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Page 1 of 2
Editorials
EDITORIALS
Comparing risk prediction models
Should be routine when deriving a new model for the same purpose
1
Gary S Collins senior medical statistician , Karel G M Moons professor of clinical epidemiology
Centre for Statistics in Medicine, Wolfson College Annexe, University of Oxford, Oxford OX2 6UD, UK ; 2Julius Centre for Health Sciences and
Primary Care, UMC Utrecht, 3508 GA Utrecht, Netherlands
1
gary.collins@csm.ox.ac.uk
For personal use only: See rights and reprints http://www.bmj.com/permissions
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Page 2 of 2
EDITORIALS
National Institute for Health and Clinical Excellence. Lipid modification: cardiovascular
risk assessment and the modification of blood lipids for the primary and secondary
prevention of cardiovascular disease. 2008. CG67. http://guidance.nice.org.uk/CG67.
Altman DG, Vergouwe Y, Royston P, Moons KGM. Prognosis and prognostic research:
validating a prognostic model. BMJ 2009;338:b605.
Siontis GCM, Tzoulaki I, Siontis KC, Ioannidis JPA. Comparisons of established risk
prediction models for cardiovascular disease: systematic review. BMJ 2012;344:3318.
Toll DB, Janssen KJ, Vergouwe Y, Moons KG. Validation, updating and impact of clinical
prediction rules: a review. J Clin Epidemiol 2008;61:1085-94.
Steyerberg EW, Borsboom GJ, van Houwelingen HC, Eijkemans MJ, Habbema JD.
Validation and updating of predictive logistic regression models: a study on sample size
and shrinkage. Stat Med 2004;23:2567-86.
Rifai N, Altman DG, Bossuyt PM. Reporting bias in diagnostic and prognostic studies:
time for action. Clin Chem 2008;54:1101-3.
Moons KGM, Altman DG, Vergouwe Y, Royston P. Prognosis and prognostic research:
application and impact of prognostic models in clinical practice. BMJ 2009;338:b606.
Brindle P, Beswick A, Fahey T, Ebrahim S. Accuracy and impact of risk assessment in
the primary prevention of cardiovascular disease: a systematic review. Heart
2006;92:1752-59.
Collins GS, Mallett S, Omar O, Yu LM. Developing risk prediction models for type 2
diabetes: a systematic review of methodology and reporting. BMC Med 2011;9:103.
Collins GS. Opening up multivariable prediction models: consensus-based guidelines for
transparent reporting. BMJ Blogs 2011; http://blogs.bmj.com/bmj/2011/08/03/gary-collinsopening-up-multivariable-prediction-models/.
Vickers AJ, Elkin EB. Decision curve analysis: a novel method for evaluating prediction
models. Med Decis Making 2006;26:565-74.
Moons KG, Kengne AP, Grobbee DE, Royston P, Vergouwe Y, Altman DG, et al. Risk
prediction models: II. External validation, model updating, and impact assessment. Heart
2012;98:691-8.
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