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Human Fat Tissue: A Microwave Communication

Channel
Noor Badariah Asan, Syaiful Redzwan, Anders Daniel Noreland1, Emadeldeen Hassan1,2
Rydberg, Robin Augustine 1- Department of Computing Sciences, Ume University,
Microwave Group, Solid State Electronics Division, Ume, SE-901 87, Sweden.
Department of Engineering Sciences, Uppsala University, 2- Department of Electronics and Electrical
Uppsala, Sweden. Communications, Menoufia University, 32952- Menouf,
Egypt.

Thiemo Voigt
Department of Information Technology,
Division of Computer Systems, Uppsala University,
Uppsala, Sweden.

AbstractIn this paper, we present an approach for There are many factors that affect the dielectric properties
communication through human body tissue in the R-band of materials such as frequency, temperature, and humidity.
frequency range. This study examines the ranges of microwave Materials in biological tissues, specifically, are divided into
frequencies suitable for intra-body communication. The human two main categories, which are with high and low water
body tissues are characterized with respect to their transmission contents. Muscle and skin have high water content with (73-78
properties using simulation modeling and phantom %) and (60-76 %), respectively, while fat and bone have low
measurements. The variations in signal coupling with respect to water content which is (5-10 %), and (8-16 %), respectively
different tissue thicknesses are studied. The simulation and [10]. This is consistent with the fact that fat tissues are
phantom measurement results show that electromagnetic
hydrophobic and have low dielectric loss compared to other
communication in the fat layer is viable with attenuation of
tissue layers. It is a condition, necessary for using a tissue to be
approximately 2 dB per 20 mm.
used as a communication medium with minimal losses and
Keywords tissue characterization; transmission medium; high degree of information privacy. This paper investigates two
biomedical sensor; channel model; phantom measurement. different three-layer models of human tissues. We study the
signal coupling and the biological properties as the signal
propagates through the tissues.
I. INTRODUCTION
Recently, many implanted sensors are used to monitor The remaining paper is structured as follows. After a short
critical internal body factors. These require direct introduction on communication in human body, we discuss the
communication between implants through the body tissues. simulation and measurement setup in Section II. Furthermore,
The human body has been characterized to act as a the effects of varying the thickness and the length are explored
communication channel by comparing the amplitude, carrier in Section III. The paper is wrapped up with concluding
frequency, modulation method, and the data rate between the remarks in Section IV.
signal coupling [1]. Several attempts have been made in tissue
characterization for communication based on capacitive [2,3] II. SIMULATION AND MEASUREMENT SETUP
and galvanic coupling [4-6]. The characterization of the human
body as a communication channel at low frequencies (10k Hz A. Simulation Modeling
to 1 MHz) is shown in [7]. In 2007, clinical trials had been Simulations have been processed using the transient solver
done to characterize the human tissues for intra-body of the Computer Simulation Technology - CST Microwave
communication using galvanic coupling [8]. To the best of our Studio package. Simulations were done with three layers
knowledge, none of the presented works has characterized homogeneous tissues; skin, fat, and muscle. In order to
different human tissue layers to find out the best medium suited suppress the effects of the thickness variation, we designed two
for intra-body microwave communication. Implantable devices models, separately. In the first model, we tried to vary the
usually do not rely on external sources and can include thickness of the fat and the muscle layers to see their effect on
networks of sensors. Thus, low power consumption and high signal coupling. With notation according to Fig. 1, the first
data rate are the main requirements for medical implant devices model has a dimension of 75 mm (W) x 75 mm (L), whereas
[9]. The R-band is chosen as a compromise between the low the thickness of the fat (tF) and the muscle (tM) are varied to
losses and high bandwidth. study the behavior. The studies are based on the evaluation of
the scattering parameters (the S-parameters).

978-1-5386-1713-7/17/$31.00 2017 IEEE


B. Measurement Setup
The representative phantoms of human skin, fat, and
muscle are fabricated. For skin and muscle phantom, we used
agar-based compound and for representing fat, adhesive putty
was used since it has the physical consistency and dielectric
properties of human fat. For realizing the probe, a topology
optimized monopole antenna was fabricated on a substrate
(RO3203) with properties similar to that of human fat. The
probe cavity is filled with rubber which can be easily machined
and has the same dielectric properties as fat. Fig. 3 shows the
Fig. 1. First model of three layer tissues dimensions
antenna (left), and the probe (right). The monopole antenna is
positioned at the center of the probe. Table II shows the
In the second model, Fig. 2, to replace the CST waveguide dielectric properties of the tissue-equivalent phantom at 2 GHz.
ports, we used more realistic probe models. The probe consists
of a SMA connector, optimized antenna, and a dielectric filled
rectangular waveguide. The dielectric of the rectangular
waveguide has properties similar to that of human fat to ensure
electromagnetic continuity. In Fig. 2, W = 50.52 mm, the
thickness of the skin, fat, and muscle are tS = 2 mm, tF = 25
mm, and tM = 30 mm, respectively, and the length (L) is varied
from 20 mm to 60 mm. The thickness of the muscle was
chosen based on the studies in the first model, while the Fig. 3. Topology optimized monopole antenna [12] and the waveguide
thickness of the fat was taken considering the average thickness
of the fat layer in human body [11]. The probe, which consists
of a coax to waveguide transition, is smaller than the standard TABLE II. DIELECTRIC PROPERTIES OF THE TISSUE-EQUIVALENT
WR-430 waveguide. A topology optimized monopole antenna PHANTOM AT 2 GHZ
[12] is used as a radiating source. Table I shows the dielectric
Tissues Relative Permittivity, r Conductivity, (S/m)
properties of the human body tissues at 2 GHz. The antenna is
optimized to ensure that it is operating at the R-band (1.7 to 2.6 Skin 38.92 8.15
GHz) which partly overlaps the Industrial, Scientific and
Rubber Adhesive putty Rubber Adhesive putty
Medical (ISM) band. Fat
4.7 4.87 0.01 0.10

Muscle 49.35 10.17

Fig. 4 shows the experimental setup for the three layers


equivalent phantom. The probe is placed at either ends of the
phantom, aligned with the fat layer. The signal propagates
through the fat phantom layer from probe 1 and is received at
probe 2. The S11 and S21 parameters are obtained using the
Fieldfox Microwave Analyzer (N9918A).

