Genes Homo sapiens Sus scrofa

mRNA accession no. mRNA accession no.

(NCBI) (NCBI)
TBXA2R NM_001060.5(thromboxane A2
(thromboxane A2 receptor isoform alpha)
receptor) NM_201636.2(thromboxane A2
receptor isoform beta)
EDNRA(endothelin NM_001166055.1(endothelin-1 NM_214229.1 ( endothelin-1
receptor type A) receptor isoform b precursor) receptor precursor)
NM_001256283.1(endothelin-1
receptor isoform c)
NM_001957.3(endothelin-1
receptor isoform a precursor)
EDNRB(endothelin NM_000115.4( endothelin B NM_001038002.1( endothelin
receptor type B) receptor isoform 1 precursor) B receptor precursor
NM_001122659.2(endothelin B
receptor isoform 1 precursor)
NM_001201397.1( endothelin
B receptor isoform 3)
NM_003991.3(endothelin B
receptor isoform 2 precursor)
ADRA1A (alpha-1A NM_000680.3(alpha-1A NM_001123072.1( alpha-1A
adrenergic receptor ) adrenergic receptor isoform 1) adrenergic receptor)
NM_001322502.1(alpha-1A
adrenergic receptor isoform 5)
NM_001322503.1( alpha-1A
adrenergic receptor isoform 6)
NM_001322504.1(alpha-1A
adrenergic receptor isoform 7)
NM_033302.3(alpha-1A
adrenergic receptor isoform 3)
NM_033303.4(alpha-1A
adrenergic receptor isoform 2)
NM_033304.3(alpha-1A
adrenergic receptor isoform 4)
ADRA1D (alpha-1D NM_000678.3(alpha-1D NM_001123073.1(alpha-1D
adrenergic receptor ) adrenergic receptor) adrenergic receptor)
ADRB2(beta-2 NM_000024.5(beta-2 NM_001128436.1(beta-2
adrenergic receptor) adrenergic receptor) adrenergic receptor)
AGTR1 (angiotensin NM_000685.4( type-1 XM_003132469.3 ( type-1
II receptor type 1) angiotensin II receptor angiotensin II receptor)
isoform 1)
NM_004835.4 (type-1
angiotensin II receptor
isoform 2
NM_009585.3(type-1
 angiotensin II receptor isoform
1)
NM_031850.3 (type-1
angiotensin II receptor isoform
2)
NM_032049.3 (type-1
angiotensin II receptor isoform
3)

GNAQ (G protein NM_002072.4 (guanine NM_001038623.1 (guanine

subunit alpha q) nucleotide-binding protein G(q) nucleotide-binding protein
subunit alpha) G(q) subunit alpha)
PLCB1 NM_015192.3 (1- XM_013985062.1( 1-
(phospholipase C phosphatidylinositol 4,5- phosphatidylinositol 4,5-
beta 1) bisphosphate bisphosphate
phosphodiesterase beta-1 phosphodiesterase beta-1)
isoform a)
NM_182734.2 (1-
phosphatidylinositol 4,5-
bisphosphate
phosphodiesterase beta-1
isoform b)

PLCB2 NM_001284297.1 ( 1- XM_013985622.1 (1-

(phospholipase C phosphatidylinositol 4,5- phosphatidylinositol 4,5-
beta 2) bisphosphate bisphosphate
phosphodiesterase beta-2 phosphodiesterase beta-2)
isoform 2)
NM_001284298.1( 1-
phosphatidylinositol 4,5-
bisphosphate
phosphodiesterase beta-2
isoform 3)
NM_001284299.1 (1-
phosphatidylinositol 4,5-
bisphosphate
phosphodiesterase beta-2
isoform 4)
NM_004573.2 (1-
phosphatidylinositol 4,5-
bisphosphate
phosphodiesterase beta-2
isoform 1)
PLCB3 NM_000932.2 (1- XM_003353792.4 ( 1-
(phospholipase C phosphatidylinositol 4,5- phosphatidylinositol 4,5-
beta 3) bisphosphate bisphosphate
phosphodiesterase beta-3 phosphodiesterase beta-3)
isoform 1)
 NM_001184883.1 (1-
phosphatidylinositol 4,5-
bisphosphate
phosphodiesterase beta-3
isoform 2)
NM_001316314.1 ( 1-
phosphatidylinositol 4,5-
bisphosphate
phosphodiesterase beta-3
isoform 1)

