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Acute Glomerulonephritis
Author: Malvinder S Parmar, MB, MS; Chief Editor: Vecihi Batuman, MD, FACP,
FASN more...
Overview
Presentation
DDx
Workup
Treatment
Medication
Updated: Jul 17, 2015
Background
Pathophysiology
Etiology
Epidemiology
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Patient Education
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Background
Acute glomerulonephritis (GN) comprises a specific set of renal diseases in which
an immunologic mechanism triggers inflammation and proliferation of glomerular
tissue that can result in damage to the basement membrane, mesangium, or
capillary endothelium. Acute poststreptococcal glomerulonephritis (PSGN) is the
archetype of acute GN. Acute nephritic syndrome is the most serious and potentially
devastating form of the various renal syndromes.
Hippocrates originally described the natural history of acute GN, writing of back pain
and hematuria followed by oliguria or anuria. Richard Bright described acute GN
clinically in 1827, which led to the eponymic designation Bright disease. With the
Acute Poststreptococcal
Poststreptococcal
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