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Total number of hours (per semester) from

curriculum (84)


Name of discipline

Type of final evaluation (E / V /
Year of study
Numbers of
Discipline regime (Co compulsory, Op optional F - facultative)
Total number of
Total number of hours from
Total number of individual
50 hours per
study hours

Head of the discipline


Prof. Dr. Simona Mihaela Slatineanu

* If the discipline has more semester of study, fill one syllabus for each semester




Morpho-functional Sciences

Morphofunctional Sciences








** C course, L labs activities, P project or

practical lessons

Minimum knowledge needed by students to understand the course concepts / internships / practical
basic knowledge (high school) about anatomy and physiology of the body;
knowledge about cellular physiology (1st year)
knowledge about biochemistry, biophysics, cell biology (1st year)

Objectives of the discipline

General objective:
The students will gain knowledge about the normal functions of the body and will be able to understand
into an integrative manner physiological processes, from cell to organism, thus gaining a solid foundation
for clinical medical sciences.
Educational offer of the discipline:
- theoretical training of the students in order to assimilate knowledge through systematic information on
functional integration phenomena from cell to organism
- presentation of some theoretical concepts during the practical classes by classic experiments (video) and
various computer simulations (mostly interactive);
- acquiring the practical skills by the students on proper execution of some manoeuvres, based on accurate
procedures and understanding the issues explored;

- education of medical students in the spirit of the accurateness of the medical act, and the understanding
of the basic science crucial role for its level and for their professional training.
Lecture syllabus
Hours No.
LECTURE 1. Digestion physiology. Morphological and functional characteristics of
the digestive system. Mechanical and physical phenomena along digestion and their


LECTURE 2. Digestion physiology. Chemical transformation of food along

digestion. Digestive secretions and their regulation.

LECTURE 3. Digestion physiology. Absorption of the nutrients. Regulation of food

intake: hunger, satiety, energy metabolism and weight status.

LECTURE 4. Liver physiology. Roles of the liver: digestive, metabolic, excretory.

PBL: jaundice types.

LECTURE 5. Physiology of the endocrine glands: morpho-functional characteristics

of the endocrine glands. The concept of hormone, synthesis, transport, action
mechanisms of hormones.

LECTURE 6. Mechanisms of the hormone secretion regulation. Morphological and

functional characteristics of the neuro-endocrine transducers

LECTURE 7. Physiology of adenohypophysis. Physiology of neurohypophysis

LECTURE 8. Physiology of thyroid gland. Physiology of the parathyroid glands.

Phospho-calcic metabolism.

LECTURE 9. Physiology of the adrenal glands. Physiology of endocrine pancreas.

Physiology of the epiphysis. Physiology of endocrine thymus

LECTURE 10. Physiology of the gonads

LECTURE 11. Physiology of the central nervous system: morpho-functional

organization of CNS. Reflex center function of the spinal cord, medulla oblongata,
ponce, mesencephalon, reticular formation.

LECTURE 12. Physiology of the afferent systems. Physiology of mechanoreceptors.

Physiology of the visual receptor. Physiology of the auditory receptor. Physiology of
the vestibular receptor.

LECTURE 13. Physiology of the olfactory receptor. Physiology of the taste receptor.
Physiology of the conduction pathways. Physiology of somatosensory cortical areas.

LECTURE 14. Phsyiology of the efferent systems. Physiology of the pyramidal

system. Physiology of the extrapyramidal system

Practical lessons syllabus - 42 ORE

PL 1: Oral digestion: sampling of saliva; secretory mechanisms; chemical examination
of saliva; digestive role and thermolability of the salivary amylase
PL 2: Gastric digestion: gastric juice sampling; secretory mechanisms; HCl and
lactic acid determination, measurement of the gastric juice acidity; action of


PL 3: Intestinal digestion: bile, pancreatic and intestinal juice sampling; secretory

mechanisms; determination of the pancreatic amylase.

