Scribd Logo
Fazer o upload

Bem-vindo(a) ao Scribd!

  • Antibiotic Class by Coverage

    Enviado por

    ayy1
    323 visualizações3 páginas
    This document provides an overview of different classes of antibiotics and their coverage of various bacteria. It lists the classes and some representative drugs, organized by whether they primarily provide gram positive coverage, gram negative coverage, atypical coverage, pseudomonas coverage, or anaerobic coverage. It also describes the four generations of cephalosporins based on their expanding gram negative spectrum as the generation number increases.

    Descrição original:

    basic abx coverage by class

    Direitos autorais

    © © All Rights Reserved

    Formatos disponíveis

    DOCX, PDF, TXT ou leia online no Scribd

    Você considera este documento útil?

    Este conteúdo é inapropriado?

    Denunciar este documento
    This document provides an overview of different classes of antibiotics and their coverage of various bacteria. It lists the classes and some representative drugs, organized by whether they primarily provide gram positive coverage, gram negative coverage, atypical coverage, pseudomonas coverage, or anaerobic coverage. It also describes the four generations of cephalosporins based on their expanding gram negative spectrum as the generation number increases.

    Direitos autorais:

    © All Rights Reserved
    Baixe no formato DOCX, PDF, TXT ou leia online no Scribd
    Sinalizar o conteúdo como inadequado
    323 visualizações3 páginas

    Antibiotic Class by Coverage

    Enviado por

    ayy1
    This document provides an overview of different classes of antibiotics and their coverage of various bacteria. It lists the classes and some representative drugs, organized by whether they primarily provide gram positive coverage, gram negative coverage, atypical coverage, pseudomonas coverage, or anaerobic coverage. It also describes the four generations of cephalosporins based on their expanding gram negative spectrum as the generation number increases.

    Direitos autorais:

    © All Rights Reserved
    Baixe no formato DOCX, PDF, TXT ou leia online no Scribd
    Sinalizar o conteúdo como inadequado
    de 3

    ANTIBIOTIC CLASS BY COVERAGE 2.

    Clindamycin
    3. Broad spectrum penicillins
    Gram positive coverage: 4. Quinolones (Gatifloxacin, Moxifloxacin)
    1. Penicillins (ampicillin, amoxicillin) penicillinase 5. Carbapenems
    resistant (Dicloxacillin, Oxacillin) 6. Chloramphenicol
    2. Cephalosporins (1st and 2nd generation)
    3. Macrolides (Erythromycin, Clarithromycin, Atypical coverage:
    Azithromycin) 1. Macrolides (Legionella, Mycoplasma,
    4. Quinolones (Gatifloxacin, Moxifloxacin, and less Chlamydia)
    so Levofloxacin) 2. Tetracyclines (Rickettsia, Chlamydia)
    5. Vancomycin (MRSA) 3. Quinolones (Legionella, Mycoplasma,
    6. Sulfonamide/Trimethoprim (increasing resistance Chlamydia)
    limits use, very expensive) 4. Chloramphenicol (Rickettsia, Chlamydia,
    7. Clindamycin Mycoplasma)
    8. Tetracyclines 5. Ampicillin (Listeria)
    9. Chloramphenicol (causes aplastic anemia so Deciphering Cephalosporins:
    rarely used) 4 generations based on coverage with improving
    10. Other: Linezolid, Synercid (VRE) gram negative coverage as generation number
    increases. (Learn only one oral and one IV drug
    Gram negative coverage: per generation; 4th generation only IV)
    1. Broad spectrum penicillins (Ticarcillin-
    clavulanate, piperacillin-tazobactam) 1st generation (Cefazolin and Cephalexin):
    2. Cephalosporins (2nd, 3rd, and 4th generation) good gram positive coverage, inexpensive,
    3. Aminoglycosides (renal and ototoxicity) and used primarily to treat skin and soft
    4. Macrolides (Azithromycin) tissue infections.
    5. Quinolones (Ciprofloxacin)
    6. Monobactams (Azetreonam) 2nd generation (Cefuroxime): some gram
    7. Sulfonamide/Trimethoprim positive and gram negative coverage,
    8. Carbapenems (Imipenem) expensive, and rarely used as 1st line
    9. Chloramphenicol therapy except sometimes for PID.

    Pseudomonas coverage: 3rd generation (Ceftriaxone): good gram


    1. Ciprofloxacin negative coverage except pseudomonas,
    2. Aminoglycosides long half-life (q24 hr dosing), crosses blood-
    3. Some 3rd generation cephalosporins brain barrier, biliary and renal clearance.
    4. 4th generation cephalosporins
    5. Broad spectrum penicillins 4th generation (Cefipime): good gram
    6. Carbapenems positive (except MRSA) and gram negative
    coverage, including pseudomonas, crosses
    Anaerobic coverage: blood-brain barrier, good for nosocomial
    1. Metronidazole infections.

    Você também pode gostar