Aquinas University of Legazpi

College of Health Sciences

(PHARMACY INFORMATICS)
ACTIVITY 1
ICT SKILL ASSESSMENT
19 Name: Alfie Benedict P. Espedido

Date: November 9, 2016 Score___

Objective: Evaluate the basic proficiency in utilizing an alternate source of drug information.
Name of the Drug: LIDOCAINE
IUPAC NAME

DESCRIPTION
2-(diethylamino)-N-(2,6dimethylphenyl)acetamide

SOURCES
https://pubchem.ncbi.nlm.nih.g
ov/compound/lidocaine#section
=Names-and-Identifiers
https://pubchem.ncbi.nlm.nih.g
ov/compound/lidocaine#section
=Names-and-Identifiers

Trade name
Lignopad

Manufacturer
Mundipharma

Xylocaine

AstraZeneca

Enducaine

Oriental Chemical Works

Inc

Accucaine

Asclemed Usa, Inc.

Asthesia

Unichem

https://www.mims.com/philippines
/drug/info/lidocaine/?
type=brief&mtype=generic
https://www.mims.com/philippines
/drug/info/lidocaine/?
type=brief&mtype=generic
http://www.fda.gov.ph/consumerscorner/registered-drugs-2/192018dr-xy30205-192018
http://www.drugbank.ca/drugs/DB
00281
http://www.mims.com/india/drug/i
nfo/asthesia/asthesia
%20cream#Manufacturer

CHEMICAL
STRUCTURE

TRADE
NAMES AND
PRICES

VARIOUS
DOSAGE
FORMS AND
STRENGTHS

ADULT
Infiltration Anesthesia
Percutaneous: 1-60 mL of 0.5-1% solution (5-300 mg total
dose)
IV regional: 10-60 mL of 0.5% solution (50-300 mg total dose)

Peripheral Nerve Blocks

Brachial: 15-20 mL of 1.5% solution (225-300 mg total dose)
Dental: 1-5 mL of 2% solution (20-100 mg total dose)
Intercostal: 3 mL of 1% solution (30 mg total dose)
Paravertebral: 3-5 mL of 1% solution (30-50 mg total dose)
Pudendeal (each side): 10 mL of 1% solution (100 mg total
dose)
Paracervical obstetrical analgesia (each side): 10 mL of 1%
solution (100 mg total dose)

Sympathetic Nerve Blocks

Cervical (stellate ganglion): 5 mL of 1% solution (50 mg total
dose)
Lumbar: 5-10 mL of 1% solution (50-100 mg total dose)

Central Neural Blocks/Epidural

General: 2-3 mL/dermatome for anesthesia
Thoracic: 20-30 mL of 1% solution (200-300 mg total dose)
Lumbar analgesia: 25-30 mL of 1% solution (250-300 mg total
dose)
Lumbar anesthesia: 15-20 mL of 1.5% solution (225-300 mg), or
10-15 mL of 2% solution (200-300 mg total dose)

Dosing Considerations
Use preservative-free preparations for spinal or epidural
anesthesia
May be buffered 9:1 with sodium bicarbonate, to reduce pain on
injection (e.g. remove 2 mL of 1% lidocaine from 20 mL vial, and
add 2 mL of sodium bicarbonate solution to vial)
Maximum dose: 4.5 mg/kg, up to 300 mg lidocaine without
epinephrine; or 7 mg/kg, up to 500 mg lidocaine with
epinephrine

PEDIATRIC
Infiltration

http://reference.medscape.com/
drug/xylocaine-zingo-lidocaineanesthetic-343363

Percutaneous: 4-4.5 mg/kg maximum

IV regional: 3 mg/kg

CLINICAL
INDICATIONS

PREGNANCY
CATEGORY

For production of local or regional anesthesia by

infiltration techniques such as percutaneous injection
and intravenous regional anesthesia by peripheral nerve
block techniques such as brachial plexus and intercostal
and by central neural techniques such as lumbar and
caudal epidural blocks.
Caterogry B

http://www.drugbank.ca/drugs/
DB00281

http://www.mims.com/india/dr
ug/info/lidocaine/?
type=brief&mtype=generic