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-Drug

Generic and
Brand name,
Dose,
Frequency,
Route, Time
-Drug
classification
Ceftazidime
(Tazidem)
1gm/IV q8
(6am-2pm10pm)
Antibiotic

-Action/Use of each
drug
-*Rationale for this
patient

Contraindications

Adverse Effect

Nursing considerations

Binds to bacterial cell


membranes, inhibits cell
wall synthesis.

History of hypersensitivity
to this drug

Audra
(fenofibrate)
200mg 1 tab
OD after
dinner 8pm
Antihyperlipide
mic

Lowers plasma
triglyceride by
activating lipoprotein
lipase thus increasing
catabolism of VLDL with
consequent increase in
HDL levels.

Antibiotic-associated colitis, other


super infections (abdominal
cramps, severe
watery diarrhea, fever) may result
from
Altered bacterial balance.
Nephrotoxicity may occur, esp. in
patients with preexisting renal
disease.
Patients with a history of allergies,
esp. to penicillin, are at increased
risk for developing a severe
hypersensitivity reaction (severe
pruritus, angioedema).
Severe pain in the upper stomach
spreading to back, nausea and
vomiting, fast heart rate; easy
bruising, unusual bleeding (nose,
mouth, vagina, or rectum), purple
or red pinpoint spots under the
skin; chest pain, sudden cough,
wheezing, rapid breathing,
coughing up blood; or
Pain, swelling, warmth, or redness
in one or both legs.

Monitor daily pattern of bowel activity,


stool consistency.
Monitor I&O, renal function tests for
nephrotoxicity.
Be alert for superinfection: fever,
vomiting,
diarrhea, anal/genital pruritus, oral
mucosal
changes (ulceration, pain, erythema).
Teach SO that patients may experience
stomach upset or diarrhea but must
report severe diarrhea, difficulty
breathing, fatigue, pain at injection
site.
Obtain diet history, esp. fat
consumption.
Obtain serum cholesterol, triglycerides,
hepatic function tests (including ALT),
blood counts during initial therapy and
periodically during treatment.
Treatment should be discontinued if
hepatic enzyme levels persist greater
than 3 times the normal limit.

Liver Gold F
Sylimarin+Vita
min B complex
1 tab OD after

For all forms of hepatic


cell damage as in
cases of: 1.Chronic
persistent and chronic

Diarrhea

Monitor for adverse effects.


Tell patient to discontinue use if
adverse symptoms occur & not
improved w/in 1 month of treatment.

*Treatment of patients
pneumonia

Should not be used if


patient is allergic to it, or
have liver disease,
gallbladder disease,
severe kidney disease, or
patient is on dialysis.

dinner 8pm
Vitamins, Food
supplement

Vitamin K
(AquaMEPHYT
ON)
10mg IV OD
10pm
Vitamins

active hepatitis.
2.Liver cirrhosis.
3.Drug-induced
hepatitis.
4.Alcoholic liver disease.
5.Fatty change of the
liver. 6.Autoimmune
hepatitis.
Silymarin, protects the
liver from damage and
enhances its
detoxification processes
by acting as an
antioxidant, increases
the intracellular level of
superoxide dismutase
and bile flow (a
choleretic effect ),
inhibits the formation of
leukotrienes, stimulate
hepatocyte
regeneration.
An antihemorrhagic
actor that promotes
hepatic formation of
active prothrombin.
*for the treatment of
the patients prolonged
prothrombin time

None known.

Dizziness, transient hypotension


after IV administration, rapid and
weak pulse,
diaphoresis,flushing, erythema,
pain, swelling and hematoma at
injection site.

Monitor PT to determine dosage


effectiveness as ordered.
Assess skin for ecchymoses, petechiae.
Assess gums for gingival bleeding,
erythema.
Assess urine for hematuria.
Assess Hct, platelet count, urine/stool
culture
for occult blood. Assess for decrease
in B/P, increase in pulse rate,
complaint of
abdominal/back pain, severe headache
(may be evidence of hemorrhage).
Assess peripheral pulses.
Check for excessive bleeding from

Prednisone
20, 10, 5
1 tab OD 8am
Glucocorticoid

Inhibits accumulation of
inflammatory cells at
inflammation sites,
phagocytosis, lysosomal
enzyme
release/synthesis,
release of mediators of
inflammation.

