
Pb
Type
fixed
fixed
fixed
Levels
2
2
2
Values
-1, 1
-1, 1
-1, 1
DF
1
1
1
1
1
1
1
8
15
Seq SS
0.2652
0.3481
10.9892
0.0225
0.1892
0.3600
0.0196
0.0053
12.1992
Adj SS
0.2652
0.3481
10.9892
0.0225
0.1892
0.3600
0.0196
0.0053
R-Sq = 99.96%
Adj MS
0.2652
0.3481
10.9892
0.0225
0.1892
0.3600
0.0196
0.0007
F
400.34
525.43
16587.51
33.96
285.62
543.40
29.58
P
0.000
0.000
0.000
0.000
0.000
0.000
0.001
R-Sq(adj) = 99.92%
Type
fixed
fixed
fixed
Levels
2
2
2
Values
-1, 1
-1, 1
-1, 1
DF
1
1
1
1
1
1
9
15
S = 0.0525991
Seq SS
0.2652
0.3481
10.9892
0.0225
0.1892
0.3600
0.0249
12.1992
Adj SS
0.2652
0.3481
10.9892
0.0225
0.1892
0.3600
0.0249
R-Sq = 99.80%
Adj MS
0.2652
0.3481
10.9892
0.0225
0.1892
0.3600
0.0028
F
95.86
125.82
3972.01
8.13
68.39
130.12
P
0.000
0.000
0.000
0.019
0.000
0.000
R-Sq(adj) = 99.66%
Type
fixed
fixed
fixed
Levels
2
2
2
Values
-1, 1
-1, 1
-1, 1
DF
1
1
1
1
1
10
15
Seq SS
0.2652
0.3481
10.9892
0.1892
0.3600
0.0474
12.1992
Adj SS
0.2652
0.3481
10.9892
0.1892
0.3600
0.0474
Adj MS
0.2652
0.3481
10.9892
0.1892
0.3600
0.0047
F
55.95
73.44
2318.40
39.92
75.95
P
0.000
0.000
0.000
0.000
0.000
S = 0.0688477
R-Sq = 99.61%
R-Sq(adj) = 99.42%
-1
-2
0.0
0.5
1.0
Fitted Value
1.5
2.0
Figure 1
Mean
StDev
N
AD
P-Value
95
90
80
Percent
Standardized Residual
70
60
50
40
30
20
10
5
-3
-2
-1
0
SRES1
Figure 2
6.485762E-15
1.033
16
0.865
0.020
Standardized Residual
1.0
0.5
0.0
-0.5
-1.0
-1.5
-2.0
0.0
0.5
1.0
1.5
Fitted Value
2.0
2.5
Figure 3
Mean
StDev
N
AD
P-Value
95
90
Percent
80
70
60
50
40
30
20
10
5
-3
-2
-1
0
SRES2
Figure 4
3.622103E-15
1.033
16
0.856
0.021
Type
fixed
fixed
fixed
Levels
2
2
2
Values
-1, 1
-1, 1
-1, 1
DF
1
1
1
1
1
10
15
S = 0.0688477
Seq SS
0.2652
0.3481
10.9892
0.1892
0.3600
0.0474
12.1992
Adj SS
0.2652
0.3481
10.9892
0.1892
0.3600
0.0474
R-Sq = 99.61%
Adj MS
0.2652
0.3481
10.9892
0.1892
0.3600
0.0047
F
55.95
73.44
2318.40
39.92
75.95
P
0.000
0.000
0.000
0.000
0.000
R-Sq(adj) = 99.42%
N
8
8
Mean
1.0
0.7
Grouping
A
B
Lower
-0.3342
Center
-0.2575
Upper
-0.1808
---+---------+---------+---------+--(------*-------)
---+---------+---------+---------+---0.30
-0.20
-0.10
-0.00
Apetite
1
SE of
Difference
0.03442
T-Value
-7.480
Adjusted
P-Value
0.0000
N
8
8
Mean
1.0
0.7
Grouping
A
B
Lower
0.2183
Center
0.2950
Upper
0.3717
------+---------+---------+---------+
(--------------*--------------)
------+---------+---------+---------+
0.250
0.300
0.350
0.400
Tukey Simultaneous Tests
Response Variable Fishbone Pb mM
All Pairwise Comparisons among Levels of pH
pH = -1 subtracted from:
pH
1
Difference
of Means
0.2950
SE of
Difference
0.03442
T-Value
8.570
Adjusted
P-Value
0.0000
N
8
8
Mean
1.7
0.0
Grouping
A
B
Lower
1.581
Center
1.658
Upper
1.734
----+---------+---------+---------+-(---------------*--------------)
----+---------+---------+---------+-1.600
1.650
1.700
1.750
Difference
of Means
1.658
SE of
Difference
0.03442
T-Value
48.15
Adjusted
P-Value
0.0000
Pb
1
1
-1
-1
N
4
4
4
4
Mean
1.9
1.4
0.0
0.0
Grouping
A
B
C
C
Pb
1
-1
1
Lower
1.7259
-0.1891
1.2509
Center
1.87500
-0.04000
1.40000
Upper
2.0241
