1.

Reserpine on hydrolysis gives:

(a) Reserpicacid + Methylalcohol +Trimethoxy cinnamic acid
(b)Reserpic acid + Acetic acid + Trimethoxy benzaldehyde
(c) Reserpicacid + Methylalcohol +Trimethoxy benzoic acid
(d)Reserpic acid + Methylalcohol +Trimethoxy Cinnamaldehyde
2. Salbutamol sulphate IP is assayed by
(a) Direct titration with standard sodium hydroxide solution
(b) Direct titration with standard sodium hydrochloric acid
(c) A known amount of standard acid is added and excess is titrated with standard alkali
(d) Dissolve in glacial acetic acid and titrated with standard perchloric acid using oracet
blue.
3. Powder ergot when treated with sodium hydroxide solution develops?
(a) A strong odour of ammonia
(b)A strong odour of trimethyl
(c) A strong odour of indole
(d)A strong odour of urea
4. For the registration of pharmacist in the various states, the Pharmacy Act
provide for
the constitution of:
(a) Registration of tribunals
(b) Registrar of Co-operative societies
(c) Registrar of state pharmacy council
(d)Registrar of central pharmacy council
5. Powder digitalis is dried at temperature
(a) Not exceeded 60 C
(b) 65 C
(c) 75 C
(d) 100 C
6. Prazepam differ in structure from diazepam by
(a) N- methyl group
(b) N cyclopropyl group
(c) N-cyclopropyl methyl group
(d) N-propyl group
7. The mechanism of action of rifampicin involve
(a) Inhibition of bacterial DNA directed RNA polymerase
(b) Inhibition of mycolicacid synthesis
(c) Inhibition of protein synthesis
(d) Inhibition of transpeptidase
8. The volume of did tribution of drugs is
(a) An expression of total body volume
(b)A measure of total fluid volume
(c) A relationship between the total amount of drug in the body and the concentration of
the
drug in the blood
(d)Proportional to bioavailability of the drug
9. Resolution of a spectrophotometer is
(A) Its a wavelength range
(B) Its ability to distinguish adjacent absorption bands
(C) its a capacity for its continuous use
(D) Its power to gather light according to source
10. Glandular hair growing having a unicellular or occasionally a short uniserate
pedicel with a unicellular orbicellular terminal glandis characteristics of

(a) Senna leaves

(b) Belladonna leaves
(c) Datura stramonium leaves
(d)Digitalis Purpurea leaves
11. Skeletal muscle relaxant produced by the drug ______is effectively
antagonized by
neostigmine
(a) Diazepam
(b)Succinylcholine
(c) Tubocurarine
(d)Aminophylline
12. Vitamin D2
(a) 22, 23-Dihydro -5,6cis Ergocalciferol
(b) 5, 6 cis- chlorcalciferol
(c) 7- Dehydrocholesterol
(d) 21,24 dihydro 5,6 cis Ergocalciferol
13. R.W. C. is used to identify the strength of?
(a) Antibiotics
(b)Antipyretics
(c) Antiseptic
(d)Antiinflammatory
14. The essential structural unit for the anthelmentics activity of mebendazole is
(a) Benzoyl group
(b)Benzimidazole
(c) Methyl carbamates
(d) Imidazole
15. The anticoagulant activity of heparin sodium injection IP is estimated using:
(a) Female rats
(b) Male rats
(c) Rabbits
(d) Sheep
16. Infrared spectroscopy is a convenient method for understanding of
(a) Drug receptor interaction
(b) Functional group identification
(c) Physiochemical properties
(d) Conformational properties
17. Most commonly used amtimicrobial agent for intraperitoneal dialysisis
(a) Chlorocresol
(b) Benzalkonium chloride
(c) Isopropyl alcohol
(d) None of the above
18. In the steroid nucleus, they are
(a) Six chiral center with nucleus i.e. 5,8,9,10,13, and 14
(b) Seven chiral center with nucleus i.e. 3,8,9,10,11, 12 and 14
(c) Six chiral center with nucleus i.e. 3,8,9,10,11, and 12
(d) Six chiral center with nucleus i.e. 5,7,9,10,13, and 16
19. Sulphomethoxazoleis an antibacterial drug. It is a
(a) Short acting drug
(b) Short and intermediate acting drugs
(c) Long acting drugs
(d)Mixed acting drugs
20. Wavenumber is the number of waves

