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Article history:
Received 19 May 2010
Accepted 8 June 2010
Available online 22 June 2010
Background: Inguinal hernia is one of the most common pathologies in the surgical setting. The introduction of the Lichtenstein technique in 1989 (tension-free hernioplasty with polypropylene mesh)
represented one of the most signicant breakthroughs in the treatment of this condition since Bassinis
hernia repair. The aim of this study was to know the most signicant predictive variables of complications in Lichtenstein hernioplasty and if some changes introduced in the technique could reduce these
complications.
Study design: A prospective study of 2002 inguinal hernias in 1592 patients, operated on during 17 years,
using the Lichtenstein tension-free technique for hernia repair with a heavy polypropylene mesh. The
early and late complications and the outcome of modications introduced in the technique over the
study period have all been studied.
Results: The modication in the type of closure reduced the complications rate from 14.4% down to 2.7%.
The introduction of antibiotic prophylaxis reduced the infection rate from 1.2% down to 0.2%.
Conclusions: The most signicant predictive variables of complications in Lichtenstein hernioplasty are
the type of closure, antibiotic prophylaxis, ASA risk and the presence of previous recurrence.
2010 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.
Keywords:
Inguinal hernia
Hernioplasty
Polypropylene mesh
Lichtenstein
Closure
Antibiotic prophylaxis
Infection
1. Introduction
Inguinal hernia is one of the most prevalent pathologies in
surgery consultation. Hernia repair had been attempted on several
occasions throughout medical history with no satisfactory results.1
In 1871 Marcy introduced carbolised catgut sutures to avoid
infections, applying Listers aseptic basis.1 For the next one hundred
years the gold standard surgical technique for hernia repair was
herniorrhaphy as described by Bassini in 1884. Other techniques
were also proposed such as the Halsted, Mc Vay or the Shouldice
techniques; however, all presented the common problem of tension
along the suture line.
In 1958 Usher and Wallace introduced the polypropylene mesh,
which was the rst prosthesis compatible with human tissue, even
in the presence of infection.1
The big breakthrough in hernia repair surgery came with the
application of the tension-free repair by means of a prosthetic mesh
described by Lichtenstein in 19862 for all types of hernias. In 1989
Lichtenstein published his results of 1000 cases with nearly no
recurrences (practically nil according to the author), with a 5-year
* Corresponding author. Hospital Alt Peneds, c/Espirall s/n, 08720 Vilafranca del
Peneds, Barcelona, Spain. Tel.: 34 938180440; fax: 34 938180453. .
E-mail address: 27798ejr@comb.cat (E. Just).
1743-9191/$ e see front matter 2010 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.
doi:10.1016/j.ijsu.2010.06.006
463
2.2. Follow up
Follow up visits were carried out at 1 day, at 15 days, at 3
months, and at 1 year. Early local complications such as seroma,
haematoma, infection, rejection and orchitis, as well as late
complications such as chronic inguinal pain, testicular atrophy and
recurrence, were all directly collected by each surgeon at the time
of the visit using a standardized protocol. General medical
complications related to the actual surgical procedure such as
urological, cardiac, neurological, pulmonary and vascular complications were also assessed. A wound was considered to be infected
if it met any of the CDCs criteria for SSI 199214 with no differentiation between supercial and deep infection. All other complications were also described in the protocol to unify criteria. Hernias
were classied as direct, indirect and mixed, and also according to
the Nyhus anatomical classication as type I, II, III (A, B), and
recurrent IV (A, B).15 The epidemiology of inguinal hernia and the
factors that might inuence its onset were also included in the
study. In 2007 we decided to stop the prospective collection of data
and evaluate the results.
2.3. Statistical analysis
The SPSS v17.0 statistics programme was used to describe each
of the clinical and health care variables of the patients as well as the
procedures included in the study. Once the values of the different
variables were veried to be normally distributed, a bivariate
description analysis was carried out. The X2 test was used for
qualitative variables and the Student t test was used for quantitative
variables, which enabled us to establish a relationship between
both types of variables. If the values of the quantitative variables
were not assumed to be normally distributed, the Wilcoxon T test
and the Mann and Whitney U test were used.
Bivariate analysis allowed us to establish the different associations among the tested variables. Variables found to be signicant
were used to construct a prediction model in which the dependent
variable was the complication of the surgical wound and the
independent variables were the type of closure and the administration of antibiotic prophylaxis, among other complications.
Hypothesis contrasts with a probability of error below 5%
(p < 0.05) were accepted.
3. Results
116 patients (5.86%) developed non-surgical complications
within 30 days after surgery. The mean age of these patients was 7
years more (p < 0.05) than that of patients who presented surgical
complications. The most common non-surgical complication was
acute urine retention (77%).
52 patients (2.6%) had emergency surgery, their age being
signicantly higher (9 years) than that of patients scheduled to
undergo elective surgery (Student t test, p < 0.05).
1220 (61%) wounds were closed using the 1:3 technique (one
single reabsorbable suture for the three layers) whereas 776
wounds (39%) were closed using the 3:3 technique (2 different
suture lines and skin staples).
In overall numbers, 155 (7.7%) wounds developed complications,
74 of which (3.7%) were haematomas, 44 (2.2%) infections, 27 (1.3%)
seromas, and 10 (0.5%) were complications from other causes.
The mean age of patients with wound complications was
signicantly greater (4.2 years) (Student t test, p < 0.05).
The percentage of complicated wounds also increased signicantly as the ASA score increased. Hence, ASA I patients presented
a 3.7% rate of complicated wounds, ASA II patients an 8.4% and ASA
III patients an 11.2%.
464
Wound complications
Haematoma
Infection
3:3
54
7.2%
16
2.3%
34
4.5%
8
1.2%
644
85.4%
654
95.9%
20
2.7%
4
0.6%
70
4.8%
42
2.9%
1298
90.5%
24
1.6%
1:3
Total
Total
No complications
Table 2
Results yielded by logistic regression analysis to predict complications in the
surgical wound.
Closure 3:3
Recurrence
Antibiotic prophylaxis
Anaesthetic risk
ASA II
ASA III or greater
752
1434
4.16
1.91
0.44
2.4e7.2
1.2e2.9
0.2e0.8
2.63
2.93
1.5e4.6
1.5e5.7
Seroma
682
Odds ratio
Conicts of interest
None declared.
Funding
None declared.
Ethical approval
None declared.
Acknowledgements
The authors thank Pere Roura for statistical support. The
following surgeons also participated in the study: Vicen Villalba,
Juan Parodi and Orlando Heredia.
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