120 random questions for MCQ

Explanation
Question:The polycystic ovary syndrome

Is associated with markedly elevated serum prolactin

True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Occurs in 20% of women of reproductive age

True

False

Accounts for 20% of cases of anovulatory infertility

True

False

With hypersecretion of LH is associated with a reduced chance of

continuing a pregnancy
True

False

Question:The following are inconsistent with a diagnosis of the polycystic ovary syndrome

Normal ovarian morphology on ultrasound scan

True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

LH:FSH ratio < 2:1

True
Normal body mass index
True
Rapidly progressive virilisation
True

Explanation
Question:The polycystic ovary syndrome is associated with

Increased levels of sex hormone binding globulin

True

False

Decreased levels of biologically active oestradiol

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Increased ovarian production of DHEA-sulphate

True

False

Increased ovarian production of androstendione

True

False

Explanation
Question:In a 24 year old sexually active woman who is not using any contraception, the following are suitable
treatments for acne

Oral tetracycline
True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Cyproterone acetate
True
Isotrentinion
True

Topical benzoly peroxide

True

False

Explanation
Question:With respect to androgen production in the female

Testosterone is the main adrenal androgen

True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Androstendione is the main ovarian androgen

True

False

Androstendione and dehydroepiandrosterone do not have direct

androgenic activity
True

False

Dehydroepiandrosterone sulphate is almost exclusively of

adrenal origin
True

False

Your answer:
True

Correct answer:
True

Question:With respect to androgen activity in the female

Testosterone bound to SHBG is biologically inactive

True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Testosterone bound to albumin is biologically inactive

True

False

Increased 5-alpha-reductase activity may lead to signs of

hyper-androgenism
True

False

Androstendione is converted to testosterone in peripheral tissue

True

False

Explanation
Question:The following ovarian tumours are associated with hyperandrogenism

Sertoli-Leydig cell tumours

True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

Hilus cell tumours

True
Luteomas
True
Yolk sac tumours
True

Explanation
Question:The following drugs are associated with hirsutism

Danazol
True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

Phenytoin
True
Cyclosporin A
True
Norethisterone
True

Explanation
Question:The following drugs can cause hirsutism

Finasteride
True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

Gestrinone
True
Cyproterone acetate
True
Gestodene
True

Explanation
Question:The following drugs are associated with hypertrichosis

Phenytoin
True
Diazoxide

False

Your answer: True

Correct answer: True

True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

Minoxidil
True
Finasteride
True

Explanation
Question:The following drugs have the potential to emasculate the male fetus

Danazol
True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

Cyproterone acetate
True
Finasteride
True
Ethinyl-oestradiol
True

Explanation
Question:With respect to endocrine changes around the time of puberty

LH and FSH levels are elevated in the pre-pubertal woman

True

False

Your answer: Correct

True
answer: False

GnRH levels are elevated in the pre-pubertal woman

True

False

Your answer: Correct

True
answer: False

The increase in pulse frequency and pulse amplitude of LH secretion

occurs initially during sleep at puberty
True

False

Your answer: Correct

True
answer: True

A positive feed-back response of gonadotrophins to rising oestrogen

levels induces ovulation
True

Your answer: Correct

True
answer: True

False

Explanation
Question:The following groups of women with primary amenorrhoea can have children of their own (including
surrogacy)

Kallmans syndrome
True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: False

Rokitanskis syndrome
True
Ovarian agenesis
True

Androgen insensitivity syndrome

True

False

Explanation
Question:The following diagnoses are likely in a 30 year old woman with secondary amenorrhoea and low
gonadotrophin levels

Premature ovarian failure

True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: True

Resistant ovary syndrome

True
Sheehans syndrome
True

Prolactin secreting pituitary adenoma

True

False

Explanation
Question:Anorexia nervosa

Is associated with hypothermia and tachycardia

True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer: True

Your answer:
True

Correct answer: True

Your answer:
True

Correct answer: True

Typically affects women before the age of 25 years

True

False

Is associated with weight loss >25% of original body

weight
True

False

May present with primary amenorrhoea

True

False

Explanation
Question:The following are recognised causes of secondary amenorrhoea

Excessive weight loss

True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Excessive exercise
True

Androgen insensitivity syndrome

True

False

Prolactin secreting adenoma

True

False

Explanation
Question:A 32 year old woman with two children is referred with secondary amenorrhoea. No withdrawal bleed is
induced following oral medroxyprogesterone acetate.

