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1st ANC
bimanual palpation
normal size
top normal size 7 week size ( )
GA > 12 week (Fundal height above PS)
PS umbilicus 3 FH
1/3 > PS GA 12-14 week
2/3 > PS GA 14-16 week
At Umbilicus GA 20 week (average 20-22 week)
umbilicus
upper border of PS Fundus
(
)
? Heart
and lung?
> Baseline Lab (Lab I)
investigation
Lab 1
CBC c platelet , Blood group ABO, Rh ? MCV
VDRL, Anti-HIV, HBsAg STD
UA WBC, Sugar, Albumin
Thalassemia screening
3
Beta thalassemia major (Bo/Bo)
Barts hydrops fetalis (/)
Beta thalassemia E disease (Be/Bo)
MCV 80 fL
MCV < 80 fL DDx IDA, Thalassemia, ACD
MCV < 80 fL Beta thal-trait, E-trait, Alpha-thal trait
MCV > 80 fL E-trait
MCV screen Beta, Alpha
DCIP screen HbE ( HbE screening)
2 MCV/DCIP
neg/neg (no risk)
positive risk
high risk
worst case screnario
> any neg/neg no risk
> any pos/pos at risk
> any pos/neg at risk
> neg/pos at risk neg/pos no risk
at risk HbTyping, PCR for alpha thal
DM screening :
risk for GDM Low/Intermediate High risk
High risk Glucose challenge test (GCT) 1st ANC
intermediate risk GA 24-28 week
high risk for GDM
> Maternal obesity BMI > 30 kg/m2
> History of previous GDM
> History of 1st degree relative with DM
> Persistent glycosuria (UA dipstick 2+ x 1 , 1+ x 2 )
GCT stat
Option Down screening
Down screening
Downs syndrome marker U/S Nuchal translucency
GA11-14 week risk Prenatal diagnosis ?
Nutrition and Supplements
2,500 kcal
3
Iron
1,000 mg
anemia in pregnancy
trimester Hb cut off
1st trimester : Hb < 11 anemia
2nd trimester : Hb < 10.5 anemia
3rd trimester : Hb < 11 anemia
Hb anemia
6-7 mg/day
18-20 mg/day
10-20% 3 mg/day
3 mg/day elemental iron 30 mg
Ferrous fumarate 1x1 po pc
Ferrous fumarate 200 mg elemental iron 65 mg 10-20%
6-13 mg
30 mg/day : Ferrous fumarate 1x1 po pc
60-100 mg/day Ferrous fumarate 1x1 to 1x2 po pc
anemia iron deficiency cause
treatment elemental iron 200 mg/day
20-25 mg/day
treat IDA Ferrous fumarate 1x3 po pc
5-10 days : reticulocyte count
2-3 weeks : Hb 0.3-1.0 g/dl / week
Summary
Iron supplement : consider Hb/Hct
Hct < 30 mg% : Ferrous Fumarate 1x3
Hct 30-33 mg% : Ferrous Fumarate 1x2
Hct > 33 mg% : Ferrous Fumarate 1x1
Folic Supplement
Neural tube defect
Folic 0.4 mg/day
embryogenesis and early organogenesis Folic acid
Neural tube defect 4 mg/day 3
Folic acid 0.5-1 mg
4 mg/day Folic acid (5 mg) 1x1 po pc
Iodine
iodine
concern endemic area of hypothyroidism congenital hypothyroidism
cretinism
Recommended supplementation regimen
choice
Folic acid (5) 1x1 po pc
Ferrous fumarate morning sickness
S/E GI upset
morning sickness Vit B6 (Pyridoxine) (10) 1x3 po pc
morning sickness
Triferdine, Obimin AZ, Ferli-6 1x1 po pc