(a) Per second

(b) Per centimeter
(c) Per inch
(d) Per cm3
21. The raw material for synthesis of propranolol is
(a) Naphthylamine
(b) napthol
(c) -naphthol
(d) 1- nepthaldehyde
22. All the statement mentioned below about choral hydrate is true EXCEPT that it
(a) Produces hypnosis
(b) Produces analgesia
(c) Produce dependence
(d) Irritate gastric mucosa
23. Which is ideal combination for testing the solubility of an enteric coated
capsule in
alkaline medium?
(a) Sodium bicarbobnate + Potassium hydroxide + Pepsin
(b) Sodiumbicarbobnate + Sodiumtauroglycocholate+Papain
(c) Sodium bicarbobnate +Pancreatin +Sodium tauroglycocholate
(d)Sodiumbicarbobnate + Billirubin
24. Oxazepam is used in relief of psychoneurosis. It has lower incidents of side
Effects and reduced toxicity due to
(a) N-demethylation
(b) Ring oxidation
(c) Aromatic hydroxylation
(d) Conjugation of 3- hydroxyl group
25. One of the detectors used in gas chromatography
(a) Bolometer
(b) Thermal conductivity detector
(c) Golay detectors
(d) Geiger Counter
26. Alkloids in cinchona bark are detected by
(a) Iodine test
(b) Thalleioquin test
(c) Liebermann burchard test
(d) Nesslers test
27. 2- amino -5-chorbenzophenone is the convenient starting material for the
synthesis of
(a) Nitrazepam
(b) Diazepam
(c) Chloramphenicol
(d)Trimethoprim
28. Side effect of Chloramphenicol is?
(a) Gray-baby syndrome
(b) Jaundice
(c) Discolouration of teeth
(d) Obesity
29. Papaverine is
(a) 6, 7 - dimethoxy -1- (3, 4 dimethoxybenzyl) isoquinoline
(b) 6, 7 - dimethoxy -1- (3, 4 dimethyl benzyl) isoquinoline
(c) 6, 7 - dimethoxy -1- (3, 4 dimethoxybenzyl) quinoline

(d) 6, 7 - dimethoxy -1- (3, 4 dimethyl benzyl) quinoline

30. Cortisone is
(a) 4 Pregnane-12 , 21 diol- 3, 20- Dione
(b) 4 Pregnane-17 , 21 diol- 3, 11, 20- trione
(c) 4 Pregnane-16 , 21 diol- 3, 11, 20- trione
(d) 4 Pregnane-17 , 21 diol- 3, 11, - Dione
31. Pregnenolone, an intermediate in synthesis of steroids, on oppeneur
oxidation gives
(a) Progesterone
(b) 9 - flurocortisone
(c) Triamcinolone
(d) methyl Prednisolone
32. Carbamazepine is tricyclic antidepressant, it is classified as
(a) Benzodiazepine
(b) Arylalkonolamine
(c) Iminostilbene
(d) Benzimidazole
33. Sulfa drugs can be conveniently estimated using the reagent
(a) 4, 4 Dithiobis (2-nitrobenzoic acid)
(b) Tris-(hydroxyl methyl) amino methane sodium nitrate
(c) N-(1-nepthyl) ethylenediamine
(d) N-ethylmalcimide
34. Testosterone can be commercially synthesis from
(a) Sarsapogenin
(b) Mexogenin
(c) Oubagenin
(d) Halotensin
35. Ehlrichs reagent is
(a) Bismuth iodide solution
(b) p-dimethyl aniline solution in alcohol
(c) p-dimethyl amino benzaldehyde solution
(d) p-dimethyl aniline solution in alcohol
36. The neurotransmitter is release the sympathetic nerve fiber is
(a) Epinephrine
(b) Norepinephrine
(c) Acetylcholine
(d) Physostigmine
37. Resolution of monochromator is the ability to distinguish
(a) As aseparate entities adjacent spectral features
(b) Separation of different colours
(c) Separation of UV light and Visible light
(d) Dispersing Characteristics
38. Important activity noticed in testosterone
(a) Androgenic, Myotropic and Anabolic
(b) Progestinal, Myotropic and Anabolic
(c) Estrogenic, Myotropic and Anabolic
(d) Androgenic, Optometric and Catabolic
39. Amygdalin on hydrolysis gives
(a) Mendelonitrile +Benzaldehyde
(b) Mendelonitrile + Benzaldehyde +Glucose
(c) Mendelonitrile +Glucose
(d)Mendelonitrile + Benzaldehyde +Rhamanose

