Heather E.

Machado
371 Serra Street . Stanford, CA 94305 . Cell: 503-701-6356 . hmachado@stanford.edu

Education
2010 present Ph.D in Biology, Stanford University
Advisor: Dr. Dmitri Petrov
Dissertation: Drosophila and the contribution of environmental heterogeneity to the
maintenance of genetic variation
2005 2007

M.S. in Biology, Portland State University

Advisor: Dr. Mitchell Cruzan
Thesis: Differential Gene Expression in Response to Drought in Piriqueta caroliniana
Morphotypes

2001 2005

B.S. in Biology, Portland State University

Academic honors: Cum Laude

Research Experience
2010 present Stanford University
Genomic sequencing and analysis of spatial and temporal Drosophila melanogaster and
D. simulans collections. Development of error estimation and correction methods for
pool-seq. Long haplotype sequencing for tracking rapid evolution.
2008 2010

Reed College
Comparative genomic hybridization of African cichlid species to measure the prevalence
of gene duplication across lineages. Development of methods to correct for bias in cross
species genomic hybridizations.

2005 2007

Portland State University

Gene expression measurement and analysis of drought response in a hybrid system of
plants. Microarray development.

Teaching Experience
2010 present Stanford, Evolution BIO143 (2010), Ecology and Evolution Lab BIO44Y (2012 2013),
Molecular Evolution BIO113 (2015).
2008

Colegio Saint Patrick, Argentina, Ecology and Evolution lectures for secondary-school
students.

2005 2007

Portland State University, Plant Physiology Lab 441L/541L (2007), Principles of Biology
Lab 251L, 252L, 253L (2005- 2007), Guest lecture, Parapsychology, The Scientific
Method (2006).

Fellowships and Awards

2010 present Morrison Fellowship, Morrison Institute, Stanford University
Academic fellowship for graduate study.
2008

Student Fulbright Fellowship, US Department of State

A research fellowship with emphasis on cultural exchange.

2001-2005

Diversity Achievement Scholarship, Portland State University

Academic scholarship for undergraduate tuition.

Manuscripts
v

Machado, H.E., Pollen, A.A., Hofmann, H.A., and Renn, S.C.P. (2009) Interspecific profiling of
gene expression informed by comparative genomic hybridization: A review and a novel approach
in African cichlid fishes. Integrative and Comparative Biology 49: 644-659.
Machado, H.E. and Cruzan, M.B. (2010) Intraspecific Variation in Gene Expression Under
Prolonged Drought in Piriqueta Hybrids and Their Parental Taxa. Plant Science 178: 5.
Renn, S.C.P., Machado, H.E., Jones A., Soneji, K., Kulathinal, R., Hofman, H.A. (2010) Using
comparative genomic hybridization to survey genomic sequence divergence across species: A
proof-of-concept from Drosophila. BMC Genomics 11: 271.
Machado, H.E., Renn, S.C.P. (2010) A critical assessment of cross-species detection of gene
duplicates using comparative genomic hybridization, BMC Genomics 11: 304.
Machado, H.E., Jui, G., Joyce, D.A., Reilly, C.R., Lunt, D.H., Renn, S.C.P. (2014). Gene
duplication in an African cichlid adaptive radiation. BMC Genomics 15: 161.
Machado, H.E., Bergland, A.O., O'Brien, K.R., Behrman, E.L., Schmidt, P.S., Petrov, D.A. (in
review). Comparative population genomics of latitudinal variation in D. simulans and D.
melanogaster.

Programming Skills
v

Fluent: R, Perl, Bash

Intermediate: MySQL, Python, Matlab