Pre-mature ovarian failure is a likely diagnosis

True

False

Your answer: True

Correct answer: True

Anovulation secondary to the polycystic ovary syndrome is the most likely diagnosis
True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Sheehan?s syndrome is a possible diagnosis

True

False

Serum oestradiol levels are likely to be in the normal pre-menopausal range

True

Your answer: True

False

Correct answer: False

Explanation
Question:Prolactin

Is a polypeptide hormone
True

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Is produced by posterior pituitary lactotrophs

True

False

Is produced by the endometrium

True
Is produced by decidua
True

Explanation
Question:The following conditions are associated with mildly elevated serum prolactin

Stress
True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

Breast stimulation
True

Prolactin secreting macro-adenoma

True

False

Polycystic ovary syndrome

True

Your answer: True

False

Correct answer: True

Question:The following drugs are associated with hyper-prolactinaemia

Opiates
True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

Phenothiazines
True
L-dopa
True
Metoclopramide
True

Question:In a pregnant woman on bromocriptine therapy for a pituitary macro-adenoma

The drug should ideally be taken first thing in the morning

True

Your answer: True

False

Correct answer: False

Ergometrine may safely be administered during the third stage of labour

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: True

Headache may be a side-effect of bromocriptine

therapy
True

False

Breast-feeding is contra-indicated (
True

False

Explanation
Question:Ovarian hyper-stimulation syndrome

Is less likely to increase in severity if pregnancy ensures

True

False

Your answer: True

Correct answer: False

In the mild form occurs in 50% of IVF cycles

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

May result in adult respiratory distress syndrome

True

False

Treatment may include the use of iv dextran

True

False

Explanation
Question:With respect to obstetric out-come following assisted reproduction

Perinatal mortality in singleton pregnancies is similar to that in spontaneous pregnancies

True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
False

The HFEA prohibits the transfer of more than 2 embryos

True

False

The risk of early pregnancy loss is similar to that in natural conceptions

True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer: True

The risk of congenital malformations is increased

compared to the general population
True

False

Explanation
Question:Hyperprolactinaemia is a recognised consequence of the following agents

Chlorpromazine
True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

Phenytoin
True
Amitriptyline
True

Metoclopramide
True

Your answer: True

False

Correct answer: True

Explanation
Question:Features of polycystic ovary syndrome include

Failure of follicular maturation

True

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Elevated serum oestradiol concentration

True

False

Elevated serum androstendione concentration

True
Breast atrophy
True

Explanation
Question:Kallman syndrome

Is due to failure of development of the gonadotrophin cells of the pituitary gland

True

False

Your answer: True

Correct answer: False

Is a recognised cause of secondary amenorrhoea

True

False

Your answer: True

Correct answer: False

Is typically associated with nerve deafness

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Is an X-linked recessive disorder

True

False

Explanation
Question:With respect to thyrotoxicosis in pregnancy

Fetal thyrotoxicosis in a euthyroid woman should be treated by

maternal administration of anti-thyroid drugs plus thyroxine
replacement
True

False

Your
answer:
True

Correct
answer: True

Your
answer:
True

Correct
answer: True

Your
answer:
True

Correct
answer: False

Pregnancy should be avoided for at least 4 months after radio-iodine

treatment
True

False

Neonatal thyrotoxicosis carries a 1% mortality rate if untreated

True

False

In a woman with newly diagnosed thyrotoxicosis, beta-blockers should be continued for the rest of
the pregnancy
True

False

Your
answer:
True

Correct
answer: False

Explanation
Question:Secondary amennorhoea is a recognised feature of

Addison
True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

Down
True
Bulimia nervosa
True

Androgen insensitivity syndrome

True

False

Explanation
Question:Premature ovarian failure

Should be differentiated from the resistant ovary syndrome by ovarian biopsy

True

Your answer: True

False

Correct answer: False

Serum FSH levels greater than 40iu/l indicate permanent ovarian failure
True

Your answer: True

False

Correct answer: False

There is an association with an increased risk of ovarian cancer

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Is associated with an increased risk of myocardial

infarction
True

False

Question:Premature ovarian failure can be diagnosed in a woman aged 35 years

After 12 months of amenorrhoea

True

False

Your answer: True Correct answer: False

On the basis of sustained serum FSH levels above 50iu/l

True

False

Your answer: True Correct answer: True

By finding a monophasic basal body temperature

True

False

Your answer: True Correct answer: False

On the basis of sustained high serum concentration of androstendione

True

False

Your answer: True Correct answer: False

280 random questions for MCQ

Explanation
Question:A 34 year old woman presents at 34 weeks gestation with vaginal bleeding and abdominal pain. Her pulse
is 100bpm and blood pressure 130/70.

