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A.D.A.M. Medical Encyclopedia.
Melanoma
Light-colored skin
Basal cell skin cancer almost never spreads. But, if left untreated, it may grow into surrounding
areas and nearby tissues and bone.
Symptoms
Basal cell carcinoma may look only slightly different than normal skin. The cancer may appear
as skin bump or growth that is:
Pearly or waxy
Flesh-colored or brown
In some cases the skin may be just slightly raised or even flat.
You may have:
Treatment
Treatment varies depending on the size, depth, and location of the basal cell cancer. It will be
removed using one of the following procedures:
Excision cuts the tumor out and uses stitches to place the skin back together.
Curettage and electrodesiccation scrapes away the cancer and uses electricity to kill any
remaining cancer cells.
Surgery, including Mohs surgery, in which skin is cut out and immediately looked at
under a microscope to check for cancer. The process is repeated until the skin sample is
free of cancer.
Radiation may be used if the cancer has spread to organs or lymph nodes or for tumors
that can't be treated with surgery.
Skin creams with the medications imiquimod or 5-fluorouracil may be used to treat
superficial basal cell carcinoma.
Expectations (prognosis)
The rate of basal cell skin cancer returning is about 1% with Mohs surgery, and up to 10% for
other forms of treatment. Smaller basal cell carcinomas are less likely to come back than larger
ones. Basal cell carcinoma rarely spreads to other parts of the body.
You should follow-up with your doctor as recommended and regularly examine your skin once a
month, using a mirror to check hard-to-see places. Call your doctor if you notice any suspicious
skin changes.
Complications
Untreated, basal cell cancer can spread to nearby tissues or structures, causing damage. This is
most worrisome around the nose, eyes, and ears.
Prevention
The best way to prevent skin cancer is to reduce your exposure to sunlight. Ultraviolet light is
most intense at midday, so try to avoid sun exposure during these hours. Protect the skin by
wearing hats, long-sleeved shirts, long skirts, or pants.
Always use sunscreen:
Apply high-quality sunscreens with SPF (sun protection factor) ratings of at least 15.
Look for sunscreens that block both UVA and UVB light.
Apply sunscreen at least 30 minutes before going outside, and reapply it frequently.
Examine the skin regularly for development of suspicious growths or changes in:
Color
Size
Texture
Appearance
Also note if an existing skin sore bleeds, itches, is red and swollen (inflamed), or is painful.
References
1. Habif TP. Clinical Dermatology. 4th ed. St. Louis, Mo: Mosby; 2004:724-735.
2. Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, McKena WG. Clinical
Oncology. 3rd ed. Orlando, Fl: Churchill Livingstone; 2004:449-452.
3. Noble J. Textbook of Primary Care Medicine. 3rd ed. St. Louis, Mo: Mosby; 2001:772773.
4. Neville JA, Welch E, Leffell DJ. Management of nonmelanoma skin cancer in 2007. Nat
Clin Pract Oncol. 2007;4(8):462-469. [PubMed]
5. Eigentler TK, Kamin A, Weide BM, et al. A phase III, randomized, open label study to
evaluate the safety and efficacy of imiquimod 5% cream applied thrice weekly for 8 and
12 weeks in the treatment of low-risk nodular basal cell carcinoma. J Am Acad Dermatol.
2007;57(4):616-621. [PubMed]
Review Date: 2/5/2008.
Reviewed by: Kevin Berman, MD, PhD, Associate, Atlanta Center for Dermatologic
Disease, Atlanta, GA. Review provided by VeriMed Healthcare Network. Also reviewed
by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001827/