Acute superficial herpes


simplex keratitis,
systemic fungal
infections, varicella,
administration of live or
attenuated virus vaccines.

Fortifier-FA
(Ferrous
fumarate)
1 tab OD 8am
Hematinic

Essential component in
formation of Hgb,
myoglobin, enzymes.
Promotes effective
erythropoiesis and
transport, utilization of
oxygen.

Hemochromatosis,
hemolytic
anemias.

Folart (folic
acid)
5 mg 1 cap OD
8am
Nutritional
supplement

Stimulates production of
platelets, RBCs, WBCs.

None known

Cyanocobala
min
(Vitamin

USES
Treatment of
megaloblastic and
macrocytic
anemias due to folate
deficiency.
*for patients anemia
Coenzyme for metabolic
functions (fat,
carbohydrate

Contraindications:
Hereditary optic nerve
atrophy, history of allergy

Endocrine: Hirsutism
(occasional), adverse effects on
growth and development of the
individual and on sperm.
Body as a Whole: Sensitivity to
heat; fat embolism, hypotension
and shock-like reactions.
CNS: Insomnia
GI: Gastric irritation or ulceration.
Skin: Ecchymotic skin lesions;
vasomotor symptoms. Also see
prednisone.
Large doses may aggravate
existing GI
tract disease (peptic ulcer,
regional enteritis, ulcerative
colitis).
Severe iron poisoning occurs most
often in children, manifested as
vomiting, severe abdominal pain,
diarrhea, dehydration, followed by
hyperventilation, pallor, cyanosis,
cardiovascular collapse.
Allergic hypersensitivity occurs
rarely
with parenteral form. Oral folic
acid is
nontoxic.

Impurities in preparation may


cause rare
allergic reaction. Peripheral

minor cuts, scratches.


Give with meals to reduce gastric
irritation.
Monitor B/P, serum electrolytes,
glucose,
results of bone mineral density test,
height, weight in children. Be alert to
infection (sore throat, fever, vague
symptoms); assess oral cavity daily for
signs of candida infection (white
patches, painful
tongue/mucous membranes).
Monitor serum iron, total iron-binding
capacity, reticulocyte count, Hgb,
ferritin.
Monitor daily pattern of bowel activity,
stool consistency.
Assess for clinical improvement,
record relief of iron deficiency
symptoms (fatigue, irritability, pallor,
paresthesia of extremities, headache).
Tell patient to expect stool color to
darken.
Assess for therapeutic improvement:
improved sense of well-being, relief
from
iron deficiency symptoms (fatigue,
shortness
of breath, sore tongue, headache,
pallor).
PATIENT/FAMILY TEACHING
Eat foods rich in folic acid, including
Fruits, vegetables, organ meats.
Assess for CHF, pulmonary edema,
hypokalemia in cardiac pts receiving
subcutaneous/ IM therapy.

B12)
0.6 ml/IM OD
10am
Vitamin, Anti
anemic

metabolism, protein
synthesis).
Therapeutic Effect:
Necessary for cell
growth and replication,
hematopoiesis,
myelin synthesis.

to cobalamins.
Cautions: Folic acid
deficiency, anemia,
premature neonates.

vascular
thrombosis, pulmonary edema,
hypokalemia,
CHF occur rarely.

Monitor serum potassium (3.55


mEq/L), serum B12 (200800 mcg/ml),
rise in reticulocyte count (peaks in 58
days). Assess for reversal of deficiency
symptoms (hyporeflexia, loss of
positional sense, ataxia,
fatigue, irritability, insomnia, anorexia,
pallor, palpitations on exertion).
Therapeutic response to treatment
usually dramatic within 48 hrs.

Pregnancy, abnormal
genital bleeding of
unknown etiology,
lactation.
Porphyria.
Renal or cardiac oedema.
Thromboembolic
disorders.
Allergic reaction to Nacetylcysteine.
Active peptic ulcer

Markedly impaired hepatic, renal


or cardiac function; porphyria;
thromboembolic disease;
androgen dependent tumor;
abnormal vaginal bleeding and
breast disease that have not been
fully investigated.

