muahahah V. Mezenterica superioara/inferioara si V. Splenica se unesc pt a forma V. Porta.

Aceasta
intra prin hilul hepatic unde prin mai multe ramificatii se varsa in Capilarele Sinusoidale (unde se
amesteca cu sangele arterial) apoi in Vena Centrolobulara. Acestea din urma vor forma V. Hepatice
ce se varsa in V. Cava Inferioar
The liver has the capacity to convert important hormones
and vitamins into a more active form. Examples include the
initial hydroxylation of vitamin D and the deiodination of
the thyroid hormone thyroxine (T4) to triiodothyronine
(T3). Moreover, numerous enzymes in the liver process lipophilic
chemicals into more polar, water-soluble metabolites,
which are more readily excreted into bile.
Bile is a complex secretory product produced by the liver.
Biliary secretion has two principal functions: (1) elimination
of many endogenous and exogenous waste products from
the body, such as bilirubin and cholesterol; and (2) promotion
of digestion and absorption of lipids from the intestine.

The composition of bile is modifi ed signifi cantly as a resultof the absorptive and secretory properties of
epithelial cells
that line the intrahepatic and extrahepatic bile ducts. Moreover,
bile solutes are further concentrated as bile is stored in
the gallbladder.

Hepatocytes are secretory epithelial cells

that separate the lumen of the bile canaliculi
from the fenestrated endothelium of
the vascular sinusoids

Hepatocytes can be thought of as being

arranged as classic hepatic lobules, portal
lobules, or acinar units
The complex structure of the liver makes it diffi cult to defi ne
a single unitsomething analogous to the nephron in the
kidneythat is capable of performing the functions of the
entire liver. One way of viewing the organization of the liver
is depicted in Figures 46-1 and 46-2, in which we regard the
central vein as the core of the classic hepatic lobule. Thus,
the classic hepatic lobule (Fig. 46-3A) includes all hepatocytes
drained by a single central vein, and it is bounded by
two or more portal triads. Alternatively, we can view the liver
as though the triad is the core of a portal lobule (Fig. 46-3B).
Thus, the portal lobule includes all hepatocytes drained by
a single bile ductule and is bounded by two or more central
veins. A third way of viewing the liver is to group the hepatocytes
according to their supply of arterial blood (Fig. 46-
3C). Thus, the portal acinus is a small, three-dimensional
mass of hepatocytes that are irregular in size and shape, with
one axis formed by a line between two triads (i.e., high PO2)
and another axis formed by a line between two central veins

Bile drains from its site of secretion

in the canaliculi into small terminal
ductules, then into progressively larger
ducts of the biliary tree, and eventually
into the duodenum through a single
large common duct