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3- A 48-year-old obese man presents to his primary care physician with complaints
of lower leg pain that occurs after he walks a few city blocks and is relieved with
rest. He has no other complaints. His blood pressure is 165/85 mmHg, his pulse is
83/min and his respiratory rate is 18/min. After further questioning, he admits to
smoking two packs of cigarettes per day. Which of the following types of vessels is
most likely involved in the pathological process surrounding this patients
symptoms?
(A) Arteries
(B) Arterioles
(C) Capillaries
(D) Veins
(E) Venules
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5- A 45-year-old man comes to his primary care physician complaining of back
pain. On questioning, the patient indicates a recent history of polyuria, polydipsia,
hypertension, and weight gain. X-ray of the spine shows an L4-L5 compression
fracture. Which of the following is most likely to be elevated in this patient?
(A) Cortisol
(B) Glucagon
(C) Growth hormone
(D) Insulin
(E) Thyroid hormone
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albumin level of 7.5g/dL. Which of the following conditions would most likely
cause this patients abnormalities?
(A) Acute infection
(B) Chronic liver disease
(C) Dehydration
(D) Nephrotic syndrome
(E) Poor nutritional status
12- A 56-year-old man is diagnosed with transitional cell carcinoma and treated
with excision and chemotherapy. Which of the following risk factors most likely
led to his cancer?
(A) Alcohol use
(B) Exposure to aniline dyes
(C) Exposure to asbestos
(D) Hypertension
(E) Previous pyelonephritis
13- A patient with relapsing Hodgkins disease presents with weight gain, foot
ulcers, vision problems, elevated blood sugar, oral candidiasis, and new onset
of wildly swinging mood changes. What is the most likely etiology of this
patients psychiatric symptoms?
(A) Adverse effects of bleomycin
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(B) Adverse effects of prednisone
(C) Adverse effects of vincristine
(D) Normal psychiatric response to having cancer
(E) Progression of disease
14- A 70-year-old man comes to his physician for a routine physical examination.
Although he is asymptomatic, a blood test shows an abnormal level of
immunoglobulin. After Further testing he is diagnosed with monoclonal
gammopathy of undetermined significance. Which of the following is the
current treatment of monoclonal gammopathy of undetermined significance?
(A) Alendronate
(B) Anticoagulation
(C) High-dose steroids
(D) No treatment
(E) Vinca alkaloids
15- An otherwise healthy infant boy born via vaginal delivery has an abnormal
appearance of his right upper limb. His arm hangs by his side, pronated and
medially rotated. Which of the following muscles is still functioning in this
patient?
(A) Biceps
(B) Deltoid
(C) Infraspinatus
(D) Supraspinatus
(E) Triceps
19- A 50-year-old slightly obese man comes to the emergency department with his
wife at 3 am complaining of severe pain in his left great toe. He said the pain
began 5 hours ago while he was walking home after dinner, which consisted of
steak and a few beers. His serum studies are unremarkable except for negative
blood cultures and an elevated uric acid level. When asked about allergies, the
patient states that he is allergic to nonsteroidal anti-inflammatory drugs. An
aspiration of the toe reveals negatively birefringent crystals. Which of the
following is the best acute treatment for this condition?
