Escolar Documentos
Profissional Documentos
Cultura Documentos
CAS No
Agent
026148-68-5
000083-32-9
025732-74-5
000075-07-0
000075-07-0
A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole)
Acenaphthene
Acepyrene (3,4-dihydrocyclopenta[cd]pyrene)
Acetaldehyde
Acetaldehyde associated with consumption of alcoholic
beverages
Acetamide
Acetaminophen (see Paracetamol)
Acheson process, occupational exposure associated with
Aciclovir
Acid mists, strong inorganic
Acridine orange
Acriflavinium chloride
Acrolein
Acrylamide
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Acrylic acid
Acrylic fibres
Acrylonitrile
Acrylonitrile-butadiene-styrene copolymers
Actinomycin D
Adriamycin
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
AF-2 [2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide]
Aflatoxins
000060-35-5
000103-90-2
059277-89-3
000494-38-2
008018-07-3
000107-02-8
000079-06-1
000079-10-7
000107-13-1
000050-76-0
023214-92-8
003688-53-7
001402-68-2
Group
006795-23-9 Aflatoxin M1
002757-90-6 Agaritine
Alcoholic beverages
000116-06-3 Aldicarb
000309-00-2 Aldrin
Aloe vera, whole leaf extract
000107-05-1 Allyl chloride
000057-06-7 Allyl isothiocyanate
002835-39-4 Allyl isovalerate
Alpha particles (see Radionuclides)
Aluminium production
Year
2B
3
3
2B
1
40, Sup 7
92
92
36, Sup 7, 71
100E
1987
2010
2010
1999
2012
2B
7, Sup 7, 71
1999
1
3
1
3
3
3
2A
111
76
54, 100F
16, Sup 7
13, Sup 7
63, Sup 7
60, Sup 7
3
3
2B
3
3
2A
19, Sup 7, 71
19, Sup 7
71
19, Sup 7
10, Sup 7
10, Sup 7
1999
1987
1999
1987
1987
1987
2B
1
31, Sup 7
56, 82, 100F,
Sup 7
56
31, Sup 7
44, 96, 100E
53
5, Sup 7
108
36, Sup 7, 71
73, Sup 7
36, Sup 7, 71
1987
2012
2B
3
1
3
3
2B
3
3
3
1
Volume
34, Sup 7,
92, 100F
In prep
2000
2012
1987
1987
1995
1994
1993
1987
2012
1991
1987
in prep
1999
1999
1999
2012
Agent
000915-67-3
004657-93-6
000117-79-3
000060-09-3
000097-56-3
000150-13-0
000092-67-1
Amaranth
5-Aminoacenaphthene
2-Aminoanthraquinone
para-Aminoazobenzene
ortho-Aminoazotoluene
para-Aminobenzoic acid
4-Aminobiphenyl
3
3
3
2B
2B
3
1
000081-49-2
000082-28-0
000712-68-5
000099-57-0
000121-88-0
000119-34-6
000121-66-4
002432-99-7
000061-82-5
1-Amino-2,4-dibromoanthraquinone
1-Amino-2-methylanthraquinone
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole
2-Amino-4-nitrophenol
2-Amino-5-nitrophenol
4-Amino-2-nitrophenol
2-Amino-5-nitrothiazole
11-Aminoundecanoic acid
Amitrole
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
Ampicillin
Amsacrine
Androgenic (anabolic) steroids
Anaesthetics, volatile
Angelicin plus ultraviolet A radiation
Aniline
ortho-Anisidine
para-Anisidine
Anthanthrene
Anthracene
Anthranilic acid
Anthraquinone
Antimony trioxide
Antimony trisulfide
Apholate
para-Aramid fibrils
Aramite
Areca nut
000069-53-4
051264-14-3
000523-50-2
000062-53-3
000090-04-0
000104-94-9
000191-26-4
000120-12-7
000118-92-3
000084-65-1
001309-64-4
001345-04-6
000052-46-0
024938-64-5
000140-57-8
Group
Volume
Year
2B
3
2B
3
3
3
3
3
3
8, Sup 7
16, Sup 7
27, Sup 7
8, Sup 7
8, Sup 7
16, Sup 7
1, Sup 7, 99,
100F
101
27, Sup 7
7, Sup 7
57
57
16, Sup 7
31, Sup 7
39, Sup 7
79, Sup 7
1987
1987
1987
1987
1987
1987
2012
2013
1987
1987
1993
1993
1987
1987
1987
2001
3
2B
2A
3
3
3
2B
3
3
3
3
2B
2B
3
3
3
2B
1
50
76
Sup 7
11, Sup 7
40, Sup 7
27, Sup 7
Sup 7, 73
27, Sup 7
92, Sup 7
92, Sup 7
16, Sup 7
101
47
47
9, Sup 7
68
5, Sup 7
85, 100E
1990
2000
1987
1987
1987
1987
1999
1987
2010
2010
1987
2013
1989
1989
1987
1997
1987
2012
Agent
Group
000151-56-4 Aziridine
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
001072-52-2 2-(1-Aziridinyl)ethanol
000800-24-8 Aziridyl benzoquinone
000103-33-3 Azobenzene
000202-94-8 11H-Benz[bc]aceanthrylene
000202-33-5 Benz[j]aceanthrylene
(NB: Overall evaluation upgraded to Group 2B with
supporting mechanistic and other relevant data)
Year
82, 100A
2012
1
1
82, 100A
23, Sup 7,
100C
100C
2012
2012
58
1993
14, Sup 7,
100C
2012
53, 73
1999
1, Sup 7, 99,
100F
Sup 7, 99,
100F
13, Sup 7
50
2012
3
2A
2B
1
012192-57-3 Aurothioglucose
000320-67-2 Azacitidine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000115-02-6 Azaserine
000446-86-6 Azathioprine
Volume
3
2A
2B
1
2012
2012
1987
1990
1987
2012
2B
10, Sup 7
26, Sup 7,
100A
9, Sup 7, 71
3
3
3
3
2B
9, Sup 7
9, Sup 7
8, Sup 7
92
92
1987
1987
1987
2010
2010
1999
Agent
Group
000211-91-6 Benz[l]aceanthrylene
000225-11-6 Benz[a]acridine
3
3
000225-51-4 Benz[c]acridine
000056-55-3 Benz[a]anthracene
000071-43-2 Benzene
000214-17-5
000196-78-1
000203-33-8
000205-99-2
000203-12-3
000205-82-3
000207-08-9
000238-84-6
000243-17-4
000205-12-9
000271-89-6
000239-35-0
000191-24-2
000195-19-7
000119-61-9
000050-32-8
000192-97-2
000105-11-3
000094-36-0
000140-11-4
001694-09-3
007440-41-7
2010
2013
3
3
3
2B
3
2B
2B
3
3
3
2B
3
3
2B
92
92
92, Sup 7
92
92, Sup 7
92
92
92, Sup 7
92, Sup 7
92, Sup 7
63
103
92, Sup 7
92, Sup 7
2010
2010
2010
2010
2010
2010
2010
2010
2010
2010
1995
2013
2010
2010
2B
1
101
Sup 7, 92,
100F
2013
2012
3
3
3
3
2B
1
92, Sup 7
29, Sup 7, 71
36, Sup 7, 71
40, Sup 7, 71
16, Sup 7
Sup 7, 58,
100C
2010
1999
1999
1999
1987
2012
Year
92
32, Sup 7,
103
32, Sup 7,
103
92, Sup 7
29, Sup 7.