0.1091
1.5491
-------+---------+---------+--------(-*)
(-*)
(-*)
-------+---------+---------+---------1.2
0.0
1.2
Apetite = -1
Pb = 1 subtracted from:
Apetite
1
1
Pb
-1
1
Lower
-2.064
-0.624
Center
-1.915
-0.475
Upper
-1.766
-0.326
-------+---------+---------+--------(*)
(*)
-------+---------+---------+---------1.2
0.0
1.2
Apetite = 1
Pb = -1 subtracted from:
Apetite
1
Pb
1
Lower
1.291
Center
1.440
Upper
1.589
-------+---------+---------+--------(*)
-------+---------+---------+---------1.2
0.0
1.2
Difference
of Means
1.87500
-0.04000
1.40000
Pb
1
-1
1
SE of
Difference
0.04868
0.04868
0.04868
T-Value
38.5148
-0.8216
28.7577
Adjusted
P-Value
0.0000
0.8430
0.0000
T-Value
-39.34
-9.76
Adjusted
P-Value
0.0000
0.0000
T-Value
29.58
Adjusted
P-Value
0.0000
Apetite = -1
Pb = 1 subtracted from:
Apetite
1
1
Difference
of Means
-1.915
-0.475
Pb
-1
1
SE of
Difference
0.04868
0.04868
Apetite = 1
Pb = -1 subtracted from:
Apetite
1
Difference
of Means
1.440
Pb
1
SE of
Difference
0.04868
Pb
1
1
-1
-1
N
4
4
4
4
Mean
2.0
1.4
0.0
0.0
Grouping
A
B
C
C
Pb
1
-1
1
Lower
1.2084
-0.1541
1.8034
Center
1.35750
-0.00500
1.95250
Upper
1.5066
0.1441
2.1016
-----+---------+---------+---------+(-*)
(-*)
(-*)
-----+---------+---------+---------+-1.0
0.0
1.0
2.0
pH = -1
Pb = 1
pH
1
1
Pb
-1
1
pH = 1
Pb = -1
pH
1
Pb
1
subtracted from:
Lower
-1.512
0.446
Center
-1.363
0.595
Upper
-1.213
0.744
-----+---------+---------+---------+(*-)
(-*)
-----+---------+---------+---------+-1.0
0.0
1.0
2.0
subtracted from:
Lower
1.808
Center
1.958
Upper
2.107
-----+---------+---------+---------+(-*)
-----+---------+---------+---------+-1.0
0.0
1.0
2.0
Pb
1
-1
1
pH = -1
Pb = 1
pH
1
1
Pb
-1
1
pH = 1
Pb = -1
pH
1
Pb
1
Difference
of Means
1.35750
-0.00500
1.95250
SE of
Difference
0.04868
0.04868
0.04868
T-Value
27.8847
-0.1027
40.1067
Adjusted
P-Value
0.0000
0.9996
0.0000
T-Value
-27.99
12.22
Adjusted
P-Value
0.0000
0.0000
T-Value
40.21
Adjusted
P-Value
0.0000
subtracted from:
Difference
of Means
-1.363
0.595
SE of
Difference
0.04868
0.04868
subtracted from:
Difference
of Means
1.958
SE of
Difference
0.04868
Standardized Residual
1.0
0.5
0.0
-0.5
-1.0
-1.5
-2.0
0.0
0.5
1.0
1.5
Fitted Value
2.0
2.5
Figure 5
Mean
StDev
N
AD
P-Value
95
90
Percent
80
70
60
50
40
30
20
10
5
-3
-2
-1
0
SRES3
Figure 6
2.080801E-15
1.033
16
0.699
0.055
Apetite
-1
1
A petite
pH
pH
-1
1
Pb
-1
1
Pb
0
-1
-1
Figure 7
FISHBONE pH
General Linear Model: Fishbone pH versus Apetite, pH, Pb
Factor
Apetite
pH
Pb
Type
fixed
fixed
fixed
Levels
2
2
2
Values
-1, 1
-1, 1
-1, 1
DF
1
1
1
1
1
1
1
8
15
Seq SS
1.1183
8.1368
9.8439
0.0977
1.1718
0.6123
0.1073
0.2073
21.2952
S = 0.160954
R-Sq = 99.03%
Adj SS
1.1183
8.1368
9.8439
0.0977
1.1718
0.6123
0.1073
0.2073
Adj MS
1.1183
8.1368
9.8439
0.0977
1.1718
0.6123
0.1073
0.0259
F
43.17
314.08
379.98
3.77
45.23
23.64
4.14
P
0.000
0.000
0.000
0.088
0.000
0.001
0.076
R-Sq(adj) = 98.18%
Versus Fits
(response is Fishbone pH)
Standardized Residual
-1
-2
3
5
Fitted Value
Figure 8
Mean
StDev
N
AD
P-Value
95
90
Percent
80
70
60
50
40
30
20
10
5
