Escolar Documentos
Profissional Documentos
Cultura Documentos
AbstractAs the clinical application grows, there is a rapid technical development of 3-D ultrasound imaging. Compared with 2-D
ultrasound imaging, 3-D ultrasound imaging can provide improved
qualitative and quantitative information for various clinical applications. In this paper, we proposed a novel tracking method for
a freehand 3-D ultrasound imaging system with improved portability, reduced degree of freedom, and cost. We designed a sliding
track with a linear position sensor attached, and it transmitted
positional data via a wireless communication module based on
Bluetooth, resulting in a wireless spatial tracking modality. A traditional 2-D ultrasound probe fixed to the position sensor on the
sliding track was used to obtain real-time B-scans, and the positions of the B-scans were simultaneously acquired when moving
the probe along the track in a freehand manner. In the experiments, the proposed method was applied to ultrasound phantoms
and real human tissues. The results demonstrated that the new system outperformed a previously developed freehand system based
on a traditional six-degree-of-freedom spatial sensor in phantom
and in vivo studies, indicating its merit in clinical applications for
human tissues and organs.
Index TermsApplication system, one degree of freedom,
volume reconstruction, wireless spatial tracking, 3-D ultrasound.
I. INTRODUCTION
HREE dimensional ultrasound imaging technology has
attracted growing attentions and been well developed because of its significant advantages in illustrating entire tissues
and providing quantitative analysis. In comparison with conventional 2-D ultrasound images, a 3-D ultrasound image allows viewing of an arbitrarily orientated image plane within the
patient and provides volume measurement of organs or lesions.
In comparison with computerized tomography and magnetic
This article has been accepted for inclusion in a future issue of this journal. Content is final as presented, with the exception of pagination.
2
Fig. 1.
This article has been accepted for inclusion in a future issue of this journal. Content is final as presented, with the exception of pagination.
HUANG et al.: LINEAR TRACKING FOR 3-D MEDICAL ULTRASOUND IMAGING
s
Tp =
sin
cos sin
0
Fig. 2.
Xo
Yo
. (2)
Zo
cos cos
0
1 0 0
0 1 0
Ts =
0 0 1
0 0 0
px)
px
Cv (
(1)
Z (t)
(3)
This article has been accepted for inclusion in a future issue of this journal. Content is final as presented, with the exception of pagination.
4
Fig. 4.
Fig. 6.
Fig. 5. Temporal calibration results. (a) Real position and the position recorded
in the software. (b) Root-mean-square errors between the two data streams.
This article has been accepted for inclusion in a future issue of this journal. Content is final as presented, with the exception of pagination.
HUANG et al.: LINEAR TRACKING FOR 3-D MEDICAL ULTRASOUND IMAGING
Fig. 9.
Fig. 7.
the following:
C =
I V
k =0
k
Wk I V
P
n
,
Wk
Wk =
1
(dk + )2
(4)
k =0
Fig. 11.
E. Experimental Methods
To assess the accuracy of the proposed 3-D ultrasound imaging system, we first conducted phantom experiments. An ultrasound resolution phantom (Model 044, CIRS, Inc., Norfolk,
VA) was employed. The phantom contained a number of coplanar anechoic tubby cylindrical lesions with different lengths
and diameters. One of the longest cylinders was reconstructed,
as shown in Fig. 9.We scanned the phantom for ten runs and
obtained ten sets of volumetric data. With reference to the documented dimensions, the imaging errors could be quantitatively
measured. As illustrated in Fig. 9, the diameters in X- and
Y -directions, and the length in Z-direction could be measured
This article has been accepted for inclusion in a future issue of this journal. Content is final as presented, with the exception of pagination.
6
TABLE I
QUANTITATIVE MEASUREMENT RESULTS OF THE DIMENSIONS ILLUSTRATED IN FIG. 7 AND THE DISTANCE ILLUSTRATED IN FIG. 8
within the reconstructed volume. The mean and standard deviation (SD) of measurement errors were reported in the next
section.
In addition to the cylindrical targets, we also made use of the
smaller targets to evaluate the accuracies of distance measurement based on the volumes produced by our system. As shown
in Fig. 10, the distance between any of two adjacent targets
could be measured and compared with the documented value.
The measurement errors indicated the imaging accuracy of the
system.
Moreover, a fetus phantom (Model 068, CIRS, Inc., Norfolk,
VA) was employed in the phantom study. Because the imaging
depth of the linear probe was too short to observe the entire
fetus, it was scanned by the convex probe which was of low
center frequency and larger field of view. Its 3-D image could
be used to qualitatively validate our system.
