Small intestine cancer - Wikipedia, the free encyclopedia

7/9/15, 23:21

Small intestine cancer

From Wikipedia, the free encyclopedia

In oncology, small intestine cancer, also

small bowel cancer and cancer of the
small bowel, is a cancer of the small
intestine. It is relatively rare compared to
other gastrointestinal malignancies such as
gastric cancer (stomach cancer) and
colorectal cancer.
Small intestine cancer can be subdivided
into duodenal cancer (the first part of the
small intestine) and cancer of the jejunum
and ileum (the later two parts of the small
intestine). Duodenal cancer has more in
common with stomach cancer, while cancer
of the jejunum and ileum have more in
common with colorectal cancer. Five year

Small intestine cancer

Picture of a carcinoid tumour that encroaches into lumen of the small

bowel. Pathology specimen. The prominent folds are plicae circulares, a
characteristic of small bowel.
Classification and external resources

survival rates are 65%.[1]

ICD-10 C17
(http://apps.who.int/classifications/icd10/browse/2015/en#/C17)

Several different subtypes of small intestine

cancer exist. These include:

ICD-9- 152 (http://www.icd9data.com/getICD9Code.ashx?icd9=152)

CM

adenocarcinoma
gastrointestinal stromal tumor
lymphoma
ileal carcinoid tumor

MeSH D007414 (https://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?

field=uid&term=D007414)

Contents
1 Risk factors
2 Research
3 Additional images
4 References

Risk factors
Risk factors for small intestine cancer include:[2][3]
Crohn's disease
Celiac disease
Radiation exposure
https://en.wikipedia.org/wiki/Small_intestine_cancer

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Small intestine cancer - Wikipedia, the free encyclopedia

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Hereditary gastrointestinal cancer syndromes: familial adenomatous polyposis, hereditary nonpolyposis

colorectal cancer, Peutz-Jeghers syndrome
Males are 25% more likely to develop the disease
Benign tumours and conditions that may be mistaken for cancer of the small bowel:
Hamartoma
Tuberculosis

Research
Little research is conducted on these cancers due to their relative rarity
when compared to the more common colorectal cancers. APC-min mice
which carry a gene deficiency corresponding to that of humans with FAP
also go on to develop small intestinal tumors, though humans do not.

Additional images

Endoscopic image of adenocarcinoma

of duodenum seen in the post-bulbar
duodenum.

Micrograph of a small
intestine
neuroendocrine tumour.
H&E stain.

References
1. "SEER Stat Fact Sheets: Small Intestine Cancer" (http://seer.cancer.gov/statfacts/html/smint.html). NCI. Retrieved
18 June 2014.
2. Delaunoit T, Neczyporenko F, Limburg PJ, Erlichman C (March 2005). "Pathogenesis and risk factors of small bowel
adenocarcinoma: a colorectal cancer sibling?". Am. J. Gastroenterol. 100 (3): 70310. doi:10.1111/j.15720241.2005.40605.x (https://dx.doi.org/10.1111%2Fj.1572-0241.2005.40605.x). PMID 15743371
(https://www.ncbi.nlm.nih.gov/pubmed/15743371).
3. Chen AC, Neugut AI. Malignant Neoplasms of the Small Intestine. eMedicine.com. URL:
http://www.emedicine.com/MED/topic2651.htm. Accessed on: June 2, 2006.

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Small intestine cancer - Wikipedia, the free encyclopedia

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Categories: Gastrointestinal cancer

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