-3
-2
-1
0
SRES5
Figure 9
Type
fixed
fixed
fixed
Levels
2
2
2
Values
-1, 1
-1, 1
-1, 1
DF
1
1
1
1
1
10
15
Seq SS
1.1183
8.1368
9.8439
1.1718
0.6123
0.4122
21.2952
Adj SS
1.1183
8.1368
9.8439
1.1718
0.6123
0.4122
R-Sq = 98.06%
Adj MS
1.1183
8.1368
9.8439
1.1718
0.6123
0.0412
F
27.13
197.42
238.84
28.43
14.86
P
0.000
0.000
0.000
0.000
0.003
R-Sq(adj) = 97.10%
Fishbone pH
6.25000
Fit
5.85000
SE Fit
0.12432
Residual
0.40000
St Resid
2.49 R
N
8
8
Mean
5.3
4.8
Grouping
A
B
4.718448E-16
1.033
16
0.196
0.868
Lower
0.3026
Center
0.5287
Upper
0.7549
+---------+---------+---------+-----(--------------*--------------)
+---------+---------+---------+-----0.30
0.45
0.60
0.75
Apetite
1
SE of
Difference
0.1015
T-Value
5.209
Adjusted
P-Value
0.0004
N
8
8
Mean
5.8
4.3
Grouping
A
B
Lower
1.200
Center
1.426
Upper
1.652
+---------+---------+---------+-----(--------------*--------------)
+---------+---------+---------+-----1.20
1.35
1.50
1.65
Difference
of Means
1.426
SE of
Difference
0.1015
T-Value
14.05
Adjusted
P-Value
0.0000
N
8
8
Mean
5.8
4.3
Grouping
A
B
Lower
-1.795
Center
-1.569
Upper
-1.343
------+---------+---------+---------+
(----*---)
------+---------+---------+---------+
-1.50
-1.00
-0.50
0.00
Difference
of Means
-1.569
SE of
Difference
0.1015
T-Value
-15.45
Adjusted
P-Value
0.0000
Pb
-1
-1
1
1
N
4
4
4
4
Mean
6.4
5.3
4.3
4.3
Grouping
A
B
C
C
Pb
1
-1
1
Lower
-1.467
0.630
-1.480
Center
-1.028
1.070
-1.040
Upper
-0.5880
1.5095
-0.6005
-------+---------+---------+--------(--*--)
(--*--)
(--*--)
-------+---------+---------+---------1.5
0.0
1.5
Apetite = -1
Pb = 1 subtracted from:
Apetite
1
1
Pb
-1
1
Lower
1.6580
-0.4520
Center
2.09750
-0.01250
Upper
2.5370
0.4270
-------+---------+---------+--------(--*--)
(--*--)
-------+---------+---------+---------1.5
0.0
1.5
Apetite = 1
Pb = -1 subtracted from:
Apetite
1
Pb
1
Lower
-2.550
Center
-2.110
Upper
-1.670
-------+---------+---------+--------(--*--)
-------+---------+---------+---------1.5
0.0
1.5
Pb
1
-1
1
Difference
of Means
-1.028
1.070
-1.040
SE of
Difference
0.1436
0.1436
0.1436
T-Value
-7.158
7.454
-7.245
Adjusted
P-Value
0.0002
0.0001
0.0001
Apetite = -1
Pb = 1 subtracted from:
Apetite
1
1
Difference
of Means
2.09750
-0.01250
Pb
-1
1
SE of
Difference
0.1436
0.1436
T-Value
14.6111
-0.0871
Adjusted
P-Value
0.0000
0.9997
T-Value
-14.70
Adjusted
P-Value
0.0000
Apetite = 1
Pb = -1 subtracted from:
Apetite
1
Difference
of Means
-2.110
Pb
1
SE of
Difference
0.1436
Pb
-1
-1
1
1
N
4
4
4
4
Mean
6.3
5.3
5.2
3.4
Grouping
A
B
B
C
Pb
1
-1
1
pH = -1
Pb = 1
pH
1
1
Pb
-1
1
pH = 1
Pb = -1
pH
1
Pb
1
Lower
-2.400
0.595
-0.582
Center
-1.960
1.035
-0.143
Upper
-1.520
1.475
0.297
-----+---------+---------+---------+(--*-)
(-*--)
(--*--)
-----+---------+---------+---------+-1.6
0.0
1.6
3.2
subtracted from:
Lower
2.555
1.378
Center
2.995
1.817
Upper
3.435
2.257
-----+---------+---------+---------+(--*-)
(-*--)
-----+---------+---------+---------+-1.6
0.0
1.6
3.2
subtracted from:
Lower
-1.617
Center
-1.178
Upper
-0.7380
-----+---------+---------+---------+(--*-)
