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Case Study

Re-Launch of HEXGABALIN
BY ABDELRHMAN TANTAWY
Executive Summary

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1. Market Overview
2. RXs Overview
3. SWOT Analysis
4. Market Key Issues & Strategic Imperatives.

Agenda 5. Pricing
6. Source of Business.
7. Brand Vision & Positioning.
8. Key Promotional Messages.
9. Sales Forecast
10.A&P
11.Sales force structure
12.Key Innovative Projects.
13.Calendar of activities.

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1. Market Overview Market Analysis
Pregabalin vs Gebapentin by unit
2,500,000
2,240,812

2,000,000

1,500,000 1,318,411

969,848 963,913
1,000,000 899,620
723,460 764,526 765,706

500,000 374,772
155,785

-
Units Units Units Units Units
Y/2008 Y/2009 Y/2010 Y/2011 Y/2012
(Absolute) (Absolute) (Absolute) (Absolute) (Absolute)
PREGABALIN GABAPENTIN

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1. Market Overview Market Analysis
Pregabalin vs Gebapentin by value
180,000,000

160,000,000 153,071,629

140,000,000

120,000,000
105,627,381
100,000,000

80,000,000 71,940,784

60,000,000
40,459,490 41,204,391 43,702,380 40,403,711
40,000,000 29,594,234 32,249,497
22,135,762
20,000,000

-
LE Sales LE Sales LE Sales LE Sales LE Sales
Y/2008 Y/2009 Y/2010 Y/2011 Y/2012
(Absolute) (Absolute) (Absolute) (Absolute) (Absolute)
PREGABALIN GABAPENTIN

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1. Market Overview Market Analysis
PREGABALIN by unit
2,500,000

293,939
2,000,000
15,230
186,850

314,717
1,500,000
126,348
169,033 133,917
18,096
129,653 298,258
1,000,000 39,301
99,263
0
77,969
13,318
4,662
9,226
0
66,380
0
46,900 421,697
500,000 445,540
366,345
0
8,075
11,817
165,337 449,856
0 258,875 339,556
155,785 189,543
0
Units Units Units Units Units
Y/2008 Y/2009 Y/2010 Y/2011 Y/2012
(Absolute) (Absolute) (Absolute) (Absolute) (Absolute)
LYRICA PREGDIN-APEX PREGAVALEX IRENYPATHIC PAINICA LYROLIN KEMIRICA HEXAGABALIN Others

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1. Market Overview Market Analysis
GABAPENTIN- by unite
2,500,000

2,000,000 3,771
0
22,969 6,697
57,141 0
32,626
98,152
45,160 295
2,169
2,717
17,421
7,445
106,879
460,340 50,913
1,500,000 6,544
405
0
55,674 423,376 318,622
417
0
68,744
333,064
329,848 425,627 357,902 393,159
1,000,000 368,839
324,451

500,000 969,848 963,913 899,620


723,460 764,526

0
Units Units Units Units Units
Y/2008 Y/2009 Y/2010 Y/2011 Y/2012
(Absolute) (Absolute) (Absolute) (Absolute) (Absolute)
GABAPENTIN GAPTIN CONVENTIN
NEURONTIN NEUROGLOPENTIN GABIMASH ADAPTAN
LEPTICURE GABALEPSY GABAPENTIN

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1. Market Overview Sales trend
PREGABALIN by value
2,500,000

2,000,000

1,500,000

1,000,000

500,000

0
Units Units Units Units Units
Y/2008 Y/2009 Y/2010 Y/2011 Y/2012
(Absolute) (Absolute) (Absolute) (Absolute) (Absolute)
LYRICA PREGDIN-APEX PREGAVALEX IRENYPATHIC PAINICA LYROLIN KEMIRICA HEXAGABALIN

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1. Market Overview Sales trend
PREGABALIN by value
2,500,000

2,000,000

This is about 40%


1,500,000
market growth with
1,000,000 indicate special market
500,000
situation we need to
dig more about it
0
Units Units Units Units Units
Y/2008 Y/2009 Y/2010 Y/2011 Y/2012
(Absolute) (Absolute) (Absolute) (Absolute) (Absolute)
LYRICA PREGDIN-APEX PREGAVALEX IRENYPATHIC PAINICA LYROLIN KEMIRICA HEXAGABALIN

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1. Market Overview

Our
Primary Secondary
competitors

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1. Market Overview Top Player Market Share 2012

