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International Journal of Medicine and

Pharmaceutical Science (IJMPS)


ISSN(P): 2250-0049; ISSN(E): 2321-0095
Vol. 6, Issue 1, Feb 2016, 119-124
TJPRC Pvt. Ltd.

A STUDY ON THE PREVALENCE OF BREAST CANCER


IN WOMEN AT THI-QAR PROVINCE
LAMYAA KADHIM OUDAH
Department of Pathological Analyzes, College of Science, University of Thi-Qar, Iraq
ABSTRACT
The research conducted on the statistical hundred women with breast cancer from Hussein Teaching Hospital
throughout the saved data in the records for the time period from March 2014 to March 2015, the data classified
according to age group, residential areas and marital status, the results showed that more breast cancer was for the class
age (41-50) and the lowest for the age group (21-30).The researches showed that the results of the province of Nasiriya,
Shatra and Suq-Alshyoohk are the highest breast cancer while it was less infected in (Rifai), and for the social situation,
the married women were the most vulnerable to the breast cancer, and to a lesser extent in unmarried.
KEYWORDS: Breast Cancer, Thi-Qar

INTRODUCTION
The cancer is type of the kinds of diseases make infected cells grow and change and multiply are out of
control and is characterized by cells Aggressive and the ability of these dividing cells to Invasion neighboring
tissue and destroy it, or move to tissues far in the process we call metastasis (Anna, 2003). These capabilities are

Original Article

Received: Nov 27, 2015; Accepted: Feb 05, 2016; Published: Feb 09, 2016; Paper Id.: IJMPSFEB201614

the characteristics of a malignant tumor on the opposite benign tumor, which is characterized by a specific growth
and the inability to invasion and has no ability to move or metastasis. It can also be benign tumor development to
malignant cancer at some cases (Waters, 2007).
Cancer can affect all age groups even when human embryos, but the risk of infection increases as people
age. The cancer cause of death by 13% of all deaths. The American Cancer Society refers to the death of 7.6
million people a cancer patient in the world in 2007. The cancer affects the human forms of it infecting animals and
plants alike (ACS, 2014).
Often, due to healthy cells turning cancerous cells to changes in the genetic material. These changes may
cause carcinogenic factors such as smoking, or radiation or chemicals or infectious diseases (such as virus
infection). There are also encouraging factors for the incidence cancer such as a random error or mutation in DNA
copy of DNA in cell division, or because of inherited this error or mutation from the mother cell. (Runnak etal,
2009).

Cancer is classified as a type of originating from tissue cancer (cancer Location) and the nearest intact

cells similar to cell - cancer (cancer Histology). (Rrise et al; 2003). And breast cancer is a form of cancer diseases
that affect the breast tissue and is more common in women of the tumor and its causes are not known accurately,
but there are factors that help to breast cancer, including genetic factors, or the start of menstrual cycles early, or
use the hormone estrogen therapy for a long period (Adami etal., 1990).

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120

Lamyaa Kadhim Oudah

Symptoms begin by mass appearance in the breast discovered by women themselves, bleeding from the nipples,
the contraction of the skin becomes above the tumor-like orange peel, swell glands and especially the lymph underarm, and
the treatment is through surgery, or radiation therapy, or chemotherapy, or hormone therapy (Weinbrg, 2006).
At present most of the treatment of cancers may be cured, and this depends on the type of cancer, location, and
stage. When cancer is detected, begins treated with surgery or chemotherapy and Radiotherapy (Devita etal 2008). Through
research developments, the production of drugs could be able to target cancer cells by discriminating on the molecular
level, which reduces the possibility of targeting healthy cells.

MATERIALS AND METHODS

The data are collected from the records of 100 women patients with breast cancer from Al-Hussein Teaching
Hospital in Thi-Qar of the time period from March 2014 until the March 2015. The information's were classified
that has been counted according to age, residency and social situation.

Statistical Analysis
Conducted statistical analysis of the data studied for the purpose of research using SPSS using Chi-square test x2

to compare the results of the comparison between the results studied. AL-Baladawey. (2009).