-----+---------+---------+---------+-1.6
0.0
1.6
3.2
Pb
1
Difference
of Means
-1.960
SE of
Difference
0.1436
T-Value
-13.65
Adjusted
P-Value
0.0000
-1
1
pH = -1
Pb = 1
pH
1
1
Pb
-1
1
pH = 1
Pb = -1
pH
1
Pb
1
1.035
-0.143
0.1436
0.1436
7.21
-0.99
0.0001
0.7569
T-Value
20.86
12.66
Adjusted
P-Value
0.0000
0.0000
T-Value
-8.202
Adjusted
P-Value
0.0001
subtracted from:
Difference
of Means
2.995
1.817
SE of
Difference
0.1436
0.1436
subtracted from:
Difference
of Means
-1.178
SE of
Difference
0.1436
Standardized Residual
1
1
-1
-2
3
5
Fitted Value
Figure 10
Mean
StDev
N
AD
P-Value
95
90
3.382711E-16
1.033
16
0.449
0.241
Percent
80
70
60
50
40
30
20
10
5
-3
-2
-1
0
SRES6
Figure 11
Apetite
-1
1
6
5
A petite
6
5
pH
pH
-1
1
Pb
-1
1
6
5
Pb
-1
-1
Figure 12
Hydroxyapatite Pb
General Linear Model: Hydroxyapatite Pb mM versus Apetite, pH, Pb
Factor
Apetite
pH
Pb
Type
fixed
fixed
fixed
Levels
2
2
2
Values
-1, 1
-1, 1
-1, 1
DF
1
1
1
1
1
1
1
8
15
Seq SS
0.54023
0.26523
2.44923
0.03610
0.50410
0.16810
0.04623
0.00450
4.01370
Adj SS
0.54022
0.26522
2.44923
0.03610
0.50410
0.16810
0.04623
0.00450
R-Sq = 99.89%
Adj MS
0.54022
0.26522
2.44923
0.03610
0.50410
0.16810
0.04623
0.00056
F
960.40
471.51
4354.18
64.18
896.18
298.84
82.18
P
0.000
0.000
0.000
0.000
0.000
0.000
0.000
R-Sq(adj) = 99.79%
Mean
StDev
N
AD
P-Value
95
90
Percent
80
70
60
50
40
30
20
10
5
-3
-2
-1
0
SRES7
Figure 13
7.542578E-15
1.033
16
0.534
0.145
Standardized Residual
2
1
0
-1
-2
-3
0.0
0.2
0.4
0.6
0.8
Fitted Value
1.0
1.2
Figure 14
Type
fixed
fixed
fixed
Levels
2
2
2
Values
-1, 1
-1, 1
-1, 1
DF
1
1
1
1
1
10
15
S = 0.0931799
Seq SS
0.54023
0.26523
2.44923
0.50410
0.16810
0.08683
4.01370
Adj SS
0.54022
0.26522
2.44923
0.50410
0.16810
0.08683
R-Sq = 97.84%
Adj MS
0.54022
0.26522
2.44923
0.50410
0.16810
0.00868
F
62.22
30.55
282.09
58.06
19.36
P
0.000
0.000
0.000
0.000
0.001
R-Sq(adj) = 96.76%
N
8
8
Mean
0.6
0.2
Grouping
A
B
Lower
-0.4713
Center
-0.3675
Upper
-0.2637
-+---------+---------+---------+----(------*-----)
-+---------+---------+---------+-----
1.4
-0.45
-0.30
-0.15
0.00
Apetite
1
SE of
Difference
0.04659
T-Value
-7.888
Adjusted
P-Value
0.0000
N
8
8
Mean
0.5
0.3
Grouping
A
B
Lower
-0.3613
Center
-0.2575
Upper
-0.1537
------+---------+---------+---------+
(---------*----------)
------+---------+---------+---------+
-0.30
-0.20
-0.10
-0.00
Difference
of Means
-0.2575
SE of
Difference
0.04659
T-Value
-5.527
Adjusted
P-Value
0.0003
N
8
8
Mean
0.8
0.0
Grouping
A
B
Lower
0.6787
Center
0.7825
Upper
0.8863
-------+---------+---------+--------(----------------*-----------------)
-------+---------+---------+--------0.720
0.780
0.840
Pb
1
Difference
of Means
0.7825
SE of
Difference
0.04659
T-Value
16.80
Adjusted
P-Value
0.0000
Pb
1
1
-1
-1
N
4
4
4
4
Mean
1.2
0.4
0.0
0.0
Grouping
A
B
C
C
Pb
1
-1
1
Lower
0.9358
-0.2142
0.2133
Center
1.13750
-0.01250
0.41500
Upper
1.3392
0.1892
0.6167
-------+---------+---------+--------(-*--)
(--*-)
(-*--)
-------+---------+---------+---------0.80
0.00
0.80
Apetite = -1
Pb = 1 subtracted from:
Apetite
1
1
Pb
-1
1