NEURONTIN
KEMIRICA
2%
LYROLIN 3%
Pregabalin & 4%
PAINICA
Gebapentin 6%

Market shares LYRICA


IRENYPATHIC 34%
value 2012 6%

CONVENTIN
7%

PREGAVALEX
9%

GAPTIN PREGDIN-APEX
11% 18%

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1. Market Overview Top Player Market Share 2012
Pregabalin Defined Market shares value 2012

PREGAVALEX
11%
IRENYPATHIC
8% KEMIRICA
4%
PREGDIN-APEX PAINICA
22% 7%

Other HEXAGABALIN
10% 1%

LYROLIN
5%
LYRICA
42%

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Rx Overview

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2. Rx Overview Prescribers %
Gabapentin Rx by Specialty % Pregabalin Rx by Specialty %

2%2%2% 0%
4% 2%
3%
5%
4%
29%
9% 10%

13%
19% 60%

13% 23%

G.P. ORTHO. IM
NEURO/PSYCH DERM. OTORH. ORTHO. IM G.P.
CARD. SURG. PULM NEURO/PSYCH DERM. CARD.
GYN PULM

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2. Rx Overview Prescribers by disease in %

LYRICA PREGDIN-APEX IRENYPATHIC PREGAVALEX LYROLIN PAINICA HEXAGABALIN Total

-E14 DIABETES MELLITUS E10 32.00 35.94 18.67 18.47 13.06 18.67 2.58 139.39

-M54 OTHER DORSOPATHIES M50 35.26 19.35 16.71 31.40 16.10 16.71 - 135.54

-M48 SPONDYLOPATHIES M45 11.93 9.33 4.20 9.18 11.30 4.20 - 50.14

-M79 OTH SOFT TISSUE DIS M70 9.14 1.91 8.45 9.25 3.38 8.45 - 40.58

-G58 NER/NER RT/PLEX DIS G50 4.81 8.28 5.37 7.58 7.22 5.37 0.62 39.24

-B09VIR INF SK/M MEM LES B00 6.84 8.14 3.68 2.26 4.31 3.68 - 28.90

-G64POLYNE/OTH DIS PERIP G60 7.92 6.92 3.02 1.40 1.67 3.02 - 23.95

-M19 ARTHROSIS M15 4.57 - - - 0.88 - - 5.45

-R69 GEN SYMPTOMS/SIGNS R50 1.67 2.01 - 1.12 - - - 4.80

-M43 DEFORMING DORSOPTHY M40 - - 0.85 2.52 - 0.85 - 4.22

-Q79 CON MLFM MSSKEL SYS Q65 - - - - 2.49 - - 2.49

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3. SWOT Analysis

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SWOT analysis

S W

O T
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SWOT analysis

S 1. Price
2. Availability
3. Well known molecule

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SWOT analysis

1.
2.
Strength Availability
Non Competitive Price
W
3. Brand Establishment
4. Low Prescription Rate

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SWOT analysis

1. Highly growing market


2. Current perception about Pregabalin and
its market growth over other molecules
3. Shifty from Gebapentin to Pregabalin
4. Diversify specialty

O
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SWOT analysis

1. Well established competitors


2. Multiple competitor
3. Smaller packs and less prices

T
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4. Market Key Issues &
Strategic Imperatives.

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Market Key Issues & Strategic Imperatives
Below the main market key issues and strategies:
1. Establish efficacy & credibility
2. Capitalize on having a unique and un-comparable brand
3. Generation and growth of prescriptions in several indications
4. Shape the market of Pregabalin.
5. Being the first option generic brand in Pregablin market

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5. Pricing

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Pricing
There are four main strategies regarding pricing :

Competitive pricing Differentiation pricing

Skimming pricing Penetration pricing

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Pricing
There are four main strategies regarding pricing :

Competitive pricing Differentiation pricing

Skimming pricing Penetration pricing

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Pricing
How can we compare prices with different concentration & number of tablets ??!!