100F
29, Sup 7,
99, 100F
99, 100F
2B
1
000092-87-5 Benzidine
Volume
2013
2010
2012
2012
2012
002168-68-5
003296-90-0
000111-44-4
000494-03-1
Agent
Group
000154-93-8
013483-18-6
056894-91-8
000542-88-1
000107-30-2
000108-60-1 Bis(2-chloro-1-methylethyl)ether
002386-90-5 Bis(2,3-epoxycyclopentyl)ether
000117-81-7 Bis(2-ethylhexyl) phthalate (see Di(2-ethylhexyl)
phthalate)
001675-54-3 Bisphenol A diglycidyl ether (Araldite)
Bisulfites
008052-42-4 Bitumens, extracts of steam-refined and air-refined;
steam-refined, cracking-residue and air-refined
bitumens
(see Bitumens, occupational exposures)
Bitumens, occupational exposure to hard bitumens and
their emissions during mastic asphalt work
064742-93-4 Bitumens, occupational exposure to oxidized bitumens
and their emissions during roofing
008052-42-4 Bitumens, occupational exposure to straight-run bitumens
064741-56-6 and their emissions during road paving
BK polyomavirus (BKV)
011056-06-7 Bleomycins
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
000129-17-9 Blue VRS
Boot and shoe manufacture and repair (see Leather dust,
Benzene)
Bracken fern
003844-45-9 Brilliant Blue FCF, disodium salt
Volume
Year
2A
Sup 7, 85,
100E
Sup 7, 85,
100E
95
2012
2010
3
2B
3
9, Sup 7
77
9, Sup 7, 71
1987
2000
1999
2A
3
3
1
26, Sup 7
15; Sup 7, 71
15; Sup 7, 71
4, Sup 7,
100F
1987
1999
1999
2012
3
3
41, Sup 7, 71
47, 71
1999
1999
3
3
47, 71
54
35, Sup 7
1999
1992
1987
2B
103
2013
2A
103
2013
2B
103
2013
2B
2B
104
26, Sup 7
2013
1987
16, Sup 7
25, Sup 7
1987
1987
2B
3
40, Sup 7
16, Sup 7
1987
1987
2012
Agent
005589-96-8
083463-62-1
000075-27-4
000074-96-4
000075-25-2
000055-98-1
Bromochloroacetic acid
Bromochloroacetonitrile
Bromodichloromethane
Bromoethane
Bromoform
Busulfan
Group
2B
3
2B
3
3
1
000106-99-0 1,3-Butadiene
000055-98-1
000111-76-2
057018-52-7
000141-32-2
025013-16-5
000128-37-0
000085-68-7
003068-88-0
000096-48-0
007440-43-9
000331-39-5
000058-08-2
000056-25-7
000105-60-2
002425-06-1
000133-06-2
000063-25-2
000086-74-8
020073-24-9 3-Carbethoxypsoralen
001333-86-4 Carbon black
Carbon electrode manufacture
308068-56-6 Carbon nanotubes, multi-walled MWCNT-7
308068-56-6 Carbon nanotubes, multi-walled, other than MWCNT-7
308068-56-6 Carbon nanotubes, single-walled
000056-23-5 Carbon tetrachloride
003567-69-9 Carmoisine
Year
101
52, 71
52, 71
52, 71
52, 71
4, Sup 7,
100A
Sup 7, 54,
71, 97, 100F
2013
1999
1999
1999
1999
2012
3
3
3
2B
3
3
2B
3
1
2B
3
3
3
4
2A
88
88
39, Sup 7, 71
40, Sup 7
40, Sup 7
Sup 7, 73
11, Sup 7, 71
11, Sup 7, 71
58, 100C
56
51
92
10, Sup 7
39, Sup 7, 71
53
2006
2006
1999
1987
1987
1999
1999
1999
2012
1993
1991
2010
1987
1999
1991
3
3
2B
30, Sup 7
12, Sup 7
32, Sup 7,
71, 103
40, Sup 7
Sup 7, 65, 93
92
111
111
111
20, Sup 7, 71
8, Sup 7
1987
1987
2013
Volume
3
2B
2A
2B
3
3
2B
3
2012
1987
2010
2010
In prep
In prep
In prep
1999
1987
053973-98-1
009000-07-1
000120-80-9
000075-87-6
000302-17-0
000305-03-3
Agent
Group
2B
2B
3
2B
000107-14-2
000106-47-8
000510-15-6
000124-48-1
077439-76-0
000075-45-6
000075-00-3
013010-47-4
Chloroacetonitrile
para-Chloroaniline
Chlorobenzilate
Chlorodibromomethane
3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone
Chlorodifluoromethane
Chloroethane
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
013909-09-6 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea
(see Methyl-CCNU)
000593-70-4 Chlorofluoromethane
000067-66-3 Chloroform
Year
1987
1987
1987
1999
2010
2014
2014
2012
3
2A
25, Sup 7
31, Sup 7
31, Sup 7
15, Sup 7, 71
92
63, 84, 106
63, 84, 106
26, Sup 7,
100A
84
Sup 7, 50
2B
2B
3
2B
3
2B
Sup 7, 53, 79
20, Sup 7
30, Sup 7
48
52
48
2001
1987
1987
1990
1991
1990
2A
29, Sup 7, 71
1999
2012
3
2B
3
3
2B
3
3
2A
4, Sup 7,
100A
52, 71
57
30, Sup 7
52, 71
84
41, Sup 7, 71
52, 71
26, Sup 7
1999
1993
1987
1999
2004
1999
1999
1987
3
2B
41, Sup 7, 71
Sup 7, 73
1999
1999
2A
2A
1
010599-90-3 Chloramine
000056-75-7 Chloramphenicol
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000057-74-9 Chlordane
000143-50-0 Chlordecone (Kepone)
006164-98-3 Chlordimeform
000115-28-6 Chlorendic acid
Chlorinated drinking-water
Chlorinated paraffins of average carbon chain length C12
and average degree of chlorination approximately 60%
000098-87-3 alpha-Chlorinated toluenes (benzal chloride,
000098-07-7 benzotrichloride, benzyl chloride) and benzoyl chloride
(combined exposures)
000100-44-7
000098-88-4
000494-03-1 Chlornaphazine
Volume
2004
1990
Agent
Group
Chrysene
Chrysoidine
CI Acid Orange 3
CI Acid Orange 20
CI Acid Red 114
CI Basic Red 9
CI Direct Black 38 (see Benzidine, dyes metabolized to)
CI Direct Blue 6 (see Benzidine, dyes metabolized to)
CI Direct Blue 15
CI Direct Brown 95 (see Benzidine, dyes metabolized to)
CI Orange G
CI Pigment Red 3
Ciclosporin
Volume
Year
2B
3
3
63
63
65
1995
1995
1996
2B
3
2B
2B
3
3
2B
2A
3
3
2A
41, Sup 7
27, Sup 7
27, Sup 7
Sup 7, 71
12, Sup 7
13, Sup 7
Sup 7, 73
77, 99
77, 99
41, Sup 7, 71
50
1987
1987
1987
1999
1987
1987
1999
2010
2010
1999
1990
1987
1990
1990
2012
2B
3
3
3
2B
2B
31, Sup 7
Sup 7, 49
49
Sup 7, 49,
100C
92
8, Sup 7
57
8, Sup 7
57
57, 99
2010
1987