40. The presence of unpaired electron in metalion complex meant for special
analysis is called
(a) Paramagnetic (b) Dimagnetic (c) Bimagnetic (d) Unimagnetic
41. The ilkovic equation in the polarographic measurements is given by

42. The stationary phase in TLC is

(a) Adsorbent
(b) Liquid held between glass plate and adsorbent
(c) Glass plates
(d) None of the above
43. Digoxin
(a) Has its action terminated by metabolism in the liver
(b) Has a plasma t1/2 of 6 hours
(c) Should be given half of its normal dose to hypothyroid patients
(d) Provide benefit in atrial fibrillation by increasing the force of contraction
44. Drug used in treatment of bronchial asthma usually
(a) Block both and adrenergic receptors
(b) Stimulate receptors but block receptor.
(c) Stimulate receptors but block receptor.
(d) Stimulate and / or receptors
45. Vinca alkaloids are isolated from
(a) Catharanthus roseus and contain indole and indolinemoieties
(b) Rosco chromogens and contain indole and indolinemoieties
(c) Catharanthus roseus and contain quinoline and quinaldine moieties
(d) Catharanthus indicus and contain indole and quinoline moieties
46. All of the following physicochemical constants are useful in predicting the
solubility
of a Drug except?
(a) Dielectric constants
(b) pH of a solution
(c) pKa of the drug
(d) Valency
47. The 5 pregnane is said to have a
(a) trans-anti-trans-anti-trans back bone
(b) cis-anti-trans-anti-trans back bone
(c) cis-syn-trans-syn-trans back bone
(d) trans-anti-cis-anti-cis back bone
48. In the stable conformation of 5 -pregnane
(a) Rings A, B, C are in boat conformation
(b) Rings A and B are in boat while C in chair conformation
(c) Ring A is in boat while Band C in chair conformation
(d) All the three rings are in chair conformation
49. In case of hypothyroidism, the preferred thyroid preparation is
(a) Levothyroxine
(b) Dextrothyroxine
(c) Leothyroxine
(d) None of the above
50. D-Fructose on simple reduction gives
(a) L-Fructose

(b) Only Sorbitol

(c) Mannitol
(d) Mixture of Mannitol and Sorbitol
51. The structure of a drug having an asymmetric centre is following structure.

Using the IUPAC system, this configuration will be

(a) R (b) S (c) (d)
52. Cryoscopic method is familiar in calculations of isotonic solutions. This
method is based on
(a) Freezing point depression of the drug
(b) Molecular concentration of the drug
(c) pH of the drug
(d) None of the above
53. Biological role of thiamine is because of facile formation of
(a) Thiamine hydrochloride (b) Thiamine pyrophosphate
(c) Thiamine sulphate (d) none of the above
54. Highly sensitive semi quantitative method of detecting microbial antigen in
biological
fluid is done by
(a) Radio immuno electrophoresis
(b) Counter immuno electrophoresis
(c) H.P.L.C
(d) Freeze dried centrifugal method
55 The glass electrode used in pH measurements is
(a) Metal-metal oxide electrode
(b) Membrane electrode
(c) Ion selective electrode
(d) None of the above
56. In phenonthiazine tranquillizing agents, replacement of C-2 hydrogen by
chlorine?
(a) Decreases activity
(b) Increases activity
(c) Activity unaffected
(d) Leads to decreased penetration into the CNS
57. Aminophylline solutions on exposure to air may develop
(a) Crystals of theophylline
(b) Precipitate of aminophylline
(c) Precipitate of ethylenediamine
(d) Straw colour
58. The hypotensive effect of clonidine is due to its action on
(a) -adrenergic receptor
(b) adrenergic receptor
(c) H2 receptor
(d) H1 receptor

