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discomfort
A clinical study presented at Osteoarthritis Research Society International (OARSI)
congress 2007 and published in Current Medical Research and Opinion, Vol. 24, No. 5,
2008, 14851496, shows that the administration of collagen hydrolysate reduces joint
symptoms brought about by mechanical stress. Significant improvement was
demonstrated in the case of the knee, the joint most frequently affected by pain.
In the study, carried out at the Faculty for Nutrition and Sports Nutrition in conjunction with
the Faculty for Orthopedic Surgery and Rehabilitation at Penn State University, USA, 147
students were treated. All the participants of the study suffered from joint symptoms caused
by sporting activity, e.g. stress conditions, injury, post-surgical trauma, limited mobility and
inflammation.
The study was prospective, randomized, placebo-controlled and double-blind. The effects
brought about by the administration of a daily dose of 10 grams of collagen hydrolysate over
a period of 24 weeks on a number of joints were observed. The hip, knee, shoulder, ankle,
wrist and elbow joints as well as neck and back of the participants, otherwise healthy and
active in sports, were investigated. At the beginning of the study and subsequently every six
weeks, changes in various pain parameters were objectively observed by a physician and
subjectively by the participants with the help of a visual analog pain scale. These were then
defined as primary parameters.
effective as from week 18 both in the entire and in the sub-group. This can be so interpreted
that collagen hydrolysate becomes effective with some delay but remains so for the longer
term.
"The clinical data collected show that collagen hydrolysate significantly alleviates the joint
symptoms in persons that pursue active sports. This could well result in an increase in overall
performance", summarized Dr. Klaus Flechsenhar, Head of Medical Research at GELITA
AG. The study confirms already existing clinical data that clearly show the positive influence
of collagen hydrolysate on joint symptoms as well as improved joint mobility.
References:
Current Medical Research and Opinion, Vol. 24, No. 5, 2008, 14851496