An emergency caesarean section should be performed if fetal heart

rate decelerations are present
True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
False

Maternal blood pressure is a good indicator of blood loss

True

False

Renal failure is a possible complication

True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
False

Thrombocytosis is a recognised complication

True

False

Explanation
Question:The following are associated with an increased risk of malignant change in a woman with a molar
pregnancy

Maternal age over 39 years

True

Your answer:
True

Correct answer:
True

False

Your answer:
True

Correct answer:
True

False

Your answer:
True

Correct answer:
False

False

Your answer:
True

Correct answer:
False

False

A woman with blood group A with a partner with blood

group O
True
Partial hydatidiform moles
True
Smoking
True

Explanation
Question:In a woman with choriocarcinoma, the following are associated with a worse prognosis

Age <25 years

True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Choriocarcinoma occurring after a normal pregnancy

True

False

Interval > 12 months between antecedent pregnancy and

chemotherapy
True

False

Blood group O or A
True

Your answer:
True

False

Correct answer:
False

Explanation
Question:Regarding the diagnosis of ectopic pregnancy

Diagnostic laparoscopy has a false negative rate of about 4%

True

False

Your answer:
True

Correct answer:
True

Viable intra-uterine pregnancies are detectable by trans-vaginal ultrasound when serum beta-HCG
levels are 1000iu/l
True

False

Your answer:
True

Correct answer:
False

Single serum progesterone measurements are useful in the diagnosis of ectopic pregnancy
True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Use of colour Doppler can differentiate an incomplete

miscarriage from an ectopic pregnancy
True

False

Explanation
Question:A diagnosis of pregnancy of unknown location

Can be made at HCG levels > 3000iu/l

True

False

Your answer: True Correct answer: False

Should not be made if more than 6 weeks have elapsed after the LMP
True

False

Your answer: True Correct answer: False

Can not be made if HCG levels are rising

True

False

Your answer: True Correct answer: False

Can be managed expectantly if the woman is

asymptomatic
True

False

Your answer: True Correct answer: True

Explanation
Question:The following drugs are absolutely contraindicated in breastfeeding

Heparin
True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

Insulin
True
Warfarin
True
Carbimazole
True

Explanation
Question:In pregnancy complicated by maternal Insulin Dependent Diabetes Mellitus

There is an increased risk of neural tube defect

True

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

There is an increased incidence of Down?s syndrome

True

False

Insulin requirements fall after delivery

True

False

Insulin crosses the placenta and causes fetal hyperinsulinaemia

True

Your answer: True

False

Correct answer: False

Explanation
Question:In pregnancy complicated by maternal Insulin Dependent Diabetes Mellitus

Folic acid 0.4mg should be commenced pre-pregnancy

True

False

The risk of intra-uterine death of the fetus is highest in the last 4

weeks of pregnancy

Your answer:
True

Correct answer:
False

True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Biophysical profile score accurately predicts intra-uterine death

True

False

There is an increased risk of congenital cardiac anomalies

True

False

Explanation
Question:The following are characteristic of the fetal hydantoin syndrome

Cleft lip / palate

True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

Hypertelorism
True

Atrio-ventricular septal defect

True
Broad nasal bridge
True

Explanation
Question:The following are characteristic features of the fetal warfarin syndrome

Nasal hypoplasia
True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

Microcephaly
True
Hydrocephalus
True
Cardiac anomalies

True

False

Your answer: True

Correct answer: False

Explanation
Question:The following are characteristic skin manifestations of normal pregnancy

Palmar erythema
True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

Pemphigoid
True
Vitiligo
True
Spider naevi
True

Explanation
Question:The polycystic ovary syndrome is associated with

Increased levels of sex hormone binding globulin

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Decreased levels of biologically active oestradiol

True

False

Increased ovarian production of DHEA-sulphate

True

False

Increased ovarian production of androstendione

True

False

Explanation
Question:The polycystic ovary syndrome is associated with

Increased ovarian production of testosterone

True

Your answer: True Correct answer: True

False

Increased peripheral conversion of oestrogens to androgens

True

Your answer: True Correct answer: False

False

Unopposed oestrogenic stimulation of the endometrium

True

Your answer: True Correct answer: True

False

Increased risk of insulin dependent diabetes mellitus

True

Your answer: True Correct answer: False

False

Explanation
Question:A 30 year old woman with a previous DVT is planning a pregnancy

