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Exits of cranial nerves from the skull.[1][9]
Location
Nerve
cribriform plate
Olfactory nerve (I)
optic foramen
Optic nerve (II)
Oculomotor (III)
Trochlear (IV)
superior orbital fissure
Abducens (VI)
Trigeminal V1
(ophthalmic)
Trigeminal V2
Foramen rotundum
(maxillary)
Trigeminal V3
Foramen ovale
(mandibular)
Facial (VII)
internal auditory canal
Vestibulocochlear (VIII)
Glossopharyngeal (IX)
jugular foramen
Vagus (X)
Accessory (XI)
hypoglossal canal
Hypoglossal (XII)
See also: List of foramina of the human body
them carries different functions related to different senses of body. Apart from sensory functions
there are also some that work as motor nerves or mixed nerves. Here is a brief description of 12
cranial nerves.
1. Olfactory
This is a type of sensory nerve that contributes in the sense of smell in human being. These
basically provide the specific cells that are termed as olfactory epithelium. It carries the
information from nasal epithelium to the olfactory center in brain.
2. Optic nerve
This again is a type of sensory nerve that transforms information about vision to the brain. To be
specific this supplies information to the retina in the form of ganglion cells.
. Oculomoter nerve
This is a form of motor nerve that supplies to different centers along midbrain. Its functions
include superiorly uplifting eyelid, superiorly rotating eyeball, construction of pupil on the
exposure to light and operating several eye muscles.
4. Trochlear
This motor nerve also supplies to the midbrain and performs the function of handling the eye
muscles and turning the eye.
5. Trigeminal
This is a type of largest cranial nerve in all and performs many sensory functions related to nose,
eyes, tongue and teeth. It basically is further divided in three branches that are ophthalmic,
maxillary and mandibular nerve. This is a type of mixed nerve that performs sensory and motor
functions in brain.
6. Abducent
This is again a type of motor nerve that supplies to the pons and perform function of turning eye
laterally.
7. Facial
This motor nerve is responsible for different types of facial expressions. This also performs
some functions of sensory nerve by supplying information about touch on face and senses of
tongue in mouth. It is basically present over brain stem.
8. Vestibulocochlear
This motor nerve is basically functional in providing information related to balance of head and sense of sound or hearing. It
carries vestibular as well as cochlear information to the brain and is placed near inner ear.
9. Glossopharyngeal
This is a sensory nerve which carries sensory information from pharynx (initial portion of throat) and some portion of tongue
and palate. The information sent is about temperature, pressure and other related facts.
It also covers some portion of taste buds and salivary glands. The nerve also carries some motor functions such as helping in
swallowing food.
10.
Vagus
This is also a type of mixed nerve that carries both motor and sensory functions. This basically deals with the area of pharynx,
larynx, esophagus, trachea, bronchi, some portion of heart and palate. It works by constricting muscles of the above areas. In
sensory part, it contributes in the tasting ability of the human being.
11.
As the name intimates this motor nerve supplies information about spinal cord, trapezius and other surrounding muscles. It also
provides muscle movement of the shoulders and surrounding neck.
12.
Hypoglossal nerve
This is a typical motor nerve that deals with the muscles of tongue.
These are the 12 cranial nerves that carry many important functions in body.
Function
The cranial nerves provide motor and sensory innervation mainly to the structures within the
head and neck. The sensory innervation includes both "general" sensation such as temperature
and touch, and "special" innervation such as taste, vision, smell, balance and hearing[1][10]
The vagus nerve (X) provides sensory and autonomic (parasympatheic) motor innervation to
structures in the neck and also to most of the organs in the chest and abdomen.[1][3]
Smell (I)
The olfactory nerve (I) conveys the sense of smell.
Damage to the olfactory nerve (I) can cause an inability to smell (anosmia), a distortion in the
sense of smell (parosmia), or a distortion or lack of taste. If there is suspicion of a change in the
sense of smell, each nostril is tested with substances of known odors such as coffee or soap.
Intensely smelling substances, for example ammonia, may lead to the activation of pain receptors
(nociceptors) of the trigeminal nerve that are located in the nasal cavity and this can confound
olfactory testing.[1][11]
Vision (II)
Various deviations of the eyes due to abnormal function of the targets of the cranial nerves
The oculomotor nerve (III), trochlear nerve (IV) and abducens nerve (VI) coordinate eye
movement.
Damage to nerves III, IV, or VI may affect the movement of the eyeball (globe). Both or one eye
may be affected; in either case double vision (diplopia) will likely occur because the movements
of the eyes are no longer synchronized. Nerves III, IV and VI are tested by observing how the
eye follows an object in different directions. This object may be a finger or a pin, and may be
moved at different directions to test for pursuit velocity.[11] If the eyes do not work together, the
most likely cause is damage to a specific cranial nerve or its nuclei.[11]
Damage to the oculomotor nerve (III) can cause double vision (diplopia) and inability to
coordinate the movements of both eyes (strabismus), also eyelid drooping (ptosis) and pupil
dilation (mydriasis).[12][12] Lesions may also lead to inability to open the eye due to paralysis of
the levator palpebrae muscle. Individuals suffering from a lesion to the oculomotor nerve may
compensate by tilting their heads to alleviate symptoms due to paralysis of one or more of the
eye muscles it controls.[11]
Damage to the trochlear nerve (IV) can also cause diplopia with the eye adducted and elevated.