59. Sodium nitroprusside is one of the most potent blood-pressure lowering

drugs.
Its use is limited because of
(a) Its short duration of action
(b) Very long duration of action
(c) Ineffective of oral route
(d) None of the above
60. Cocaine is a mono acid tertiary base which on treatment with hot dilute acids
gives?
(a) Ecogonine, methyl alcohol and scopic acid
(b) Ecogonine, methyl alcohol and cinnamic acid
(c) Ecogonine, methyl alcohol and benzoic acid
(d) Ecogonine, ethyl alcohol and benzoic acid
61. Which one is true synonym of Withania somnifera?
(a) Poison gooseberry
(b) Winter cherry
(c) Indian ginseng
(d) All above
62. The IUPAC nomenclature of the sulindac analogue is:
(a) (Z)-5-Fluoro-2-methyl-1-phenylmethylene-1H-indene-3-acetic acid
(b) (E)-5-Fluoro-2-methyl-1-phenylmethylene-1H-indene-3-acetic acid
(c) 5-Fluoro-2-methyl-1-phenylmethylene-1H-indene-3-aceticacid
(d) (R)-5-Fluoro-2-methyl-1-phenylmethylene-1H-indene-3-aceticacid
63. The Hemiacetal form of aldosterone is between
(a) C-11, -hydroxyl and C-20 carbonyl
(b)C-11, -hydroxyl and C-21 hydroxy
(c) C-11, hydroxy and C-18 carbonyl
(d)C-21, hydroxyl and C-20 carbonyl
64. Surfactants are characterized by the presence of
(a) Water solubilizing and fat solubilizing groups in the same molecule
(b) Only negative charges
(c) Only positive charges
(d) None of the above
65. Acetous perchloric acid solution a common titrant in non-aqueous titrimetric
is
Standardized by
(a) Standard alcoholic KOH solution
(b)N/10 Potassium permanganate
(c) Potassium hydrogen phthalate solution in glacial acetic acid
(d) Mercuric acetate in glacial acetic acid
66. NBRC is located at which place?
(a) Manipur
(b) Manesar
(c) Kanpur
(d) Moradabad
67. Triamcinolone is
(a) 9 -Fluoro-16 -hydroxy prednisolone
(b) 9 -Fluoro-16 hydroxy prednisolone
(c) 9 -Fluoro-16 hydroxy prednisolone
(d) 9 -Bromo-16 hydroxy prednisolone
68. The active metabolite of anti-cancer cyclophosphamide is:
(a) N - hydroxyl cyclophosphamide

(b) N methyl cyclophosphamide

(c) 4 hydroxyl cyclophosphamide
(d) N acetyl cyclophosphamide
69. Mebendazole, an anthelmintic drug, has one group at 5-position in the
benzimidazole structure. It is
(a) S CH2 CH2 CH3
(b) S Ph
(c) Ph SO2
(d) Ph - CO
70. Sedative action of barbiturates is due to substituents at C it is due to?
(a) High lipophilicity of groups at C position
(b) Electronic withdrawing effect
(c) Steric effect
(d) Metal chelation
71. Sterility test for the materials meant for surgical suture requires incubation
for?
(a) 7 days
(b) 14 days
(c) 21 days
(d) 28 days
72. Silver-Silver chloride electrode consists of
(a) Silver wire coated with calomel
(b) Silver wire coated with potassium chloride
(c) Silver wire coated with silver chloride
(d) Platinum wire coated with silver chloride
73. Extinction E equal to?
(a) Log 0 /
(b) Log T
(c) It / Io
(d) Io. 10-ct
74. Senna leaf I.P. consists of
(a) Dried leaflets of Cassia acutifolia and Cassia angustifolia
(b) Dried leaflets of Cassia indica
(c) Dried leaflets of Cassia carpinifolia
(d) Dried leaflets of Cassia carpinifolia and Cassia acutifolia
75. Conformational isomerism is:
(a) cis-trans isomerism
(b) Optical isomerism
(c) Dextro-and levo-rotatory
(d) Non-identical spatial arrangement of atoms in molecules resulting from rotation
about one
or more simple bonds
76. According to pH partition theory, a weakly acidic drug will most likely be
absorbed
From the stomach because the drug which exist primarily in the
(a) Un-ionised, more lipid soluble form
(b) Ionised, more water soluble form
(c) Form of weak acid and more soluble in acid media
(d) Ionic form of the drug which facilitates diffusion
77. A mixtureofhydrochloricacidandaceticacidcanbetitratedsatisfactorily by
(a) Potentiometry
(b) Conductometry