In our in vivo experiment, a young male subject (25 years old)
was recruited. The subjects forearm was immersed in a water
tank and scanned by the linear probe, as illustrated in Fig. 11.
The reconstructed volume could demonstrate the performance
of the proposed system in real applications. In order to better
illustrate the usefulness of the proposed system, it was also
compared with a previously reported freehand system which
was equipped with a 6-DoF spatial sensor (miniBird, Model
500, Ascension, VT) [12] in the experiments.
III. RESULTS
Fig. 11 illustrates the process of data collection using the
proposed system. The subjects forearm immersed in a water
tank was scanned. In the experiments, the sampling rate for
image acquisition was 21 Hz, and that for collecting positional
data was 35 Hz. The region of interest of the B-scans was of
480 450 pixels for the linear probe, and 280 240 pixels
for the convex probe. The spatial calibration experiments were
conducted for ten runs. , , and were 0.03 0.01 , 0.06
0.03 , and 0.04 0.01 , respectively, and Xo, Yo, and Zo
were 4.32 0.13 cm, 8.85 0.09 cm, and 0.46 0.06 cm,
respectively. From the temporal calibration experiments, the
time delay of the positional data stream relative to the image
data stream was 188.0 2.2 ms.
Table I presents the quantitative measurement results using two freehand 3-D ultrasound systems with 1-DoF and
6-DoF position sensors, respectively. It can be obviously observed that the 1-DoF position sensor resulted in more accurate
Fig. 12. Reconstruction of a fetus phantom using (a) the proposed system and
(b) a 6-DoF freehand 3-D ultrasound system.
measurement results, indicating a significantly improved imaging performance in comparison with traditional 6-DoF sensors.
In another word, the imaging accuracy of the proposed system
was improved by 0.462.14%. For the proposed system, the
average error for the volume measurement of the cylindrical
lesion embedded in the resolution phantom was 1.06 1.46%
(mean SD).
Fig. 12 shows two typical 3-D images of the fetus phantom
using the proposed system and the 6-DoF system, respectively.
In Fig. 12(a), the volume data consisting of 280 240 720
voxels was reconstructed using 793 B-scans collected in two
sweeps, and the computation time was 251 s. The head, limbs,
and trunk of the fetus can be clearly observed. Although the
reconstructed surfaces were not as smooth as the real one, the
shape of each body part was almost identical to that of the
phantom according to a qualitative evaluation, indicating good
performance of the proposed system in 3-D ultrasound imaging.
In Fig. 12(b), the volume data was computed based on the raw Bscans and spatial data generated by the 6-DoF sensor. However,
the reconstruction errors appearing to be some distortions can
be obviously seen in the face, head, shoulder, and arm of the
fetus.
Fig. 13 illustrates two volumes reconstructed from a part of
the subjects forearm based on the proposed system and the
6-DoF system, respectively. In Fig. 13(a), there were totally 210
B-scans collected, and the volume reconstruction took 49.3 s.
The volume data consisted of 160 120 240 voxels. In comparison with Fig. 13(a), the volume shown in Fig. 13(b) appears
less smooth, which was due to the relatively large reconstruction
This article has been accepted for inclusion in a future issue of this journal. Content is final as presented, with the exception of pagination.
HUANG et al.: LINEAR TRACKING FOR 3-D MEDICAL ULTRASOUND IMAGING
Fig. 14. Qualitative comparison between a raw B-scan in (a) and a reconstructed slice in (b).
This article has been accepted for inclusion in a future issue of this journal. Content is final as presented, with the exception of pagination.
8
Zhao Yang received the B.E. degree in communication engineering from Hubei University, Wuhan,
China, in 2008. He joined the School of Electronic
and Information Engineering, South China University of Technology, Guangzhou, China, as a Masters student in 2009 and is currently working toward
the Ph.D. degree in machine learning and computer
vision.
Gang Wei was born in January 1963. He received the B.S. degree from Tsinghua University, Beijing, China, and the M.S. and Ph.D. degrees from South China University of Technology
(SCUT), Guangzhou, China, in 1984, 1987, and 1990,
respectively.
He was a visiting scholar with the University of
Southern California, Los Angeles, from June 1997
to June 1998. He is currently a Professor with the
School of Electronic and Information Engineering,
SCUT. He is a Committee Member of the National
Natural Science Foundation of China. His research interests include digital signal processing and communications.