Drug of Choice

Disease/Sympto
m

infeksi

Untuk wet cough

Golongan
Obat

penicillins

Jenis Obat

Amoxicillin
(amoxil, Amoxan)

Formularium

Dosis Dewasa

Tablet/kapsul (125500mg)
Sirup (125250mg/5ml)

Tab/caps 250-500mg

Tab
1 tab 3-4x sehari

Analgesic (nonopioid)
Antipiretic

Paracetamol
(Cetapain,
Farmadol)

Inj (10mg/ml)
Tab (500mg)

Cough & Cold

Preparation

Bromhexine
(Bromifar,
Farmavon)

Caplet/tab (8mg)
Syr 4mg/ml

Tab
1 tab 3-4x sehari
Syr
2 tsp (10ml) 3x sehari

Dosis Anak
(mg/kgBB)
Tab/caps
>20kg 250-500mg
<20kg 20-40mg/kg
Syrp
>8kg 125-250mg
Tab
>12 yr 1 tab
6-12 yr tab
3-5 yr tab
3-4x sehari
Tab
>10 yr 1 tab 3x daily
5-10 yr tab 3x
2-5 yr tab 2x daily
Syr
>12 yr 2 tsp (10ml)
6-12 yr 1 tsp (5ml)
3x sehari

Management of allergic
symptoms eg: perennial
& seasonal allergic
rhinitis, chronic
urticaria.

Antihistamin &
Antiallergic

Cetirizine
(Betarhin,
Capritazin,
Cerinin)

Tab (10mg)

10mg 1x sehari

6-12 yr 5mg ( tab

pagi dan sore)
>12 yr 10mg 1x
sehari

External infections of
the eye & its adnexa
caused by susceptible
bacteria.

Eye AntiInvectives &

Antiseptics

Tobramisin
(Bralifex, Isotic
Tobryne)

Mini dose strip, eye

drop 0.3% (3mg/ml)

1-2 tetes 4jam sekali

1-2 tetes 4jam sekali

Antidepresan &
Antidiuretic

Amitriptyline
(Trillin, Elavil,
Levate)

Depression, including
depression accompany
by anxiety & somatic
symptoms.

Tab 25 mg

Out-patient
Initially 2 tab daily.
In-patient
Initially 1 tab 3-6 times
daily, may be increase
up to 8 tabs daily. Max:
12 tab daily.

Efek Samping
Penting
Anaphylaxis, Anemia,
Diarrhea, Headache,
Nausea, Vomiting,
Rush, hypersensitivity

Kontraindikasi

Hypersensitivity of
penicillins

Hypersensitivity,
allergic reactions,
hypotensi

Severe Hepatocellular
insufficiency

Nausea, diarrhea,
indigestion, kembung,
headache, vertigo,
increased sweating,
skin rash

Gastric ulceration,
trimester pertama
kehamilan: laktasi

Drowsiness, dizziness,
headache, agitation,
dry mouth & GI
discomfort;
hypersensitivity
reactions, including
skin reactions &
angioedema.
Localised ocular
toxicity &
hypersensitivity
including itching,
swelling & conjunctival
erythema
Excessive sweating,
dry mouth,
constipation, dizziness,
nausea, fatigue, skin
rash, hypotension,
urinary retention,
tachycardia.

Hypersensitivity to
cetirizine or
hydroxizine, Lactation,
Pregnancy

Hypersensitivity

Glaucoma

Maintenance: 1-4 tab

daily.
Neurotic,
psychosomatic states,
rheumatic & traumatic
muscular disorders.
Alcohol w/drawal
symptoms, status
epilepticus, pre- & postop conditions

Anxiolytic,
Anticonvulsant

Diazepam
(Valisanbe,
Valium)

Tab 2-10 mg

Tab 2-10mg
3x sehari

Tab
6-14 yr 2-4mg
<6 yr 1-2mg
3x sehari
0.1-0.3 mg/kg daily

Mental disturbance,
drowsiness, amnesia,
dependence; blurred
vision; urinary
retention; resp
depression,
hypotension.

