Escolar Documentos
Profissional Documentos
Cultura Documentos
Table of content
Page
2
Table of content------------------------------------------------------------------------------------I
List of abbreviation-------------------------------------------------------------------------------III
Abstract---------------------------------------------------------------------------------------------1
1. Introduction-------------------------------------------------------------------------------------2
1.1. Back ground---------------------------------------------------------------------------2
2. Statement of the problem---------------------------------------------------------------------3
3. Literature review-------------------------------------------------------------------------------4
4. Significance of the study-----------------------------------------------------------------------5
5. Objective of the study--------------------------------------------------------------------------6
5.1. General objectives--------------------------------------------------------------------6
5.2. Specific objectives--------------------------------------------------------------------6
6. Methodology--------------------------------------------------------------------------------------6
6.1
6.2
6.3
6.4
6.5
6.6
6.7
6.8
study area----------------------------------------------------------------------------6
study design------------------------------------------------------------------------6
study period-------------------------------------------------------------------------6
study population--------------------------------------------------------------------6
source population------------------------------------------------------------------6
sampling unit------------------------------------------------------------------------6
study unit-----------------------------------------------------------------------------7
study variable------------------------------------------------------------------------7
6.8.1. Independent variables-------------------------------------------------------7
6.8.2. Dependent variables---------------------------------------------------------7
9. Action plan------------------------------------------------------------------------------------------10
10. Budget proposal-----------------------------------------------------------------------------------11
11. Reference-------------------------------------------------------------------------------------------14
12. Annex------------------------------------------------------------------------------------------------16
12.1. Questionnaire----------------------------------------------------------------------------17
II
4
List of abbreviation
AEFI: Adverse effect following immunization
BCG; Bacillus calmette Guerin
BSC: Bachlore of science
DTP: diphtheriatetanuspertussis
EFY: Ethiopian fiscal year
EPI: Expanded program of immunization
FMOH: Federal Ministry of Health
GAVI: Global alliance Vaccine and Immunization
Heb: Hepatitis type b
Hib: Homophiles influenza type b
HSDP: Health sector development program
IMR: Infant mortality rate
MCH: Maternal and Child Health
MDG: millennium development goal
MPH: Master of Public Health
NGO: Non-governmental organization
NPW: Non pregnant women
OPV: Oral Polio Vaccine
PEI: Polio Eradication Initiative
PI: Principal Investigator
PW: Pregnant women
RED: Reaching every district
RHB: Regional health Bureau
SOS: Sustainable outreach service
TT: Tetanus toxoid Vaccine
UN: United Nations
UNICEF: United Nations children fund
URTI: upper respiratory tract infection
V.P.D: vaccine preventable diseases
WCBA: Women child bearing Age
WHO: world health organization
III
5
ABSTRACT
Introduction: Infant and under five mortality rates in Ethiopia is among the highest in
the world. About 472,000 children die each year before their fifth birth days. The highest
proportion for childhood deaths is due to Vaccine preventable diseases. EPI program
encompass multiple activities to be conducted by different bodies at different level of
organization and health sectors. EPI was started in Ethiopia in 1980 with the aim of
reducing morbidity and mortality of children and mothers from vaccine preventable
diseases. During the inception of EPI the objective was to increase immunization
coverage by 10 % annually but this target has not been realized even after two decades
because of factors such as poor health infrastructure, low number of trained manpower,
high turnover of staff and lack of donor funding.
Objective:
Expected result:
Budget summary: This proposal will require a total of 20,642.50 Ethiopian birr with
personnel cost of 12,600.00, equipment and supplies cost of 3,460.00, transportation
and communication cost of 480.00, training /Refreshments cost of 1,410.00, and
contingency (10%) of 2,692.50.