If the previous DVT was related to the OCP, antenatal thromboprophylaxis is unnecessary
True

Your answer: True

False

Correct answer:
False

Her risk per day of recurrent VTE is maximal in the

puerparium
True

Your answer: True Correct answer: True

False

Antenatal thromboprophylaxis is recommended if had an

axillary vein thrombosis
True

Your answer: True Correct answer: True

False

She should be advised that if she requires a caesarean section, general anaesthesia would be
recommended
True

Your answer: True

False

Correct answer:
False

Explanation
Question:In a pregnant woman with sickle cell disease, the following are consistent with acute chest syndrome

Pyrexia
True

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: True

Increased white cell count

True

False

Pleurytic chest pain

True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

Tachypnoea
True

Explanation
Question:Recognised features of sickle cell disease complicating pregnancy include

Bone necrosis
True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Increased risk of megaloblastic anaemia

True

False

Increased risk of intra-uterine growth restriction

True

False

Increased incidence of severe pregnancy-induced

hypertension
True

False

Explanation
Question:With respect to thyrotoxicosis in pregnancy

Thyroid enlargement indicates inadequate treatment

True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Mild thyrotoxicosis cannot be distinguished clinically from

normal pregnancy
True

False

Sub-total throidectomy is acceptable treatment in the second trimester

True

False

Your answer:
True

Correct answer:
False

Neonatal hyperthyroidism does not occur if the mother has been euthyroid
True

Your answer:
True

False

Correct answer:
False

Explanation
Question:Gestational diabetes is associated with

An increased risk of diabetes mellitus in the woman in later

life
True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
False

A need for insulin treatment in the majority of cases

True

False

An increased risk of fetal malformations even when adequately treated

True

False

Your answer:
True

Correct answer:
False

False

Your answer:
True

Correct answer:
False

Neonatal hypercalcaemia
True

Explanation
Question:A 25 year old woman with insulin dependent diabetes mellitus is pregnant for the first time.

If she has no secondary diabetic complications and fetal growth is normal, induction of labour is
recommended at 40 weeks
True

False

Your answer: True

Correct answer: False

In the absence of any other complications, delivery in a stand-alone midwifery-led unit may be
appropriate
True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

During labour, capillary blood glucose should be

monitored every hour
True

False

If general anaesthesia is required for delivery, capillary

blood glucose should be measured every 30 minutes

True

Your answer: True

False

Correct answer: True

Explanation
Question:With respect to the treatment of venous thrombo-embolism

Intravenous unfractionated heparin is recommended for massive

pulmonary embolism with cardiovascular compromise
True

Your answer: Correct

True
answer: True

False

Mobilisation should be discouraged in women with deep vein thrombosis as the clot might be
dislodged causing pulmonary embolism
True

Your answer: Correct

True
answer: False

False

If measurement of anti-Xa activity is required, it should be performed 12 hours after injection

True

Your answer: Correct

True
answer: False

False

Routine measurement of anti-Xa activity is recommended in a woman

weighing 45kg
True

Your answer: Correct

True
answer: True

False

Explanation
Question:Turners syndrome

Is associated with an accelerated maturation of lymphatic drainage

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

Your answer: True

Correct answer: False

Is associated with coarctation of the aorta

True

False

Is associated with increasing maternal age

True

False

Is associated with ovarian agenesis

True

Explanation

False

Question:The following are recognised clinical manifestations of the polycystic ovary syndrome

Acanthosis nigricans
False

Your answer: True

Correct answer: True

True

False

Your answer: True

Correct answer: True

True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

True
Obesity

Acne

dRecurrent miscarriage
True

Explanation
Question:In a 30 year old nulliparous woman with obesity and a diagnosis of polycystic ovary syndrome

A glucose tolerance test should be recommended on a yearly

basis
True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Serum lipid profile should be performed

True

False

Metformin can be expected to reduce the risk of developing NIDDM in future

True

False

Your answer:
True

Correct answer:
False

Metformin can be expected to result in increased insulin resistance in the short term
True

False

Your answer:
True

Correct answer:
False

Explanation
Question:Ovarian hyper-stimulation syndrome

Is associated with hypokalaemic acidosis

True

False

Your answer: True

Correct answer: False

Is commonly associated with the use of oral ovulation inducing drugs

True

Your answer: True

False

Correct answer: False

Is commoner in older than younger women

True

Your answer: True

False

Correct answer: False

Should be managed with intravenous frusemide if urine out-put is <20ml/h

True

Your answer: True

False

Correct answer: False

Explanation
Question:The following tumour markers are useful in monitoring the ovarian tumours listed