(A) Allopurinol
(B) Ceftriaxone
(C) Colchicine
(D) Hydrochlorothiazide
(E) Ibuprofen
(F) Indomethacin
(G)Naproxen
20- A 31-year-old man comes to the clinic complaining of red and itchy eyes for the
past 8 hours. The patient has had pain on urination and diffuse joint pain for 1
month, but tested negative gonorrhea and Chlamydia on a previous visit 3 weeks
ago. He has also tested for negative for rheumatoid factor, and his human
leukocyte antigen (HLA) status is HLA-B27. When asked about any recent
illnesses, all the patient can recall is going to the emergency department 2 months
ago for a bad case of diarrhea. Which of the following is the most likely diagnosis
(A) Lyme arthritis
(B) Psoriatic arthritis
(C) Reiters syndrome
(D) Rheumatoid arthritis
(E) Systemic lupus erythematosus
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21- A 1-year-old adopted darkly pigmented boy is brought to the pediatrician for
his first well-child check-up. The adoptive parents do not know any of the infants
past medical history or family history. Physical examination reveals an unusual
widening of the childs wrists and ankles and marked enlargement of the childs
costochondral junctions. What is a characteristic laboratory finding used to
support the most likely diagnosis
(A) Increased intact parathyroid hormone level
(B) Increased serum calcium level
(C) Increased serum 1,25-dihydroxycholecalciferol level
(D) Increased serum 25-hydroxycholecalciferon level
(E) Increased serum phosphorus level
23- A 60-year-old man presents to the physician with a limp that he has had since
childhood. When he walks, the patient takes a step with his right leg, and then
leans all the way over to his right so that he can swing his left leg to take a step. He
reports one major illness as a child, after which he developed this limp. Which of
the following nerve(s) is most likely injured in the patient?
(A) Inferior gluteal nerve
(B) L5 and S1
(C) Obturator nerve
(D) S1 and S2
(E) Superior gluteal nerve
26- A 27-year-old man comes to the physicians office with a 6-month history of low
back pain and stiffness that wakes him up during the night and is worst in the
morning. The patient was diagnosed with bilateral sacroiliatis 4 months ago
because of his tenderness to percussion of the sacroiliac joints and pain on
springing the pelvis up. He has severe limitation of motion of his lumbar spine.
Laboratory test results are negative for antinuclear antibody and rheumatoid
factor, and show the patients human leukocyte antigen status is B27 positive.
Which of the following is the most likely diagnosis?
(A) Ankylosing spondylitis
(B) Osteoarthritis
(C) Psoriatic arthritis
(D) Reiter,s syndrome
(E) Rheumatoid arthritis
(F) Vertebral compression fracture
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(D) Phalanges
(E) Scaphoid
28- During the autopsy of a patient who complained of a severe headache shortly
before dying , the pathologist removes the calvarium with the dura attached.
On the surface of the brain, there is a frank blood on visual inspection that she
is unable to remove by rubbing or scrapping the surface. Which of the
following types of hemorrhages most likely caused this finding?
(A) Epidural hemorrhage
(B) Intradural hemorrhage
(C) Parenchymal hemorrhage
(D) Subarachnoid hemorrhage
(E) Subdural hemorrhage
29- A 40-year-old man was admitted to the neurology service for the evaluation
of persistent numbness over his left jaw and lower face. MRI reveals a
schwannoma, which is compressing a cranial nerve as the nerve exits the skull.
The cranial nerve involved in this case exits the skull through which of the
following foramina?
(A) Foramen ovale
(B) Foramen rotundum
(C) Foramen spinosum
(D) Jugular foramen
(E) Superior orbital fissure
32- A 2-week-old girl is brought to the pediatrician for her first doctors
appointment. Physical examination reveals a tuft of hair on her lower back,
ultrasound shows no herniation of any kind. Which of the following conditions
does this baby have?
(A) Anencephaly
(B) Meningocele
(C) Meningomyelocele
(D) Spina bifida cystic
(E) Spina bifida occulta
33- Patients with renal artery stenosis may present with very high blood
pressures due to increased rennin secretion. Which of the following structures
in the kidney is responsible for sensing inadequate perfusion and secreting
rennin?
(A) Afferent arteriole
(B) Collecting duct
(C) Distal convoluted tubule
(D) Efferent arteriole
(E) Loop of Henle
34- A 48-year-old man is hospitalized for shock after massive blood loss in a
motor vehicle accident. On the patient second day in the hospital, his blood
urea nitrogen(BUN) and creatinine level begins to rise and he develops pitting
edema to his knees. A subsequent Urinalysis shows numerous granular casts.
Which of the following is the most appropriate treatment?