1. Introduction
1.1. Back ground
Infant immunization is considered essential for improving infant and child survival. In
1974 when the world health organization (WHO) launched the Expanded program of
immunization (EPI), the program was based on the belief that most countries already
had some elements of nation immunization activities which could be successfully
expanded if the program become a national priority with the commitment from the
government to provide managerial manpower and fund to provide service to at least
85% of the target population .i.e. children under four years. Because of differences in
epidemiological factors the common childhood diseases targeted for vaccination in
Expanded Program on Immunization (EPI) are vary in different countries around the
world. WHO recommended targeted diseases, and also adopted in Ethiopia are
measles, pertussis (whooping cough), tuberculosis, tetanus, poliomyelitis and
diphtheria. (1)
Recently Hepatitis B virus and Homophiles Influenza type b are included in EPI
program in Ethiopia. (2)
EPI was started in Ethiopia in 1980 with the aim of reducing morbidity and mortality of
children and mothers from vaccine preventable diseases. During the inception of EPI
the objective was to increase immunization coverage by 10 % annually but this target
has not been realized even after two decades because of factors such as poor health
infrastructure, low number of trained manpower, high turnover of staff and lack of donor
funding. The same factors still affect the program today. The target group when the
program started were children under two years of age until it changed to one year in
1986 to be in line with the global immunization target. (3, 4)
Ethiopia has developed a health policy in 1993 and revised EPI policy in 1997. The
national EPI policy recommends that health workers should use every opportunity to
immunize eligible children according to the recommended schedule. The policy says
children who are hospitalized should be immunized as soon as their general condition
improve and at least before discharge from hospital. An individual with known or
asymptomatic HIV infection should receive all EPI vaccine at as early age as possible.
Patients with overt AIDS should receive all vaccine except BCG and yellow fever. EPI
service should be routinely available preferably on daily bases in all facilities
(Governmental, NGO and private).The policy also state about the need to screen and
assess status of children and women at every contact prior to giving antigens. The
program strategies of EPI are directed for increasing immunization coverage, to reduce
missed opportunities/ defaulters, increasing the quality of immunization service, improve
public awareness and community participation, to sustain high immunization coverage
and disease Eradication/control/Elimination strategies.
One of the strategy to combat vaccine preventable disease is immunization , 2001 EFY
national report showed that the immunization coverage of DPT3,measle and fully
7
under five mortality rate bout 140/1000 with variations among the regions from 114 to
233/1000 .This tragic fact places Ethiopia sixth among the countries of the world in
terms of the absolute number of child deaths. Among the cause of mortality, vaccine
preventable diseases are the major ones (2).
Every year more than 10 million children in low- middle-income countries die before
they reach their fifth birthdays. Most die because they do not access effective
interventions that would combat common and preventable childhood illnesses (3).
A 2001 vaccine-preventable diseases estimate of WHO showed that the greatest
burden of disease in Sub-Saharan Africa were deaths of pertussis, tetanus, and
measles which account 58 percent, 41 percent, 59 percent, and 80 percent respectively.
East Asia and the Pacific have the greatest burden from hepatitis B with 62 percent of
deaths worldwide. South Asia also experienced a high disease burden particularly for
tetanus and measles (11).In 2007, A total of 24.3 million infants not immunized DPT3,
from which Africa account 7.3%, South East Asian account 11.5% ,Europe account
0.4%, Western pacific and Eastern Mediterranean account 1.95 each and America
account 1.1% (12).
Ethiopia has an estimated population of approximately 76 million. Although infant
mortality rate (IMR) has declined from 97/1000 in 2000 to 77/1000 in 2005, it is still
among the highest in the world. From a total under five deaths in Ethiopia 28% is due to
pneumonia, 25% due to neonatal condition 20% each due to malaria and diarrhea, 4%
due to measles and the rest by other. Yet there is effective low cost intervention to
prevent two/third of these deaths of every 100 children in Ethiopia (14).
EPI is essential for improving infant and child survival although the coverage can be
improved by increasing KAP of the population.
In Debre Brehan town there are health facilities that give service to the community
including child vaccination. There are 1 hospital, 1 health center, 4 health post, 1
pharmacy, 1 higher clinic, 7 medium clinic, 8 low level clinic, 2 special clinic and 4 drug
store which are both governmental and non-governmental. According the 2002 annual
woreda health bereau report, the coverage of child vaccination is 56.3% BCG, 51%
Penta3, 57.7% Penta2, 51% OPV3, 41.5% measles. 43.9% of childrens are fully
immunized.
3. Literature review
A survey conducted in China about KAP towards Vaccine preventable disease the result
shows that the level of immunization knowledge among parents was positively
associated with attitude and practice of immunization. Immunization coverage was
89.3% in the high stratum in 63.8% in the low stratum service area (28).
