BIOPROCESS ENGINEERING

Spring 2015

Course Description: Bioprocess engineering is the application of engineering principles to

design, develop, and analyze processes using biocatalysts. These processes may result in the
formation of desirable compounds or in the destruction of unwanted or hazardous substances.
The tools of the engineer, particularly the chemical engineer, will be essential to the
successful exploitation of bioprocesses.

The following is a list of units that will be addressed in order that they will be covered
(1st week)

Introduction

1. What is a Bioprocess Engineer?

(2-8 weeks) The Basis of Biology: An Engineers Perspective
2. An Overview of Biological Basics
3. Enzymes
4. How Cells Work
5. Major Metabolic Pathways
6. How cells Grow
7. Stoichiometry of Microbial Growth and Product Formation
8. How Cellular Information is Altered
(8th week last class) Mid Term Exam.
(9-11 weeks) Engineering Principles for Bioprocesses
9. Operating Considerations for Bioreactors for Suspension and Immobilized Cultures
10. Selection, Scale-up, Operation, and Control of Bioreactors
11. Recovery and Purification of Products
(12-16 weeks) Applications to Nonconventional Biological Systems
12. Bioprocess Considerations in using Animal Cell Cultures
13. Bioprocess Considerations in using Plant Cell Cultures
14. Utilizing Genetically Engineered Organisms
15. Medical Applications of Bioprocess Engineering

16. Mixed Cultures

(16th week last class) Final Exam.

Text: The assigned textbook for this course is Bioprocess Engineering, Basic Concept by
Michael L. Shuler/Fikret Kargi, 2nd Edition Prentice Hall PTR, 2002, ISBN 0-13-122857-9

Grading: Course performance and grading will be determined as follows:

1. Mid Term exam (30%)
2. Final Exam (30%)
3. Group Projects (10/each x 4 times, 40%)

Syllabus
Introduction to Semiconductor Process and System Integration
Spring 2015

Course Description:
This course is focused on semiconductor process and system integration technology and process.
This class is one of convergence process and technology and based on the material science,
semiconductor processing and process integration including wafer bonding characteristics,
thinning, patterning and supercontact filling process. The roles of bonding, structure and
composition in influencing and controlling physical properties are discussed. The course
emphasizes physical understanding of semiconductor process through unit process operation,
characterization and analytical method.

Tentative Schedule of Lectures

1st week: Introduction to the semiconductor industry
2nd week: Characteristics of semiconductor materials
3rd week: Device technologies
4th week: Silicon and wafer preparation
5th week: Chemicals in semiconductor fabrication
6th week: Contamination control in wafer fabs
7th week: Metrology and defect inspection
8th week: Gas control in process chambers, Midterm Exam.
9th week: IC fabrication process overview
10th week: Oxidation
11th week: Deposition
12th week: Metallization
13th week: Photolithography: vapor prime to soft bake
14th week: Photolithography: alignment and exposure
15th week: Photolithography: photoresist development and advanced lithography, Final Exam.

Textbook:
Semiconductor Manufacturing Technology by Michael Quirk

Grading Policy:
Midterm: 40%, Final Exam: 40%
Homework: 15%
Class Attendance: 5%

PHYSIOLOGY
Spring 2015
Course Description: This course has been designed to introduce the student to human
physiology. It targets a wide range of students with diverse backgrounds and varying
biological experience. The course takes a systems approach to physiology. Due to the
close interrelationship between structure and function in biological systems, each
functional physiology topic will include a brief overview of anatomic structure. The
physical and chemical laws that are the basis of the physiological process will also be
covered and applications to current biomedical research and clinically relevant situations
will be included.
The following is a list of units that will be addressed in order that they will be covered:
(1st week) Introduction to Physiology
(2nd week) Levels of Organization
1. Organization of the Body
2. Homeostasis: A Central Organizing Principle of Physiology
(3~5 weeks) Basic Cell Processes: Integration and Coordination
3. Molecular Interaction
4. Compartmentation: Cells and Tissues
5. Energy and Cellular Metabolism
6. Membrane Dynamics
7. Communication, Integration, and Homeostasis
(5th week last class) First Quarter Exam.
(6~8 weeks) Control and Regulation:
8. Introduction to the Endocrine System
9. Neurons: Cellular and Network Properties
10. The Central Nervous System
11. Sensory Physiology
12. Efferent Division: Autonomic and Somatic Motor Control
13. Muscle
14. Control of Body Movement
(8th week last class) Second Quarter Exam
(9~11 weeks) Integration of Function
15. Cardiovascular Physiology
16. Blood Flow and the Control of Blood Pressure
17. Mechanics of Breathing
18. Gas Exchange and Transport
19. The Kidneys

20. Fluid and Electrolyte Balance

(11th week last class) Third Quarter Exam
(12~15 weeks) Metabolism, Growth, and Aging
21. The Digestive System
22. Metabolism and Energy Balance
23. The Immune System
24. Reproduction and Development
(16th week) Final Exam
Week numbers are tentative and could be subject to change according to school
events.
Sadly, it is presently beyond the scope of this class to provide in depth physical, hands-on
laboratory exercises. However, example simulated exercises are available through CD
and/or web-based venues associated with the purchase of the textbook.
Text: The assigned textbook for this course is Principles of Human Physiology by Cindy
L. Stanfield, 4th Edition, Benjamin Cummings, San Francisco, 2011
ISBN-10: 0-321-68182-7 | ISBN-13: 978-0-321-68182-9
Additional Materials: During the course, handouts and/or relevant research articles
could be distributed to supplement the text.
The textbook is designed to augment lectures and with exception, quiz and exam
questions will not be directly drawn from it. Readings from the text will be assigned
prior to covering a particular unit. Quiz and exam questions WILL be drawn directly
from lectures, class discussions, handouts, outside readings as specifically noted.
Grading: Course performance and grading will be determined as follows:
1. Quarter exam 4 times ( 20/each x 4 times, 80%)
2. Group Projects 4 times (5/each x 4 times, 20%)