(A) Angioplasty
(B) Broad-spectrum antibiotics
(C) Corticosteroids
(D) Fluids and analysis
(E) Use of ultrasound to remove blockage
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(B) Appendicitis
(C) Ectopic pregnancy
(D) Localized cystitis
(E) Premature labor
(F) Pyelonephritis
37- A 59-year-old woman with type 2 diabetes mellitus comes to her primary
care physician for a routine visit. Her creatinine level has been slowly
increasing over the last decade due to the poor compliance with her medial
regimen. If her renal disease were to progress she would be at risk for
developing which of the conditions?
(A) Bacteriuria
(B) Hypokalemia
(C) Hypotension
(D) Metabolic alkalosis
(E) Osteomalacia
(F) Polycythemia
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39- A 53-year-old woman experiences hot flashes associated with menopause.
She calls her primary care physician to ask for advice about the risks and
benefits of hormone replacement therapy (HRT). Which of the following is a
potential benefit of HRT?
(A) Decreased risk of breast cancer
(B) Decreased risk of deep venous thrombosis
(C) Decreased risk of hip fracture
(D) Decreased risk of myocardial infarction
(E) Decreased risk of stroke
40- A 50-year-old man is treated for septic shock with multiple antibiotics. Seven
days later The patient is alert and oriented, and his tissue perfusion has
returned to normal. However, he describes a terrible feeling that the world
is spinning. Which of the following therapeutic agents is most likely
responsible for this patients symptoms?
(A) Erythromycin
(B) Gentamicin
(C) Imipenem
(D) Metronidazole
(E) Piperacillin-tazobactam
41-During dental procedures, it is possible small fragments may be aspirated into the
trachea and cause aspiration pneumonia. If the patient is sitting upright during the
procedure, which of the following is the most common site of aspiration
pneumonia?
(A) Left lower lobe
(B) Left upper lobe
(C) Lingula
(D) Right lower lobe
(E) Right upper lobe
42- While examining a patient, the physician notices decreased breath sounds at the
right lower lobe, dullness on percussion, and decreased tactile fremitus without
tracheal deviation. These findings most likely represent which of the following?
(A) Bronchial obstruction
(B) Intestinal infiltration
(C) Lobar pneumonia
(D) Pleural effusion
(E) Pneumothorax
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43- A 10-year-old boy is brought to the emergency department after becoming
less responsive following several bouts of nausea and vomiting. The patient is
tachycardic and is breathing deeply and slowly. Laboratory studies are
remarkable for a serum pH of 7.21, a serum glucose level of 700 mg/dL, a
serum bicarbonate level of 16mEq/L and a serum anion gap of 22(normal 7-
16). Intravenous fluids and insulin are administrated. Measurement and
management of which of the following electrolytes are most critical in this
patient?
(A) Bicarbonate
(B) Calcium
(C) Chloride
(D) Potassium
(E) Sodium
45- A 36-year-old man who completed a marathon 6 hours earlier presents to the
emergency department with severe muscle pain and swelling and complaints
of red urine. Laboratory tests show a creatine kinase level of 6800 U/L, but on
RBCs on urinalysis. Which of the following symptoms would most likely also
be present?
(A) Arrhythmia
(B) Hepatomegaly
(C) Inflammation of the metacarpophalangeal joints
(D) Pain in a dermatomal distribution
(E) Shuffling gait
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46- If either the ulnar or the radial arteries are occluded , which arteries ensure
adequate collateral arterial flow in the hand?
(A) Anterior and posterior interosseous
(B) Arcuate
(C) Common and proper palmar digitals
(D) Deep and superficial dorsalis pedis
(E) Deep and superficial palmar arch
50- All the following structures have attachment to the medial femoral condyle
EXCEPT the
(A) Adductor magnus
(B) Gastrocnemius medial head
(C) Popliteus
(D) Superficial medial collateral ligament
(E) Patellofemoral ligament
51- Which of the following muscles have their origin on the scapula and across
the elbow?
