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Variola Virus
Disease Agent:
Variola virus
At-Risk Populations:
Vector/Reservoir Involved:
None
Blood Phase:
By the third or fourth day after infection, virusinfected macrophages enter regional lymph nodes
and possibly the blood stream. This is before prodromal symptoms develop at 7-17 days after infection.
Secondary viremia (which is also largely cell associated) occurs with the onset of symptoms.
Disease Name:
Unknown
Priority Level:
Background:
Cases/Frequency in Population:
Incubation Period:
TRANSFUSION
163S
APPENDIX 2
Mortality:
Chronic Carriage:
Treatment Available/Efficacious:
164S
TRANSFUSION
Suggested Reading:
1.
2.
3.
Unknown
Cellular tropism studies using primary hematolymphoid cells suggest some viral clearance by leukoreduction can be anticipated.
Leukoreduction Efficacy:
None
4.
5.
APPENDIX 2
6.
7.
8.
9.
TRANSFUSION
165S