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View this article online at: patient.info/medicine/aspirin-to-prevent-blood-clots-micropirin-nu-seals-aspirin

Aspirin to prevent blood clots (Micropirin,

Nu-Seals Aspirin)
For people who have heart or blood vessel disease, taking low-dose aspirin each day can
reduce the risk of heart attack and stroke.

The usual dose is one low-dose aspirin tablet (75 mg) each day.

If you ever suspect that a child has accidentally swallowed some aspirin, contact your doctor
for advice straightaway.

About aspirin to prevent blood clots

Type of medicine An antiplatelet medicine
Used for To prevent clots from forming in blood vessels
Also called Acetylsalicylic acid
Brands include: Micropirin; Nu-Seals Aspirin
Available as Tablets, and soluble (dispersible) tablets

In your blood there are 'sticky' cells called platelets. When you cut yourself, the platelets stick to each other (clot)
to seal the wound. Sometimes platelets stick to each other inside an artery - this is called a thrombus. A
thrombus can block a blood vessel, and this is often the cause of a stroke or heart attack. This is more likely to
happen if the walls of the arteries to your head or heart have areas which have become thickened with fat
deposits. Aspirin reduces the stickiness of platelets, and this helps prevent the platelets from sticking to the inside
of an artery and forming a thrombus. This reduces the risk of you having a heart attack or stroke. When aspirin is
used in this way, it is often referred to as 'low-dose' aspirin. Each tablet contains 75 mg of aspirin. Low-dose
aspirin can be recommended for people with heart or blood vessel disease, and for people who have had heart
bypass surgery. Most people who have recently had a heart attack or stroke will also be advised to take daily low-
dose aspirin to help to prevent it from happening again.

Low-dose aspirin tablets are available on prescription, and you can also buy them without a prescription.
However, do not take regular low-dose aspirin without discussing the advantages and disadvantages of doing so
with your doctor.

At higher doses, aspirin is used to relieve pain and high temperature (fever). There is more information about this
use of aspirin in a leaflet called Aspirin for pain or fever.

Before taking low-dose aspirin

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used
if extra care is taken. For these reasons, before you start taking aspirin it is important that your doctor or
pharmacist knows:

If you are pregnant or breast-feeding.

If you have ever had a stomach ulcer.
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If you have asthma.
If you are under 16 years of age.
If you have any problems with the way your liver works or with the way your kidneys work.
If you have a blood disorder such as haemophilia, or glucose-6-phosphate dehydrogenase (G6PD)
deficiency.
If you have ever had an unusual or allergic-type reaction after taking aspirin or a non-steroidal anti-
inflammatory drug (NSAID). NSAIDs include ibuprofen, diclofenac, indometacin and naproxen. You
should also let your doctor know if you have ever had an allergic reaction to any other medicine.
If you are taking any other medicines. This includes any medicines you are taking which are available
to buy without a prescription, such as herbal and complementary medicines.

How to take low-dose aspirin

Before you start taking aspirin, read the manufacturer's printed information leaflet from inside the pack.
It will give you more information about low-dose aspirin and will provide you with a full list of the side-
effects which you may experience from taking it.
It is likely you will be advised to take one (75 mg) tablet of aspirin each day. Your dose may be different
to this if, for example, you have recently had heart bypass surgery. Take the tablets exactly as your
doctor tells you to.
You can take aspirin at whatever time of day you find easiest to remember, but try to take your doses
at the same time of day each day. Most people prefer to take it in the morning with breakfast, as they
find this helps them to remember to take it.
Take a look at the label on the packet to find out what type of aspirin tablet you have been supplied
with. If you have been given dispersible aspirin tablets, take your dose stirred into a small amount of
water. It is important that you take this type of aspirin tablet with something to eat. This helps to reduce
the risk of any irritation to your stomach. Gastro-resistant aspirin tablets (also called enteric-coated,
or EC) do not have to be taken with food, as these tablets have a special coating which helps to
protect your stomach from irritation. These tablets must be swallowed whole without chewing, unless
your doctor has told you otherwise. You can take them with a drink of water to help you swallow.
If you are taking gastro-resistant aspirin tablets, do not take indigestion remedies during the two hours
before you take the aspirin or during the two hours after you have taken aspirin. This is because the
antacid in the indigestion remedy affects the way the coating on this type of tablet works.
If you forget to take a dose, take it as soon as you remember. If you do not remember until the
following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.

Getting the most from your treatment

Try to keep all your regular appointments with your doctor. This is so your doctor can check on your
progress.
Before buying or taking any 'over-the-counter' medicines, check with your pharmacist if the medicine
is safe for you to take. You should not take any other medicines which contain aspirin, and you should
also avoid buying any anti-inflammatory painkiller such as ibuprofen. Many cold and flu remedies
contain aspirin or ibuprofen.
Aspirin should not be given to a child under the age of 16 unless it has been prescribed by a doctor to
treat a specific condition. This is because it is possible that aspirin given to young children is
associated with a condition known as Reye's syndrome. Reye's syndrome is a very rare disease that
can be fatal.
If you are due to have an operation or dental treatment, tell the person carrying out the treatment that
you are taking aspirin. This is because any bleeding may take longer than normal to stop.
If you ever suspect that a child might have taken aspirin accidentally, go to the accident and
emergency department of your local hospital straightaway. This is very important because aspirin can
cause serious problems when it is taken accidentally or in overdose. Take the container with you to
show what has been taken, even if the pack is now empty.

Can low-dose aspirin cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone
experiences them. The table below contains some of the most common ones associated with aspirin. You will
find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often
improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the
following continue or become troublesome.
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Common aspirin
side-effects What can I do if I experience this?
Feeling sick, Stick to simple foods, and if you are not doing so, take your dose of aspirin after a meal. If this continues,
indigestion speak with your doctor for further advice
Increased risk of If you notice any unexplained bleeding, speak with a doctor for advice
bleeding

Important: aspirin may cause allergic reactions; this is more common in people who have asthma. Stop taking
aspirin and speak with a doctor urgently if you have an allergic reaction or develop any breathing difficulties.

If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or
pharmacist for further advice.

How to store aspirin

Keep all medicines out of the reach and sight of children.
Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this
medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is
empty.

This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.

Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

If you have any questions about this medicine ask your pharmacist.

Further reading & references

British National Formulary; 68th Edition (Sep 2014) British Medical Association and Royal Pharmaceutical Society of Great
Britain, London

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical
conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its
accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions.
For details see our conditions.

Original Author: Current Version: Peer Reviewer:

Helen Allen Helen Allen Dr Adrian Bonsall
Document ID: Last Checked: Next Review:
3206 (v25) 24/02/2015 23/02/2018

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