PL 4: Differentiation of gastric and intestinal proteolysis products; in vitro intestinal


PL 5: Intestinal digestion. Chemical examination of bile. Emulsifying properties of

PL 6: Physiology of the endocrine glands. Methods for the study of the function of
endocrine glands; Physiology of the pituitary gland: radioimmunoassay of pituitary
hormones; role of the pituitary in melanogenesis, action of oxytocin upon the uterine
smooth muscle.

PL 7: Physiology of the endocrine glands. Physiology of the thyroid and parathyroid

glands: determination of basal metabolism, reflexography.

PL 8: Physiology of the endocrine glands. Physiology of gonads and adrenocortical

glands: early pregnancy diagnosis: Galli- Mainini test and immunological methods;
Thorn test,.

PL 9: Physiology of the somatic effector system Dinamometry. Chronaxy. Global

and motor unit electromyography.
PL 10: Physiology of the peripheral nervous system. Relative infatigability of nerve.
Motor conduction speed, electronervogram, sensitive conduction speed. H reflex.
PL 11: Reflex function of the spinal cord and medulla oblongata. Laws of spinal cord
reflexes. Somatic and vegetative reflexes of clinical relevance.


PL 12: Physiology of the central nervous system. Electroencephalography; evoked

cortical potentials.

PL 13: Sensorial physiology; Determination of taste threshold. Determination of

visual acuity. Determination of tactile discrimination threshold; Audiometry.

PL 14: Practical exam

Practical skills achieved by the end of the year/semester

1. Measurement of the gastric juice acidity and secretor debits
2. Bile pigment detection
3. Pancreatic amylase determination
4. Early pregnancy test (Galli-Mainini test)
5. Dinamometry. Chronaxy
6. Somatic reflexes of clinical relevance (biceps, triceps, stylo-radial, ulnar, patellar, achillean)
7. Pupillary reflexes examination (pupillary light reflex, accommodation reflex)
8. Determination of taste threshold
9. Determination of visual acuity
10. Determination of tactile discrimination threshold.

Percentage of final grade

(Total = 100%)

The final grade results from

exam / colloquium answers (final evaluation):
MCQ test
Oral and practical exam


- final answers at the practical lessons


- revisions tests during the semester


- activities like subjects / papers / essays / translations /

projects etc.
- other activities (SPECIFY): colloquium


Describe the practical final evaluation E / V (eg written paper (descriptive and / or multiple
choice test and / or problems, etc.), oral examination, individual or group colloquium, project,
- Oral practical exam followed by unique MCQ test

Estimate the total time (hours per semester) of the individual study activities required
(fill with 0 activities not required)
1. Reading and study of the lecture notes
8. Preparing oral presentations
2. Study after book, lecture handouts
3. Study of the minimal references
4. Suplimentary documentation at the
5. Specific activity training
Seminars and / or LABORATORY
6. Making of themes, essays, translations,
7. Preparing control papers

9. Preparing final examination


10. Consultations

11. Practical documentation

12. Internet documentation

13. Other activities ....

14. Other activities....


TOTAL number of hours of individual

study (per semester) =50

Compulsory references:
1. Berne RM, Levy MN, Koeppen BM, et al: Berne & Levy: Principles of
Physiology, 5th ed. St. Louis, Elsevier Mosby, 2004

2. Guyton AC, Hall JE: Textbook of Medical Physiology, 11th Ed. Philadelphia,
Saunders, 2006.
3. Slatineanu SM, Dumitriu IL, Vata LG, Cojocaru E, Gurzu B: Principles and
methods for practical lessons of physiology, 1st ed. Iasi, Gr T Popa, 2012
4. Slatineanu SM, Dumitriu IL, Vata LG, Cojocaru E, Gurzu B: Handbook of
practical physiology and functional explorations, 1st ed. Iasi, Gr T Popa, 2012
Supplementary references for Physiology lectures and practical lessons
1. Despopoulos A, Silbernagl S: Color Atlas of Physiology, 5th ed. Thieme, 2003
2. Ganong WF: Review of Medical Physiology, 22nd ed. New York, McGraw-Hill,
3. Sherwood L: Fundamentals of physiology: a human perspective, 3rd ed. Belmont,
Calif., Brooks/Cole, 2006.


Signature of Didactic activity coordinator