Severe psychoses;
acute narrow-angle
glaucoma; premature
infants or neonates;
acute asthma attacks;
myasthenia gravis. 1st
trimester of pregnancy.

Drowsiness, muscle
weakness, ataxia,
amnesia, depression,
lightheadedness,
confusion,
hallucinations, blurred
vision.

Acute narrow-angle
glaucoma, myasthenia
gravis, acute
pulmonary
insufficiency, phobia &
chronic psychotic
obsessive conditions.
Childn & premature
infants

Anxiety 0.25-0.5 mg 3
times daily. Max: 4 mg
daily in divided doses.

Anxiety, panic disorders

w/ or w/o agoraphobia.

Anxiolytic

Alprazolam
(Actazolam,
Xanax, Zypraz)

Tab (0.25mg, 0.5mg,

1mg)

Panic disorders
Initially 0.5-1 mg at
bedtime or 0.5 mg 3
times daily. May
increase to 1 mg daily
for 3-4 days.

Not Recommended

Elderly or debilitated
patients; severe
hepatic dysfunction
0.25 mg 2-3 times
daily.

FC tab Short-term
management of
moderate post-op pain.
Inj Short-term
management of
moderate to severe
acute post-op pain.

Inflammatory &
degenerative forms of
rheumatism, RA,
ankylosing spondylitis,
osteoarthrosis &
spondylarthritis. Painful

NSAIDs

NSAIDs

Ketorolac
(Toradol, Rativol,
Torasic)

Tab (10mg)
Inj (15mg/ml,
30mg/ml)

Natrium
diklofenak
(Voltaren)

Tab (25mg, 50mg)

Inj
Adult Initially 10 mg IM
or bolus IV, then 10-30
mg 4-6 hrly. Max: 90
mg daily for 2 days.
Elderly Max: 60 mg
daily.

Tab
50mg 2-3x sehari
Mild cases: 75-100mg
daily

Single dose: 0.5

mg/kg IV/IM once;
Max 15 mg
Multiple dose: 0.5
mg/kg IV/IM q6hr; not
to exceed 5 days

3 years: 2-3
mg/kg/day for up to 4
weeks

Dyspepsia, GI pain,
nausea, headache,
diarrhoea, dizziness,
drowsiness, swelling,
edema, inj site pain

Headache, dizziness;
vertigo; GI disorders;
increased
transaminases; rash;
inj site pain, reaction &
induration.

Allergic history. Active

peptic ulcer;
cerebrovascular
disease; haemorrhagic
diatheses, high risk of
haemorrhage or
incomplete
haemostasis; nasal
polyps; angioedema;
asthma,
bronchospasm;
hypovolaemia;
moderate or severe
renal impairment.
Pregnancy & lactation.
Childn <16 yr.
Severe hepatic, renal
or cardiac failure.
Gastric or intestinal
ulcer, bleeding or
perforation. Aspirin- or
other NSAID-induced

syndromes of the
vertebral column.
Nonarticular
rheumatism. Acute
attacks of gout.

asthma, urticaria or
acute rhinitis. Proctitis
(supp). Last trimester
of pregnancy.
Lactation.
UTI Mild to moderate:
250 mg twice daily.
Severe: 500 mg twice
daily.

GIT, urinary tract, resp

tract, bone & joints, skin
& soft tissue infections;
acute gonorrhea, acute
osteomyelitis.

Quinolons

Ciprofloxacin
(Prapoxin,
Baquinor)

Tab (250mg, 500mg)

Resp tract, bones &

joints, skin & soft
tissue infections Mild
to moderate: 500 mg
twice daily. Severe:
750 mg twice daily.
Acute gonorrhea 250
mg daily as a single
dose, dose should not
be <750 mg twice
daily.
GIT infections 500 mg
twice daily.

1 year (PO): 10-20

mg/kg q12hr;
individual dose not to
exceed 750 mg q12hr
for 10-21 days

GI disturbances;
dizziness, headache,
insomnia,
hallucinations, tremor,
tiredness, visual
disturbances; skin
reactions; temporary
increase in liver
enzyme values.

Childn & juvenile

before end of growth
phase. Pregnancy &
lactation.