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SID: ___________________________
Section: _________________________
INTRODUCTION TO GENETICS
LS4 Spring 2009
04/20/09
MIDTERM I
Please circle your TAs name:
EMILY
YI
BLAKE
EDDIE
RYAN
SATORU
Instructions:
1. This exam has 9 pages. Before starting, make sure you have all the pages.
2. Clearly write your name on every page. Be sure to write clearly. Only legible answers
will be graded.
3. Do not write on the backs of pages. We will not grade them.
4. All books, notes, and cell phones (turned off) must be put in zipped backpacks.
5. Calculators may be used. NO GRAPHING CALCULATORS ARE ALLOWED!
6. On the last page are the Critical Values for the Chi-Square Test.
Page 2
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Page 6
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Page 3
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Page 7
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Page 4
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Page 8
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Page 5
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Total:
_____________/100
Respond to the following questions and statements to the best of your ability.
Please note that you should limit your responses to the space provided. Points
will be taken off if you go beyond the limit and provide incorrect responses in the
presence of correct responses.
Name: _________________________________
(Last)
(First)
SID: ___________________________
Section: _________________________
A
.
B
.
C
.
D
.
E
.
F
.
G
.
H
.
I
.
A. Which one of the above represents Metaphase during Meiosis I? ___________
B. Which one of the above represents Metaphase during Mitosis? ____________
C. Which one of the above represents Metaphase during Meiosis II? _____________
Name: _________________________________
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(First)
SID: ___________________________
Section: _________________________
2. Lethal allele and Independent Assortment (12 points)
Heterozygous Cp cp chickens express a condition called creeper, in which the leg and wing
bones are shorter than normal (cp cp). The dominant Cp allele is lethal when
homozygous. Two alleles of an independently segregating gene determine white (W-)
versus yellow (ww) skin color. From mating between chickens heterozygous for both of
these genes, what phenotypic classes will be represented among the viable progeny, and
what are their expected relative frequencies?
Name: _________________________________
(Last)
(First)
SID: ___________________________
Section: _________________________
II
III
(A) What is the mode of inheritance of this RARE condition?
(B) If individuals II-2 and II-3 have three children, what is the probability that
exactly two of them will be affected? CIRCLE YOUR ANSWER.
Name: _________________________________
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SID: ___________________________
Section: _________________________
b) What phenotypic ratio of offspring would you expect if both the suppressor allele is
recessive and the mutant it suppresses is recessive, too? Show your work and CIRCLE
YOUR ANSWER.
Name: _________________________________
(Last)
(First)
SID: ___________________________
Section: _________________________
1
w
2
+
w
3
w
+
w
4
+
+
+
w
5
+
+
+
+
w
6
+
+
+
w
+
w
7
w
+
w
+
+
+
w
8
+
+
+
+
+
+
+
w
9
+
+
+
+
w
+
+
+
w
b) Explain why the phenotype of the F1 hybrids between mutants 1 and 2 differed from
that of the hybrids between mutants 1 and 3.
c) How many genes are represented by the mutations, and which mutations belong to each
gene?
Name: _________________________________
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(First)
SID: ___________________________
Section: _________________________
7.
analysis (12 points)
You are an undergrad working in a plant lab here at UCLA. The professor wants you to
determine if two genes responsible for flower color and flower blooming in Arabidopsis are
linked or unlinked. In the P generation, you cross a red-flowered, late-blooming plant with
a white-flowered, early-blooming plant. The resulting F1 (all red and late blooming) is
crossed with a white-flowered, early-blooming plant. You find:
403 red, late
395 white, early
143 red, early
151 white, late
If each of these traits is produced by a single gene, test if these two genes are
linked. Use chi-square analysis in your determination. Include in your answer:
your hypothesis in the 2 analysis, predicted values, 2 calculation, and your
conclusion. (Table on very last page)
Name: _________________________________
(Last)
(First)
SID: ___________________________
Section: _________________________