1993
1987
1993
2010
2B
57
1993
8, Sup 7
57
50, 100A
1987
1993
2012
3
3
3
1
3
3
1
Agent
Group
051481-61-9 Cimetidine
000087-29-6 Cinnamyl anthranilate
015663-27-1 Cisplatin
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000518-75-2 Citrinin
006358-53-8 Citrus Red No. 2
000637-07-0 Clofibrate
000050-41-9 Clomiphene citrate
Clonorchis sinensis (infection with)
Coal, indoor emissions from household combustion of
Coal dust
Coal gasification
008007-45-2 Coal tars (see Coal-tar distillation)
008007-45-2 Coal-tar distillation
065996-93-2 Coal-tar pitch
010380-28-6
000191-07-1
000091-64-5
008001-58-9
000102-50-1
000120-71-8
004170-30-3
Year
3
3
2A
50
Sup 7, 77
26, Sup 7
1990
2000
1987
3
2B
3
3
1
1
3
1
1987
1987
1996
1987
2012
2012
1997
2012
2B
40, Sup 7
8, Sup 7
Sup 7, 66
21, Sup 7
61, 100B
95, 100E
68
Sup 7, 92,
100F
35, Sup 7
92, 100F
35, Sup 7,
100F
52
2A
86
2006
2B
2B
2B
2B
86
86
101
51
2006
2006
2013
1991
Sup 7, 92,
100F
2012
15, Sup 7
32, Sup 7, 92
Sup 7, 77
Sup 7, 92
27, Sup 7
27, Sup 7
63
1987
1987
2000
2010
1987
1987
1995
1
1
Volume
3
3
3
2A
3
2B
3
1987
2012
2012
1991
Agent
Group
008002-05-9
000098-82-8
014901-08-7
000139-05-9
012663-46-6
000108-94-1
000202-98-2
027208-37-3
Crude oil
Cumene
Cycasin
Cyclamates (sodium cyclamate)
Cyclochlorotine
Cyclohexanone
4H-Cyclopenta[def]chrysene
Cyclopenta[cd]pyrene
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
007099-43-6 5,6-Cyclopenteno-1,2-benzanthracene
000050-18-0 Cyclophosphamide
006055-19-2
059865-13-3 Cyclosporine (see ciclosporin)
079217-60-0
004342-03-4 Dacarbazine
005160-02-1 D & C Red No. 9
000117-10-2 Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone)
000080-08-0 Dapsone
020830-81-3 Daunomycin
000050-29-3 DDT (4,4'-Dichlorodiphenyltrichloroethane)
001163-19-5 Decabromodiphenyl oxide
052918-63-5 Deltamethrin
000083-63-6 Diacetylaminoazotoluene
000613-35-4 N,N'-Diacetylbenzidine
002303-16-4 Diallate
000615-05-4 2,4-Diaminoanisole
000101-80-4 4,4'-Diaminodiphenyl ether
000099-56-9 1,2-Diamino-4-nitrobenzene
005307-14-2 1,4-Diamino-2-nitrobenzene
000095-80-7 2,4-Diaminotoluene
000095-70-5 2,5-Diaminotoluene
000439-14-5 Diazepam
000334-88-3 Diazomethane
000226-36-8 Dibenz[a,h]acridine
000224-42-0 Dibenz[a,j]acridine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
10
Volume
Year
3
2B
2B
3
3
3
3
2A
45
101
10, Sup 7
Sup 7, 73
10, Sup 7
47, 71
92
Sup 7, 92
1989
2013
1987
1999
1987
1999
2010
2010
3
1
92
26, Sup 7,
100A
2010
2012
2B
3
2B
3
2B
2B
3
3
3
2B
3
2B
2B
3
3
2B
3
3
3
2B
26, Sup 7
Sup 7, 57
50
24, Sup 7
10, Sup 7
Sup 7, 53
48, 71
53
8, Sup 7
16, Sup 7
30, Sup 7
Sup 7, 79
29, Sup 7
16, Sup 7
Sup 7, 57
16, Sup 7
16, Sup 7
Sup 7, 66
7, Sup 7
32, Sup 7,
103
32, Sup 7,
103
1987
1993
1990
1987
1987
1991
1999
1991
1987
1987
1987
2001
1987
1987
1993
1987
1987
1996
1987
2013
2A
2013
Agent
Group
000224-53-3 Dibenz[c,h]acridine
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
000215-58-7 Dibenz[a,c]anthracene
000053-70-3 Dibenz[a,h]anthracene
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000224-41-9 Dibenz[a,j]anthracene
000194-59-2 7H-Dibenzo[c,g]carbazole
000262-12-4
005385-75-1
000207-83-0
000192-47-2
000192-65-4
000189-64-0
000189-55-9
000191-30-0
3
3
3
3
3
2B
2B
2A
000192-51-8
000132-65-0
000631-64-1
003252-43-5
000096-12-8
000096-13-9
000079-43-6
003018-12-0
007572-29-4
000541-73-1
000095-50-1
000106-46-7
000091-94-1
000110-57-6
028434-86-8
000107-06-2
000075-09-2
Dibenzo-para-dioxin
Dibenzo[a,e]fluoranthene
13H-Dibenzo[a,g]fluorene
Dibenzo[h,rst]pentaphene
Dibenzo[a,e]pyrene
Dibenzo[a,h]pyrene
Dibenzo[a,i]pyrene
Dibenzo[a,l]pyrene
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Dibenzo[e,l]pyrene
Dibenzothiophene
Dibromoacetic acid
Dibromoacetonitrile
1,2-Dibromo-3-chloropropane
2,3-Dibromopropan-1-ol
Dichloroacetic acid
Dichloroacetonitrile
Dichloroacetylene
meta-Dichlorobenzene
ortho-Dichlorobenzene
para-Dichlorobenzene
3,3'-Dichlorobenzidine
trans-1,4-Dichlorobutene
3,3'-Dichloro-4,4'-diaminodiphenyl ether
1,2-Dichloroethane
Dichloromethane (Methylene chloride)
000609-20-1 2,6-Dichloro-para-phenylenediamine
Year
2B
103
2013
3
2A
Sup 7, 92
Sup 7, 92
2010
2010
3
2B
Sup 7, 92
32, Sup 7,
103
69
Sup 7, 92
92
Sup 7, 92
Sup 7, 92
Sup 7, 92
92
Sup 7, 92
2010
2013
3
3
2B
2B
2B
2B
2B
3
3
3
3
2B
2B
3
2B
2B
2A
3
11
Volume
92
103
101
52, 71, 101
20, Sup 7, 71
77
63, 84, 106
52, 71
39, Sup 7, 71
73
Sup 7, 73
Sup 7, 73
29, Sup 7
15, Sup 7, 71
16, Sup 7
20, Sup 7, 71
Sup 7, 71,
110
39, Sup 7
1997
2010
2010
2010
2010
2010
2010
2010
2010
2013
2013
2013
1999
2000
2014
1999
1999
1999
1999
1999
1987
1999
1987
1999
in prep
1987
Agent
Group
000078-87-5 1,2-Dichloropropane
000096-23-1
000542-75-6
000062-73-7
000115-32-2
069655-05-6
000060-57-1
001464-53-5
1,3-Dichloro-2-propanol
1,3-Dichloropropene (technical-grade)
Dichlorvos
Dicofol
Didanosine
Dieldrin
1,2:3,4-Diepoxybutane (see Monographs on 1,3Butadiene)
Diesel engine exhaust (see Engine exhaust, diesel)
Diesel fuels, distillate (light)
Diesel fuel, marine
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
000111-42-2 Diethanolamine
000103-23-1 Di(2-ethylhexyl) adipate