Lower
-1.352
-0.924
Center
-1.150
-0.723
Upper
-0.9483
-0.5208
-------+---------+---------+--------(--*-)
(--*-)
-------+---------+---------+---------0.80
0.00
0.80
Apetite = 1
Pb = -1 subtracted from:
Apetite
1
Pb
1
Lower
0.2258
Center
0.4275
Upper
0.6292
-------+---------+---------+--------(-*--)
-------+---------+---------+---------0.80
0.00
0.80
Pb
1
-1
1
Difference
of Means
1.13750
-0.01250
0.41500
SE of
Difference
0.06589
0.06589
0.06589
T-Value
17.2641
-0.1897
6.2986
Adjusted
P-Value
0.0000
0.9974
0.0004
T-Value
-17.45
-10.97
Adjusted
P-Value
0.0000
0.0000
Apetite = -1
Pb = 1 subtracted from:
Apetite
1
1
Pb
-1
1
Difference
of Means
-1.150
-0.723
SE of
Difference
0.06589
0.06589
Apetite = 1
Pb = -1 subtracted from:
Apetite
1
Difference
of Means
0.4275
Pb
1
SE of
Difference
0.06589
Adjusted
P-Value
0.0003
T-Value
6.488
Pb
1
1
-1
-1
N
4
4
4
4
Mean
1.0
0.6
0.1
-0.0
Grouping
A
B
C
C
Pb
1
-1
1
pH = -1
Pb = 1
pH
1
1
Pb
-1
1
pH = 1
Pb = -1
pH
1
Pb
1
Lower
0.7858
-0.2542
0.3233
Center
0.98750
-0.05250
0.52500
Upper
1.1892
0.1492
0.7267
--------+---------+---------+-------(--*--)
(--*--)
(--*-)
--------+---------+---------+--------0.70
0.00
0.70
subtracted from:
Lower
-1.242
-0.664
Center
-1.040
-0.463
Upper
-0.8383
-0.2608
--------+---------+---------+-------(--*--)
(-*--)
--------+---------+---------+--------0.70
0.00
0.70
subtracted from:
Lower
0.3758
Center
0.5775
Upper
0.7792
--------+---------+---------+-------(--*--)
--------+---------+---------+--------0.70
0.00
0.70
Pb
-1
1
pH = 1
Pb = -1
pH
Pb
Difference
of Means
0.98750
-0.05250
0.52500
SE of
Difference
0.06589
0.06589
0.06589
T-Value
14.9875
-0.7968
7.9680
Adjusted
P-Value
0.0000
0.8544
0.0001
subtracted from:
Difference
SE of
of Means Difference
-1.040
0.06589
-0.463
0.06589
T-Value
-15.78
-7.02
Adjusted
P-Value
0.0000
0.0002
T-Value
Adjusted
P-Value
subtracted from:
Difference
of Means
SE of
Difference
0.5775
0.06589
8.765
0.0000
Mean
StDev
N
AD
P-Value
95
90
1.837072E-15
1.033
16
0.507
0.171
80
Percent
70
60
50
40
30
20
10
5
-3
-2
-1
0
SRES12
Figure 15
Hydroxyapatite Pb interaction
-1
Apetite
-1
1
1.0
A petite
0.5
0.0
1.0
pH
pH
-1
1
0.5
0.0
Pb
-1
1
1.0
Pb
0.5
0.0
-1
-1
Figure 16
Hydroxyapatite pH
General Linear Model: Hydroxyapatite pH versus Apatite, pH, Pb
Factor
Apetite
pH
Pb
Type
fixed
fixed
fixed
Levels
2
2
2
Values
-1, 1
-1, 1
-1, 1
DF
1
1
1
1
1
1
1
8
15
Seq SS
0.0841
8.8209
8.1510
0.1260
0.0144
3.2400
0.0002
0.0157
20.4524
Adj SS
0.0841
8.8209
8.1510
0.1260
0.0144
3.2400
0.0002
0.0157
R-Sq = 99.92%
Adj MS
0.0841
8.8209
8.1510
0.1260
0.0144
3.2400
0.0002
0.0020
F
42.85
4494.73
4153.39
64.22
7.34
1650.96
0.11
P
0.000
0.000
0.000
0.000
0.027
0.000
0.744
R-Sq(adj) = 99.86%
Standardized Residual
-1
-2
3.0
3.5
4.0
4.5
Fitted Value
Figure 17
5.0
5.5
6.0
Mean
StDev
N
AD
P-Value
95
90
Percent
80
70
60
50
40
30
20
10
5
-3
-2
-1
0
SRES13
Figure 18
Type
fixed
fixed
fixed
Levels
2
2
2
Values
-1, 1
-1, 1
-1, 1
DF
1
1
1
1
1
1
9
15
S = 0.0420648
Seq SS
0.0841
8.8209
8.1510
0.1260
0.0144
3.2400
0.0159
20.4524
Adj SS
0.0841
8.8209
