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Department of Social and Behavioral Health, School of Rural Public Health, Texas A&M Health Science Center, College Station, Texas;
Department of Epidemiology and Biostatistics, School of Rural Public Health, Texas A&M Health Science Center, College Station, Texas; and
c
Department of Health Policy and Management, School of Rural Public Health, Texas A&M Health Science Center, College Station, Texas
Manuscript received October 12, 2010 and accepted December 8, 2010
b
Abstract
Nutrition transition theory attributes increased prevalence of high blood pressure to excess body weight associated with lifestyle
changes in recent decades. We examined the association of changes in self-reported hypertension diagnoses with changes in
body mass index (BMI), health-related behaviors, health status, and social risk factors among older Chinese adults from
1997 to 2006. Data from the longitudinal China Health and Nutrition Survey (CHNS) were analyzed for adults who were
age 60 years and older, had a BMI exceeding 18.6 kg/m2, and reported no diagnosis of hypertension at baseline (n 1928).
Logistic regression models identified factors contributing to staying nonhypertensive or developing hypertension over time.
Approximately 17.8% (n 324) of study participants developed self-reported hypertension, whereas 83.2% (n 1604)
remained without hypertension. Those who stayed overweight or obese or became overweight or obese were more likely to
report a new hypertension diagnosis. Incident diagnoses were also observed among those who developed acute conditions, sustained memory loss, or increased their income, whereas remaining nonhypertensive was more likely among rural residents and
those who became more physically active and quit drinking alcohol. Study findings provided partial support for the nutrition
transition theory whereby changing demographics and lifestyle factors were associated with increases in incident hypertension.
J Am Soc Hypertens 2011;5(1):2130. 2011 American Society of Hypertension. All rights reserved.
Keywords: Hypertension; obesity; lifestyles; older adults.
Introduction
China is experiencing an obesity epidemic paralleling
rapid increases in obesity seen in other parts of the world.
Grant support: The project described was partially supported
by Grant Number 90OP0001/03 from the Administration on
Aging and Grant Number R01HD047143 from the National Institute of Child Health and Human Development. The content is solely
the responsibility of the authors and does not necessarily represent
the official views of Texas A&M University System Health Science
Center School of Rural Public Health or funding agencies.
Conflict of interest: The authors declare no conflict of interest.
*Corresponding author: SangNam Ahn, PhD, MPSA, School
of Rural Public Health, Texas A&M University Health Science
Center, 1266 TAMU, College Station, TX 77843. Tel: 979-8624941; fax: 979-458-4264.
E-mail: snahn@srph.tamhsc.edu
1933-1711/$ - see front matter 2011 American Society of Hypertension. All rights reserved.
doi:10.1016/j.jash.2010.12.001
22
S. Ahn et al. / Journal of the American Society of Hypertension 5(1) (2011) 2130
Methods
Study Population
Data for this study were from the China Health and Nutrition Survey (CHNS). The CHNS is an ongoing longitudinal
survey established in the late 1980s in 9 China provinces and
conducted jointly by the Chinese Academy of Preventive
Medicine and the University of North Carolina at Chapel
Hill.26 As the first nationwide longitudinal study in China,
the CHNS aimed to examine how social and economic
transformation in these provinces affects the health and
nutritional status of Chinese residents.7 The survey used
a multistage, random cluster process to draw a sample
from each province that varied substantially in geography,
economic development, public resources, and health indicators.7 The sample represented approximately 50% of the
Chinese population.27 We used data from participants in
1997, 2000, 2004, and 2006 and included adults who were
aged 60 years and older at baseline, responded to at least 2
survey waves, had a BMI greater than 18.6 kg/m2 at baseline, and reported no diagnosis of hypertension at baseline.
For the purposes of the study, we excluded those who reported having hypertension at baseline (n 375). In this
study, analysis periods ranged by participant; with time 1
being the first survey wave in which the respondent participated and time 2 being the final survey wave in which that
same respondent participated. For this reason, we controlled
for the duration of the respondents participation in the final
model. The final analytic sample size was 1928.
Dependent Variables
Changes in Self-reported Diagnosis of Hypertension.
Participants were asked if they were diagnosed with hypertension in the 12 months preceding each survey period. We
created a variable reflecting change in hypertensive status:
scored 0 if the participants reported no hypertension in the
later survey; 1 if they developed hypertension in the later
survey period. Previous research supports that self-reported
hypertension is a relatively valid tool to assess the hypertensive status of study participants.28,29
Independent Variables
Nutritional Factor
BMI was calculated by dividing weight in kilograms by the
square of height in meters and rounding to the nearest tenth.30
Participants BMI scores were categorized using the World
Health Organization criteria: normal (BMI 18.5 to 24.9
kg/m2), overweight (BMI 25.0 to 29.9 kg/m2), and obese
(BMI 30.0 kg/m2), which led to the development of a binary
variable (ie, normal versus overweight/obese) for the
purposes of this study.31 BMI status was further categorized
S. Ahn et al. / Journal of the American Society of Hypertension 5(1) (2011) 2130
Lifestyle Factors
Physical activity was based on nonleisure physical activity
levels: having no physical activity, or engaging in very light,
light, moderate, heavy, and very heavy physical activity. We
categorized these responses as staying with no physical
activity (scored 0), becoming more active (scored 1),
becoming less active (scored 2), continuing light activity
(scored 3), and continuing moderate or more activity
(scored 4) in the later survey period. Although there are no
previous studies to test reliability or validity on this variable,
several published studies have found it to be significant
predictor of weight.3234 The smoking variable was dichotomized to reflect smoker or nonsmoker status. We categorized
this variable into remaining a nonsmoker (scored 0),
becoming a smoker (scored 1), quitting smoking (scored 2),
and continuing to smoke (scored 3) in the later survey period.