000117-81-7 Di(2-ethylhexyl)phthalate
2B
2B
2B
3
3
3
001615-80-1 1,2-Diethylhydrazine
000056-53-1 Diethylstilbestrol
2B
1
12
Volume
Year
41, Sup 7,
71, 110
101
41, Sup 7, 71
Sup 7, 53
30, Sup 7
76
5, Sup 7
11, Sup 7
in prep
2013
1999
1991
1987
2000
1987
1987
3
2B
45
45
1989
1989
2B
3
2B
2013
2000
2013
2A
77, 101
Sup 7, 77
Sup 7, 77,
101
4, Sup 7, 71
21, Sup 7,
100A
54, 71
3
2B
2B
3
2B
3
2B
3
2B
3
2B
3
2B
79
36, Sup 7, 71
108
92
10, Sup 7
24, Sup 7
54, 71
15, Sup 7
4, Sup 7
39, Sup 7
8, Sup 7
8, Sup 7
7, Sup 7
2001
1999
in prep
2010
1987
1987
1999
1987
1987
1987
1987
1987
1987
Sup 7
1999
2012
1999
1987
Agent
004063-41-6
000087-62-7
000121-69-7
000075-60-5
000119-93-7
000079-44-7
000068-12-2
000057-14-7
000540-73-8
000868-85-9
022349-59-3
000077-78-1
105735-71-5
022506-53-2
075321-20-9
042397-64-8
042397-65-9
Group
000101-25-7
000121-14-2
000606-20-2
000618-85-9
000123-91-1
000492-17-1
002475-45-8
002832-40-8
000097-77-8
001143-38-0
040762-15-0
000562-10-7
082413-20-5
Dinitrosopentamethylenetetramine
2,4-Dinitrotoluene
2,6-Dinitrotoluene
3,5-Dinitrotoluene
1,4-Dioxane
2,4'-Diphenyldiamine
Disperse Blue 1
Disperse Yellow 3
Disulfiram
Dithranol
Doxefazepam
Doxylamine succinate
Droloxifene
Dry cleaning (occupational exposures in)
000150-69-6 Dulcin
13
Volume
Year
3
2B
3
2B
2B
2A
Sup 7
57
57
100C
1, Sup 7
12, Sup 7, 71
1987
1993
1993
2012
1987
1999
3
2B
2A
47, 71
4, Sup 7, 71
4, Sup 7, 71
1999
1999
1999
3
3
2A
48, 71
Sup 7, 92
4, Sup 7, 71
1999
2010
1999
2B
2B
2B
2B
2B
2013
2013
2013
2013
2013
3
2B
2B
3
2B
3
2B
3
3
3
3
3
3
2B
3
1987
1996
1996
1996
1999
1987
1990
1990
1987
1987
1996
2001
1996
1995
1987
000072-20-8
015086-94-9
000106-89-8
000106-88-7
000141-37-7
024560-98-3
066733-21-9
Agent
Group
029975-16-4 Estazolam
Estrogen therapy, postmenopausal (see Estrogen-only
menopausal therapy)
Estrogen-only menopausal therapy
Estrogen-progestogen menopausal therapy (combined)
Estrogen-progestogen oral contraceptives (combined)
(NB: There is also convincing evidence in humans that
these agents confer a protective effect against cancer in
the endometrium and ovary)
000064-17-5 Ethanol in alcoholic beverages
000536-33-4 Ethionamide
000140-88-5 Ethyl acrylate
000100-41-4 Ethylbenzene
000051-79-6 Ethyl carbamate (Urethane)
000074-85-1 Ethylene
000106-93-4 Ethylene dibromide
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000075-21-8 Ethylene oxide
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
14
Volume
Year
3
3
3
1
2B
3
2A
80
80
5, Sup 7
46, 105
46, 105
15, Sup 7
11, Sup 7, 71
2002
2002
1987
2013
2013
1987
1999
2B
47, 71
1999
11, Sup 7, 71
1999
3
1
1
1999
2012
2012
11, Sup 7, 71
70, 100B
42, Sup 7,
100C
66
1
1
1
72, 100A
72, 91, 100A
72, 91, 100A
2012
2012
2012
1
3
2B
2B
2A
3
2A
96, 100E
13, Sup 7
39, Sup 7, 71
77
7, Sup 7, 96
Sup 7, 60
15, Sup 7, 71
2012
1987
1999
2000
2010
1994
1999
Sup 7, 60,
97, 100F
2012
1996
Agent
Group
15
Volume
Year
3
3
11, Sup 7
Sup 7, 79
1987
2001
3
2B
2A
60
7, Sup 7
17, Sup 7
1994
1987
1987
3
3
1
12, Sup 7
12, Sup 7
76, 100A
1987
1987
2012
76, 100A
2012
3
3
3
3
3
3
2B
1
3
3
3
3
3
3
1
3
36, Sup 7
8, Sup 7
16, Sup 7
53
12, Sup 7
1, Sup 7
98
100D
58
30, Sup 7
Sup 7, 92
Sup 7, 92
55
27, Sup 7
111
26, Sup 7
1987
1987
1987
1991
1987
1987
2010
2012
1993
1987
2010
2010
1992
1987
In prep
1987
Sup 7, 62,
88, 100F
7, Sup 7
95
45
2012
2B
2A
3
1987
2010
1989
116355-83-0
000110-00-9
000067-45-8
000098-01-1
000054-31-9
116355-83-0
001303-00-0
025812-30-0
090045-36-6
067730-11-4
067730-10-3
000765-34-4
000556-52-5
005431-33-4
007460-84-6
000126-07-8
004680-78-8
016568-02-8
001317-60-8
Agent
Group
16
2B
2B
2B
3
3
Volume
Year
45
82
63
31, Sup 7
63
25, Sup 7
50
Sup 7, 56
1989
2002
1995
1987
1995
1987
1990
1993
56
1993
56
86, 100C
1993
2012
2B
45
1989
3
2B
3
2B
66
108
43, 81
40, Sup 7
2B
2B
2A
40, Sup 7
11, Sup 7, 71
77
3
3
2B
2B
3
3
3
1
11, Sup 7
11, Sup 7
108
Sup 7, 79
16, Sup 7
31, Sup 7
1, Sup 7
1, Sup 7,
100D
57, 99
3
3
2B
3
1996
in prep
2002
1987
1987
1999
2000
1987
1987
in prep
2001
1987
1987
1987
2012
2010
002784-94-3
033229-34-4
002871-01-4
059820-43-8
000076-44-8
000118-74-1
000087-68-3
000067-72-1
000070-30-4
000142-83-6
000680-31-9
Agent
Group
17
Volume
Year
2A
2B
3
3
3
1
1
1
3
2B
2B
3
2B
2B
3
2B
2B
57, 99
57
57
57
57
61, 100B
59, 100B
59, 100B
59
Sup 7, 53, 79
Sup 7, 79
73
20, Sup 7
73
20, Sup 7
101
15, Sup 7, 71
2010
1993
1993
1993
1993
2012
2012
2012
1994
2001
2001
1999
1987
1999
1987
2013
1999
1
2B
3
67, 100B
67
90, 100B
2012
1996
2012
2B
100B
2012
90, 100B
64, 90, 100B
2012
2012
100B
2012
3
1
2B
023255-93-8
000086-54-4
000302-01-2
007647-01-0
000058-93-5
007722-84-1
000123-31-9
000129-43-1
001689-82-3
000148-24-3
026782-43-4
000127-07-1
000193-39-5
022398-80-7
010043-66-0
076180-96-6
009004-66-4
009004-51-7
001338-16-5
015503-86-3
000054-85-3
003778-73-2
000078-79-5
000067-63-0
Agent
Group
2B
100B
2A
1
3
3
3
2B
3
2B
3
3
2B
3
3
3
3
3
2B
2A
100B
67, 100B
67
13, Sup 7
24, Sup 7
4, Sup 7, 71
54
50, 108
36, Sup 7, 71
15, Sup 7, 71
82
8, Sup 7
13, Sup 7
10, Sup 7
76
52
Sup 7, 92
86
1
2A
1
2B
3
3
3
3
3
2B
3
18
Volume
Year
2012
2012
2012
1996
1987