8.1510
0.1260
0.0144
3.2400
0.0159
R-Sq = 99.92%
Adj MS
0.0841
8.8209
8.1510
0.1260
0.0144
3.2400
0.0018
F
47.53
4985.12
4606.54
71.22
8.14
1831.08
R-Sq(adj) = 99.87%
P
0.000
0.000
0.000
0.000
0.019
0.000
-7.10656E-15
1.033
16
0.215
0.815
Standardized Residual
-1
-2
3.0
3.5
4.0
4.5
Fitted Value
5.0
5.5
6.0
Figure 19
Mean
StDev
N
AD
P-Value
95
90
Percent
80
70
60
50
40
30
20
10
5
-3
-2
-1
0
SRES14
Figure 20
-7.05165E-15
1.033
16
0.287
0.575
Type
fixed
fixed
fixed
Levels
2
2
2
Values
-1, 1
-1, 1
-1, 1
DF
1
1
1
1
1
10
15
Seq SS
0.0841
8.8209
8.1510
0.1260
3.2400
0.0303
20.4524
S = 0.0550681
Adj SS
0.0841
8.8209
8.1510
0.1260
3.2400
0.0303
R-Sq = 99.85%
Adj MS
0.0841
8.8209
8.1510
0.1260
3.2400
0.0030
F
27.73
2908.79
2687.89
41.56
1068.43
P
0.000
0.000
0.000
0.000
0.000
R-Sq(adj) = 99.78%
N
8
8
Mean
3.841
3.696
Grouping
A
B
Lower
0.08365
Center
0.1450
Upper
0.2063
------+---------+---------+---------+
(----------------*-----------------)
------+---------+---------+---------+
0.105
0.140
0.175
0.210
Apetite
1
SE of
Difference
0.02753
T-Value
5.266
Adjusted
P-Value
0.0004
N
8
8
Mean
4.511
3.026
Grouping
A
B
Lower
1.424
Center
1.485
Upper
1.546
---+---------+---------+---------+--(----------------*-----------------)
---+---------+---------+---------+--1.435
1.470
1.505
1.540
Tukey Simultaneous Tests
Response Variable Hydroxyapatite pH
All Pairwise Comparisons among Levels of pH
pH = -1 subtracted from:
pH
1
Difference
of Means
1.485
SE of
Difference
0.02753
T-Value
53.93
Adjusted
P-Value
0.0000
N
8
8
Mean
4.483
3.055
Grouping
A
B
Lower
-1.489
Center
-1.428
Upper
-1.366
+---------+---------+---------+-----(*-)
+---------+---------+---------+------1.50
-1.00
-0.50
0.00
Difference
of Means
-1.428
SE of
Difference
0.02753
T-Value
-51.84
Adjusted
P-Value
0.0000
pH
1
1
-1
-1
N
4
4
4
4
Mean
4.673
4.350
3.043
3.010
Grouping
A
B
C
C
pH
1
-1
1
Apetite = -1
Lower
1.1883
-0.1517
1.5108
Center
1.30750
-0.03250
1.63000
Upper
1.42672
0.08672
1.74922
-----+---------+---------+---------+(*)
(-*)
(*)
-----+---------+---------+---------+-1.0
0.0
1.0
2.0
pH =
subtracted from:
Apetite
1
1
pH
-1
1
Lower
-1.459
0.203
Center
-1.340
0.323
Upper
-1.221
0.442
-----+---------+---------+---------+(-*)
(*)
-----+---------+---------+---------+-1.0
0.0
1.0
2.0
Apetite = 1
pH = -1 subtracted from:
Apetite
1
pH
1
Lower
1.543
Center
1.662
Upper
1.782
-----+---------+---------+---------+(-*)
-----+---------+---------+---------+-1.0
0.0
1.0
2.0
Difference
of Means
1.30750
-0.03250
1.63000
pH
1
-1
1
SE of
Difference
0.03894
0.03894
0.03894
T-Value
33.5781
-0.8346
41.8603
Adjusted
P-Value
0.0000
0.8370
0.0000
T-Value
-34.41
8.28
Adjusted
P-Value
0.0000
0.0001
T-Value
42.69
Adjusted
P-Value
0.0000
Apetite = -1
pH = 1 subtracted from:
Apetite
1
1
Difference
of Means
-1.340
0.323
pH
-1
1
SE of
Difference
0.03894
0.03894
Apetite = 1
pH = -1 subtracted from:
Apetite
1
Difference
of Means
1.662
pH
1
SE of
Difference
0.03894
Pb
-1
1
-1
1
N
4
4
4
4
Mean
5.675
3.348
3.290
2.763
Grouping
A
B
B
C
Pb
1
-1
1
Lower
-0.6467
2.2658
-0.0617
Center
