CSIR-UGC-JRF-NET Life Sciences-Notes (Syllabus wise)

Biomolecules (Carbohydrates, Lipids, Proteins, Nucleic acids and Vitamins).

Stabilizing interactions
pH, buffer, molarity, normality
Membrane structure and function
Operon
Cell organelles
Cell division, checkpoints, cyclins involved and cell cycle
Cellular communications: Tight junction, Gap Junctions ..
DNA replication enzymes involved
Transcription- translation Enzymes involved
Inhibitors, mode of action of antibiotics
Post- translational modification of proteins
Cell signalling: Hormones and their receptors, cell surface receptor, signalling
through G- protein coupled receptors.
Oncology: Mode of action of tumor suppressor genes like p53, rB etc
Anticancer drugs source & mode of action example: tamoxifen is an estrogen
receptor blocker, Methotrexate
Specific immune cells affected by diseases eg: HIV virus attacks T helper cells,
Mycobacterium tuberculosis attacks macrophages
Different types of immunoglobulins and its importance
MHCs
Autoimmune disorders
Cell signalling: Hormones and their receptors, cell surface receptor, signalling
through G- protein coupled receptors.
Photosynthesis - C3 , C4 and CAM pathways.
Respiration
Nitrogen metabolism
Plant hormones :Precursors and functions
Phytochromes, Secondary metabolites synthesis, pathways
Flowering genes in plants
Mendelian ratio + statistics.
Extra chromosomal inheritance: Inheritance of Mitochondrial and chloroplast genes,
maternal inheritance.
Microbial genetics: transformation, conjugation, transduction especially Hfr
prophage.
Cot curve analysis
Human genetics : Pedigree analysis, genetic disorders. (Genetics Problems)
ABO blood group
Structural and numerical alterations of chromosomes : Deletion, duplication,
inversion, translocation, ploidy and their genetic implications.
Mitotic and meiotic Non-disjunction

Darwinisms; The evolutionary synthesis.

Origin of cells and unicellular evolution: endosymbiotic theory. Concept of Oparin and
Haldane; Experiment of Miller (1953);
 Rules In ecology (Allens rule, Bergmans rule, Glogers rule, Yodas Law)
Geological time scale (make some codes in order to remember).
Gene pool, Gene frequency; Hardy-Weinberg Law; concepts and rate of change in
gene frequency through natural selection. (Genetics Problems)
Speciation, allpatry and sympatry, convergent, divergent and parallel evolution.
Major Biomes of the World
Biosphere Reserve and Sanctuaries
Endangered: plants, animals and birds (In India)
Techniques in molecular biology and its applications
Microscopic Techniques