Take this medicine with food to


decrease stomach upset.
Take your doses at regular intervals.
Do not take your medicine more often
than directed.

Hypotension, disturbances of liver


function, acidosis, convulsion,
cardiac and repiratory arrest

Should be taken with food.


Inform your physician about any
previous history of rush or
bronchospasm due to treatment with
N-acetyl cysteine.
Do not uses with antitussive medicines
since the suppress the cough reflex

USES
Treatment of pernicious
anemia, vitamin
B12 deficiency due to
malabsorption diseases,
increased B12
requirement due to
pregnancy,
thyrotoxicosis,
hemorrhage,
malignancy,
hepatic/renal disease.
*for patients anemia
Ladogal
(danazol)
200mg 1cap
OD 10am
Synthetic
steroid
hormone

For the treatment of


endometriosis, benign
breast disease and
hereditary angioedema.

Exflem
(Acetylcystei
ne)
600mg
1tab+50cc
H2O q12
Mucolytic

The thiol group of Nacetylcysteine breaks


up the disulfide bonds
of the viscous bronchial
secretions affording
smaller molecules with
lower viscosity which

are cleared by
coughing. This results in
clearing of respiratory
ducts and facilitates
breathing.

and the physiologic self-cleaning


mechanism of respiratory airways,
thus causing mucus stasis in bronchial
ducts will increase the risk of
infection , occurrence of
bronchospasm.
Special attention must be paid to
patients with bronchial asthma
because of the risk of bronchospasm in
these patients.
Patients with gastrointestinal bleeding
must use this medicine with caution
since it increases nausea.

Paracetamol
500mg 1tab
RTC q4
Antipyretic

Iterax
(Hydroxyzine)
25mg 1tab OD
9pm
Sedative

Decreases fever by
inhibiting the effects of
pyrogens on the
hypothalamus heat
regulating centers & by
a hypothalamic action
leading to sweating &
vasodilatation.

competes with
histamine for H 1receptor sites
on effector cells in the
GIT, blood vessels and
respiratory tract

Hypersensitivity,
intolerance to tartrazine
(yellow dye #5), alcohol,
table sugar, saccharin,
Contraindicated with
allergy to acetaminophen

Hypersensitivity to the
drug

Stimulation, drowsiness, nausea,


vomiting, abdominal pain,
hepatotoxicity, hepatic
seizure(overdose, Renal
failure(high, prolonged doses),
leucopenia, neutropenia,
hemolytic anemia (long term use)
thrombocytopenia, pancytopenia,
rash, urticaria, hypersensitivity,
cyanosis, anemia, jaundice, CNS,
stimulation, delirium followed by
vascular collapse, convulsions,
coma, death.

Assess patients fever or pain: type of


pain, location, intensity, duration,
temperature, and diaphoresis.

CNS: drowsiness, agitation,


ataxia, dizziness, headache,
weakness
Resp: wheezing
GI: dry mouth, bitter taste,
constipation, nausea
Derm: flushing

Assess motor responses


(agitation, trembling, tension),
autonomic responses (cold/clammy
hands,
diaphoresis).

Assess allergic reactions: rash,


urticaria; if these occur, drug may have
to be discontinued.
Teach patient to recognize signs of
chronic overdose: bleeding, bruising,
malaise, fever, sore throat.
Tell patient to notify prescriber for pain/
fever lasting for more than 3 days.

Others: chest tightness, urinary


retention
Ursofalk
(Ursodeoxycho
lic acid)
250mg 1cap
BID
Cholelitholytics
& hepatic
protectors

Action:
Suppress hepatic
synthesis, biliary
secretion and intestinal
reabsorbing of
cholesterol.

Lactulose
(duphalac)
30cc q12
Ammonia
detoxicant

Prevents reabsorption of
ammonia, producing
osmotic effect.

Uses:
-for the treatment of a
condition where the bile
ducts in the liver
become damaged
leading to a build-up of
bile. This may cause
scarring of the liver. The
liver should not be so
damaged that it is not
functioning properly.
This condition is called
primary biliary cirrhosis
(PBC).
-to dissolve gallstones
caused by excess
cholesterol in the gall
bladder. The gall
bladder should still be
working despite the
gallstone(s).