1987
1999
1992
in prep
1999
1999
2002
1987
1987
1987
2000
1991
2010
2006
43, 81
2002
100D
Sup 7, 56
2012
1993
34, Sup 7,
100F
2, Sup 7
2, Sup 7
2, Sup 7
10, Sup 7
4, Sup 7
26, Sup 7
60, 71
15, Sup 7, 71
2012
1987
1987
1987
1987
1987
1987
1999
1999
000120-58-1
006870-67-3
000520-18-3
009000-38-8
000501-30-4
000303-34-4
000105-74-8
007439-92-1
005141-20-8
005989-27-5
021884-44-6
000632-99-5
Agent
Group
1
3
3
3
2B
3
3
1
2B
3
2B
3
2B
2A
3
19
Year
Sup 7, 100F
15, Sup 7, 71
10, Sup 7
10, Sup 7
104
45
31, Sup 7
70, 100B
108
79
10, Sup 7
36, Sup 7, 71
23, Sup 7
Sup 7, 87
23, Sup 7, 87
2012
1999
1987
1987
2013
1989
1987
2012
in prep
2001
1987
1999
1987
2006
2006
1
3
3
3
3
100C
25, Sup 7
25, Sup 7
16, Sup 7
56, 73
2012
1987
1987
1987
1999
3
3
3
2B
1987
1987
2002
2012
2B
3
2A
25, Sup 7
10, Sup 7
82
Sup 7, 57,
99, 100F
Sup 7, 57,
99, 100F
80
80
104
3
3
30, Sup 7
4, Sup 7
1987
1987
Volume
2012
2002
2002
2013
Agent
Group
000542-78-9 Malonaldehyde
012427-38-2 Maneb
000551-74-6 Mannomustine dihydrochloride
Mate
Mate, hot
068006-83-7 MeA-alpha-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole)
013045-94-8 Medphalan
000071-58-9 Medroxyprogesterone acetate
077094-11-2 MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline)
077500-04-0 MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline)
000108-78-1 Melamine
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
000148-82-3 Melphalan
3
3
3
3
2A
2B
3
2B
2B
2B
3
000050-44-2 6-Mercaptopurine
007439-97-6 Mercury and inorganic mercury compounds
Merkel cell polyomavirus (MCV)
000531-76-0 Merphalan
Metabisulfites
000060-56-0 Methimazole
000059-05-2 Methotrexate
000072-43-5 Methoxychlor
000298-81-7 Methoxsalen (8-methoxypsoralen) plus ultraviolet A
radiation
000484-20-8 5-Methoxypsoralen
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000096-33-3 Methyl acrylate
073459-03-7 5-Methylangelicin plus ultraviolet A radiation
000124-58-3 Methylarsonic acid
000075-55-8 2-Methylaziridine (Propyleneimine)
000592-62-1 Methylazoxymethanol acetate
000074-83-9 Methyl bromide
001634-04-4 Methyl tert-butyl ether
000598-55-0 Methyl carbamate
013909-09-6 Methyl-CCNU
000074-87-3 Methyl chloride
003351-28-8 1-Methylchrysene
3
3
2A
2B
3
3
3
3
1
20
Volume
Year
36, Sup 7, 71
12, Sup 7
9, Sup 7
51
51
40, Sup 7
9, Sup 7
21, Sup 7
Sup 7, 56
Sup 7, 56
Sup 7, 73
1999
1987
1987
1991
1991
1987
1987
1987
1993
1993
1999
2012
1987
1993
2013
1987
1992
2001
1987
1987
2012
2A
9, Sup 7,
100A
26, Sup 7
58
104
9, Sup 7
54
79
26, Sup 7
20, Sup 7
24, Sup 7,
100A
40, Sup 7
3
3
2B
2B
2B
3
3
3
1
3
3
39, Sup 7, 71
Sup 7
100C
9, Sup 7, 71
10, Sup 7
41, Sup 7, 71
73
12, Sup 7
Sup 7, 100A
41, Sup 7, 71
Sup 7, 92
1999
1987
2012
1999
1987
1999
1999
1987
2012
1999
2010
1987
Agent
003351-32-4
003351-31-3
003351-30-2
003697-24-3
001705-85-7
000099-80-9
000101-14-4
2-Methylchrysene
3-Methylchrysene
4-Methylchrysene
5-Methylchrysene
6-Methylchrysene
N-Methyl-N,4-dinitrosoaniline
4,4'-Methylenebis(2-chloroaniline) (MOCA)
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
4,4'-Methylene bis(2-methylaniline)
Methylene blue
4,4'-Methylenedianiline
4,4'-Methylenediphenyl diisocyanate
Methyleugenol
2-Methylfluoranthene
3-Methylfluoranthene
Methylglyoxal
2-Methylimidazole
4-Methylimidazole
Methyl iodide
Methyl isobutyl ketone
Methylmercury compounds
(NB: Evaluated as a group)
Methyl methacrylate
Methyl methanesulfonate
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
2-Methyl-1-nitroanthraquinone (uncertain purity)
N-Methyl-N-nitro-N-nitrosoguanidine (MNNG)
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
N-Methyl-N-nitrosourea
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
N-Methyl-N-nitrosourethane
N-Methylolacrylamide
Methyl parathion
1-Methylphenanthrene
7-Methylpyrido[3,4-c]psoralen
Methyl red
000838-88-0
007220-79-3
000101-77-9
000101-68-8
000093-15-2
033543-31-6
001706-01-0
000078-98-8
000693-98-1
000822-36-6
000074-88-4
000108-10-1
000080-62-6
000066-27-3
000129-15-7
000070-25-7
000684-93-5
000615-53-2
090456-67-0
000298-00-0
000832-69-9
085878-63-3
000493-52-7
Group
21
Volume
Year
3
3
3
2B
3
3
1
Sup 7, 92
Sup 7, 92
Sup 7, 92
Sup 7, 92
Sup 7, 92
1, Sup 7
Sup 7, 57,
99, 100F
2010
2010
2010
2010
2010
1987
2012
2B
3
2B
3
2B
3
3
3
2B
2B
3
2B
2B
4, Sup 7
108
39, Sup 7
19, Sup 7, 71
101
Sup 7, 92
Sup 7, 92
51
101
101
41, Sup 7, 71
101
58
1987
in prep
1987
1999
2013
2010
2010
1991
2013
2013
1999
2013
1993
3
2A
Sup 7, 60
7, Sup 7, 71
1994
1999
2B
2A
27, Sup 7
4, Sup 7
1987
1987
2A
17, Sup 7
1987
2B
3
3
3
3
3
4, Sup 7
60
30, Sup 7
Sup 7, 92
40, Sup 7
8, Sup 7
1987
1994
1987
2010
1987
1987
Agent
Group
22
Volume
Year
3
2B
12, Sup 7
101
1987
2013
2B
2B
2B
Sup 7, 79
13, Sup 7
27, Sup 7, 99
2001
1987
2010
2B
2B
3
3
1
2010
2010
2010
1987
2012
2B
2B
2B
3
2B
2B
2B
3
1
99
94
94
33, Sup 7
33, Sup 7,
100F
20, Sup 7
10, Sup 7
76
19, Sup 7
101
10, Sup 7
100C
Sup 7, 53
Sup 7, 100A
1987
1987
2000
1987
2013
1987
2012
1991
2012
3
2B
47, 71
7, Sup 7
1999
1987
65
65
1996
1996
24, Sup 7
82
27, Sup 7
19, Sup 7, 71
92
92
1987
2002
1987
1999
2010
2010
3
3
2B
2B
3
3
3
3
Agent
Group
000193-09-9 Naphtho[2,3-e]pyrene
