Pathophysiology

Hypertension

Kidney release RENIN into the bloodstream

RENIN helps convert angiotensin I in liver

Angiotensin I is converted to angiotensin II ( a potent

vasoconstrictor) in lungs

Angiotensin II

Aldosterone: Cause NA and

water retension

Retained NA and Water

Increased Blood Volume

Arteriolar constriction Increased Peripheral vascular resistance

Increased Blood pressure and vascular resistance to hypertension