Therapeutic Effect:
Promotes increased
peristalsis, bowel
evacuation; decreases

-Hypersensitivity to bile
acids (like
ursodeoxycholic acid) or
to any of the other
ingredients of Ursofalk
capsules.
-Acute inflammation of
the gallbladder or biliary
tract.
-Obstruction of the biliary
tract.
- Frequent cramp-like
upper abdominal pain
(biliary colic).
- calcified gallstones.
- impaired contractility of
the gall bladder

CNS: anxiety, fatigue, depression


CV: chest pain, hypertension,
peripheral edema, gallstone
calcification
GI: diarrhea

Administer with food intake.


Monitor the liver parameters of AST
(SGOT), ALT (SGPT), and GGT every 4
weeks, for the first three months of
therapy.

Contraindications: Use in
pts requiring a lowgalactose diet.

Diarrhea indicates overdose.


Long-term
use may result in laxative
dependence,
chronic constipation, loss of
normal
bowel function.

Assess condition before therapy and


reassess regularly thereafter to
monitor drugs effectiveness.
Monitor pt for any adverse GI
reactions, nausea, vomiting, diarrhea
Assess for adverse reactions
for pt. with hepatic encephalopathy:
regularly assess mental condition

serum ammonia
concentration.
Aminoleban
IV infusion 500
cc x 6hrs
q12hrs
Amino acid

Aminoleban
1 sachet 50g
with a glass of
water BID
6am-8pm
Dietary
supplement

Propranolol
(Inderal)

Aminoleban normalized
the pattern of free
amino acids in the
plasma and brain,
improved serotonin
metabolism in the brain
and corrected a sleepwakefulness pattern in a
rat model of chronic
hepatic insufficiency
which underwent a
portacaval shunt
operation.
Indication:
Treatment of hepatic
encephalopathy in
patient with chronic
liver disease
Given to normalize the
amino acid,
carbohydrate, fats,
vitamins and minerals in
the plasma.
Indication:
Dietary supplement
especially with patients
with liver impairments.
For the treatment of
hepatic encephalopathy
in patient with chronic
liver disease
Blocks beta1-, beta2adrenergic receptors.

Severe renal disorder;


abnormal amino acid
metabolism

Hypoglycemia, hyperammonemia.
Acidosis may occur when large
dose are administered rapidly.
Hypersensitivity: rare skin
eruptions
GI: occasional nausea and
vomiting, diarrhea
Others: Occasional chills, fever
and headache

Severe renal disorder;


abnormal amino acid
metabolism

Hypersensitivity: rare skin


eruptions
GI: occasional nausea and
vomiting, diarrhea
Others: Occasional chills, fever
and headache

Asthma, bradycardia,
cardiogenic shock, COPD,

Allergic
reactions: Pharyngitis, erythema

Monitor I & O
Monitor for increase glucose level in
diabetic pts
Assess patients condition before
starting the therapy.
Monitor patient for hypoglycemia.
Be alert to adverse reactions.
Monitor patients temperature.
If GI reaction occurs monitor patients
hydration.

Take with food.


Monitor patients temperature.
Be alert to adverse reactions.
If GI reaction occurs monitor patients
hydration.

Give oral drug with food to facilitate

10mg 1tab BID


For portal hypertention
Antihypertensi
ve

Quinogen
500mg 1/2tab
BID

Used in the systemic


treatment of infections.

heart block greater than


first-degree (unless pt has
functional pacemaker),
Raynauds syndrome,
uncompensated CHF.
Use cautiously with
hypoglycemia and
diabetes, thyrotoxicosis,
hepatic dysfunction.

