IV PATHOPHYSIOLOGY

CHOLELITHIASIS

RISK FACTOR
HEREDITY
OBESITY
FEMALE
MULTIPAROUS
AGE OVER 40
FATS

BILE MUST BECOME

SUPERSATURATED WITH
CHOLESTEROL AND CALCIUM

THE SOLUTE PRECIPITATE

FROM SOLUTION AS SOLID
CRYSTALS

CRYSTAL MUST COME

TOGETHER AND FUSE TO
FORM STONES

OBSTRUCTION OF THE SYSTIC

DUCT & COMMON BILE DUCT

JAUNDICE

SHARP PAIN IN THE RIGHT

PART OF ABDOMEN
DISTENTION OF THE GALL
BLADDER

VENOUS AND
LYMPHATIC
DRAINAGE IS

PROLIFERATION
OF BACTERIA

LOCALIZED CELLULAR
IRRITATION OF
INFILTRATION OR BOTH

INFLAMATION OF GALL
BLADDER

AREAS OF ISCHEMIA
MAY OCCUR