Alcohol followed a similar coding scheme: consuming
alcohol and not consuming alcohol consumption in the past
12 months. We categorized this variable into remaining a nonalcohol drinker (scored 0), becoming an alcohol drinker
(scored 1), quitting alcohol drinking (scored 2), and
continuing to drink alcohol (scored 3) in the later survey
period.
Health-related Factors
Participants were asked to report if they had had any
of the following acute symptoms during the preceding
4 weeks: (1) fever, sore throat, cough; (2) diarrhea, stomachache; (3) headache, dizziness; (4) joint pain, muscle
pain; (5) rash, dermatitis; (6) eye/ear disease; (7) any other
infectious disease; and (8) other noncommunicable
diseases,35 which led to a binary variable (yes or no) for
distribution characteristics. We categorized this variable
into staying with no acute conditions (scored 0), developing
new acute conditions (scored 1), reporting the conditions at
baseline but avoiding acute conditions in the later survey
period (scored 2), and continuing to have acute conditions
(scored 3) in the later survey. Previous research suggests
that limitations in cognitive functioning are associated
with an increased risk of high blood pressure.36,37 In the
present study, cognitive functioning was measured by
a single self-reported question that inquired about memory
status.35,38 Those who responded bad or very bad were
considered to have a possible cognitive impairment.35 For
the analysis, we categorized this variable into remaining
the same (scored 0), deteriorating (scored 1), improving
(scored 2), and remaining deteriorated (scored 3) in the
later survey period.
23
Statistical Analyses
Analyses were conducted with the Stata (version 10)
statistical package (Stata Corp, College Station, TX). Participant characteristics were described first. We next conducted
bivariate analyses using Pearson c2 test or t test to examine
the bivariate relationship between changes in self-reported
diagnosis of hypertension and each change of nutritional,
health-related, lifestyle, and social risk factors. Finally,
a logistic regression model was tested to examine the independent influence of changes in BMI, health-related behaviors, and social risk factors on changes in self-reported
diagnosis of hypertension. Odds ratio estimates and their
95% confidence intervals for regression coefficients are
displayed.
Results
Table 1 shows that approximately 17.8% (n 324) of
study participants developed self-reported hypertension
during the study period, whereas 83.2% (n 1604) did not
report hypertension at any point in the study period. Approximately 7.4% (n 142) of study participants became overweight or obese, 5.9% (n 114) reported moving from
overweight or obese to normal weight, and 19.4% (n
372) stayed overweight or obese. Participants who became
less physically active, became a cigarette smoker, became
an alcohol drinker, developed acute conditions, and reported
a deteriorated memory status were 27.6% (n 531), 5.7%
(n 109), 8.3% (n 159), 28.9% (n 559), and 27.4%
(n 527) participants, respectively. The average duration
24
S. Ahn et al. / Journal of the American Society of Hypertension 5(1) (2011) 2130
Table 1
Characteristics of the study participants (n 1,928) in the China Health and Nutrition Survey*
Hypertension change
BMI change
Smoking change
Alcohol change
Gender
Residence
Education
Income change
Variables
1604
324
1289
142
114
372
648
241
531
124
380
1269
109
206
344
1173
159
264
332
1104
559
138
127
612
527
275
512
916
1012
704
1224
786
618
350
1275
198
47
408
333
626
370
239
360
5.6
(83.2)
(17.8)
(67.2)
(7.4)
(5.9)
(19.4)
(33.7)
(12.5)
(27.6)
(6.4)
(19.8)
(65.8)
(5.7)
(10.7)
(17.8)
(60.8)
(8.3)
(13.7)
(17.2)
(573)
(28.9)
(7.2)
(6.6)
(31.8)
(27.4)
(14.3)
(26.6)
(47.5)
(52.5)
(36.5)
(63.5)
(44.8)
(35.2)
(19.9)
(66.1)
(10.3)
(2.4)
(21.2)
(17.3)
(32.5)
(19.2)
(12.4)
(18.7)
(2.9)