Hypersensitivity to
ciprofloxacin and other
quinolones

tous rash, fever, sore


throat, laryngospasm,
respiratory distress
CNS: Dizziness, vertigo,
tinnitus, fatigue, emotional
depression, sleep disturbances,
hallucinations, disorientation,
memory loss, slurred speech
CV: Bradycardia, CHF, cardiac
arrhythmias, sinoatrial or AV nodal
block, peripheral vascular
insufficiency, claudication, CVA,
pulmonary edema, hypotension
Dermatologic: Rash, pruritus,
sweating, dry skin
GI: Gastric pain, flatulence,
constipation, diarrhea, nausea,
vomiting, anorexia,
fibrosis, hepatomegaly,
acute pancreatitis
GU: Impotence, decreased
libido, Peyronie's disease, dysuria,
nocturia, frequency
Musculoskeletal: Joint
pain, arthralgia, muscle cramp
Respiratory: Bronchospasm, d
yspnea, cough, bronchial
obstruction, nasal stuffiness,
rhinitis, pharyngitis
Other: Decreased exercise
tolerance, development
of ANAs, hyperglycemia or
hypoglycemia, elevated
serum transaminase,
alkaline phosphatase, and LDH.
Nausea, diarrhea, CNS
disturbance local IV site reactions,
abnormalities of liver associated

absorption.

Do not discontinue the medication


abruptly; abrupt discontinuation can
cause a worsening of your disorder.

If you have diabetes, the normal signs


of hypoglycemia (tachycardia) may be
blocked by this drug; monitor your
blood or urine glucose carefully; eat
regular meals, and take your diabetic
medication regularly.

You may experience these side effects:


Dizziness, drowsiness, lightheadedness, blurred vision (avoid
driving or performing hazardous tasks);
nausea, loss of appetite (eat frequent
small meals); nightmares,
depression (request change of your
medication); sexual impotence.
Report difficulty breathing, night
cough, swelling of extremities, slow
pulse, confusion, depression, rash,
fever, sore throat.

Give drug as ordered by the physician.


Assess for adverse effects.

Anti-infective
Aminomix
1amp in 1L
PNSS x 3
cycles
Amino acids,
multivitamins.

NovoMix 30
FlexPen
18 units SQ
before
breakfast
14 units SQ
before dinner
insulin aspart ;
rapid-acting
and an
intermediateacting effect,

It can enhance amino


acid effects and transfer
assimilated protein to
essential protein in the
human body to promote
growth, appetite, adding
weights and effectively
balancing blockers of
body because of the
combination of
multivitamins with
amino acids.
Indications:
Nutritional supplement
for convalescence
patients, lactating
women, infants, childn
& for patients w/ acute
& chronic liver disease
eg liver cirrhosis, fatty
liver & hepatic
encephalopathy.
The blood glucose
lowering effect of insulin
occurs when the
molecules facilitate the
uptake of glucose by
binding to insulin
receptors on muscle
and fat cells and
simultaneously inhibit
the output of glucose
from the liver.
Use:

Hypersensitivity to any
ingredients of Aminomix.

Hypersensitivity to
biphasic insulin as part or
to any of the excipients of
NovoMix 30 FlexPen.
Hypoglycemia

enzymes (hepatic enzymes),


headache, restlessness, and rash.
Severe allergic reactions (rash;
hives; itching; difficulty breathing;
tightness in the chest; swelling of
the mouth, face, lips, or tongue).

Hypoglycemia, in general is the


most frequently occurring adverse
effect.
It may occur if the insulin dose is
too high in relation to the insulin
requirement and therefore require
special attention during dose
intesification.
Immune System Disorders:
Uncommon: Urticaria, rash,
eruptions.
Very Rare: Anaphylactic reactions.
Symptoms of generalized

For diabetes patients - Some brands of


amino acid-based nutritional
supplement may affect blood sugar.
Check blood sugar levels closely.

Administer immediately before or soon


after a meal.
Examination of injection sites for
lipodystrophy (lumpy areas).

in the ratio
30/70
Antidiabetics

used to treat diabetes


mellitus in adults,
adolescents and
children aged 10 years
and above
*Treatment of DM.

Mitodex
2 vials in D5W
8hrs OD x 3
cycles
Hepatic
protectors

Treatment of
mitochondrial
dysfunctions. Acute and
chronic hepatitis, fatty
liver, hepatic cirrhosis,
hepatic intoxication by
drug or chemical
substances.
Contains Vitamin B and
amino acids; Used in
liver therapy

Patients with history of


hypersensitivity to any
components of the drug

hypersensitivity may include


generalized skin rash, itching,
sweating, gastrointestinal upset,
angioneurotic edema, difficulties
in breathing, palpitation and
reduction in blood pressure.
Generalized hypersensitivity
reactions are potentially lifethreatening.
Nervous System Disorders: Rare:
Peripheral neuropathy. Fast
improvement in blood glucose
control may be associated with a
condition termed acute painful
neuropathy, which is usually
reversible.
Eye Disorders: Uncommon:
Refraction disorder. Refraction
anomalies may occur upon
initiation of insulin therapy. These
symptoms are usually of
transitory nature.
CNS: rarely - a state of arousal.
Cardiovascular system: rarely pain in the heart, tachycardia.
Allergic reactions: rarely urticaria.

