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laucoma affects more than 70 million people worldwide and has been shown to be the second-leading
cause of blindness after cataract. Glaucoma is classied
into primary and secondary glaucoma; there are various
types of primary glaucoma in which the eye does not have
any preexisting disease, the most common being primary
582
This article has been peer-reviewed. Cet article a t valu par les pairs.
Can J Ophthalmol 2009;44:5826
doi:10.3129/i09-104
condence interval (95% CI) were calculated by logistic regression. POAG, PCAG, and PEXG patients and controls
were compared with the F2 test.
2%35,43
Patients
n (%)
F
p value
2046
1802 (88)
477
359 (75) 0.41 (0.320.53)
51.67
<0.001
244 (12)
51.67
<0.001
A
538 (26)
478 (23)
11.4
21.71
0.001
<0.001
B
642 (31)
575 (28)
AB
242 (12)
199 (10)
O
624 (31)
550 (27)
Blood group
ABO (Total)
Rh
Rh
A (Total)
A
B (Total)
B
AB (Total)
AB
O (Total)
60 (3)
67 (3)
43 (2)
O
74 (4)
25 (5)
OR (95% CI)
1.82 (1.142.94)
6.33
0.01
15.75
5.97
<0.001
0.01
2.27 (1.493.46)
14.94
<0.001
0.68
2.62
0.40
0.10
34 (7)
1.51 (0.842.72)
1.87
0.17
15 (3)
0.01
8.14
0.75
0.004
27.28
<0.001
44 (9)
2.71 (1.843.98)
583
Table 2Comparison of the blood group of different types of glaucoma (POAG, PCAG, and PEXG) with controls
Blood
groups
Controls
n (%)
ABO (Total)
POAG
n (%)
PCAG
F
p value
n (%)
OR (95% CI)
PEXG
F
p value
n (%)
OR (95% CI)
F
p value
<0.001
146
126 (86) 0.85 (0.511.43)
0.25
0.61
111
91 (82) 0.61 (0.371.01)
3.09
0.08
244 (12)
78 (35)
<0.001
0.25
0.61
0.08
A
538 (26)
478 (23)
44 (20)
28 (13)
9.03
8.32
0.002
0.003
3.04
3.04
0.27
0.08
60 (3)
16 (7)
0.001
2.17
0.14
B
642 (31)
575 (28)
84 (38)
64 (29)
1.35 (1.011.80)
1.05 (0.771.42)
0.04
0.75
5.8
5.3
0.016
0.02
67 (3)
20 (9)
1.1 (0.412.97)
0.04
1.00
AB
242 (12)
199 (10)
24 (11)
14 (6.5)
0.91 (0.591.42)
0.63 (0.361.09)
0.16
2.64
0.06
0.06
0.80
0.80
43 (2)
10 (4.5)
2.22 (1.114.42)
5.19
0.02
O
624 (31)
550 (27)
68 (31)
36 (16)
74 (4)
32 (15)
Rh
Rh
A (Total)
A
B (Total)
B
AB (Total)
AB
O (Total)
O
2046
220
1802 (88) 142 (65)
OR (95% CI)
4.22
0.1
0.69 (0.230.21)
0.38
0.53
9.69
5.26
0.002
0.002
<0.001
10 (7)
2.17 (1.114.27)
5.14
0.02
0.68
0.10
12 (8)
11 (7)
0.67 (0.371.21)
0.76 (0.411.41)
1.73
0.76
0.18
0.38
1 (1)
0.32 (0.061.86)
1.39
0.23
4 (4)
1.74 (0.644.74)
1.11
0.29
0.36
0.25
0.54
0.62
26 (23)
20 (18)
0.7 (0.451.09)
0.6 (0.370.98)
2.5
4.25
0.11
0.03
0.09
0.75
6 (5)
1.52 (0.663.50)
0.94
0.33
0.90
0.001
3 (2)
6 (4)
1.14 (0.502.61)
Note: POAG, primary open-angle glaucoma; PCAG, primary closed-angle glaucoma; PEXG, pseudoexfoliative glaucoma; OR, odds ratio.
584
6 (5)
1.89 (0.824.38)
2%&%2%.#%3
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