000134-32-7 1-Naphthylamine
000091-59-8 2-Naphthylamine
3
3
1
3
3
1
2B
1
Volume
92
4, Sup 7
4, Sup 7, 99,
100F
30, Sup 7
31, Sup 7
75, 100D
Year
2010
1987
2012
1987
1987
2012
2B
2A
Sup 7, 49
Sup 7, 49,
100C
11
13, Sup 7
94
1990
2012
1976
1987
2010
2B
48, 73
1999
000602-87-9
000099-59-2
000091-23-6
000602-60-8
017117-34-9
000098-95-3
020268-51-3
063041-90-7
000092-93-3
007496-02-8
2B
3
2B
3
2B
2B
3
3
3
2A
1987
1987
1996
1987
2013
1996
1989
1989
1987
2013
001836-75-5
000892-21-7
000607-57-8
000059-87-0
000067-20-9
000555-84-0
000531-82-8
000051-75-2
000126-85-2
000075-52-5
000086-57-7
Nitrofen (technical-grade)
3-Nitrofluoranthene
2-Nitrofluorene
Nitrofural (Nitrofurazone)
Nitrofurantoin
1-[(5-Nitrofurfurylidene)amino]-2-imidazolidinone
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide
Nitrogen mustard
Nitrogen mustard N-oxide
Nitromethane
1-Nitronaphthalene
2B
3
2B
3
3
2B
2B
2A
2B
2B
3
16, Sup 7
27, Sup 7
65
33, Sup 7
105
65
46
Sup 7, 46
4, Sup 7
Sup 7, 46,
105
30, Sup 7
33, Sup 7
46, 105
50
50
7, Sup 7
7, Sup 7
9, Sup 7
9, Sup 7
77
46
000061-57-4
000139-13-9
23
1987
1987
2013
1990
1990
1987
1987
1987
1987
2000
1989
Agent
000581-89-5
020589-63-3
000079-46-9
005522-43-0
2-Nitronaphthalene
3-Nitroperylene
2-Nitropropane
1-Nitropyrene
3
3
2B
2A
000789-07-1
057835-92-4
037620-20-5
071267-22-6
000924-16-3
001116-54-7
000055-18-5
2-Nitropyrene
4-Nitropyrene
N'-Nitrosoanabasine (NAB)
N'-Nitrosoanatabine (NAT)
N-Nitrosodi-n-butylamine
N-Nitrosodiethanolamine
N-Nitrosodiethylamine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
N-Nitrosodimethylamine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
N-Nitrosodiphenylamine
para-Nitrosodiphenylamine
N-Nitrosodi-n-propylamine
N-Nitrosofolic acid
N-Nitrosoguvacine
N-Nitrosoguvacoline
N-Nitrosohydroxyproline
3-(N-Nitrosomethylamino)propionaldehyde
3-(N-Nitrosomethylamino)propionitrile
N-Nitrosomethylethylamine
N-Nitrosomethylvinylamine
N-Nitrosomorpholine
N'-Nitrosonornicotine (NNN) and 4-(NNitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK)
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
N-Nitrosopiperidine
N-Nitrosoproline
N-Nitrosopyrrolidine
N-Nitrososarcosine
2-Nitrotoluene
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000062-75-9
000086-30-6
000156-10-5
000621-64-7
029291-35-8
055557-01-2
055557-02-3
030310-80-6
085502-23-4
060153-49-3
010595-95-6
004549-40-0
000059-89-2
016543-55-8
064091-91-4
000100-75-4
007519-36-0
000930-55-2
013256-22-9
000088-72-2
Group
24
Volume
Year
1989
1989
1999
2013
3
2B
3
3
2B
2B
2A
46
46
29, Sup 7, 71
Sup 7, 46,
105
46
46, 105
37, Sup 7, 89
37, Sup 7, 89
17, Sup 7
17, Sup 7, 77
17, Sup 7
2A
17, Sup 7
1987
3
3
2B
3
3
3
3
3
2B
2B
2B
2B
1
27, Sup 7
27, Sup 7
17, Sup 7
17, Sup 7
Sup 7, 85
Sup 7, 85
17, Sup 7
Sup 7, 85
Sup 7, 85
17, Sup 7
17, Sup 7
17, Sup 7
Sup 7, 89,
100E
1987
1987
1987
1987
2004
2004
1987
2004
2004
1987
1987
1987
2012
2B
3
2B
2B
2A
17, Sup 7
17, Sup 7
17, Sup 7
17, Sup 7
101
1987
1987
1987
1987
2013
1989
2013
2007
2007
1987
2000
1987
Agent
000099-08-1
000099-99-0
000099-55-8
000804-36-4
118399-22-7
Nitrotoluenes
025038-54-4
000303-47-9
022966-79-6
002646-17-5
000523-44-4
001936-15-8
000604-75-1
000129-20-4
012174-11-7
012174-11-7
000794-93-4
000103-90-2
010048-32-5
000056-38-2
000149-29-1
Group
3
5-Nitro-ortho-toluidine
Nitrovin
Nodularins
Non-arsenical insecticides (occupational exposures in
spraying and application of)
Nylon 6
Ochratoxin A
Oestradiol mustard
Oestrogen (see Estrogen)
Oil Orange SS
Opisthorchis felineus (infection with)
Opisthorchis viverrini (infection with)
Oral contraceptives, combined estrogen-progestogen
(see Estrogen-progestogen oral contraceptives)
Orange I (see CI Acid Orange 20)
Orange G (see CI Orange G)
Outdoor air pollution
Outdoor air pollution, particulate matter in
Oxazepam
Oxyphenbutazone
Painter (occupational exposure as a)
Paint manufacture (occupational exposure in)
Palygorskite (Attapulgite) (long fibres, > 5 micrometres)
Palygorskite (Attapulgite)(short fibres, < 5 micrometres)
Panfuran S (containing dihydroxymethylfuratrizine)
Paracetamol (Acetaminophen)
Parasorbic acid
Parathion
Particulate matter in outdoor air pollution (see Outdoor air
pollution, particulate matter in)
Patulin
Paving and roofing with coal-tar pitch (see Coal-tar pitch)
25
Volume
Year
65
1996
3
3
3
2A
48
31, Sup 7
94
53
1990
1987
2010
1991
3
2B
3
19, Sup 7
Sup 7, 56
9, Sup 7
1987
1993
1987
2B
3
1
8, Sup 7
61
61, 100B
1987
1994
2012
1
1
2B
3
1
3
2B
3
2B
3
3
3
109
109
Sup 7, 66
13, Sup 7
47, 98, 100F
47
68
68
24, Sup 7
50, 73
10, Sup 7
30, Sup 7
3
1
40, Sup 7
35, Sup 7,
92, 100F
10, Sup 7
100F
in prep
in prep
1996
1987
2012
1989
1997
1997
1987
1999
1987
1987
1987
2010
1987
2012
Agent
Group
057117-31-4 2,3,4,7,8-Pentachlorodibenzofuran
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
000076-01-7 Pentachloroethane
000087-86-5 Pentachlorophenol (see Polychlorophenols)
037319-17-8 Pentosan polysulfate sodium
000335-67-1 Perfluorooctanoic acid
052645-53-1 Permethrin
000198-55-0 Perylene
060102-37-6 Petasitenine
Petroleum refining (occupational exposures in)