Long-term use of large dosage of


pyrodxine is associated with the
development of servere peripheral
neuropathies.
Administration of doses >10 mcg of
cyanocobalamin daily may produce a
hematological response in patients
with folate deficiency; indiscriminate
use may mask the precise diagnosis.
Follow recommended dosage and
administration method.
If there is any specific symptom
following administration, discontinue
usage and physician must be
consulted.
If there is no improvement after a

Cefixime
Antibiotic

Ipravent UDV
(Ipratropium
Bromide)
Bronchodilator

Treatment of susceptible
infections due to S.
pneumoniae, S.
pyogenes, M.
catarrhalis, H.
influenzae, N.
gonorrhoeae,
E. coli, P. mirabilis
including otitis media,
acute bronchitis, acute
exacerbations of
chronic bronchitis,
pharyngitis, tonsillitis,
uncomplicated UTI,
uncomplicated
gonorrhea.
*for patient pneumonia
Open and widen the
airways, inhibits nasal
secretions.
*to loosen secretions in
the lungs of the patient

Dulcolax
2 tab
Laxative

Expands intestinal fluid


volume by increasing
epithelial permeability.
*for patients
constipation

History of
hypersensitivity/
anaphylactic reaction to
cephalosporins.

Antibiotic-associated colitis, other


superinfections
(abdominal cramps, severe
watery diarrhea, fever) may result
from
altered bacterial balance.
Nephrotoxicity
may occur, esp. in pts with
preexisting
renal disease. Pts with a history of
allergies,
esp. to penicillin, are at increased
risk for developing a severe
hypersensitivity
reaction (severe pruritus,
angioedema,
bronchospasm, anaphylaxis).

Hypersensitivity to
atropine, narrow angle
glaucoma, and
obstruction in the
gastrointestinal tract and
urinary system.

History of hypersensitivity
to atropine.
Cautions: Narrow-angle
glaucoma, prostatic hypertrophy,
bladder
neck obstruction, myasthenia
gravis.

Acute surgical abdomen,


nausea, vomiting,
abdominal cramps,
intestinal obstruction,
fecal impaction; use of
rectal suppository in

Abdominal pain and diarrhea.


Following episodes may
occur: Immune System
Disorders: Anaphylactic reactions,
angioedema, hypersensitivity.
Metabolism and Nutrition

month of treatment, physician must


also be consulted.
Assess oral cavity for white patches on
mucous membranes, tongue (thrush).
Monitor daily pattern of bowel activity,
stool consistency. Mild GI effects may
be
tolerable (increasing severity may
indicate
onset of antibiotic-associated colitis).
Monitor renal function tests for
evidence
of nephrotoxicity.

Monitor rate, depth, rhythm, type of


respiration;
quality, rate of pulse.
Assess lung sounds for rhonchi,
wheezing, rales.
Monitor ABGs.
Observe lips, fingernails
for cyanosis (blue or dusky color in
light-skinned pts; gray in dark-skinned
pts).
Observe for retractions (clavicular,
sternal, intercostal), hand tremor.
Evaluate periodically patients need for
continued use of drug; bisacodyl
usually produces 1 or 2 soft formed
stools daily.
Add high-fiber foods slowly to regular
diet to avoid gas and diarrhea.

presence of anal or rectal


fissures, ulcerated
hemorrhoids, proctitis.

D5050
Carbohydrate,
hypertonic
solution
Merozan
Antibiotic

KCl 20 mEq

+ D5W 90cc
4hrs for 3
cycles
Potassium
replenisher

Used in emergency care


to
treat hypoglycemia and
to manage coma of
unknown origin.
Treatment of infections
caused by susceptible
strains of
microorganisms

No significant
contraindications.