GNAI1 (G protein NM_001256414.1 ( guanine NM_001123115.1 (guanine

subunit alpha i 1) nucleotide-binding protein G(i) nucleotide-binding protein
subunit alpha-1 isoform 2) G(i) subunit alpha-1)
NM_002069.5 ( guanine
nucleotide-binding protein G(i)
subunit alpha-1 isoform 1)

GNAI2 (G protein NM_001166425.1 (guanine NM_001123116.1 (guanine

subunit alpha i 2) nucleotide-binding protein G(i) nucleotide-binding protein
subunit alpha-2 isoform 2) G(i) subunit alpha-2)
NM_001282617.1 ( guanine
nucleotide-binding protein G(i)
subunit alpha-2 isoform 3)
NM_001282618.1 (guanine
nucleotide-binding protein G(i)
subunit alpha-2 isoform 4)
NM_001282619.1 (guanine
nucleotide-binding protein G(i)
subunit alpha-2 isoform 5)
NM_001282620.1 ( guanine
nucleotide-binding protein G(i)
subunit alpha-2 isoform 6)
NM_002070.3 (guanine
nucleotide-binding protein G(i)
subunit alpha-2 isoform 1)
GNAI3 (G protein NM_006496.3 (guanine NM_001123117.1 (guanine
subunit alpha i 3) nucleotide-binding protein G(k) nucleotide-binding protein
subunit alpha ) G(k) subunit alpha)
Relaxant Pathways

PTGIR(prostaglandin NM_000960.3 (prostacyclin XM_003355952.3

I2 (prostacyclin) receptor) ( prostacyclin receptor)
receptor (IP))
GNAS (G protein NM_000516.5 (protein GNAS NM_001130215.2 (SCG6
subunit alpha s isoform GNASL) (secretogranin VI) isoform
complex locus) NM_001077488.3 (protein SCG6)
 GNAS isoform f) NM_001171983.2 (guanine
NM_001077489.3 ( protein nucleotide-binding protein
GNAS isoform g) G(s) subunit alpha isoform
NM_001077490.2 (protein GNASS)
ALEX isoform Alex) NM_001171984.2 (guanine
NM_001309840.1 ( protein nucleotide-binding protein
ALEX isoform h) G(s) subunit alpha isoform f)
NM_001309842.1 ( protein NM_001171985.2 (guanine
ALEX isoform i) nucleotide-binding protein
NM_001309861.1 G(s) subunit alpha isoform g)
(NP_001296790.1 protein ALEX NM_214312.3 ( guanine
isoform h) nucleotide-binding protein
NM_001309883.1 ( protein G(s) subunit alpha isoform
ALEX isoform Alex) GNASL)
NM_016592.3 (protein SCG6
(secretogranin VI) isoform
SCG6)
NM_080425.3 (protein GNAS
isoform XLas)
NM_080426.3 (protein GNAS
isoform GNASS)
ADCY1 (adenylyl NM_001281768.1 (adenylate XM_013985803.1 (adenylate
cyclase isoform 1) cyclase type 1 isoform 2) cyclase type 1)
NM_021116.2 (adenylate
cyclase type 1 isoform 1)
ADCY2 (adenylyl NM_020546.2 (adenylate XM_013984935.1 (adenylate
cyclase isoform 2) cyclase type 2) cyclase type 2)
ADCY3 (adenylyl NM_001320613.1 ( adenylate XM_013996299.1 (adenylate
cyclase isoform 3) cyclase type 3 isoform 1) cyclase type 3)
NM_004036.4 (adenylate
cyclase type 3 isoform 2)