We can use this Equation

Price per tablet (Price / no. tablet )


Prices Index = X 100
Concentration

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Price Index
Price Index
10.00
9.00
8.00
7.00
6.00
5.00
4.00
3.00
2.00
1.00
-

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Pricing
From the price index before we can find that:

1. HEXGABALIN is an average generic brand price.


2. According to the market leader we are about 40% more economic that Lyrica
3. According to PREGDIN-APEX (18% total market share ) we are slightly more expensive
4. We do not have enough high concentrations, low value concentrations

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6. Source of business

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Rx Prescribers %
Gabapentin Rx by Specialty % Pregabalin Rx by Specialty %

2%2%2% 0%
4% 2%
3%
5%
4%
29%
9% 10%

13%
19% 60%

13% 23%

G.P. ORTHO. IM
NEURO/PSYCH DERM. OTORH. ORTHO. IM G.P.
CARD. SURG. PULM NEURO/PSYCH DERM. CARD.
GYN PULM

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Indication %
Indication %

Others
8%
POLYNE/OTH DIS PERIP
5% DIABETES MELLITUS DIABETES MELLITUS
VIR INF SK/M MEM LES 28% OTHER DORSOPATHIES
6%
SPONDYLOPATHIES
NER/NER RT/PLEX DIS OTH SOFT TISSUE DIS
8%
NER/NER RT/PLEX DIS
OTH SOFT TISSUE DIS
VIR INF SK/M MEM LES
8%
POLYNE/OTH DIS PERIP
Others
SPONDYLOPATHIES OTHER DORSOPATHIES
10% 27%

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Source of business
We need to focus on below specialty:

Based on 1. Ortho
2. GPs

RXs
3. Neuro
4. IM

We need to focus on these indications:


1. DIABETES MELLITUS

and indication 2. OTHER DORSOPATHIES


3. SPONDYLOPATHIES
4. OTHER SOFT TISSUE DIS
5. NER/NER RT/PLEX DIS

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7. Brand Vision &
Positioning.

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Vision

To be the generic of choice for neuropathic pain

Build a great credibility approach among doctors

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Mission
For re-launching HEXGABALIN we need different missions and strategies to build our brand
between this big market full of competitors

S3
S S2
Fulfilling
Build the Hitting the
the market
perception competitors
gaps

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Positioning
In this busy market we need to take different approach to enter a market we do
not have a tangible differentiation points, we all had the same molecule and the
same average prices

We need to select and focus on powerful positioning strategy to


enter this market the right way

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Positioning strategies

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Positioning strategies

1st phase (two Q)


We will use this strategy to enter the market in different way to build a powerful perception and
create a good positioning
It is not for sales generation as we will target the unexpected market just for branding

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Positioning strategies

2nd phase (two Q)


We will use this strategy to enter the market in different ways to build a powerful perception
and create a good positioning

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8. Key Promotional
Messages

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Strategy
We will create a universal campaign for neuro specialty, using the same message and materials
for all specialties, then start customizing it for each indication.

1st phase
2nd phase
We will focus on neuro as an
anti-epileptic product 3rd phase
Hitting the competitors in
their main indication,
General neuropathic pain
in Diabetic nephropathy product of choice, with
Ortho customized materials for
each indication

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Strategy
We will create a universal campaign for neuro specialty, using the same message and materials
for all specialties, then start customizing it for each indication.
Gratefully our
honorable
1 phase
st
competitors
2nd phase
Wealready did
will focus on this
neuro as an
anti-epileptic product 3rd phase
step for us Hitting the competitors in
their main indication,
regarding General neuropathic pain
in Diabetic nephropathy
awareness of Ortho
product of choice, with
customized materials for
pregablin and each indication

neuro molecule in
neuropathic cases

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Creative To enter this busy market we need to
catch/different/reminding message.

Idea Differentiate our product from the competitors

Generation Address important customer buying criteria


Highlight key product characteristics

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Creative Marketing message should be :
Meaningful
Idea

Differentiating
Important

Generation

Sustainable
Believable
Credible

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HEXGABALIN
Creative We need a brand name reminding message for 1st
phase market penetration
Idea
Generation

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Creative
Idea
Generation

THE
HEXA

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THE HEXGABALIN
The HEXA reasons why you need to use Hexgabalin
HEXA The HEXA advantages of Hexgabalin
The HEXA indications of Hexgabalin
Etc..