Fig. 2. Second model of three layer tissues dimensions

TABLE I. DIELECTRIC PROPERTIES OF THE HUMAN BODY TISSUES AT 2


GHZ [13]

Tissues Relative Permittivity, r Conductivity, (S/m)


Skin 38.57 1.27

Fat 5.33 0.09

Muscle 53.29 1.45


Fig. 4. Image of the overall measurement setup
III. RESULTS AND DISCUSSION increase of the thickness of the fat layer. It can be seen that, the
In this section, we discuss the simulation and measurement amplitude of the coupling coefficient S21 at 10 mm is -28 dB
results. while it increases to around -15 dB at 30 mm thickness.
Therefore, it could be possible to use the fat layer as a
communication channel in human body. For the simulation
A. Probe Optimization results shown in Fig. 8, we vary the muscle tissue from 20 mm
The probe is optimized for the frequency band of operation. to 60 mm whereas the thickness of the fat layer was fixed at 25
Fig. 5 (a) shows a cross-section of the probe-to-probe coupling mm. Fig.8 shows that the variations in the thickness of the
model in CST, and Fig. 5 (b) shows the probe-to-probe muscle layer have a minor impact on the signal transmission
configuration during the measurement. The measurement through the fat layer (the amplitude of S11 and S21 do not
results correlate with the simulation results as shown in Fig. 6. change much by varying the muscle thickness).
We can see that the probe is operating at 2 GHz during the 0
measurement, and it corresponds well with the simulation
-5
results which is at 2.02 GHz. Therefore, for the analysis of the
results, we concentrate on the transmission through the fat -10

tissues at the probe operating frequency 2 GHz. -15

Magnitude (dB)
-20

-25

-30
S11 - Fat = 10 mm
S11 - Fat = 20 mm
-35 S11 - Fat = 30 mm
S21 - Fat = 10 mm
-40 S21 - Fat = 20 mm
S21 - Fat = 30 mm
-45
1.7 1.8 1.9 2 2.1 2.2 2.3 2.4 2.5 2.6
Frequency (GHz)

Fig. 7. The effect of the fat tissue thicknesses on S11 and S21
(a)
0

-5

-10

-15
Magnitude (dB)

-20

-25

-30 S11 - Muscle = 20 mm


S11 - Muscle = 30 mm
-35 S11 - Muscle = 40 mm
(b) S21 - Muscle = 20 mm
-40 S21 - Muscle = 30 mm
Fig. 5. The probe-to-probe model (a) CST simulation; (b) measurement S21 - Muscle = 40 mm
-45
0 1.7 1.8 1.9 2 2.1 2.2 2.3 2.4 2.5 2.6
Frequency (GHz)

-5 Fig. 8. The effect of the muscle tissues thicknesses on S11 and S21

-10
Magnitude (dB)

C. Comparison with respect to the tissue length


-15
An experimental setup is prepared and measurements have
been conducted to validate the simulation results. Fig. 9 and
-20
Fig. 10 show the comparison between the simulation and the
S11 - Measurement
S21 - Measurement measurement results for both S11 and S21. As shown in Fig. 9,
-25 S11 - CST Software Simulation
S21 - CST Software Simulation the trend of frequency shift with respect to tissue length is
-30
comparable for both the simulation and the measurement. The
1.7 1.8 1.9 2 2.1 2.2
Frequency (GHz)
2.3 2.4 2.5 2.6
absolute difference between the simulation and measurement
values is expected because of the discrepancy in the simulation
Fig. 6. The simulation and the measurement results (probe-to-probe) model compared to the measurement setup. The fat phantom is
made of adhesive putty to represent the physical consistency of
B. The effect of tissues thickness on signal coupling human fat and therefore, it lacks the cuboid shape used in
simulation, which is primarily the reason for the variations in
In CST simulation, we vary the thickness of the fat and the result. In addition, the discrepancy can also be due to the air
muscle tissues to analyze the effect on signal transmission bubbles trapped inside the adhesive putty itself, and also in
through each tissue. We vary the thickness of fat tissue from 10 between the probes contact area.
mm to 30 mm. As shown in Fig. 7, the amplitude of the
transmission coefficient S21 increases with respect to the
The results analysis is more focused on the S21 results polarization effects in both homogeneous and heterogeneous
rather than the S11 results. In Fig. 10, from both the human tissue models will be pursued in the future work.
measurement and simulation, it can be deduced that the
coupling drops around 2 dB when the length is varied from 20 ACKNOWLEDGMENT
mm to 40 mm, and from 40 mm to 60 mm, respectively.
This work was supported by Ministry of Higher Education,
0
Malaysia, Universiti Teknikal Malaysia Melaka (UTeM),
-5 Eurostars project (grant E-9655-COMFORT), Swedish
Vinnova project (grant BDAS) and a strategic collaborative
-10
eScience program by Swedish Research Council (grant
Magnitude (dB)

-15
eSSENCE) for funding this research.

-20
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