(A) Coracobrachialis and biceps
(B) Coracobrachialis and brachialis
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(C) Brachialis and biceps
(D) Biceps and triceps
(E) Brachialis and triceps
58- Which of the following graft types has both osteoinductive and
osteoconductive properties:
(A) Autogenous bone marrow
(B) Coral-based hydroxyapatite bone graft substitute
(C) Bone morphogenetic protein -2 (BMP-2)
(D) Recombinant bone morphogenetic protein-7 (rhBMP-7)
(E) Cancellous bone graft
59- Which of the following defines osteoporosis according to the world health
organization:
(A) 0.5 to 1.0 standard deviation(SD) below aged-matched controls
(B) 1.0 to 2.0 SD below age-matched controls
(C) 1.0 to 2.5 SD below age-matched controls
(D) More than 2.5 SD below age-matched controls
(E) 2.5 to 5.0 SD below age-matched controls
60- The Achilles tendon reflex (ankle reflex) is transmitted through which of the
following nerve root:
(A) L4
(B) L5
(C) S1
(D) S2
(E) S3
61- A 10-year-old child injures his elbow and presents with swelling and
limitations of voluntary movement. The radiographs show no obvious
fracture, but it does show a Baumann angle of 71 and an even elevation of the
posterior fat pad. You tell the parents That this most likely represents:
(A) A congenital anomaly with a valgus deformity of the elbow
(B) A medial epicondyle fracture
(C) A Salter l physeal separation
(D) An occult supracondylar fracture
(E) A variation of norma
62- Adult articular cartilage receives its nutrition through which of the following
mechanisms
(A) Fine capillary network from the synovial tissues
(B) Fine capillary network through the subchondral bone
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(C) Fine capillary network from the perichondral ring
(D) Diffusion from the synovial fluid through large pores
(E) Diffusion from the synovial fluid through small pores
64- Perianal sensation is derived from which of the following nerve roots:
(A) L2, L3 and L4
(B) L3, L4,and L5
(C) L5, S1 and S2
(D) S1 ,S2 and S3
(E) S2, S3, S4, and S5
65- The skin of the anterior middle third of the thigh is innervated by which of
the following sensory segmental levels:
(A) T12
(B) L1
(C) L2
(D) L3
(E) L4
66- Which of the following levels of the spinal cord principally innervates the
main flexor of the hip:
(A) T10, T11 and T12
(B) L1, L2, and L3
(C) L2, L3 and L4
(D) L4, L5 and S1
(E) L5, S1 and S2
67- During a fracture repair systemic as well as local factors come into play.
Which of the following is considered a systemic factor in fracture healing:
(A) Degree of vascular injury
(B) Degree of bone loss
(C) Age
(D) Type of bone affected
(E) Degree of immobilization
68- Which of the following bone tumors commonly occurs in patients with closed
physes between 20 and 50 years of age:
(A) Osteoid osteoma
(B) Chondromyxiod fibroma
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(C) Solitary bone cyst
(D) Giant cell tumor
(E) Non-ossifying fibroma
70- The most important aspect of treatment in the earliest stages of Legg-Calve-
Perthes Disease is:
(A) Frequent observation
(B) Administration of anti-inflammatory medication
(C) Restoration of motion of the hip
(D) Containment of the femoral head within the acetabulum
(E) Aspiration of the hip
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72- Non union is more common in:
(A) Fracture lateral condyle of humerus
(B) Supracondylar fracture of humerus
(C) Colles fracture
(D) Fracture of olecranon
(E) Fracture surgical neck of humerus
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79- Most common complication of fracture shaft of femur is:
(A) Malunion
(B) Nonunion
(C) Knee stiffness
(D) Fat embolism
94- Solitary bone cyst is characterized by the following features EXCEPT that it:
(A) Occurs most often in children and adolescent
(B) Usually arises in the diaphysis of a long bone
(C) Often remains symptomless until complicated by pathological fracture
(D) Appears as clear ovoid expanding cavity in the x-ray
(E) May be associated with new bone formation
97- Septic arthritis of infancy usually affects which of the following joints:
(A) Shoulder
(B) Elbow
(C) Wrist
(D) Hip
(E) Knee
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98- In children,the treatment of tuberculosis of the hip includes the following
EXCEPT;
(A) Tuberculostatic drugs
(B) Weight traction to correct deformity
(C) Fixation of the joint in the position of function
(D) Aspiration of cold abscess
(E) Extra-articular arthro
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