AFP ? yolk sac tumours

True

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: True

Your answer: True

Correct answer: True

Your answer: True

Correct answer: True

Oestrogen ? granulosa cell tumours

True

False

HCG ? ovarian choriocarcinoma

True

False

Thyroxine ? ovarian terratoma ? struma ovarii

True

False

Explanation
Question:With respect to chemotherapeutic agents used in gynaecological oncology

Cis-platin is more nephro-toxic than carboplatin

True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
False

Cis-platin causes less nausea and vomiting than carboplatin

True

False

Forced diuresis is usually employed during paclitaxel therapy

True

False

Intestinal perforation is a recognised complication of

methotrexate
True

Your answer:
True

False

Correct answer:
True

Explanation
Question:Lichen sclerosus

Should be treated with topical corticosteroids

True

False

Your answer: True Correct answer: True

Is characterised histologically by epidermal hypertrophy, dermal oedema and hyalinisation of

collagen
True

False

Your answer: True Correct answer: False

Is characterised by a sub-dermal chronic inflammatory

infiltrate
True

False

Your answer: True Correct answer: True

False

Your answer: True Correct answer: True

May involve the trunk and limbs

True

Explanation
Question:With respect to Lichen sclerosus

Excision of affected vulval skin is recognised treatment

True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
False

CO2 laser vaporisation is recognised treatment

True

False

There is an association with squamous cell cercinoma of the

vulva
True

False

There is an association with HPV infection

True

False

Explanation
Question:Hereditary non-polyposis colorectal cancer syndrome

Is inherited as an autosomal dominant trait

True

False

Your answer: True Correct answer: True

Is associated with an increased risk of endometrial cancer

True

False

Your answer: True Correct answer: True

Is associated with an increased risk of ovarian cancer

True

False

Your answer: True Correct answer: True

The majority of colorectal cancers occur in the rectum

True

False

Your answer: True Correct answer: False

Explanation
Question:Ovarian thecomas

Are typically benign

True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

Are typically bilateral

True

Characteristically occur before puberty

True

False

Your answer: True

Correct answer: False

Are characteristically associated with endometrial hyperplasia

True

False

Your answer: True

Correct answer: False

Explanation
Question:Adenocarcinoma of the uterus

Metastasises characteristically to the supra-clavicular lymph nodes F

True

False

Your answer:
True

Correct answer:
False

Uterine size is a reliable prognostic indicator F

True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

In stage I disease, the incidence of pelvic lymph node

metastases is about 3%
True

False

Pre-operative treatment with progestogens significantly improves prognosis F

True

Your answer:
True

False

Correct answer:
False

Explanation
Question:A 35 year old woman presents with primary genital herpes at 30 weeks gestation

Pre-term delivery is a known complication

True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

Acyclovir is contraindicated
True

Weekly swabs for viral culture are recommended for the rest of the pregnancy
True

Your answer: True

False

Correct answer: False

There is an absolute indication for caesarean section at 39 weeks gestation

True

Your answer: True

False

Correct answer: False

Explanation
Question:Rubella infection in pregnancy

The Presence of rubella IgG in cord blood confirms congenital infection

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: False

Is caused by a DNA virus

True

False

Can be treated with intravenous acyclovir

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Is associated with IUGR

True

False

Explanation
Question:With respect to parvovirus B19 infection in pregnancy

Erythema infectiosum is the most common clinical presentation

True

Your answer: True Correct answer: False

False

The majority of women presenting with clinical features of parvovirus infection are infectious
True

Your answer: True Correct answer: False

False

Maternal anaemia is a recognised complication in

immuno-compromised individuals
True

Your answer: True Correct answer: True

False

Infection is an indication for pregnancy termination

True

Your answer: True Correct answer: False

False

Explanation
Question:A 30 year old woman has been found to be HIV positive on routine screening at 14 weeks gestation

The woman should be encouraged to inform her sexual partner of

the diagnosis
True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

The woman?s HIV status may be disclosed to a sexual partner if the

woman cannot be persuaded to do so
True

False

The woman?s diagnosis may be disclosed to her next of kin if she cannot be persuaded to do so
True

False

All health-care professionals caring for the woman should be made

aware of the diagnosis

Your answer:
True

Correct answer:
False

True

False

Your answer:
True

Correct answer:
True

Explanation
Question:A 35 year old woman has developed chicken pox at 38 weeks gestation

