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Drug Name

Date

Dose
Frequency/
Timing

Generic:
Hyoscine-Nbutylbromide

July 29, ,
2015

50 mg IVTT
every 8 hours

Brand
name:
Buscupan

Classification

*Antispasmodics

Mechanism of
Action

* It blocks the
muscarinic
receptors
found on the
smooth muscle
walls which
means its
blocks the
action of
acetylcholine
on the
receptors
found within
the smooth
muscle of the
gastrointestinal
and urinary
tract and thus
reduces the
spasms and
contractions.
This relaxes
the muscle and
thus reduced
the pain from
the cramps and
spasms..

Specific
Indications

Contraindication

Adverse Reactions

* Relief of
smooth muscle
spasm of the
gastrointestinal
and
genitourinary
systems.

*Contraindicated
Myasthenia
gravis,
megacolon,
hypersensitivity to
drug contents,
narrow angle
glaucoma,
prostate
hypertrophy with
urinary retention,
mechanical
stenosis in the GI
tract, tachycardia.

CNS:
drowsiness,dizziness,
confusion,restlessness,
fatigue,
CV:
tachycardia,palpitation,
hypotension.
GI: constipation,
drymouth,
GU: urinary hesitancy
or retention.
SKIN: decreased
sweating,rush

Nursing
Responsibility
Nursing
precaution
*Be alert for
adverse
reactions and
drug
interactions.
*Assess for eye
pain
*Assess for
urinary
hesitancy
*Assess for
constipation
*Monitor urine
output
*Encourage
patient to void.
*Monitor BP for
possible
hypertension
Nursing
precaution:
* Do not take
antacids and
antidiarrheal 2
to 3 hours prior
to raking this
drug.
*Avoid driving
or operating

machinery after
parenteral
dose.
*Use cautiously
to patients with
thyrotoxicosis,
cardiac
insufficiency,
pyrexia,
fructose
intolerance.

Drug Name

Date

Dose
Frequency/
Timing

Classification

Generic:
metoclopramid
e

July
29,2015

10 mg IVTT
every 8
hours

*Anti-emetic

Brand name:
Plasil

*Dopaminergic
blocker

Mechanism
of Action

*Stimulates
motility of
upper GI tract
without
stimulating
gastric,
billiary, or
pancreatic
secretions;
appears to
sensitize
tissues to
action of
acetylcholine;
relaxes
pyloric
sphincter,
which, when
combined
with effects
on motility,
accelerates
gastric
emptying and
intestinal

Specific
Indications

Contraindicatio
n

Adverse
Reactions

*Prophylaxis
of
postoperative
nausea and
vomiting.
*Also for
Short-term
therapy for
adults with
symptomatic
GERD who
fail to
respond to
conventional
therapy.

*Allergy to
metoclopramide.
* GI hemorrhage.
*Mechanical
obstruction or
perforation.
*Pheochromocytoma.
*Epilepsy

CNS:
*Restlessness,
drowsiness,
fatigue,
lassitude,
insomnia,
extrapyramidal
reactions,
parkinsonismlike reactions,
akathisia,
dystonia,
myoclonus,
dizziness,
anxiety
CV:
*Transient
hypertension
GI:
*Nausea,
diarrhea

Nursing
Responsibility
Nursing precaution
* Assess for other
contraindications.*Monitor
BP carefully .
*Monitor for
extrapyramidal reactions,
and consult physician if
they occur
*Educate patient about
side effects.
* Instruct to report
involuntary movement of
the face, eyes, or limbs,
severe depression,
severe diarrhea.
*Instruct patient to take
drug exactly as
prescribed.- *Instruct not
to use alcohol, sleep
remedies or sedatives;
serious sedation could
occur.

Nursing precaution:
*Use cautiously
With:

*lactation
*pregnancy
*fluid overload *renal
impairment

transit.

Drug Name

Generic:
omeprazole
Brand name:
Prilosec

Date

Dose
Frequency
/
Timing

July
29,201
5

40 mg
IVTT once
a day

Classification

*Antisecretory
drug
*Proton pump
inhibitor

Mechanism
of Action

*Suppresse
s gastric
acid
secretion by
specific
inhibition of
the
hydrogenpotassium
ATPase
enzyme
system at
the
secretory
surface of
the gastric
parietal
cells; blocks
the final
step of acid
production.

Specific
Indications

Contraindicatio
n

Adverse
Reactions

*Short-term
treatment of
active duodenal
ulcer;First-line
therapy in
treatment of
heartburn
orsymptoms of
gastroesophagea
l reflux disease
(GERD);

*Contraindicated
with
hypersensitivity
to omeprazole or
its components.

CNS:
: Headache,
dizziness,asthenia
, vertigo,
insomnia,apathy,
anxiety,
paresthesias,

*Short-term
treatment of
active benign
gastric ulcer;
*GERD, severe
erosive
esophagitis,
poorly
responsive
symptomatic

Dermatologic
:
Rash,inflammation
, urticaria,pruritus,
alopecia, dry skin
GI
: Diarrhea,
abdominal lpain,
nausea, vomiting,
constipation, dry
mouth,tongue
atrophy
Respiratory

Nursing
Responsibility
Nursing precaution
* Assess other
medications patient
maybe taking for
effectiveness and
interaction.
*Monitor therapeutic
effectiveness and
adverse reaction at the
beginning of therapy and
periodically throughout
the therapy.
*Assess GI system:
bowel sounds ,abdomen
for pain and swelling,
appetite loss.
*Monitor hepatic
enzymes.
*Assess
knowledge/teach

GERD;
*Long-term
therapy:
Treatment of
pathologic
hypersecretory
conditions
(Zollinger-Ellison
syndrome,
multiple
adenomas,
systemic
mastocytosis).

: URI
symptoms,
cough, epistaxis
Other
: Cancer in
preclinical studies,
back pain, fever

appropriate use of this


medication, interventions
to reduce side effects,
and other symptoms to
report.
Nursing precaution:
*Use cautiously
With:
-Hepatic impairment
-Pregnancy, lactation and
children less than 12
years old
*Presence of any alarms
symptoms(significant
unintentional weight loss,
recurrent vomiting,
dysphagia,
hematemesis, or
melena)should be taken
before meals and should
be swallowed whole.