RESULTS
Table 1 shows the number of patients of women by age group. The results showed that the higher percentage of
the disease in the age group (50-41) and by (34%), followed by group (40-31) and by (28)%, (60. 51) by (18%) and (7061) and by (12%) and then (30-21) by (% 8). And there are significant differences under the level of the probability P =
0.01.
Table 1: the Percentage of the Proliferation of Breast Cancer by Age Group
Age Group
21-30
Patients N=100
8
Percentage
8%
2
X=23,600, df=5 p0.05

31-40
28
28%

41-50
34
34%

51-60
18
18%

61-70
12
12%

Figure 1: The Distribution of Patients by Age Group

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A Study on the Prevalence of Breast Cancer in Women at Thi-Qar Province

121

Table 2 showed the current search results variation the percentage of cases of breast cancer depending on the
residential areas for patients where the highest percentage was Nasiriya, (30%), followed by Shatra (25%), Suq by (18%)
Gharraf (15%) and then Rifaee, (12%).
Table 2
Sample
Patients
Nasiriya
N=100
30
Percentage
30%
2X= 10.900, p0.05

Shatra
25
25%

Areas
Suq Gharraf
18
15
18%
15%

Rifaee
12
12%

Figure 2: Patients Distribution by Residential Areas


Table 3 shows that 80% of patients with breast cancer are married, and 20%
Unmarried according to the social status.
Table 3: Percentage Distribution of Patients by Social Status
Social Status Patients N=100
Married
80
Unmarried
20
X= 36.000 p0.01

Percentage
80%
20%

DISCUSSIONS
Breast cancer is one of the most common cancer among women and is one of the important reasons leading to
death among women (hellekson, 2002) therefore constitutes an important health problem in all countries of the world of
breast cancer rates have increased across the world's population has increased in the countries which had rates of a few
injury (Ahmed, 2003). Breast cancer is in Iraq of the most common cancer among women has included 19.8% of other
types of cancers affecting women during the years 1976-1985 and reached 24% during the years 1989 to 1995, while
reached 30% during the years 1995 to 1997 and in 2000 reached 31% (Iraq National cancer Registration). Scored in 2434
with breast cancer in all over the Iraq in 2005, which accounts for about 31.57% of the total cases of cancer that affects
women in Iraq (Iraq Cancer Registry 2008).
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Lamyaa Kadhim Oudah

The results of the current study showed that the average age of infection with breast cancer between age groups
(50-41) was (34%) as study (Runnak et al., 2009) In the north of Iraq, said the average age of infection 47.4 years, but the
greatest frequency of the injury was from age group (45-36) years, and Malaysian study conducted in Norsaadah, et al
(2005) that the average age of injury 46.3 years and the age group (55-41 years) the largest frequency of infection because
most cancers develop slowly over time, and that the increase in mass weight breast tissue as a result of old age is a risk
factor for breast cancer (Ross et al., 2008).
The old and one of the most important risk for breast cancer factors after sex with adult women in old age has a
higher risk for breast cancer has been found that this risk increases by four times after the age of 50 years (2001,. Christine
et al). Because of the lack of ovulation and the high level of female sex hormones estrogen and progesterone (Kaaks et al.,
2005), is working to increase division of breast tissue and shows the effect of these hormones in increased risk in women
who have to have menstrual early and menopause in older people for exposure to high levels of hormones during period of
life produced by the adrenal gland and adipose tissue that (Lester, 2008). Also, lack of physical activity and the lack of a
healthy diet contributes to a significant role for the occurrence of breast cancer, especially in women who have reached the
Post- Menopausal because of its effect on increasing the level of the hormone estrogen in abundance within the
tissue(Travis et al; 2003), in the table 2 that the percentage of infection among women in Nasiriya was 30% and this is
what he found (Darweesh., 2009). Where the injury was 53.1% in urban areas and 47.9% in rural areas. And explained
(Kumar et al., 2005) The rate of breast cancer is higher in rural more than urban areas. And explain the the results as a
result of differences in environmental factors between rural and the city in addition to the difference in the economic level
(Gunter, 2009).
CONCLUSIONS
The results also showed in the table 3 The married women more susceptible to breast cancer, where percentage
was 80% in married women while it was (20%) in non-married may due to pregnancy if terms of increased estrogen levels
in the body, leads to increased risk of injury breast cancer (Dimitrakakis et al; 2010), Because of its effect on sensitive
tissues of estrogen that leads to the formation of the tumor (Newcomb, 2001) as the estrogen basic role in the development
of breast tissue and the development of channels stimulating cells to proliferate through the occurrence of genetic
mutations work on the growth and differentiation of breast cells abnormally (Hankinoson, 2005 ). The study, conducted by
the Norsaadah et al; (2005) The married women Older than unmarried added the output to the age of the child's birth,
number of children and hormonal factors influence. Also, areas where factories abound, especially in the present time
abounded means of environmental pollution such as electric generators and radiation resulting from chemical weapons
used in the US-Iraq war was considered a major factor cause of the occurrence of cancer diseases of various kinds.
REFERENCES
1.

