Review problems in Genetics

1.Based on the following crosses in sheep, determine the genotype of each individual.
Cross
Progeny
White-1 x White-2 6 white: 1 black
White-1 x White-3 5 white
White-1 x Black-1 3 white: 3 black
2.Blue diaper syndrome is a rare inborn error of human metabolism. Certain amino acids are not
absorbed in the small intestine and are excreted, causing a blue color in the feces.
a.If two normal individuals have an affected child, what is the mode of inheritance of the
disease?
b.what is the chance that the second child will be affected?
3. Two deaf individuals mate and produce three offspring who all can hear. If two of the offspring are
mated, what fraction of the progeny will be deaf?
4. Polydactyly and tongue curling are independent dominant traits in humans. A man has polydactyly
and his wife does not. Both can curl their tongues, but neither of their fathers could. What is the chance
of this couple having a child who is:
a. normal with a straight tongue?
b. polydactylic with a curling tongue?
5. Consider the following crosses in canaries:
Parents
Progeny
Yellow male x Yellow female 6 white: 1 black
Yellow female x Green male 5 white
Green female x Yellow male 3 white: 3 black
Explain these results by determining which allele is dominant and how color is inherited.
st

E. Problem Solving (60 points). Write your final answers in the 1 page of the answer sheet. Solutions
should be written (and properly labeled) at the back of the 2nd page of the answer sheet. When
necessary, round-off your answers up to three decimal places. Do not round-off at each step; rounding-off
should be done on the final answer.

1. A certain plant species has a diploid chromosome number of 24. How many chromosomes would be
expected in:
a. a microspore mother cell? (1 pt)
b. a leaf cell? (1 pt)
c. an endosperm cell? (1 pt)

2. Two individuals with the following genotypes are crossed. The four loci are found in different
chromosomes. There is complete dominance in A, N, and G loci and incomplete dominance in the O
locus.

Individual 1

Individual 2

AaNnggEELLOo

AaNnGgEELLOo

a. How many different types of gametes can individual 1 produce? (1 pt)

b. How many possible genotypes will there be in the progeny? (2 pts)
c. How many possible phenotypes will there be in the progeny? (2 pts)

3. A couple decides to have 6 children.

a. What is the probability that they will have four boys and 2 girls? (2 pts)
b. How many possible combinations will there be if the couple chooses to have four boys and two girls?
(1 pt)

4. The ability to tongue-roll is controlled by a dominant allele N. In an Institute consisting of 8000

students, it was found that 3500 were tongue-rollers. Assuming that the population is in Hardy-Weinberg
equilibrium,
a. Compute for the frequency of the recessive allele (2 pts)
b. Compute for the frequency of the heterozygous individuals in the population (2 pts)

5. Determine the genotypes of the pea plants involved in the following crosses. Round (R) is dominant to
wrinkled (r) and Yellow (Y) is dominant to green (y). (4 pts)
Round-Yellow Seeds

Round-Green Seeds

Wrinkled-Yellow
Seeds

Wrinkled-Green
Seeds

a.

31

29

28

32

b.

34

31

6. Determine whether your answer in #5a is correct given the Chi-square table below. Write only the
following:
a. Computed Chi (3 pts)
b. Tabulated Chi (1 pt)
df

(0.01)

6.635

9.210

11.345

13.277

15.09

7. In a survey of 1000 people, 100 are blood type N and 300 are blood type M.
a. Compute for the frequency of allele M. (2 pts)
b. Compute for the frequency of allele N. (2 pts)
c. After 3 generations of random mating, what would be the expected genotypic frequencies for
blood types M and MN individuals? (4 pts)

8. White-eye color in Drosophila is an X-linked recessive trait. Professor Ken mated a heterozygous redeyed female Drosophila with a white-eyed male. They bore 120 maggots. Assuming a 60% survival rate,
a. How many of the offspring will be white-eyed females? (2 pts)
b. What is the probability that a male will be white-eyed? (2 pts)