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Monoclonal Antibodies in
Cancer Treatment What the
student needs to know
v>
Monoclonal antibody-based treatment of cancer has been established as
one of the most successful therapeutic strategies for both hematologic
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NIB has the suffix nib, that indicates a small-molecule inhibitor of kinase
enzymes. They are as follows:
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MIB is the suffix for protease or proteasome inhibitors. Mibs are small
molecules that work inside cancer cells to slow proliferation and increase
apoptosis. Proteasomes are enzymes found in cells which participate in
regulating cell function and growth. The inhibition of these enzymes can
lead to the death of cancer cells. Bortezomib and Ixazomib for multiple
myeloma.
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-umab (human)
-omab (mouse)
-ximab (chimera)
-zumab (humanized)
MCA
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Tyrosine kinase
Inhibitor
IMATINIB tinib
LENVATINIB tinib
ERLOTINIB tinib
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