Escolar Documentos
Profissional Documentos
Cultura Documentos
windpipe to contract, which accounts for their role in allergyinduced asthma. Asthma patients suffer from shortness of
breath and wheezing caused by constriction of the airways.
Drugs that modify the production or activity of leukotriene are
known as leukotriene inhibitors (they are also called leukotriene
receptor antagonists or leukotriene modifiers). Some of these
drugs work by limiting the production of leukotrienes by cells
such as leukocytes (a type of white blood cell), while others
block leukotrienes from binding with their receptors on smooth
muscle cells. If the fatty signaling molecules cannot bind with
their cellular targets, they cannot trigger muscle contraction.
MONTELUKAST (SINGULAIR)
REFERENCES
http://www.webmd.com/
http://www.healthline.com/health/allergies/leukotriene
http://www.sciencemag.org/
http://www.atsjournals.org/