(c) Amperometry
(d) Spectrophotometry
78. Natural Camphor is:
(a) An optically inactive aldehyde obtained from Cinnamomum camphora
(b) A white dextro rotatory ketone obtained from the wood of Cinnamomum camphora
(c) A white optically inactive ketone obtained from the bark of Cinnamomum camphora
(d) A white volatile aldehyde obtained from the bark of Cinnamomum camphora
79. Which of the following steroids shows predominant mineralocorticoid action?
(a) Hydrocortisone
(b) Spironolactone
(c) Dexamethasone
(d) Fludrocortisone
80. As per G.M.P. permitted limit of solid contents in water for injection is?
(a) 100ppm (b) 1.0 ppm
(c) 0.1 ppm (d) 10.0 ppm
81. Which of the following is a microsomal enzyme inducer?
(a) Indomethacin (b) Clofibrate
(c) Tolbutamide (d) Glutethamide
82. Fiducial limit is a term used in
(a) Microbiological assay
(b) Biologically assay
(c) Chemical assay
(d) Instrumental methods of assay
83. Phenothiazines are metabolized
(a) In the hepatic microsomal system by hydroxylation followed by conjugation with
glucoronic acid
(b) In the liver by oxidation
(c) In the hepatic microsomal system by reduction
(d) In the hepatic microsomal system by oxidation followed by conjugation with glycine.
84. Benzodiazipines potentiate
(a) The binding of protein to nervous tissue
(b) The binding of GABA to liver
(c) The binding of GABA to receptors
(d) The binding or GABA to carbohydrates
85. Enkephalins are
(a) Exogenous compounds useful in Analgesia
(b) Endogenous ligands which are pentapeptides that are localized in some nerve
endings.
(c) Endogenous ligands which are tripeptides that are present in nervous tissue
(d) Endogenous ligands which are tetrapeptides that are present in cardiovascular
tissue.
86. Benorylate is a Prodrug, chemically it is polymeric condensation product of?
(a) Aluminium oxide and asprin
(b) An acetyl salicylic ester of phenol
(c) An acetyl salicylic ester of paracetamol
(d) An acetyl salicylic ester of -naphthol
87. Acetonides are prepared to improve the bioavailability of certain drugs. Which
of
the following is available as acetonide?
(a) Clonidine
(b) Prednisolone
(c) Pyrimethamine