[12]
The result will be an eye which can not move downwards properly (especially downwards
when in an inward position). This is due to impairment in the superior oblique muscle, which is
innervated by the trochlear nerve.[11]
Damage to the abducens nerve (VI) can also result in diplopia.[12] This is due to impairment in the
lateral rectus muscle, which is innervated by the abducens nerve.[11]
The facial nerve passes through the petrous temporal bone, internal auditory meatus, facial canal,
stylomastoid foramen, and then the parotid gland.
Function
The cranial nerves provide motor and sensory innervation mainly to the structures within the
head and neck. The sensory innervation includes both "general" sensation such as temperature
and touch, and "special" innervation such as taste, vision, smell, balance and hearing[1][10]
The vagus nerve (X) provides sensory and autonomic (parasympatheic) motor innervation to
structures in the neck and also to most of the organs in the chest and abdomen.[1][3]
Smell (I)
The olfactory nerve (I) conveys the sense of smell.
Damage to the olfactory nerve (I) can cause an inability to smell (anosmia), a distortion in the
sense of smell (parosmia), or a distortion or lack of taste. If there is suspicion of a change in the
sense of smell, each nostril is tested with substances of known odors such as coffee or soap.
Intensely smelling substances, for example ammonia, may lead to the activation of pain receptors
(nociceptors) of the trigeminal nerve that are located in the nasal cavity and this can confound
olfactory testing.[1][11]
Vision (II)
The optic nerve (II) transmits visual information.[3][10]
Damage to the optic nerve (II) affects specific aspects of vision that depend on the location of the
lesion. A person may not be able to see objects on their left or right sides (homonymous
hemianopsia), or may have difficulty seeing objects on their outer visual fields (bitemporal
hemianopsia) if the optic chiasm is involved.[12] Vision may be tested by examining the visual
field, or by examining the retina with an ophthalmoscope, using a process known as funduscopy.
Visual field testing may be used to pin-point structural lesions in the optic nerve, or further along
the visual pathways.[11]
Various deviations of the eyes due to abnormal function of the targets of the cranial nerves
The oculomotor nerve (III), trochlear nerve (IV) and abducens nerve (VI) coordinate eye
movement.
Damage to nerves III, IV, or VI may affect the movement of the eyeball (globe). Both or one eye
may be affected; in either case double vision (diplopia) will likely occur because the movements
of the eyes are no longer synchronized. Nerves III, IV and VI are tested by observing how the
eye follows an object in different directions. This object may be a finger or a pin, and may be
moved at different directions to test for pursuit velocity.[11] If the eyes do not work together, the
most likely cause is damage to a specific cranial nerve or its nuclei.[11]
Damage to the oculomotor nerve (III) can cause double vision (diplopia) and inability to
coordinate the movements of both eyes (strabismus), also eyelid drooping (ptosis) and pupil
dilation (mydriasis).[12][12] Lesions may also lead to inability to open the eye due to paralysis of
the levator palpebrae muscle. Individuals suffering from a lesion to the oculomotor nerve may
compensate by tilting their heads to alleviate symptoms due to paralysis of one or more of the
eye muscles it controls.[11]
Damage to the trochlear nerve (IV) can also cause diplopia with the eye adducted and elevated.
[12]
The result will be an eye which can not move downwards properly (especially downwards
when in an inward position). This is due to impairment in the superior oblique muscle, which is
innervated by the trochlear nerve.[11]
Damage to the abducens nerve (VI) can also result in diplopia.[12] This is due to impairment in the
lateral rectus muscle, which is innervated by the abducens nerve.[11]
in a horizontal plane.[11] Damage to the cochlear nerve will cause partial or complete deafness in
the affected ear.[11]
damaged, weakness or an inability to elevate the scapula may be present because the levator
scapulae muscle is now solely able to provide this function.[14] Depending on the location of the
lesion there may also be weakness present in the sternocleidomastoid muscle, which acts to turn
the head so that the face points to the opposite side.[1]
A damaged hypoglossal nerve will result in an inability to stick the tongue out straight.
A case with unilateral hypoglossal nerve injury in branchial cyst surgery. [17]
The hypoglossal nerve (XII) is unique in that it is innervated from both the motor cortex of both
hemispheres of the brain. Damage to the nerve at lower motor neuron level may lead to
fasciculations or atrophy of the muscles of the tongue. The fasciculations of the tongue are
sometimes said to look like a "bag of worms". Upper motor neuron damage will not lead to
atrophy or fasciculations, but only weakness of the innervated muscles.[11]
When the nerve is damaged, it will lead to weakness of tongue movement on one side. When
damaged and extended, the tongue will move towards the weaker or damaged side, as shown in
the image.[11]
Exits of cranial nerves from the skull.[1][9]