If she requires a caesarean section because of breech presentation, general anesthesia is recommended
True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Delivery should be considered if she develops pneumonia

complicated by respiratory failure
True

False

If she has active lesions after delivery, breastfeeding is not

contraindicated
True

False

If she requires delivery and has active cutaneous lesions,

epidural anesthesia is preferable to spinal anesthesia
True

False

Explanation
Question:The H1N1 influenza virus

Is a DNA virus
True

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Is inactivated by sun light

True
Is inactivated by soap
True

Does not cause disease in other animal species

True

Explanation

False

Your answer: True

Correct answer: False

Question:Malaria in pregnancy is associated with an increased risk of

Miscarriage
True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: True

Neural tube defects

True
Stillbirth
True

Intra-uterine growth restriction

True

False

Explanation
Question:In a 30 year old woman with severe endometriosis and infertility

Treatment with GnRH agonists for 6 months significantly improves spontaneous pregnancy rates
True

Your answer:
True

False

Correct answer:
False

Ovarian suppression with danazol for 6 months significantly improves spontaneous pregnancy rates
True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Ovarian suppression with medroxyprogesterone acetate for 6

months is ineffective in improving spontaneous pregnancy rates
True

False

Ovulation induction is associated with an increased risk of ovarian hyper-stimulation compared to

women with PCOS
True

False

Your answer:
True

Correct answer:
False

Explanation
Question:With respect to pre-implantation genetic diagnosis

1-2 cells removed from the blastocyst are representative of the rest of the embryo
True

False

Your answer: True

Correct answer: False

Haploid and tetraploid nuclei are rarely found in normal human pre-implantation embryos
True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Up to 50% of normal human pre-implantation

embryos show mosaicism
True

False

Mosaicism makes sexing of the pre-implantation embryo impossible

True

False

Your answer: True

Correct answer: False

Explanation
Question:A 35 year old woman presents to her general practitioner with a 6 months history of urinary incontinence.
The following are indications for referral to hospital

Her symptoms of urinary stress incontinence have not improved after 2 weeks of physiotherapy
True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Her symptoms of urinary stress incontinence have not

improved after 4 months of physiotherapy
True

False

She has a palpable bladder on examination

True

False

She has a 20 weeks size fibroid uterus

True

False

Explanation
Question:With respect to the assessment of pelvic organ prolapse

Stage 0 is prolapse which extends to the level of the hymenal ring

True

False

Your answer: True

Correct answer: False

Stage 1 is when the leading edge of the prolapse is more than 1cm below the level of the hymenal
ring
True

False

Your answer: True

Correct answer: False

Stage 2 includes prolapse with the leading edge 1cm

below the hymenal ring
True

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: True

Stage 4 is when the vagina is completely everted

True

False

Explanation
Question:The following drugs have been shown to have a tocolytic effect

Ritodrine
True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

Terbutaline
True
Misoprostol
True
Mifepristone
True

Explanation
Question:With respect to ovarian function around the time of the menopause

Ovarian inhibin stimulates FSH release

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Ovarian sensitivity to gonadotrophins decreases

True

False

FSH levels are of diagnostic use in a woman with hot flushes

True

False

Your answer: True

Correct answer: False

Peri-menopausal women taking sequential HRT do not require additional contraception

True

False

Your answer: True

Correct answer: False

Explanation
Question:Raloxifene

Relieves menopausal symptoms

True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
False

Is associated with an increased risk of venous thromboembolism

True

False

Stimulates endometrial oestrogen receptors

True

False

Has been shown to significantly reduce the risk of hip fractures

True

False

Your answer:
True

Correct answer:
False

Explanation
Question:The following have been shown to be effective in the relief of vaso-motor menopausal symptoms

Trans-dermal clonidine
True

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Vitamine E supplementation
True
Megestrol
True
Raloxifene
True

Explanation
Question:A rhesus negative woman is 16 weeks into her fifth pregnancy. Her last baby had rhesus disease requiring
exchange transfusion. This pregnancy is by a new partner whose genotype is cde/CDE.