-0.5275
2.3850
0.0575
Upper
-0.4083
2.5042
0.1767
------+---------+---------+---------+
*)
(*)
*)
------+---------+---------+---------+
-1.5
pH = -1
Pb = 1
pH
1
1
Pb
-1
1
pH = 1
Pb = -1
pH
1
Pb
1
0.0
Pb
1
-1
1
pH = -1
Pb = 1
pH
1
1
Pb
-1
1
pH = 1
Pb = -1
pH
1
Pb
1
3.0
subtracted from:
Lower
2.7933
0.4658
Center
2.9125
0.5850
Upper
3.0317
0.7042
------+---------+---------+---------+
*)
(*)
------+---------+---------+---------+
-1.5
0.0
1.5
3.0
subtracted from:
Lower
-2.447
Center
-2.328
Upper
-2.208
------+---------+---------+---------+
*)
------+---------+---------+---------+
-1.5
0.0
1.5
3.0
1.5
Difference
of Means
-0.5275
2.3850
0.0575
SE of
Difference
0.03894
0.03894
0.03894
T-Value
-13.55
61.25
1.48
Adjusted
P-Value
0.0000
0.0000
0.4849
T-Value
74.80
15.02
Adjusted
P-Value
0.0000
0.0000
T-Value
-59.77
Adjusted
P-Value
0.0000
subtracted from:
Difference
of Means
2.9125
0.5850
SE of
Difference
0.03894
0.03894
subtracted from:
Difference
of Means
-2.328
SE of
Difference
0.03894
Standardized Residual
-1
-2
3.0
3.5
4.0
4.5
Fitted Value
5.0
5.5
6.0
Figure 21
Mean
StDev
N
AD
P-Value
95
90
Percent
80
70
60
50
40
30
20
10
5
-3
-2
-1
0
SRES4
Figure 22
-7.68829E-15
1.033
16
0.139
0.966
Apetite
-1
1
5
A petite
4
3
5
pH
pH
-1
1
4
3
Pb
-1
1
5
Pb
4
3
-1
-1
Figure 23
pH
Pb
-1
-1
-1
Bartlett's Test
Test Statistic
P-Value
1
1
7.13
0.309
-1
1
-1
-1
1
-1
1
0
2
4
6
8
10
12
95% Bonferroni Confidence Intervals for StDevs
Figure 24
Test for equal variance for Fishbone pH P- value 0.324 implies rejecting alternative hypothesis in
favor of null hypothesis
Test for Equal Variances for Fishbone pH
Apetite
pH
Pb
-1
-1
-1
Bartlett's Test
Test Statistic
P-Value
1
1
-1
1
-1
-1
1
-1
1
0
10 20 30 40 50 60 70 80 90
95% Bonferroni Confidence Intervals for StDevs
Figure 25
8.10
0.324
Test for equal variance for hydroxyapatite Pb mM concentration. P-value 0.452 implies rejecting
alternative hypothesis in favor of null hypothesis
pH
Pb
-1
-1
-1
Bartlett's Test
Test Statistic
P-Value
1
1
4.71
0.452
-1
1
-1
-1
1
-1
1
0
2
4
6
8
10
12
95% Bonferroni Confidence Intervals for StDevs
Figure 26
Test for equal variance for hydroxyapatite Pb mM concentration. P-value 0.782 implies rejecting
alternative hypothesis in favor of null hypothesis.
pH
Pb
-1
-1
-1
Bartlett's Test
Test Statistic
P-Value
1
1
-1
1
-1
-1
1
-1
1
0
2
4
6
8
10 12 14 16
18
95% Bonferroni Confidence Intervals for StDevs
Figure 27
2.46
0.782
Conclusion
a) For the lead response of the Fishbone apatite concentration of Pb and apatite amount is
important factor. F-value for Pb concentration is highest. Factor effects were calculated
using formula given in the book (example 6.1) The following table constructed
Fishbone
Pb
abc
ab
ac
A
bc
B
C
(1)
Factor
effects
A
B
C
Fishbone
Replicate
Pb
1
1.82
0.01
1.11
0
2.11
0.03
1.7
0.05
Replicat
e2
1.81
0
1.04
0.01
2.18
0.05
1.69
0.05
Total
3.63
0.01
2.15
0.01
4.29
0.08
3.39
0.1
b) The standard residuals are generated after
eliminating interaction with very small F-value
compare to F-value of other factors and interactions.