ADCY4 (adenylyl NM_001198568.1 (adenylate XM_001927556.6 (adenylate

cyclase isoform 4) cyclase type 4) cyclase type 4 isoform X5)
NM_001198592.1 (adenylate XM_013978178.1 (adenylate
cyclase type 4) cyclase type 4 isoform X2)
NM_139247.3 (adenylate XM_013978180.1 (adenylate
cyclase type 4) cyclase type 4 isoform X4)
XM_013978179.1 (adenylate
cyclase type 4 isoform X3)
XM_013978176.1 (adenylate
cyclase type 4 isoform X1)
ADCY5 (adenylyl NM_001199642.1 ( adenylate XM_013982377.1 (LOW
cyclase isoform 5) cyclase type 5 isoform 2) QUALITY PROTEIN: adenylate
NM_183357.2 (adenylate cyclase type 5)
cyclase type 5 isoform 1)

ADCY6 (adenylyl NM_015270.4 (adenylate XM_005655538.2 (adenylate

cyclase isoform 6) cyclase type 6)
ADCY7 (adenylyl NM_001114.4 (adenylate
cyclase isoform 7) cyclase type 7 isoform 1)
NM_001286057.1 (adenylate
cyclase type 7 isoform 2)
ADCY8 (adenylyl NM_001115.2 (adenylate
cyclase isoform 8) cyclase type 8)
ADCY9 (adenylyl NM_001116.3 (adenylate
cyclase isoform 9) cyclase type 9)
NOS3 (Nitric Oxide NM_000603.4 (nitric oxide
Synthase 3) synthase, endothelial isoform
1)
NM_001160109.1 (nitric oxide
synthase, endothelial isoform
2)
NM_001160110.1 (nitric oxide
synthase, endothelial isoform
3)
NM_001160111.1 (nitric oxide
synthase, endothelial isoform
4)
cyclase type 6 isoform X2)
XM_003481563.3 (adenylate
cyclase type 6 isoform X1)
XM_013991544.1 (adenylate
cyclase type 7)
XM_013996473.1 (adenylate
cyclase type 8)
XM_013992674.1 (adenylate
cyclase type 9 isoform X1)
XM_013992681.1 (adenylate
cyclase type 9 isoform X3)
XM_013992678.1 (adenylate
cyclase type 9 isoform X2)
XM_013992685.1 ( adenylate
cyclase type 9 isoform X4)
XM_013992691.1 (adenylate
cyclase type 9 isoform X5)
NM_214295.1 (nitric oxide
synthase, endothelial)

GUCY1B3 (soluble NM_000857.3 (guanylate NM_001018032.1 (guanylate

Guanylate Cyclase cyclase soluble subunit beta-1 cyclase soluble subunit beta-
beta subunit) isoform 2) 1)
NM_001291951.1 ( guanylate
cyclase soluble subunit beta-1
isoform 1)
NM_001291952.1( guanylate
cyclase soluble subunit beta-1
isoform 3)
NM_001291953.1 (guanylate
cyclase soluble subunit beta-1
isoform 4)
NM_001291954.1(guanylate
cyclase soluble subunit beta-1
isoform 5)
NM_001291955.1(guanylate
 cyclase soluble subunit beta-1
isoform 6)
GUCY1A3 (soluble NM_000856.5 (guanylate NM_001018033.1 (guanylate
Guanylate Cyclase 1 cyclase soluble subunit alpha-3 cyclase soluble subunit alpha-
alpha subunit) isoform A) 3)
NM_001130682.2 (guanylate
cyclase soluble subunit alpha-3
isoform A)
NM_001130683.3 (guanylate
cyclase soluble subunit alpha-3
isoform A)
NM_001130684.2 (guanylate
cyclase soluble subunit alpha-3
isoform A)
NM_001130685.2 (guanylate
cyclase soluble subunit alpha-3
isoform B)
NM_001130687.2 (guanylate
cyclase soluble subunit alpha-3
isoform D)
NM_001256449.1 (guanylate
cyclase soluble subunit alpha-3
isoform A)

