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Which of the following are phase I reactions in toxin elimination?

1. biomethylation
2. glucoronidation
3. peroxidase-dependent cooxidation
4. flavin-containing monooxygenase system
5. cytochrome P-450 dependent monooxygenase system

A. 1,2,3
B. 1,3,5
C. 2,3,4
D. 2,3,5
E. 3,4,5

Answer: E pg 418

All of the following are true concerning ultraviolet radiation except:

A. Increased elastin aids in the formation of wrinkles.


B. Exposure to UVA causes apoptosis of keratinocytes in the epidermis.
C. UV radiation results in the formation of pyrimidine dimmers in DNA.
D. Both UVA and UVB cause erythema, pigmentation, and injury to Langerhans
cells and keratinocytes.
E. The acute inflammation of a sunburn is caused by histamine release from
dermal mast cells, IL-1, and synthesis of arachidonic acid metabolites.

Answer: B pg 441-442

All of the following may occur with Vitamin A deficiency except:

A. xeropthalmia
B. corneal ulceration
C. hypoplasia of the epidermis
D. loss of mucociliary epithelium
E. squamous metaplasia of the urinary tract

Answer: C pg 451

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