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DOI 10.1007/s10552-013-0195-z
ORIGINAL PAPER
Received: 11 October 2012 / Accepted: 20 March 2013 / Published online: 28 March 2013
Springer Science+Business Media Dordrecht 2013
Abstract
Purpose The role of dietary habits in the etiology of
nasopharyngeal carcinoma (NPC) has been extensively
investigated in high-incidence areas, but evidence is scanty
in low-incidence populations. This study aimed to investigate the relationship between NPC risk and a wide range
of food groups in the Italian population.
Methods We conducted a hospital-based casecontrol
study in Italy on 198, histologically confirmed, NPC cases
of Caucasian ethnicity, aged 1876 years. Controls were
594 Caucasian cancer-free patients admitted to general
hospitals for acute conditions. Odds ratios (ORs) and the
corresponding confidence intervals (CIs) were estimated
through logistic regression, adjusting for socio-demographic characteristics, tobacco smoking, alcohol drinking,
and energy intake.
A. Zucchetto C. La Vecchia
Department of Clinical Sciences and Community Health,
Universita` degli Studi di Milano, Milan, Italy
E. Negri C. La Vecchia
Istituto di Ricerche Farmacologiche Mario Negri,
IRCCS, Milan, Italy
L. Barzan
Department of Head and Neck Surgery, Azienda Ospedaliera
Santa Maria degli Angeli, Pordenone, Italy
W. Garavello
Clinica Otorinolaringoiatrica DNTB, Universita` degli Studi di
Milano Bicocca, 20126 Milan, Italy
S. Franceschi
International Agency for Research on Cancer, Lyon, France
E. Vaccher
Division of Medical Oncology A, Centro di Riferimento
Oncologico, IRCCS, Aviano, Italy
M. Montella
Unit of Epidemiology, Istituto Tumori Fondazione Pascale,
IRCCS, 80125 Naples, Italy
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Keywords
Nasopharyngeal carcinoma Dietary habits
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