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First Physiology Quiz 209

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[Year]

1. Negative feedback mechanisms are denoted as negative because


a. the error and response are in opposite directions
b. output always tend to reduce the controlled variable
c. they respond only to a decline in the controlled variable
d. Their sensors are inhibited by a rise in the controlled variable
2. Which of the following processes occurs passively?
a. movement of potassium from the extracellular to intracellular fluid
b. movement of calcium from extracellular to intracellular fluid
c. movement of sodium from intracellular fluid to extracellular fluid
d. Absorption of glucose in the gastrointestinal tract
3. The sodium potassium pump moves 3 Na + from inside cells to outside and 2K +
in the opposite direction. What would happen to cell volume if sodium potassium
pump is blocked?
a. increase
b. decrease
c. does not change
d. First decrease and then is restored to normal
4. A patient was given a drug that increased his heart rate. What is the possible
mechanism of action of this drug?
a. it blocks muscarinic cholinergic receptor
b. it activates muscarinic cholinergic receptors
c. it activates beta 2 adrenergic receptors
d. it blocks beta 1 adrenergic receptors
5. A patient has a disease known to affect motor nerves electrophysiological studies
revealed that the speed of conduction of impulses along his motor nerves is lower
than expected. How could the disease lead to this?
a. complete destruction of the nerves
b. edematous swelling of nerves
c. destruction of the myelin sheath
d. Reducing the number of cholinergic receptors on motor end plates
6. A 40 years old women presented to the outpatient department with muscle
weakness that becomes toward the evening. To make the diagnosis she was given a
drug which caused immediate improvement in her condition. She was diagnosed as
having myasthenia gravis. What is the possible action of the drug given to her?
a. it inactivates acetylcholine estrase
b. it increases the number of active cholinergic receptor at moor endpate
c. it bind to and inactivate cholinergic receptors at motor endplate
d. directly block ion channels at the motor endplate
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First Physiology Quiz 209

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[Year]

7. A professional weight lifter started his session by lifting 25 kg and he went on and lifted
50, 75 and enabled him increase his force four times?
a. changing initial length of his muscles
b. recruitment of motor units
c. increasing frequency of stimulation of muscles
d. increasing the activity of calcium pumps in the endoplasmic reticulum
8. A 6 years old boy was brought to OPD with watery diarrhea and nausea since last two
days on examination he was dehydrated, his temperature was 370C, pulse was 100 / min
and systemic examination was normal. His mother was advised to give his home made
solution of sugar and salt with lemon added to it. By which mechanism is the sugar and
salt solution absorbed by the intestinal cells?
a. simple diffusion
b. secondary active transport
c. Osmosis
d. primary active transport
9. Which of the following characteristics of biological membrane is most influenced by
its cholesterol content?
a.thickness
b.ion permeability
c.fluidity
d.hydrophobicity
10. The function of tropomyosin in skeletal muscle is to:
a- release calcium after initiating contraction
b- bind to myosin during contraction
c- cover up the binding site on actin filaments
d- develop strong bonding between actin and myosin
11.Which of the following would result from stimulation of the parasempathetic nervous
system ?
a- decreased rate of gastric empting
b- dilatation of the pupil
c- vasoconstriction
d- empting of the urinary bladder
12. In the following diagram, what process is responsible for the change in membrane
potential that occur from +35 millivolts to -70 millivolts
a- opening of Na+ inactivation gates
b- opening of Na+ activation gates and inactivation gates
c- closure of K+ gates
d- opening of K+ gates
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First Physiology Quiz 209

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[Year]

13. To which of the following ions is the membrane of resting cells most permeable ?
a- potassium
b- chloride
c- calcium
d- sodium
14. A diagnosed patient of asthema comes to the doctor with the complaints of difficulty
in breathing . The doctor should advice him a drug that :
a- stimulate alpha1 receptors
b- blocks alpha1 receptors
c- stimulate beta1 receptors
d- stimulate beta2 receptors
15. The plateau phase of the cardiac contractile cell action potential coincides with
the :
a- ST segment of the electrocardiogram
b- second heart sound
c- ventricular relaxation and filling
d- " a" wave in atrial pressure curve
16. During ventricular isovolumetric relaxation , the volume of blood in the atria is :
a- increasing
b- slowly decreasing
c- rapidly decreasing
d- unchanged
17. During atrial systole :
a- both semilunar valves and both AV valves are closed
b- both semilunar valves and both AV valves are open
c- both semilunar valves are closed and both AV valves are open
d- the bicuspid valve is open but the tricuspid valve is closed
18- Sympathetic stimulation increases heart rate by.
19- Intrinsic control of cardiac output depends on the
a. degree of sympathetic discharge to the heart
b.extent of ventricular filling
c.level of circulation epinephrine
d.concentration of local metabolites

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First Physiology Quiz 209

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[Year]

20- During physical exercise, myocardium increases its O2 supply mainly


through
a.doubling its O2 extraction
b.an increase in local histamine release
c.vasodilation of the coronary arterioles
d.decrease in sympathetic discharge to coronaries

21- A myocardial infarction damaged the SA node of a 51 years old male . The
heart of such a patient will have
a.increased rate due to other cardiac ectopic regions taking over
b.increased rate due to unregulated sympathetic activation
c.decreased rate as AV node rhythm will take over
d.stopped beating due to loss of SA node "pacemaker" function
22- A 12 years old child was diagnosed to have mitral stenosis . On auscultation
the examining doctor would hear
a.whistling systolic murmur
b.whistling diastolic murmur
c.swishy systolic murmur
d.swishy diastolic murmur
23- A 60 years old male is having left ventricular heart failure . This patient is
expected to have increased
a.cardiac output from right ventricle
b.left ventricular contractility
c.left ventricular stroke volume
d.left vntricular end-systolic volume
24- A patient was diagnosed to have complete left bundle branch block . His
ECG recording would show
a.prolonged PR interval
b.elevated ST segment
C.increased amplitude of T wave
D.prolonged duration of QRS complex

25- The only electrical connection between atria and ventricles is the
A.SA node
B.right bundle branch
c. AV node
D.left bundle branch

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