Treatment and
prevention of
hypokalemia.

Should be given with


caution with patient with
kidney impairment,
hyperkalemia, heart
conditions, dehydration
and burns

*to increase potassium


of the patient

Hypersensitivity to
meropenem,
carbapenems, penicillins
or other -lactam
antibiotics.

Disorders: Dehydration.
Nervous System
Disorders: Dizziness, syncope.
Dizziness and syncope occurring
after taking bisacodyl appear to
be consistent with a vasovagal
response (eg, abdominal spasm,
defecation).
Gastrointestinal
Disorders: Abdominal cramps and
pain, diarrhea, nausea,
hematochezia (blood in stool),
vomiting, abdominal discomfort,
anorectal discomfort, colitis.
Warmth, pain, burning from
medication infusion,
thrombophlebitis, rhabdomyositis

Adequate fluid intake includes at least


68 glasses/day

Inflammation, thrombophlebitis,
pain at injection site; rash,
pruritus, urticaria; abdominal
pain, nausea, vomiting, diarrhea;
thrombocythemia, eosinophilia,
thrombocytopenia, leukopenia,
neutropenia, positiveve direct or
indirect Coombs' test, reduction in
thromboplastin time; increase
serum bilirubin, transaminases,
alkaline phosphatase & lactic
dehydrogenase; headache,
paresthesia; oral candidiasis.
Nausea, vomiting, diarrhea,
potassium intoxication which can
cause confusion, weakness and
arrhythmia

Overgrowth of nonsusceptible
organisms may occur. Not use for
methicillin-resistant staphylococci
infections. Consider diagnosis of
pseudomembranous colitis in patients
who develop diarrhea. Coadministration w/ potentially
nephrotoxic drugs. Pregnancy &
lactation. Infant <3 mth.

Check blood sugar level before giving.

Monitor serum potassium (particularly


in renal impairment).
If GI disturbance is noted, dilute
preparation further or give with meals.
Be alert to decreased urinary output
(may be indication of renal

Meropenem
Antibiotic

Lower respiratory tract


infections, febrile
neutropenia,
gynecologic/
obstetric infections,
sepsis, acute pulmonary
exacerbation in cystic
fibrosis, urinary tract
infections, meningitis
(adults), pneumonia.

Anaphylactic reaction
to other beta-lactams.

Antibiotic-associated colitis, other


superinfections (abdominal
cramps, severe watery diarrhea,
fever) may result from altered
bacterial balance. Anaphylactic
reactions.
Seizures may occur in those with
CNS disorders (e.g., brain lesions,
history of seizures), bacterial
meningitis, renal impairment.

Insuget R
IV
Regular insulin
Short acting

The major effects of


insulin on carbohydrate
homeostasis following
its binding to specific
cell-surface receptors
on insulin-sensitive
tissues, notably the
liver, muscles and
adipose tissue. It
inhibits hepatic glucose
production and
enhances peripheral
glucose disposal
thereby reducing bloodglucose concentration.

Hypoglycemia, patients in
coma due to
hyperglycemia.

Hypoglycemia, headache, nausea,


palpitation. Local & generalized
hypersensitivity reactions.

Antidiabetics

insufficiency).
Monitor daily pattern of bowel activity,
stool consistency.
Assess I&O diligently during diuresis, IV
site for extravasation, phlebitis.
Be alert to evidence of hyperkalemia
(skin pallor/coldness, complaints of
paresthesia, feeling of heaviness of
lower extremities).
Monitor daily pattern of bowel activity,
stool consistency. Monitor for nausea,
vomiting. Evaluate for inflammation at
IV
injection site. Assess skin for rash.
Evaluate
hydration status. Monitor I&O, renal/
hepatic function tests. Check mental
status;
be alert to tremors, possible seizures.
Assess temperature, B/P twice a
day, more often if necessary. Monitor
serum
electrolytes, esp. potassium.
Administer immediately before or soon
after a meal.

It also inhibits lipolysis


thereby preventing the
formation of ketone
bodies.
Use:
Treatment of type 1 & 2
DM & gestational
diabetes; emergency
management of diabetic
ketoacidosis
*to lower blood glucose
level

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