In Africa, a serious 30 cluster immunization coverage survey was undertaken as a
survey of KAP among parents result of the survey showed 90% of population begins
immunization but 30% drop out. The survey conducted in Ethiopia and the weighted
national immunization coverage assessed by card plus history for children aged 12-23
months vaccinated before the age of one year was BCG 83.4%, DPT1 84.3%, DPT3
66.0% ,measles 54.3%, and fully immunized children 49.9% . A community based cross
sectional survey in Ziway town eastern showa shows 53% of children was fully
9
immunized, 19 % was defaulters and the rest were totally non-immunized. The reasons
for defaulters were inconvenience of vaccination time, child sickness and lack of
information about the need for repeated vaccination (30).
April 1995 in Gonder and surrounding villages in West Ethiopia cluster sampling was
conducted to assess immunization coverage in area and problem associated with
vaccination delivery. Among the sample children 47.4% fully immunized while 30% were
not immunized at all. The reason given for not immunizing children were lack of
knowledge 39.7% social problem 38.7% various obstacles 22% such as child sickness
and health institution related problems (31).
A cross sectional community based study was carried out in Jimma town South west
Ethiopia to determine reason for defaulting from expanded program of immunization
(EPI) using structured questionnaire in March 1997. A total of 376 children aged 12 to
23 months and their mothers were covered in study. Out of total 376 children 46.5%
were fully immunized, 53.5% were defaulters. The reason given by mothers for not
completing vaccination were missed appointments time (48.8%) mothers and no
enough time (25.9%) and child was sick (23.4%) maternal age, neonatal care , parity,
education knowledge about vaccine preventable disease and immunization. Another
study in Jimma town shows higher acceptance of immunization by mothers who have
been educated to above 6 grade and the higher of educational status the higher rate of
completing the vaccination schedule and the relation between occupation and child
immunization were government employee was the first to fully immunize their child that
is i.e. 94% and the least was house made that is 50% the reason for this might be
government employee could have access to know the benefit of immunization from their
passed education and daily activities but house maids might have lack of education &
economy. Also the study had been identified factors associated with non immunization
and defaulters was illiteracy, lack of knowledge about EPI target diseases attitude of
mothers were 45.6% said very useful, 54.1% said useful and the rest 0.3% said not
useful (32).
Currently a great consideration have given for immunization, the result have been under
expected. The aim of this study will be to assess the obstacles in relation to the mother
KAP to child immunization.
achieving effective immunization for all children are lack of awareness and lack of
knowledge. Miss information about immunization is amongst the most serious traits to
the success of immunization program. Some examples of rumors are: Vaccines are
contraceptives to population or to limit the size of certain ethnic group, Vaccines are
contaminated by HIV , and Children are ding after receiving vaccines.
The consequence of rumors can be serious and if not unchecked those can drawback
the EPI program (21).
This study helps to detect mothers KAP towards the eight types of vaccination, common
defects of mothers for not vaccinate their child. The result could be help to plan for child
immunization based health education to the community, and better practice among
mothers who have poor practice to immunize their children. In addition the study will
used as literature for others (individual, group, organization both governmental and nongovernmental) who wants to intervene based on the result obtained or who wants to do
further study to answer question that are not answered by this study.
practice of mothers towards child vaccination and its associated factors with child
vaccination in Debre Brehan district/ town.
Z 2 pq
=
d2
n = 384*2, with design effect of 2. By considering 5% non-response rat, the total sample
size will be 845. From the total 9 kebeles in the town 60%of them (5 kebeles) will be selected by
lottery method. From those kebeles households are selected proportionally until we meet the
total sample. The first house hold will be obtained by using sharp dot pencil with closed eye on
the sample frame. Every Kth house hold will be included in the sample. K is calculated by
dividing the total number of house hold by the sample house hold.
Kebele-1
Kebele-2
Kebele-3
Kebele-2
Kebele-4
Kebele-5
Kebele-4
Kebele-6
Kebele-6
Kebele-7
Kebele-8
Kebele-8
Kebele-9
13
Kebele-9
Household
version 6 and SPSS version 16 a statistically packed soft ware for analysis. Also the
data will be checked and cleaned for its completeness and errors in data entering. All
the data obtained from the study population will be entered, cleaned and analyzed by
the investigator. The result will be presented by using tables, charts, and graphs.
Qualitative data will be analyzed and presented by descriptive statement.
7. Dissemination of result
The result of the study will be disseminated to;
District health office.
Debre Brehan University research coordinating office.
Debre Brehan University, School of Health science.
Debre Brehan Save the children coordinating office.