These standard residuals are then tested for normal
distribution hypothesis. As seen from Figure 6 pvalue generated is 0.055 which is greater than 0.05
(assumed). Figure 24 for equal variance check shows
that data is adequate with P-value 0.309. Hence the
model is adequate
-0.2575 Lowest
0.295
1.6575 Highest
Eliminate
AB
0.075 d
AC
-0.2175
BC
0.3
ABC
0.07
Eliminate
Replicat Replicat
Fishbone pH e 1
ed 2
Total
c) For pH response of the Fishbone apatite,
abc
5.22
5.12
10.34
concentration of Pb and pH are more important than others. Factor effects are calculated
abas shown 6.84
6.61 table.13.45
in the following
ac
3.35
3.34
6.69
Fihbone
a
5.77
6.25
12.02
pH
bc
5.29
5.06
10.35
b
5.93
6.02
11.95
c
3.39
3.34
6.73
(1)
4.5
4.74
9.24
Factor
effects
0.5287
A
5
1.4262
B
5 Highest
1.5687
C
5 Lowest
0.1562 Eliminat
AB
5 ed
AC
0.5412
BC
ABC
5
0.3912
5
0.1637 Eliminat
5 ed
d) After eliminating non influencing factors and generating standard residuals and testing
them for normality assumption, P-values obtained is 0.245 which is greater than 0.05.
Therefore the data is normal and model is adequate, Shown in Figure 11. Also Figure 25
shows that model has equal variance implies adequate model with P-value of 0.324.
e) For the lead response of the Hydroxyapatite apatite, concentration of Pb and amount of
apatite were important factor. Factor effects also suggest the same conclusion as shown in
table below.
Hydroxyap
Replicat
Hydroxyapat atite
e Pb
ite Pb
1
abc
0.11
ab
0
ac
0.8
a
0.03
bc
1.03
b
0
c
1.34
(1)
0.06
Factor
effects
A
-0.3675
B
-0.2575
C
0.7825
AB
-0.095
AC
-0.355
BC
-0.205
ABC
-0.1075
Replica
te 2
0.12
0
0.76
0.05
1.05
0
1.26
0.07
Total
0.23
0
1.56
0.08
2.08
0
2.6
0.13
Lowest
Highest
Eliminated
Eliminated
f) After eliminating interactions with very small F-value as compare to others the standard
residuals are tested for normality. P-value of 0.171 in Figure 15 suggests that model is
adequate. Also test for equal variance as shown in Figure 26 also suggests that model is
adequate with P-value of 0.452.
g) For the pH response of the Hydroxyapatite apatite, pH factor is most important among all
factor. Factor effects are shown in below mentioned table.
Hydroxyapat Hydroxyap
Replicat
atite
ite pH
e 1Pb
abc
3.49
ab
5.84
ac
2.7
a
3.36
bc
3.22
b
5.53
c
2.82
(1)
3.28
Factor
effects
A
0.145
B
1.485
C
-1.4275
AB
0.1775
AC
-0.06
Replica
te 2
3.46
5.9
2.74
3.24
3.22
5.43
2.79
3.28
Total
6.95
11.74
5.44
6.6
6.44
10.96
5.61
6.56
Highest
Lowest
Eliminate
d
BC
-0.9
ABC
-0.0075
Eliminate
d
h) After eliminating interactions with very small F-value as compare to others the standard
residuals are tested for normality. P-value of 0.966 shown in Figure 22 suggests that model
is adequate. Also test for equal variance as shown in Figure 27 suggests that model is
adequate with P-value of 0.782.
i) From above 23 designs it is observed that for given amount of apatite the fishbone and
hydroxyapatite has similar response. Also the pattern of effects of Factor in case of
fishbone and hydroxyapatite are similar. I second the authors conclusion that fishbone
apatite can replace the hydroxyapatite apatite because it is cheaper and has almost
similar effects as that of hydroxyapatite.
References:
[1 W. B. Brentlinger, W. B. Leonard and M. Lee, Artists, New Lamar Universtiy Logo 2013. [Art].
] Lamar University, 1982.
[2 D. C. Montgomery, Design and Analysis of Experiments, Arizona: John Wiley & Sons, INC,
] 2013.