S. Ahn et al. / Journal of the American Society of Hypertension 5(1) (2011) 2130
25
Table 2
Bivariate association between changes in self-reported diagnosis of hypertension and variables of interest (n 1928)
BMI change
Smoking change
Alcohol change
Gender
Residence
Education
Income change
Variables
Developing Hypertension
n (%) or Mean (SD)
P Trend*
1127
114
85
269
510
213
434
101
342
1033
91
180
300
951
137
233
283
970
400
125
109
520
436
237
411
774
830
547
1057
660
519
286
1067
159
36
342
294
506
308
212
284
5.51
162
28
29
103
138
28
97
23
38
236
18
26
44
222
22
31
49
134
159
13
18
92
91
38
101
142
182
157
167
126
99
64
208
39
11
66
39
120
62
27
76
6.12
<.001
Duration of study
participation (years)
(70.7)
(7.2)
(5.3)
(16.9)
(31.9)
(13.3)
(27.1)
(6.3)
(21.4)
(64.4)
(5.7)
(11.2)
(18.7)
(59.3)
(8.5)
(14.5)
(17.6)
(60.5)
(24.9)
(7.8)
(6.8)
(32.4)
(27.2)
(14.8)
(25.6)
(48.3)
(51.8)
(34.1)
(65.9)
(45.1)
(35.4)
(19.5)
(66.5)
(9.9)
(2.2)
(21.3)
(18.3)
(31.6)
(19.2)
(13.2)
(17.7)
(2.87)
(50.3)
(8.7)
(9.0)
(31.9)
(42.6)
(8.6)
(29.9)
(7.1)
(11.7)
(72.8)
(5.6)
(8.0)
(13.6)
(68.5)
(6.8)
(9.6)
(15.1)
(41.4)
(49.1)
(4.0)
(5.6)
(28.6)
(28.3)
(11.8)
(31.4)
(43.8)
(56.2)
(48.5)
(51.5)
(43.6)
(34.3)
(22.2)
(64.2)
(12.0)
(3.4)
(20.4)
(12.0)
(37.0)
(19.1)
(8.3)
(23.5)
(2.79)
<.001
.024
.014
<.001
.096
.146
<.001
.595
.394
.001
.001
26
S. Ahn et al. / Journal of the American Society of Hypertension 5(1) (2011) 2130
Table 3
Logistic regression reporting the effects of changes in status on the development of hypertension among older Chinese adults (n 1738)
Variables
BMI change
Smoking change
Alcohol change
Gender
Residence
Education
Income change
Duration of study
participation (years)
Robust SE
P Trend*
95% CI
1
1.73
2.66
2.51
1
0.57
0.88
1.03
0.77
1
1.13
0.73
0.87
1
0.70
0.54
0.82
1
2.64
0.65
1.30
0.449
0.705
0.429
0.153
0.155
0.287
0.178
0.365
0.195
0.191
0.194
0.132
0.183
0.393
0.224
0.374
.036
<.001
<.001
.036
.473
.907
.249
.709
.244
.521
.202
.012
.385
<.001
.214
.367
1.036
1.583
1.799
0.336
0.625
0.599
0.485
0.598
0.437
0.564
0.410
0.336
0.534
1.974
0334
0.737
2.876
4.472
3.512
0.963
1.244
1.781
1.206
2.129
1.234
1.337
1.207
0.873
1.274
3.538
1.278
2.283
1
1.16
0.96
1.54
1
0.87
1
0.59
1
1.06
0.94
1
0.88
0.69
1.05
1
1.56
1.44
0.71
1.73
1.06
0.216
0.225
0.284
0.156
0.090
0.185
0.213
0.196
0.340
0.194
0.349
0.346
0.227
0.452
0.028
.434
.855
.018
.444
.001
.758
.777
.576
.451
.773
.047
.134
.288
.035
.036
0.803
0.605
1.077
0.615
0.438
0.749
0.601
0.572
0.263
0.736
1.007
0.894
0.381
1.040
1.004
1.668
1.517
2.214
1.238
0.797
1.488
1.463
1.364
1.810
1.512
2.419
2.303
1.331
2.888
1.114
longer (OR 1.06). Conversely, remaining with no selfreported diagnosis of hypertension during the survey period
was more common among those who lived in rural areas
(OR 0.59), became more physically active (OR 0.57),
and quit drinking alcohol (OR 0.54) in the later survey.
Discussion
Study findings provide partial evidence to support nutrition transition theory among these older Chinese adults.
Developing hypertension during the survey period was
S. Ahn et al. / Journal of the American Society of Hypertension 5(1) (2011) 2130
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S. Ahn et al. / Journal of the American Society of Hypertension 5(1) (2011) 2130
Conclusions
To our knowledge, this is the first study to assess the
associations of changes in body composition, healthrelated behaviors, health status, and social risk factors
with changes in hypertensive status in older Chinese adults.
This study found evidence that promoting lifestyle factors
(improved body composition, more active physical activity,
and reduced/eliminated alcohol consumption) can be
important factors in reducing the risk of developing hypertension. Vast opportunities exist for public health interventions to ameliorate these risk factors and foster a healthier
population of aging Chinese.
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