A positive indirect coombs test performed on cord blood indicates an infant affected by rhesus disease

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Fetal haemoglobin concentrations can be estimated from

maternal antibody concentrations
True

False

Maternal antibody level of 4iu/ml should prompt cordocentesis

True

Your answer: True

False

Correct answer: False

Intra-uterine transfusion is recommended if severe fetal anaemia is diagnosed at 34 weeks gestation

True

Your answer: True

False

Correct answer: False

Explanation
Question:Fetal hydrocephalus

Is associated with chromosomal anomalies in less than 15%

of cases
True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
False

Has a causal association with fetal viral infections

True

False

May be a result of the Arnold-Chiari malformation

True

False

Is always the result of obstruction to the flow of CSF

True

False

Explanation
Question:With respect to radiological investigation of the renal tract during pregnancy

Fetal exposure to ionising radiation from intravenous pyelography is

lower in the first trimester compared to the third trimester
True

False

Fetal exposure to ionising radiation from CT scanning of the renal tract

is lower in the third trimester compared to the first trimester

Your
Correct
answer: True answer: True

True

Your
Correct
answer: True answer: True

False

CT scanning is preferred to intravenous pyelography in the

investigation of the maternal renal tract during the third trimester
True

Your
Correct
answer: True answer: True

False

Magnetic resonance urography is preferable to CT scanning in the

investigation of the maternal renal tract in the third trimester
True

Correct
Your
answer: True answer: True

False

Explanation
Question:With respect to the use of contrast media for radiological investigations during pregnancy

Gadolinium-based contrast media are absolutely contraindicated

True

Your answer: True

False

Correct answer: False

Iodine-based contrast media are associated with neonatal hyperthyroidism

True

Your answer: True

False

Correct answer: False

Gadolinium-based contrast media are used for CT scanning

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Iodine-based contrast media are not terratogenic

True

False

Explanation
Question:The following are relative contra-indications to endometrial resection

A 12 week size fibroid uterus

True

False

Your answer: True

Correct answer: True

Failed response to the levonorgestrel releasing intra-uterine system

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: True

Woman desires amenorrhoea

True

False

Dysmenorrhoea
True

Your answer: True

False

Correct answer: True

Explanation
Question:During the repair of perineal trauma following vaginal delivery

The use of vicryl or dexon is associated with more perineal pain compared to catgut
True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

The use of vicryl or dexon is associated with less wound

dehiscence compared to catgut
True

False

Catgut is absorbed more rapidly than vicryl

True

False

Sub-cuticular suture for skin closure is associated with greater short term pain compared to
interrupted suture
True

False

Your answer:
True

Correct answer:
False

Explanation
Question:The ureter

Lies inferior to the uterine artery

True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
False

Your answer:

Correct answer:

Lies superior to the cardinal ligament

True

False

Lies 5cm lateral to the angle of the vagina

True

False

Can be protected by carefully reflecting the bladder during

hysterectomy
True

False

True

True

Explanation
Question:Tachycardia occurring within 12 hours after hysterectomy may be due to

Sepsis
True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: True

Dehydration
True
Poor pain control
True

Excessive intra-operative blood loss

True

False

Explanation
Question:Acute inversion of the uterus

Is a recognised complication of ergometrine administration

True

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
False

False

Your answer:
True

Correct answer:
True

False

Your answer:
True

Correct answer:
False

False

Causes tachycardia and hypertension

True

False

Can be treated by O sullivan?s hydrostatic pressure

manoeuvre
True
May result from placenta acreta
True

Explanation
Question:With respect to breech presentation

ECV is more likely to be successful in Caucasian than in black African women

True

Your answer:
True

False

Correct answer:
False

Meta-analysis has shown that caesarean section is the optimal mode of delivery before term
True

False

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
False

Regardless of mode of delivery, neonatal mortality and

morbidity are higher at a given gestation age than with cephalic
presentation
True

False

10% of fetuses with hydrocephalus present by the breech

True

False

Explanation
Question:The following progestogens are used in formulations of the progesterone-only pill

Medroxyprogesterone acetate
True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

Levonorgestrel
True
Norethisterone
True
Ethynodiol diacetate
True

Explanation
Question:Trichomonas vaginalis

Is a flagellated protozoa
True

False

Strawberry cervix is a classical manifestation

Your answer: True

Correct answer: True

True

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

False

Is associated with increased vaginal pH

True
Is sensitive to metronidazole
True

Explanation
Question:With respect to IUCDs

The GyneFix IUCD is licensed for 8 years

True

False

Your answer:
True

Correct answer:
False

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

The Cu T 380 is licensed for 8 years

True

The Multiload Cu 375 is licensed for 5 years

True

False

A device fitted after the age of 40 years can safely be left in situ
until 1 year after the menopause
True

False

Explanation
Question:The following are essential for a clinical diagnosis of acute PID