PRKACA (protein NM_001304349.1 (cAMP- XM_003123353.3(cAMP-

kinase cAMP- dependent protein kinase dependent protein kinase
activated catalytic catalytic subunit alpha isoform catalytic subunit alpha isoform
subunit alpha) 3) X1)
NM_002730.3(cAMP-
dependent protein kinase XM_003354103.3(cAMP-
catalytic subunit alpha isoform dependent protein kinase
Calpha1) catalytic subunit alpha
NM_207518.2(cAMP- isoform X2)
dependent protein kinase
catalytic subunit alpha isoform
Calpha2)
RAPGEF3(Rap NM_001098531.2(rap guanine XM_005658312.2 (rap
guanine nucleotide nucleotide exchange factor 3 guanine nucleotide exchange
exchange factor 3 isoform a) factor 3)
(EPAC1)) NM_001098532.2( rap guanine
nucleotide exchange factor 3
isoform b)
NM_006105.5 (rap guanine
nucleotide exchange factor 3
isoform b)

RAPGEF4(Rap NM_001100397.1( rap guanine XM_013990580.1(rap guanine

 guanine nucleotide nucleotide exchange factor 4
exchange factor 4 isoform b)
(EPAC2)) NM_001282899.1(rap guanine
nucleotide exchange factor 4
isoform c)
NM_001282900.1(rap guanine
nucleotide exchange factor 4
isoform d)
NM_001282901.1(rap guanine
nucleotide exchange factor 4
isoform e)
NM_007023.3( rap guanine
nucleotide exchange factor 4
isoform a)
nucleotide exchange factor 4
isoform X3)
XM_003133488.5(rap guanine
nucleotide exchange factor 4
isoform X1)
XM_013990579.1( rap
guanine nucleotide exchange
factor 4 isoform X2)
XM_013990582.1(rap guanine
nucleotide exchange factor 4
isoform X5)
XM_013990581.1( rap
guanine nucleotide exchange
factor 4 isoform X4)

XM_005657542.2 ( rap
guanine nucleotide
exchange factor 4 isoform
X6)
Other Hypoxia-Sensitive Genes

CAT (catalase) NM_001752.3(catalase) NM_214301.2(catalase)

SOD1 (superoxide NM_000454.4(superoxide NM_001190422.1(superoxide
dismutase 1) dismutase [Cu-Zn]) dismutase [Cu-Zn])
SOD2 (superoxide NM_000636.3(superoxide NM_214127.2(superoxide
dismutase 2) dismutase [Mn], mitochondrial dismutase [Mn],
isoform A precursor) mitochondrial)
NM_001024465.2(superoxide
dismutase [Mn], mitochondrial
isoform A precursor)
NM_001024466.2( superoxide
dismutase [Mn], mitochondrial
isoform B)
NM_001322814.1( superoxide
dismutase [Mn], mitochondrial
isoform B)
NM_001322815.1(superoxide
dismutase [Mn], mitochondrial
isoform C precursor)
NM_001322816.1(superoxide
dismutase [Mn], mitochondrial
isoform D)
NM_001322817.1(superoxide
dismutase [Mn], mitochondrial
isoform E)
NM_001322819.1(superoxide
dismutase [Mn], mitochondrial
 isoform E)
NM_001322820.1( superoxide
dismutase [Mn], mitochondrial
isoform E)
HIF1A (hypoxia NM_001243084.1( hypoxia- NM_001123124.1(hypoxia-
inducible factor 1 inducible factor 1-alpha isoform inducible factor 1-alpha)
alpha subunit) 3)
NM_001530.3(hypoxia-
inducible factor 1-alpha isoform
1)
NM_181054.2( hypoxia-
inducible factor 1-alpha isoform
2)
VEGFA(vascular NM_001025366.2( vascular NM_214084.1( vascular
endothelial growth endothelial growth factor A endothelial growth factor A
factor A) isoform a) precursor)
NM_001025367.2(vascular
endothelial growth factor A
isoform c)
NM_001025368.2(vascular
endothelial growth factor A
isoform d)
NM_001025369.2(vascular
endothelial growth factor A
isoform e)
NM_001025370.2(vascular
endothelial growth factor A
isoform f)
NM_001033756.2(vascular
endothelial growth factor A
isoform g)
NM_001171622.1(vascular
endothelial growth factor A
isoform h)
NM_001171623.1(vascular
endothelial growth factor A
isoform i precursor)
NM_001171624.1( vascular
endothelial growth factor A
isoform j precursor)
NM_001171625.1(vascular
endothelial growth factor A
isoform k precursor)
NM_001171626.1(vascular
endothelial growth factor A
isoform l precursor)
 NM_001171627.1(vascular
endothelial growth factor A
isoform m precursor)

