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ne, lmmune response of the body occurs in two ways, 1. Humoral (antibody mediated) immune response Produces antibodi Reutralise pathogens and toxins found in the blood, 2. Cell mediated immune response ~ destroys celle that are infected with bacteria or viruses. 1. Humoral (antibody mediated) immune response a. Phagocytosis and Antigen prosentation (by macrophages, 2. Engatfnent byendectoss ——Phagoom anton Y Phoplyososne = lysosomes & 6 ° Macrophage 1 5 Killing and Digestion 6 Beestlon of debris and Autigen presentation Fig 14.1 by Membrane processes (pseudopodia or “fake feet’) surround the bacterium. The bacterium is engulfes by the macrophage. &, The bacterium is taken into the macrophage by endocytosis and is contained inside the cell within 2 vacuole called as a phagosome. 4. Lysosomes fuse with hydrolytic enzymes to dig. 5. The bacteria are digested within the phagolysosome. Ho Yacuoles. This is known as antigen processing. .A second vacuole containing some small fragments of the bacterium buds from the main vacuole. The {acuoles fuse with the cell surface membrane. The digested Contents are released from the cell (these jal fragment (antigen) combines with the MHC (Major Histo-compatibilty wiace membrane. The antigen is said to have beon resented on the ‘A2 Biology with Stafford: Unit Four: On the Wild Side Immunity and Forensics / Topic Six Page 79 'wever some bacterial antigens remain in the

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