Pengenalan Preparat Hormon

Reproduksi Sintetis
Drh. Cynthia D. Gaina, MTropVSc
17 Maret 2015

 Hormone CIDR-B (Controlled internal drug release (CIDR)

CIDR (Progesterone)
CIDRs contain 1.9g of progesterone
In cattle, CIDR-Bs are often used with synchronization
protocols
Eazi-Breed CIDR helps to improve the effectiveness of
reproduction programs by tightening estrus
synchronization so groups of cows and heifers come into
heat and can be bred in a narrow window.
Groups of cows also can be synchronized to return to
estrus after insemination for potential rebreeding in a
desired time frame.

 hCG, chorionic gonadotropin (Chorulon,Intervet, Holland)

Chorulon can be used in the following fertility problems in domestic

animals:
- cases of repeated failure of conception in cows and heifers
- induction of ovulation in mares and bitches
- cases of cystic ovaries in cows and heifers
- anoestrus in mares and bitches
- delayed ovulation, prolonged pro-oestrus in bitches
- deficiency in libido in male dogs
http://www.msd-animal-health.co.uk/Products_Public/Chorulon/090_Product_Datasheet.aspx

Species

Indication
Repeated failure of conception

Cow, heifer

Cystic ovarian disease (anoestrus,

prolonged oestrus, nymphomania)
Enhancement of luteal function

Mare

Suboestrus (follicles > 2 cm in

diameter)

Induction of ovulation
Anoestrus

Dosage and administration

1500 iu- i.m. or i.v. at AI or mating

3000 iu - i.v.

1500 iu - i.m. 12 days after insemination or mating

1500 - 3000 iu - i.m. or i.v., repeat after 2 days if
necessary
1500-3000 iu - i.m. or i.v. 24 hours before AI or
mating
500 iu - i.m. or i.v. at first day of oestrus after
pretreatment with PMSG 20 iu/kg s.c. daily for 10
days.

Bitch
Delayed ovulation, prolonged prooestrus

Male dog

Deficiency in libido

100-800 iu / day i.m., repeating treatment until

vaginal bleeding disappears. Mate on behavioural
oestrus
100-500 iu - i.m. twice weekly for up to 6 weeks,
but if this is not possible then 100-500 iu i.m. 6-12
hours before mating may give a temporary effect

 (Juramate, synthetic prostaglandin)

 Cloprostenol is a synthetic prostaglandin analogue structurally

related to Prostaglandin F2 (PGF2).
It causes functional and morphological regression of the corpus
luteum in cattle.
This effect on the life span of the corpus luteum usually results in
estrus 2 - 5 five days after treatment, followed by ovulation with
normal fertility.
Juramate alone will not increase fertility.

 Cloprostenol (Estrumate Inter-Ag, Hamilton, NZ)

 Cloprostenol

 (Lutalyse TM, Pharmacia & Upjohn Company, Pfizer Inc.).

 Capriglandin

 Prostavet

 Fertagyl

 Fertagyl is a sterile solution containing 43 g/mL gonadorelin

(GnRH; equivalent to 50 g/mL gonadorelin diacetate tetrahydrate)
Endogenous gonadorelin is synthesized by and/or released from the
hypothalamus during various stages of the bovine estrous cycle
following appropriate neurogenic stimuli. It passes via the
hypophyseal portal vessels, to the anterior pituitary to effect the
release of gonadotropins.
Synthetic gonadorelin administered intramuscularly or intravenously
also causes the release of endogenous LH and FSH from the
anterior pituitary.

 Capritocin

 CAPRITOCIN Inj. adalah hormon reproduksi yang mengandung

oxytocin dalam bentuk larutan injeksi, bekerja dengan cara
merangsang kontraksi otot polos pada uterus dan kelenjar susu
CAPRITOCIN Inj. sangat baik untuk membantu proses kelahiran,
memperlancar dan meningkatkan produksi air susu serta
mempercepat penyembuhan kasus metritis dan retensio
secundinarum

 PMSG Intervet
the hormone is commonly used in concert with
progestogen to induce ovulation in livestock
prior to artificial insemination.