NM_001171628.1(vascular
endothelial growth factor A
isoform n precursor)
NM_001171629.1(vascular
endothelial growth factor A
isoform o precursor)
NM_001171630.1(vascular
endothelial growth factor A
isoform p precursor)
NM_001204384.1(vascular
endothelial growth factor A
isoform q precursor)
NM_001204385.1(vascular
endothelial growth factor A
isoform r)
NM_001287044.1(vascular
endothelial growth factor A
isoform s)
NM_001317010.1(vascular
endothelial growth factor A
isoform VEGF-Ax precursor)
NM_003376.5(NP_003367.4
vascular endothelial growth
factor A isoform b)
CALM1(calmodulin NM_006888.4(calmodulin) NM_001244210.1(calmodulin)
1)
Selected Mito Proteins

SDHA(succinate NM_001294332.1(succinate XM_013992340.1(LOW

dehydrogenase dehydrogenase [ubiquinone] QUALITY PROTEIN: succinate
complex flavoprotein flavoprotein subunit, dehydrogenase [ubiquinone]
subunit A (Complex mitochondrial isoform 2) flavoprotein subunit,
II)) NM_001330758.1(succinate mitochondrial)
dehydrogenase [ubiquinone]
flavoprotein subunit,
mitochondrial isoform 3)
NM_004168.3(succinate
dehydrogenase [ubiquinone]
flavoprotein subunit,
mitochondrial isoform 1)

SDHB (succinate NM_003000.2(succinate NM_001104953.1(succinate

dehydrogenase dehydrogenase [ubiquinone] dehydrogenase [ubiquinone]
complex iron sulfur iron-sulfur subunit, iron-sulfur subunit,
subunit B (Complex mitochondrial precursor) mitochondrial precursor)
II))
SDHC(succinate NM_001035511.1(succinate XM_003125659.5(succinate
dehydrogenase dehydrogenase cytochrome dehydrogenase cytochrome
complex subunit C b560 subunit, mitochondrial b560 subunit, mitochondrial)
(Complex II)) isoform 2 precursor)
NM_001035512.1(succinate
dehydrogenase cytochrome
b560 subunit, mitochondrial
isoform 3 precursor)
NM_001035513.1(succinate
dehydrogenase cytochrome
b560 subunit, mitochondrial
isoform 4 precursor)
NM_001278172.1(succinate
dehydrogenase cytochrome
b560 subunit, mitochondrial
isoform 5 precursor)
NM_003001.3(succinate
dehydrogenase cytochrome
b560 subunit, mitochondrial
isoform 1 precursor)
UQCRFS1(ubiquinol- NM_006003.2 (cytochrome b- ------
cytochrome c c1 complex subunit Rieske,
reductase, Rieske mitochondrial)
iron-sulfur
polypeptide 1
(Complex III))
CYC1 (cytochrome c1 NM_001916.4(cytochrome c1, -----
(Complex III)) heme protein, mitochondrial
precursor)
ATP5I (ATP synthase, NM_007100.3 (ATP synthase NM_213915.1 (ATP synthase
H+ transporting, subunit e, mitochondrial) subunit e, mitochondrial)
mitochondrial Fo
complex subunit E
(Complex V))
PDK1 (pyruvate NM_001278549.1 ([Pyruvate NM_001159608.1([Pyruvate
dehydrogenase dehydrogenase (acetyl- dehydrogenase (acetyl-
kinase 1) transferring)] kinase isozyme 1, transferring)] kinase isozyme
mitochondrial isoform 1 1, mitochondrial)
precursor)
NM_002610.4 ([Pyruvate
dehydrogenase (acetyl-
transferring)] kinase isozyme 1,
mitochondrial isoform 2
precursor)