Petroleum solvents
Pickled vegetables (traditional in Asia)
000062-44-2 Phenacetin
(NB: Overall evaluation upgraded to Group 1 with
supporting evidence from other relevant data)
Phenacetin, analgesic mixtures containing
000085-01-8 Phenanthrene
000136-40-3 Phenazopyridine hydrochloride
000156-51-4 Phenelzine sulfate
000103-03-7 Phenicarbazide
000050-06-6 Phenobarbital
000108-95-2 Phenol
000077-09-8 Phenolphthalein
000063-92-3 Phenoxybenzamine hydrochloride
000050-33-9 Phenylbutazone
000108-45-2 meta-Phenylenediamine
000106-50-3 para-Phenylenediamine
000122-60-1 Phenyl glycidyl ether
000135-88-6 N-Phenyl-2-naphthylamine
000090-43-7 ortho-Phenylphenol
000057-41-0 Phenytoin
105650-23-5 PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine)
014596-37-3 Phosphorus-32, as phosphate
000213-46-7 Picene
001918-02-1 Picloram
111025-46-8 Pioglitazone
000051-03-6 Piperonyl butoxide
007440-07-5 Plutonium
26
Volume
Year
100F
41, Sup 7, 71
53, 71
108
110
53
Sup 7, 92
31, Sup 7
45
47
56
24, Sup 7,
100A
1999
1999
in prep
in prep
1991
2010
1987
1989
1989
1993
2012
Sup 7, 100A
Sup 7, 92
24, Sup 7
24, Sup 7
12, Sup 7
Sup 7, 79
47, 71
76
24, Sup 7
13, Sup 7
16, Sup 7
16, Sup 7
47, 71
16, Sup 7
73
Sup 7, 66
56
78, 100D
92
53
108
30, Sup 7
78, 100D
2012
2010
1987
1987
1987
2001
1999
2000
1987
1987
1987
1987
1999
1987
1999
1996
1993
2012
2010
1991
in prep
1987
2012
2B
2B
3
3
3
2A
3
2B
1
1
3
2B
3
3
2B
3
2B
2B
3
3
3
2B
3
3
2B
2B
1
3
3
2A
3
1
2012
Agent
Group
009010-98-4
009002-88-4
009016-87-9
009011-14-7
009003-07-0
009003-53-6
009002-84-0
009009-54-5
009003-20-7
009002-89-5
009002-86-2
009003-39-8
003564-09-8
003761-53-3
004548-53-2
023746-34-1
007758-01-2
002955-38-6
029069-24-7
000053-03-2
000125-33-7
27
Volume
Year
3
2A
19, Sup 7
41, Sup 7,
107
1987
in prep
in prep
18, Sup 7,
107
107
69
1997
69
1997
2B
53, 71
1999
3
3
3
3
3
3
3
3
3
3
3
3
2B
2B
3
3
2B
3
3
3
2B
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7, 71
8, Sup 7
8, Sup 7
8, Sup 7
12, Sup 7
Sup 7, 73
66
50
26, Sup 7
108
in prep
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1999
1996
1990
1987
in prep
000366-70-1
000051-02-5
001120-71-4
000122-42-9
000057-57-8
000627-12-3
000115-07-1
000075-56-9
000051-52-5
087625-62-5
000089-82-7
000129-00-0
000110-86-1
085878-62-2
000058-14-0
000117-39-5
000106-51-4
000082-68-8
013233-32-4
013982-63-3
Agent
Group
Printing inks
Printing processes (occupational exposures in)
Procarbazine hydrochloride
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Proflavine salts
Progestins
Progestogen-only contraceptives
Pronetalol hydrochloride
1,3-Propane sultone
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Propham
beta-Propiolactone
n-Propyl carbamate
Propylene
Propylene oxide
Propylthiouracil
Ptaquiloside
Pulegone
Pulp and paper manufacture
Pyrene
Pyridine
Pyrido[3,4-c]psoralen
Pyrimethamine
Quercetin
para-Quinone
Quintozene (Pentachloronitrobenzene)
Radiofrequency electromagnetic fields1
Radioiodines, including iodine-131
Radionuclides, alpha-particle-emitting, internally
deposited
(NB: Specific radionuclides for which there is sufficient
evidence in humans are also listed individually as
Group 1 agents)
Radionuclides, beta-particle-emitting, internally deposited
(NB: Specific radionuclides for which there is sufficient
evidence in humans are also listed individually as
Group 1 agents)
Radium-224 and its decay products
Radium-226 and its decay products
28
Volume
Year
3
2B
2A
65
65
26, Sup 7
1996
1996
1987
3
2B
2B
3
2A
24, Sup 7
Sup 7
72
13, Sup 7
4, Sup 7, 71,
110
1987
1987
1999
1987
in prep
3
2B
3
3
2B
2B
3
2B
3
3
3
3
3
3
3
3
2B
1
1
12, Sup 7
4, Sup 7, 71
12, Sup 7
Sup 7, 60
Sup 7, 60
Sup 7, 79
40, Sup 7
108
25, Sup 7
Sup 7, 92
77
40, Sup 7
13, Sup 7
Sup 7, 73
15, Sup 7, 71
5, Sup 7
102
78, 100D
78, 100D
1987
1999
1987
1994
1994
2001
1987
in prep
1987
2010
2000
1987
1987
1999
1999
1987
2013
2012
2012
78, 100D
2012
1
1
78, 100D
78, 100D
2012
2012
Agent
Group
1
1
2B
3
3
3
3
3
2B
3
3
3
1
Year
78, 100D
43, 78, 100D
43, 81
24, Sup 7
15, Sup 7, 71
10, Sup 7
16, Sup 7
16, Sup 7
10, Sup 7, 82
24, Sup 7
66
108
28, Sup 7,
100F
40, Sup 7
43, 81
2, Sup 7
Sup 7, 73
2012
2012
2002
1987
1999
1987
1987
1987
2002
1987
1996
in prep
2012
023537-16-8 Rugulosin
Rock (stone) wool
008047-67-4 Saccharated iron oxide
000081-07-2 Saccharin and its salts
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
000094-59-7 Safrole
Salted fish, Chinese-style
000085-83-6 Scarlet Red
Schistosoma haematobium (infection with)
Schistosoma japonicum (infection with)
Schistosoma mansoni (infection with)
007782-49-2 Selenium and selenium compounds
000563-41-7 Semicarbazide hydrochloride
013909-09-6 Semustine (see Methyl-CCNU)
000480-81-9 Seneciphylline
002318-18-5 Senkirkine
015501-74-3 Sepiolite
068308-34-9 Shale oils
2B
1
3
1
2B
3
3
3
10, Sup 7
56, 100E
8, Sup 7
61, 100B
61
61
9, Sup 7
12, Sup 7
1987
2012
1987
2012
1994
1994
1987
1987
3
3
3
1
1987
1987
1997
2012
2A
3
3
1
10, Sup 7
31, Sup 7
Sup 7, 68
35, Sup 7,
100F
98
40, Sup 7
Sup 7, 68
Sup 7, 68,
100C
29
3
3
3
3
Volume
1987
2002
1987
1999
2010
1987