(d) Tramicinolone
88. Which one of the following indicators is used in Complexometric Titration?
(a) Crystal Violet
(b) Murexide
(c) Eosin
(d) Methyl Orange
89. Betamethasone is:
(a) 9 Fluro 11 , 17 , 21 trihydroxy16 methyl pregna-1, 4 diene3, 20 Dione
(b) 9 Fluro 12 , 13 , 21 trihydroxy17 methyl pregna-1, 4 diene3, 20 Dione
(c) 9 Fluro 11 , 17 , 21 trihydroxy16 methyl estra-1, 4 diene3, 20 dione
(d) 9 Fluro 11 , 17 , dihydroxy16 methyl pregna-1, 4 diene3, 20 Dione
90. One of the drug is excreted primarily by renal tubular sections. Identify.
(a) Gentamycin (b) Kanamycin
(c) Tetracycline (d) Carbenicillin
91. Identify one of the cancer chemotherapeutic agent which is an antimetabolite?
(a) Flurouracil (b) Nitrogen mustard
(c) Cyclophosphamide (d) Chlorambucil
92. Agents useful in the treatment of bronchial asthma usually
(a) Block both alpha and beta adrenergic receptors
(b) Stimulate alpha receptors but block beta receptors
(c) Stimulate beta receptors but block alpha receptors
(d) Stimulate alpha and/or beta receptors
93. The antiarrhythmic drug Quinidine is:
(a) D Stereoisomer of Quinine
(b) L Stereoisomer of Quinine
(c) Racemic mixture of Quinine
(d) None of the above
94. Licence for wholesale of drugs specified in schedule C and C are issued in
form 1
(a) 20 A (b) 20 B
(c) 21 B (d) 22 A
95. The principal constituents Anethole (50-60%) and Fenchone (18-20%) are
present
in the volatile oil obtained from
(a) Fruits of Ammi visnaga Linn
(b) Fruits of Foeniculum capillaceum G (G. vulgare)
(c) Fruits of Carum carvi Linn
(d) Fruits of Anethum graveolens Linn
96. Caffeine on oxidation with KClO /HCl gives
(a) Trimethyl alloxan and urea
(b) Methyl alloxan and dimethyl urea
(c) Diemthyl alloxan and methyl urea
(d) None of the above
97. One of the following types of adverse drug reactions is not believed to be
dose related
phenomena?
(a) Side effects and toxic reactions
(b) Toxic reactions and hypersensitivity
(c) Side effects and hypersensitivity
(d) Hypersensitivity and idiosyncracy
98. 1.12 Gelatin and glycerin are used for the preparation of lamellae in a
specified

ratio. Identify the correct ratio

(A) 1: 1 (b) 5: 1
(B) 9: 1 (d) 10:1
99. One of the following general characteristics is not true for alkaloids?
(a) Nitrogen in the hetrocyclic nucleus
(b) Good solubility inorganic solvents
(c) pK less than 7
(d) Exhibit optical activity
100. Silver/Silver chloride electrode consists of
(a) Metallic silver coated with a layer of silver chloride
(b) Polished platinum wire coated with silver chloride
(c) Silver wire dipped in a saturated solution of silver chloride
(d) Two electrodes one of silver and other of silver chloride
101. In gel permeation chromatography molecules are separated on the basis of
their
(a) Chemical nature
(b) Size and shape
(c) Adsorptive properties
(d) Partition coefficient
102. According to Pauli Exclusion Principle, spins of two electrons in the same
orbital are
(a) parallel to one another
(b) Perpendicular to one another
(c) opposite to one another
(d) Supporting one another
103. Vaccines and toxoids are precipitated and absorbed on to aluminium
hydroxide or
other suitable media. This process results in a dosage form that in comparison to
fluid forms
(a) More effective orally
(b) Absorbed slowly
(c) Stability is increased
(d) Irritation is lost
104. In order to produce characteristic pharmacological action, a drug must
always
(a) Reach high blood vessels
(b) Absorbed from GIT readily
(c) Achieve adequate concentration at the site of action
(d) Excrete unchanged in urine.
105. The first hydrolytic product of STREPTOMYCIN with methanolic hydrochloric
acid is given below. Identify the correct one.
(a) Streptidine +Streptose+N-methyl glucosamine
(b) Streptidine+methyl strepto-biosaminide dimethyl acetal
(c) Streptamine +Streptose+N-methyl glucosamine
(d) Streptamine +Steptosedimethyl acental + N-methyl glucosamine
106. One of the following drugs interferes with cellular metabolism, especially the
synthesis of Mycolic acid. Identify.
(a) Chloramphenicol
(b) Pyrazinamide
(c) Isonicotinic acid hydrazide
(d) Nicotinamide

107. Which of the following is low calorie sweetner use in pharmaceutical

formulation?
(a) Saccharin
(b) Aspartame
(c) Cyclamate
(d) Sorbitol
108. Listed below are structures of some drugs. One of them prevents the
incorporation
of PABA into Folic acid. Identify