Ahmad, M.(2003).Risk Factors for breast cancer among woman attending breast clinic in university Malaya, Medical center,
kuala Lumpur NCD Malaysia.,2(4):23-31.

2.

Akram, W.(2009).Sreening of Breast mass in Iraqi Females :Al-kindy Hospital Breast clinic. Al-kimdy college of medicine,
unversity of Bagdad, Bagdad, iraq, American Journal of Infections Diseases 5(4):320-323.

3.

Christine, K.J; Aronson, K.D.and Mark, G. (2001) Review of life style and Environmental Risk Factors for Breast cancer,
Minister of public works and Government services canada, cat. NO. H3a-586.

Impact Factor (JCC): 5.4638

NAAS Rating: 3.54

A Study on the Prevalence of Breast Cancer in Women at Thi-Qar Province

4.

123

Darweesh,A. (2009). Risk Factors of Breast cancer among palestinian women in North Weast Bank. M. sc - thesis, Al-Najah
National university, Nablus, palestine.

5.

Hellekson, K.L.(2002). American cancer society issues guidelines for the early dedectio of ancer. Am Fam physician; 66:682684

6.

Nors aadah, B.N; Rusli, A.K; Imran and Nairg, T,w.(2005).Risk factors of breast cancer in woman in kelantan, Malaysia.
Singopore Med J54642):698-705

7.

Waters, J. M. and Barclary, L.J. (2007). Dose growth hormone drive breast and other cancers ? J. Endocrinology vol. 148 (10)
: 45 33-4535.

8.

Newcomb,P.A.(2001).Endocrin gland.histonots,awgustfason;9(6)pp:163-173.

9.

Kumar, V.;Abbas, A.K. and Fausto, N.(2005). Robbins and cotran pathologic basis of Oisease. Elseviersaanders. 1138-1146.

10. Dimitrakakis,C.;Zava,D;Marinopoulos,P;T sgginou,A.; Antsaklis,and Glaser,R.(2010). Low salivary testosterone leves in


patients with brest cancer.BMC Cancer,Bio.med.central;10(547) pp:1471-2407.
11. Gunter,M.J.;

Hoover,

A.

H(.2009),insulin-like

growth

facter-1,andrisk

of

brest

cancer

in

postmenopausal

women.j.Natl.cancer.inst;101(14);pp:1030-1031.
12. Weinberg, R.A.(2006).the Biblogy of cancer. Farland science. 410-440.
13. AL- Baladawey,.2009,A.A.(2009). Statical packages for social sciences foruse SPSS program Chi-squire pp: 442.
14. Devita,V.T.; Lawrence,T.S and Rosenberg,S.A.(2008). Cancer:Principles & Practice of Oncology.cancer of the brest,malignant
tumors of the brest;pp1606-1650.
15. Anna, H.I.C.M.D. (2003),the Development of Diagnostics for Breast cancer, Yerevan state midical University.
16. Iraq Cancer Registry.(2008). Iraq cancer board,ministry of the health.Bagdad, Irap.

17. Ross,J and Hatzis,C.symmans( 2008). Commercialized multigene predictors of clinical oucome for breast
cancer.oncologist;(13) pp:477-493.

18. Laster, S.C.2008.The breast.In Kumar V, Abbas, Fusto,N, and Aster,JC.(eds) Robins and Cotran pathologic basis of disease,
8thend.sunders,philadephia ; pp:1065-1071.

19. Kaaks,R; Berrino,F and Key,T.2005.Serum sex steroids In premenopausal women and breast cancer risk Within the European
prospective Investigation in to Cancer and Nutrition(EPIC).J.Natl.Cancer.Inst; (97)pp:755-765.

20. Rise, L.A.G.; Eiser, M.p.; kosary, C.L.; Hankey, R.F.; Miller, B.A.; Clegg, L.and Edwards, B-K (2003) SEER cancer stastics
Review, 1973-1999, National cancer institute. Bethsda, MD.
21. Travis,R.C and Key,T.J.(2003).Oestrogen expousure and breast cancer : An7.risk. Breas.Cancer.Res; 5(5)pp:239-240.

22. Ademi,H.O.; Adam,G.;Boyle,R.;Ewentz,M and Lee, N.C.(1990). Brestcancer etiology Int.J.Cancer; (5)pp:22-39.
23. Runnak, A.;Majid. H.A.;Mohmmed, H.M;Saeed, B.M; safar, R.MR. and Michael, D.H.(2009) Breast cancer in kurdish
womanof nothern Iraq: incidence, clinical stage, and case control analysis of parity and family risk. Divion of onology,Hewa
Hematology and onology.

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