Private clinic in the town.
8. Ethical consideration
This study will be conducted after the approval of the proposal by Debre Brehan
University research coordinating office. Primarily, ethical clearance will be obtained from
director of research coordinating office of Debre Brehan University. Formal letter of
cooperation will be written for District Health Office. Consent from District Health Office
will be obtained. The District Health Office will write cooperation letter to the town/district
administrator. The town/district administrator will write to the respective kebeles. The
data collectors will clearly introduce him/her self and explain the aims of the study.
Information will be collected after obtaining verbal consent from each participant.
Respondents will also be informed that they can refuse or discontinue participation at
any time they want and the chance to ask anything about the study. Information will be
recorded anonymously and confidentiality will be assured throughout the study period.
Data collectors will put their signature for they could obtain verbal consent for the
interview from the respondents. A woman who did not practice will be advised about the
benefits of immunization and for more information to communicate with health workers
in the district.
15
9. Action Plan
Time frame (2010)
No Major Activities
October
November
December
.
1.
Topic Selection
2.
Proposal Development
3.
Selection of data
4.
collectors
Training of data
5.
collectors
House numbering
6.
Conducting pretest
7.
Data collection
8.
9.
up
10. Submission of first draft
of the result
11. Submission of final
research paper.
12. Presentation of findings
N.B. For the above activities Debre Brehan University, Nursing Staffs are responsible.
Personnel Cost
Title
Qualification
Rate
Duration of
work
(DAYS)
Number of
persons
Total
Data collectors
BSCs above
100
10
7,000.00
Supervisors
MPH, BSC
200
2,800.00
MPH/statistician
150
600.00
MPH
250
2,000.00
Secretarial work
Diploma
100
200.00
SUB TOTAL 1
12,600.00
Equipment and supplies cost
Category
Unit
Quantity
Unit price
Questionnaire Printing
Page
2.00
10.00
Questionnaire
duplication
Page
4225
0.50
2,112.50
Page
80
2.00
160.00
page
480
0.50
240.00
Stapler
Number
60.00
60.00
Staples
Pack
15.00
30.00
Eraser
Number
1.50
7.50
Pen
Number
3.00
21.00
BIC
Pencils
Number
1.50
10.50
DOT
Binder
Number
20
140.00
Flash disk
Number
300.00
300.00
GENX-4GB
Number
6.00
18.00
Nature-720MGB
Bag
Number
70
350.00
17
SUB TOTAL 2
3,460.00
Transportation and communication cost
Category
Unit
Quantity
Unit price
Total
price
Remark
Transport
Trip
140
2.00
280.00
Minibus
Mobile-phone card
Card
50.00
200.00
SUB TOTAL 3
480.00
Others for training /Refreshments
Category
Unit
Number
of person
Number of
days
Unit price/price
per day
Total price
Food /launch
Individual
person
50.00 per
individual
700.00
Soft drink
Individual
person
5.00 per
individual
70.00
Tea break
Individual
person
10.00 per
individual
140.00
50 per
individual
500.00
SUB TOTAL
1,410
17,950.00
Contingency
2,692.50
GRAND TOTAL
20,642.50
Remark
11. Reference
1, M.K.JINADU, Lecturer, perspective in primary care: A case study in the Administration
of the expanded program of immunization in Nigeria, Journal of tropical pediatrics, 1983
29(217-219)
2. World Health Organization, United Nations Foundation, (2004). Immunization in
Practice Modules for Health Staff 2004 update, United Printers, Ethiopia
3. FMOH, EPI policy guideline, Ethiopia 2007.
4. http://www.who.int/countries/eth/areas/immunization/en/ (1 of 2) accessed in
19
8/25/2009 10:19:32 AM
5. FMOH, health and health related indicator, 999E.C (2006/7 G. c)
6. Expanded program of immunization, Ethiopia, November 8, 2008, accessed from
internet, in 26/8/2009
7. (FMOH, 2004). FMOH, Ethiopia Family Health Profile, 2003/4.
9, UNICEF, Immunization-expanding immunization coverage, accessed from internet in
Aug.25, 2009
10. FMOH, National strategy for child survival in Ethiopia, July 2005, AA, Ethiopia
11. Disease control priorities project Estimates of the Current Burden of Vaccinepreventable Diseases and of the Burden Averted by Vaccination, [http/www
.dcp2.org/disease/47,accessed on internet on Aug 30, 2009.)