109. In Quantitative T.L.C. radioactive material can be studied by

(a) Visual comparison
(b) Density meter
(c) Gravimetry
(d) Geiger counter
110. One of the following is property of WINTER COLD CREAM:
(a) Protect from sunlight
(b) Emollient
(c) A & B
(d) Anti-aging
111. The wavelength source in N.M.R. spectrometer is
(a) Goniometer
(b) Radio frequency oscillator
(c) High voltage generator
(d) Klystron oscillator
112. Benzathine penicillin is
(a) An equimolecular composition of Amoxicillin+ N. N dibenzyl ethylenediamine
(b) A molecular complexation of Benzyl penicillin + N. N dibenzyl ethylene diamine
(c) A molecular complexation of Cloxacillin +ethylenediamine
(d) Equimolecular proportion of Amoxicillin +ethylenediamine
113. Which of the following commonly available large volume dextrose solution
for
intravenous use is isotonic?
(a) 2.5%W/V (b) 5.0%W/V (c) 10%W/V (d) 20%W/V
114. The term bioavailability refers to the

(a) Relationship between the physical and chemical properties of a drug and the
systemic
absorption of the drug
(b) Measurement of the rat and amount of therapeutically active drug that reaches the
systemic
circulation
(c) Movement of drug into the body tissues over time
(d) Dissolution of a drug in the gastrointestinal tract
115. Among the propellants used in aerosols one of the following is used for
topical Pceutical
aerosols.
(a) Trichloro monofluoromethane
(b)Dichloro difluoro methane
(c) Dichloro tetrafluoro ethane
(d) Propane
116. The principal structural component of the cell wall in bacteria is made up of
(a) Simple protein
(b) Peptidoglycan polymer
(c) Complex polysaccharides
(d) Glycoprotein
117. The Xenobiotics that does not cause nephrotoxicity is
(a) Streptozocin (b) Cisplatin (c) Gentamycin (d) Isoniazid
118. Which of the following function of OPIOID receptors?
(a) Decrease nor adrenaline release
(b) Decrease Dopamine release
(c) Decrease Serotonin release
(d) Decrease Serotonin release
119. Assume that a typical type of Cancer is susceptible to an individual drug.
Listed below
are some therapeutic combination of anti-cancer drugs which are rationale except
one.
Identify It.
(a) Thiotepa and Prednisone
(b) Cyclophosphamide and 6-Mercaptopurine
(c) Doxorubicin and Methotrexate
(d) Chlorambucil and Melphalan
120. Clinically available anticancer agents have one of the underlying mechanism
of action
(a) Improving body defense mechanism
(b) Inhibition of cell wall synthesis
(c) Receptor site blockade of cancer cell content
(d) Cell growth inhibitor
121. Listed below are some of the common Radio nuclides used in Nuclear
Pharmacy
which one is generator produced?
(a) 201Ti (b) 67 Ga
(c) 133Xe (d) 99mTc
122. Listed below are some of the drug intermediates. Choose the correct one for
the
synthesis of Procainamide.
(a) p-nitro benzyl chloride and Diethyl amino ethylamine
(b) p-nitro benzyl chloride and ethyl amino ethylamine

(c) p-nitro cinnamoyl chloride and Diethyl amino ethylamine

(d) p-nitro benzene and Diethyl amino ethylamine
123. Choose the correct name for Digitoxigenin.
(a) 3 , 14 , 16 trihydroxy cardenolide
(b) 3 , 12 , 14 trihydroxy cardenolide
(c) 3 , 14 dihydroxy cardenolide
(d) 1, 3, 5, 11a, 14, 19 -hexahydroxy cardenolide
124. 2, 6-dimethylanilineandchloro acetyl chloride are the starting compounds for
the
synthesis of the following drugs. Choose the correct one.
(a) Lidocaine (b) Prilocaine
(c) Bupivacaine (d) Cinchocaine
125. Hyoscyamine an alkaloid obtained from Atropa belladonna
(a) Readily racemises to atropine with ethanolic alkali. Atropine is Hyoscyamine
(b) Readily disintegrates into atropine with acid solution. Atropine is (-) Hyoscyamine
(c) Readily rearranges into atropine with acid solution. Atropine is (+) Hyoscyamine
(d) Readily racemises to atropine with ethanolic alkali. Atropine.