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9. Sales Forcaste

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Sales trend
Estimated 2013 sales
300,000,000
251,517,942
250,000,000
214,300,281
193,475,340
200,000,000
149,329,761 153,071,629
150,000,000
113,145,175 105,627,381
100,000,000
72,708,987 71,940,784
51,729,996 43,702,380
40,459,490 41,204,391 40,403,711 36,363,340
50,000,000 29,594,234 32,249,497
22,135,762

-
LE Sales LE Sales LE Sales LE Sales LE Sales LE Sales
Y/2008 Y/2009 Y/2010 Y/2011 Y/2012 Y/2013
(Absolute) (Absolute) (Absolute) (Absolute) (Absolute) (Estimated)
PREGABALIN GABAPENTIN Total market

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Sales Forecasting - value
We will forecast about 3% total market share for year 2013:

Total market 2013 = 250M LE || Hexgablin = 250M x 3% = 7.5M LE

That means 500% growth over last year

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Sales Forecasting - unit
After analyzing packs sales we found out below:

HEXAGABALIN
CAPS PREGAVALEX
CAP.GEL.HA LARICA PREGDIN-APEX
CAPS
150 RD 300 MG CAPS 50 300 MG 20
MG 30 10 MG 20
CAP.GEL.HA
RD 75 MG CAPS
20 100 MG 20
CAP.GEL.HA
RD 75 MG CAPS
30 150 MG 20 CAPS 75 CAPS 5
CAPS MG 20
CAP.GEL.HA MG 20
75 MG
RD 150 MG
30
20

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Sales Forecasting - unit

The sales of 75mg caps overcomes 150mg by almost double share


The 50mg overtake the 75mg in some brands
Unsuccessful 300mg concentrations due to unknown reasons (needs field
research)
The smaller the pack, the larger the reach

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Forecaster 2013
Price/RS Price/P
Description P TT Jan Feb Mar Qtr. I Apr May Jun Qtr. II Jul Aug Sep Qtr. III Oct Nov Dec Qtr. IV Total

Unit Unit 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 unite

33% 33% 33% 12% 33% 33% 33% 12% 39% 37% 24% 41% 43% 29% 29% 35%
HEXAGABALIN

EGP 2,400 2,400 2,400 7,200 2,400 2,400 2,400 7,200 9,577 8,978 5,986 24,541 9,000 6,000 6,000 21,000 60,000
CAPS 75 MG 30 120.00 84.00

EGP 1,120 1,120 1,120 3,360 1,120 1,120 1,120 3,360 4,469 4,190 2,793 11,452 4,200 2,800 2,800 9,800 28,000
CAPS 150 MG 30 111.00 77.70

3,520 3,520 3,520 10,560 3,520 3,520 3,520 10,560 14,046 13,168 8,779 35,993 13,200 8,800 8,800 30,800 88,000
Total . Sales (units)
1,151,72 1,079,74 1,082,34
288,624 288,624 288,624 865,872 288,624 288,624 288,624 865,872 719,826 2,951,288 721,560 721,560 2,525,460 7,215,600
2 0 0
TotalT. Turnover (LE)

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10. The A&P budget

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A&P budget
We had four main methods to estimate our target

Fixed Same level


percentage as Task Residual
of sales competitors

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A&P budget

Due to market potentiality and our


Same level positioning strategy we need to invest in our
as brand till building our perception, then we
competitors can take % from sales to update our
activities

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11. Sales force structure
Sales force Structure

To calculate sales force structure we need to


calculate number of doctors with their
potentiality in each governor

Based on our phasing criteria we will select


the right specialty.

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Sales force Structure
We will use the below equation to calculate each area potentiality, therefore number of medical
reps will cover it

SEC # of Visits/
class doctors month
A 8 x 11 month
B 4
C 2
# medical reps =
# medical reps visits per year

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12. Key Innovative
Projects.
Key Innovative Projects.
To create a tipping point in our brand we need to make adramatic change in the market
characteristic to gain a noticeable market share

The The HEXA


Chronic user
Concentration indication
trade deal
VS packing project

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13. Calendar of
activities.

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Calendar of activities.
2012
Item January February March April May June July August September October November December Total
New Launches Facelifting Gel Shaving cream -
New aftershave bottle aftershave cologne -
Promotion -

Key Account Buy two get one offer Nothing else campaign 150+Blam offer Instore activ 35,000 gel+balm 35,000

Wholesaler BiC Bundle Nothing else campaign 20,000 Covarage* gel+balm 20,000

Retail BiC Bundle Nothing else campaign 10,000 gel+balm 10,000

El-Koshk BiC Bundle -


Communication -

TV -

Radio 120,000 160,000 280,000

Magazine 30,000 30,000


OutDoors 700,000 700,000

Online 120,000 80,000 200,000


Road Show -

Cairo 102,000 102,000

Summer 50,000 50,000


Total Budget - - - - 240,000 - 312,000 840,000 35,000 - - - 1,427,000

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Thanks for your time

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