Cervical excitation
True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

Adnexal tenderness
True

Offensive vaginal discharge

True

False

A history of unprotected sexual intercourse

True

False

Your answer: True

Correct answer: False

Explanation
Question:The following drugs reduce the efficacy of the levonorgestrel-only post-coital contraceptive

Phenytoin
True

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

Ampicillin
True
Sodium valproate
True
Carbamazepine
True

Explanation
Question:With respect to tubal ligation

Culdoscopy is an acceptable alternative to laparoscopy

True

False

Your answer: True

Correct answer:
False

Culdoscopy is associated with a lower risk of major morbidity compared to laparoscopy

True

False

Your answer: True

Correct answer:
False

Culdoscopy is associated with a higher rate of technical

difficulty than laparoscopy
True

False

Your answer: True Correct answer: True

The Pomeroy technique uses non-absorbable suture to tie the base of a loop of fallopian tube
True

Explanation

False

Your answer: True

Correct answer:
False

Question:With regard to female sterilisation in the UK

Failure is the commonest cause of litigation in

gynaecological practice
True

False

Your answer:
True

Correct answer:
True

It may be performed in an emergency without the woman?s consent

True

False

Your answer:
True

Correct answer:
False

If performed during the luteal phase, uterine curretage reduces the chance of pregnancy
True

False

Your answer:
True

Correct answer:
False

When clips are used, failure more than a year later is typically the result of clip misapplication
True

False

Your answer:
True

Correct answer:
False

Explanation
Question:With regard to intra / extra-cranial haemorrhage

Sub-aponeurotic haemorrhage carries a 15-20% mortality

True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Sub-arachnoid haemorrhage generally carries a poor prognosis

True

False

Tentorial tears are associated with vaginal breech deliveries

True

False

Intra-ventricular haemorrhage maybe an incidental finding in 2%

of normal term babies
True

False

Explanation
Question:With respect to the androgen insensitivity syndrome

Normal breast development occurs

True

Your answer: True

False

Correct answer: True

There is normal development of axillary and pubic hair

True

False

Your answer: True

Correct answer: False

Your answer: True

Correct answer: False

Fertility is possible with ovulation induction

True

False

Secondary amenorrhoea may be the presenting complaint

True

Your answer: True

False

Correct answer: False

Explanation
Question:A 34 year old woman with a history of recurrent DVT has telephoned the hospital because she has missed
her period by 6 days and her pregnancy test is positive. She has been taking warfarin 4mg daily.

She should be asked to see her general practitioner or midwife before 12 weeks gestation
True

False

Your answer: True

Correct answer: False

She should stop taking warfarin immediately and contact her general practitioner as soon as possible
True

False

Your answer: True

Correct answer: False

Termination of pregnancy should be offered because of the terratogenic effects of warfarin

True

False

Your answer: True

Correct answer: False

Vitamin K supplementation should be recommended

True

False

Your answer: True

Correct answer: False

Explanation
Question:The following are high risk factors for developing hypertensive disorders in pregnancy

15 year history of insulin-dependent diabetes mellitus

True

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

Inter-pregnancy interval more than 10 years

True
Pregnancy with a new partner

False

True

False

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: False

Family history of pre-eclampsia

True

Explanation
Question:The following are associated with an increased risk of pre-eclampsia

Protein S deficiency
True

Your answer: True

Correct answer: False

False

Your answer: True

Correct answer: True

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

False

Prothrombin gene mutation heterozygosity

True
Anti-cardiolipin antibodies
True

Acquired activated protein C resistance

True

False

Explanation
Question:The risks of combined oral contraceptive use outweigh the benefits (UKMEC category 3) in the following
circumstances

A 38 year old woman who smokes 5-10 cigarettes per day

True

False

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

Your answer:
True

Correct answer:
True

A 30 year old woman with a history of migraine with aura but who
has not had an attack for 10 years
True

False

A 35 year old woman with a history of breast cancer treated 6 years

ago and no evidence of recurrence
True

False

A 30 year old woman with a history of severe pregnancy-induced hypertension

True

Your answer:
True

False

Correct answer:
False

Explanation
Question:Alpha-fetoprotein

Levels are elevated in viral hepatitis

True

False

Your answer: True

Correct answer: True

Your answer: True

Correct answer: True

Your answer: True

Correct answer: True

Your answer: True

Correct answer: False

Levels are elevated in hepatic cirrhosis

True

False

Is a marker for germ cell carcinoma

True

False

Is a marker for granulosa cell carcinoma

True

False