The present research aims, through the knowledge of information design,
stimulate the adherence to proper treatment medicines, arousing the interest and understanding in the reading of medicine leaflets. Using the methodology of qualitative exploratory study, to the extent that conduct a research about the quality of the design of leaflets of medicinal product, which interferes with and influence on the success of its use on the part of users. Still, it has an applied nature, because it uses a case study of the package leaflet of the medicinal product HUMULIN N - human Insulin, to develop the design following the methodology MD3E (Method of Unfolding in 3 Steps), Flavio Anthero Nunes dos Santos, however, propose a new visual presentation of its elements, in that was applied all concepts studied. It is considered that the present work has solved the problem proposed, because all of the objectives were achieved and the final result is consistent with the original proposal. It is stated that the project can be applied in real life situations, where the manufacturers of drugs could analyze the knowledge of this research and provide consumers with access to information easier and understandable, stimulating the accession to the correct treatment of the drug. And can still serve as a reference for a change in national settlement on the medicine leaflets. Keywords: Medicine leaflets. Information design.