Escolar Documentos
Profissional Documentos
Cultura Documentos
Imipenem/Cilastatin (Primaxin)
+ + + + + + 4+ + + +
Meropenem (Merrem)
+ Generally clinically useful Potentially clinically useful Drug of choice
No handout would be complete without its disclaimer This brief summary should not replace clinical judgment. Refer to primary sources for more detailed information. Blah blah blah
From J. Durbin (2000) and The Sanford Guide (2005) Updated 3/6/2006
Clinically Useful Antibiotics -- Non-Beta-Lactams
Organism G+ G+ G- G- G- Enteric G- Pseudomonas Anaerobes
Drug S. aureus Strep H. flu Neisseria M. catarrhalis Oral Gut
(E. coli, Kleb, Strep, Staph,
(non MRSA) B Pneumo Entero B-lac + B-lac - Mening CG B-lac + Prot, etc.) Bacteroides B. fragilis
glycosides
Gentamycin
Amino-
Tobramycin 4+ +
Amikacin
Erythromycin
Macrolides
(Bacteriostatic, mostly used for Legionella, Pertussis, Mycoplasma, Genital Mycoplasma, Chlamydia, Lyme dz; SE include GI upset, phlebitis)
Ciprofloxadin (Cipro)
+/- +/- + + + + 3+
(cartilage damage in baby beagles)
Ofloxacin (Floxin)
Fluoroquinolones
Levofloxacin (Levaquin)
+/- + + + + + 3+
(good for gm+, QD dosing)
Moxifloxacin (Avelox) +/ + + + + + 3+
Gatifloxacin (Tequin) +/- + + + + + 3+
Norfloxadin (Noroxin)
+/- 3+
(UTI and diarrhea use)
Tetracyclines
Tetracycline
Doxycycline (Vibramycin, Doryx) +/ + + + 2+
Minocycline (Minocin)
Vancomycin (Vancocin)
+ + + +/-
(not absorbed PO, good for MRSA and SNA, C. diff)
Clindamycin
Miscellaneous
+ + +
(bacteriostatic, not for endocarditis, not good for SNA, C. diff)
Chloramphenicol (Chloromycetin)
+/- + + +/- + + + 2-3+ + +
(idiosyncratic rare irreversible aplastic anemia, dose-related toxicity causing reversible BM suppression)
No handout would be complete without its disclaimer This brief summary should not replace clinical judgment. Refer to primary sources for more detailed information. Blah blah blah