12. WHO, progress towards global immunization goals-2007, summary presentation of
key indicators, updated September 2008, slide Global immunization, PDF
13, JW Lee. Child survival: a global health challenge. Lancet 2003; 362: 262- (Cross
reference:http://www.who.int/bulletin/volumes/85/6/06-031526/en/index.html#R1.)
14. WHO Vaccine preventable disease: monitoring system, 2006 global summary,
WHO/IVB/2006
15. WHO and FMOH, Enhancing Routine Immunization Service in Ethiopia: field guide
and essential tools for implementation, no date]-2
16. FMOH, National strategy for child survival in Ethiopia, July 2005, AA, Ethio8. FMOH,
EPI: Comprehensive multi-year plan 2006-2010, August 2006 Ethiopia.
17. FMOH, National strategy for child survival in Ethiopia, Ethiopian National health
policy, July 2005, AA, Ethiopia
18. Onta, Sabroe & Hansen, The quality of immunization data from routine primary
Health care reports: a case from Nepal. Health Policy Plan 1998, 13:131-139. Pub Med
Abstract] [Publisher Full Text
19. WHO Regional Office for Africa, Mid- Level Management Introductory Course for
EPI Managers) draft, March 2004
20. Expanded program on immunization, policy guideline, federal democratic republic of
Ethiopia minister of health revised in 2007
21. [Ethiop .J .Health Dev. 2008; 22(2):148-157]
22, kersa woreda health office yearly report 2001ec
23. Rahman MM; Esram MA; Mahalanab is D. Mother knowledge about vaccine
preventable disease and immunization coverage of population with high rate of illiteracy
journal of tropical pediatrics 1995 deci 41(6)376-8
24. Stratified K.SingarimbunM. Social factor affecting the use of child hood
immunization in yogyakata ,java ,Yogyakarta Indonesia ,Gadiah moda university
.population study center 1986 jun V.59
25. Gore prosannal ; Madhovan suresh, curry Duauld, MC clung gorden castiglia
20
12. Annex
12.1. Questionnaire
Consent form
My name is______________________ I am from Debre Brehan University, School of
Health Science, Program of Nursing. I am here on the behalf of Debre Brehan
University that conduct research in the community to collect data on assessment of
mothers practice to wards child vaccination and its associated factors with child
21
vaccination. The university gets permission from the district/ town health office and
kebeles administrator to conduct this research in your community. The objective of this
study is to assess mothers practice to wards child vaccination and its associated
factors with child vaccination at Debre Brehan town to provide useful information for
program managers and providers who enable them to improve the service provision.
You were selected for the study because you are in the study group. We are kindly
requesting you to answer the questions that we have prepared for you. Your information
is very useful to this study and it needs your patience, full cooperation and sincerity. All
information taken will be kept confidential. Only the data collector and principal
investigator access the information. You have the right not to participate in the interview
or to refuse at any stage of interviewing. There is no compensation that is given to you
after end of interview or observation.
Would you be willing to participate?
I agree
continue
I disagree
Stop
Respondent
Signature___________________
Date____________
Date_______________________
1. Single
2.Married
3. Divorced
4.Widowed
5. Religion
1. Muslim
2. Orthodox
specify_____________
3. Protestant
4. Other
6. Ethnicity
1. Tigre
2.Oromo
3.Amhara
4. Others (specify)
3. Grade 1-6
4. Grade 7-11
5. 12+
5.
2. 150-300
3. 300-600
4. 600-1000
5. > 1000
10. Who in the family make the decision to take the child for vaccination?
1. Mother
2. Father
(specify)___________
3. Both together
4. Other
2. No
3. If your answer is yes for Q NO 1, did the child complete vaccination according to the
schedule?
1. Yes /Fully immunized/
2. NO /Defaulter/
5. > Five
6.
6. Have you ever seen side effect of a vaccine while childrens have vaccinated?
23
1. Yes
2. No
3. Rash
2. No
2. No
2. Teared by children
3. Other
Immunization given
BCG
Polio
OPV0
BCG scare
OPV1
Pentavalent
OPV
2
OPV3
Present
DPT-HIBHBV1
DPT-HIBHBV2
Measles
DPT-HIBHBV3
Not Present
THANK YOU!
Name of Interviewer_______________________ Date______________
Sign_________
Name of
supervisor________________________Date______________Sign__________
24