1997
2012
Agent
308076-74-6
409-21-2
000122-34-9
308068-56-6
007758-19-2
000148-18-5
000132-27-4
000052-01-7
010048-13-2
018883-66-4
007664-93-9
010098-97-2
000100-42-5
009003-54-7
009003-55-8
000096-09-3
000108-30-5
000842-07-9
003118-97-6
000085-86-9
006416-57-5
006368-72-5
000127-69-5
000095-06-7
000057-68-1
000723-46-6
000599-79-1
30
Group
Volume
Year
2B
2A
3
111
111
53, 73
In prep
In prep
1999
3
3
3
2B
1
1
2002
1991
1987
1999
2012
2012
2B
43, 81
52
12, Sup 7
Sup 7, 73
55, 100D
35, Sup 7,
92, 100F
81
3
2B
2B
Sup 7, 79
10, Sup 7
17, Sup 7
2001
1987
1987
2B
3
3
2A
60, 82
19, Sup .7
19, Sup 7
Sup 7, 60
2002
1987
1987
1994
3
3
3
3
3
3
3
2B
3
15, Sup 7
8, Sup 7
8, Sup 7
8, Sup 7
8, Sup 7
8, Sup 7
24, Sup 7
30, Sup 7
79
1987
1987
1987
1987
1987
1987
1987
1987
2001
3
2B
3
Sup 7, 79
108
54
2001
in prep
1992
2002
Agent
Group
002783-94-0
022571-95-5
014807-96-6
014807-96-6
014807-96-6
010540-29-1
001401-55-4
000846-50-4
029767-20-2
008001-50-1
015721-02-5
001746-01-6
31
Volume
Year
3
1
54
9, Sup 7,
100F
1992
2012
3
2B
8, Sup 7
74
1987
1999
74
1999
3
3
3
2B
1
104
31, Sup 7
42, Sup 7
42, Sup 7, 93
93
66, 100A
2013
1987
1987
2010
2010
2012
3
3
3
2A
10, Sup 7
51
66
76
1987
1991
1996
2000
3
3
1
5, Sup 7
27, Sup 7
Sup 7, 69,
100F
1987
1987
2012
Agent
Group
000630-20-6 1,1,1,2-Tetrachloroethane
2B
000079-34-5 1,1,2,2-Tetrachloroethane
2B
2A
022248-79-9 Tetrachlorvinphos
000116-14-3 Tetrafluoroethylene
(NB: Overall evaluation upgraded to Group 2A)
Tetrakis(hydroxymethyl)phosphonium salts
000509-14-8 Tetranitromethane
Textile manufacturing industry (work in)
000083-67-0 Theobromine
000058-55-9 Theophylline
000062-55-5 Thioacetamide
000139-65-1 4,4'-Thiodianiline
000052-24-4 Thiotepa
3
2A
000141-90-2
000062-56-6
000137-26-8
007440-29-1
013463-67-7
2B
3
3
1
2B
1
Thiouracil
Thiourea
Thiram
Thorium-232 and its decay products
Titanium dioxide
Tobacco, smokeless
3
2B
2B
3
3
2B
2B
1
1
1
3
2B
1
089778-26-7 Toremifene
008001-35-2 Toxaphene (Polychlorinated camphenes)
Toxins derived from certain Fusarium species (see
Fusarium)
000299-75-2 Treosulfan
3
2B
000396-01-0 Triamterene
021259-20-1 T2-Trichothecene
000052-68-6 Trichlorfon
2B
3
3
32
Volume
41, Sup 7,
71, 106
20, Sup 7,
71, 106
Sup 7, 63,
106
30, Sup 7
19, Sup 7,
71, 110
48, 71
65
48
51
51
7, Sup 7
27, Sup 7
Sup 7, 50,
100A
Sup 7, 79
Sup 7, 79
Sup 7, 53
78, 100D
47, 93
Sup 7, 89,
100E
83, 100E
83, 100E
47, 71
39, Sup 7, 71
Sup 7, 77,
99, 100F
66
Sup 7, 79
26, Sup 7,
100A
108
31, Sup 7
30, Sup 7
Year
2014
2014
2014
1987
in prep
1999
1996
1990
1991
1991
1987
1987
2012
2001
2001
1991
2012
2010
2012
2012
2012
1999
1999
2012
1996
2001
2012
in prep
1987
1987
Agent
000817-09-4
000076-03-9
000545-06-2
000071-55-6
000079-00-5
000079-01-6
2B
2B
3
3
3
1
000096-18-4
000102-71-6
001954-28-5
001582-09-8
090370-29-9
000137-17-7
000088-05-1
003902-71-4
000118-96-7
000217-59-4
000068-76-8
000545-55-1
000051-18-3
000115-96-8
038571-73-2
000126-72-7
1,2,3-Trichloropropane
Triethanolamine
Triethylene glycol diglycidyl ether
Trifluralin
4,4',6-Trimethylangelicin plus ultraviolet A radiation
2,4,5-Trimethylaniline
2,4,6-Trimethylaniline
4,5',8-Trimethylpsoralen
2,4,6-Trinitrotoluene
Triphenylene
Tris(aziridinyl)-para-benzoquinone (Triaziquone)
Tris(1-aziridinyl)phosphine oxide
2,4,6-Tris(1-aziridinyl)-s-triazine
Tris(2-chloroethyl) phosphate
1,2,3-Tris(chloromethoxy)propane
Tris(2,3-dibromopropyl) phosphate
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Tris(2-methyl-1-aziridinyl)phosphine oxide
Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)
Trp-P-2 (3-Amino-1-methyl-5H-pyrido[4,3-b]indole)
Trypan blue
Tungsten carbide with cobalt metal (see Cobalt metal
with tungsten carbide)
000057-39-6
062450-06-0
062450-07-1
000072-57-1
012070-12-1
007440-48-4
000066-75-1
001314-62-1
000128-66-5
000143-67-9
Group
33
Volume
Year
2A
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2A
Sup 7, 50
63, 84, 106
52, 71
20, Sup 7, 71
52, 71
Sup 7, 63,
106
63
77
11, Sup 7, 71
53
Sup 7
27, Sup 7
27, Sup 7
40, Sup 7
65
Sup 7, 92
9, Sup 7
9, Sup 7
9, Sup 7
48, 71
15, Sup 7, 71
20, Sup 7, 71
1990
2014
1999
1999
1999
2014
1995
2000
1999
1991
1987
1987
1987
1987
1996
2010
1987
1987
1987
1999
1999
1999
3
2B
2B
2B
9, Sup 7
31, Sup 7
31, Sup 7
8, Sup 7
1987
1987
1987
1987
55, 100D
2012
1
2B
100D
9, Sup 7
2012
1987
2B
3
3
86
48
26, Sup 7
2006
1990
1987
Agent
Group
3
2B
2A
009003-22-9
000100-40-3
000106-87-6
000075-02-5
000075-35-4
009011-06-7
000075-38-7
000088-12-0
025013-15-4
012001-79-5
013983-17-0
001330-20-7
000095-68-1
000095-78-3
000085-84-7
000131-79-3
007481-89-2
000315-18-4
34
Volume
Year
26, Sup 7
Sup 7, 63
39, Sup 7,
71, 97
1987
1995
2008
2012
3
2B
2B
2A
Sup 7, 97,
100F
19, Sup 7
Sup 7, 60
Sup 7, 60
Sup 7, 63, 97
1987
1994
1994
2008
3
3
3
3
3
3
2B
39, Sup 7, 71
19, Sup 7
39, Sup 7, 71
19, Sup 7, 71
60
76
49
1999
1987
1999
1999
1994
2000
1990
3
1
Sup 7, 68
62, 100C
1997
2012
1
3
3
3
3
3
2B
3
75, 100D
47, 71
16, Sup 7
16, Sup 7
8, Sup 7
8, Sup 7
76
12, Sup 7
2012
1999
1987
1987
1987
1987
2000
1987
Agent
Group
35
2B
3
3
Volume
Year
68
1997
76
12, Sup 7
Sup 7, 53
2000
1987
1991