Forgram® [vial]

MIMS Class : Cephalosporins 

Contents Ceftriaxone Na
Treatment of infections of the lower resp tract, acute
bacterial otitis media, skin & skin structure infection, UTI,
Indications uncomplicated gonorrhea, pelvic inflammatory disease,
bacterial septicemia, bone & joint infections, intra-abdominal
infections, meningitis.
IM/IV Adult 1-2 g once daily. Max: 4 g daily. Lower resp tract
infection 1g IV 12 or 24 hrly. Uncomplicated gonorrhea 250 mg IM
as a single dose. Pelvic inflammatory disease 250 mg IM as a
single dose. Surgical prophylaxis 1 g IV as a single dose within 2
hr surgery. Orthopedic surgery 2 g IV as a single dose 2 hr pre-
Dosage op. Meningitis 2 g IV 12 hrly. Infant & childn ≤12 yr Mild to
moderate infection 50-75 mg/kg body wt once daily. Max: 2 g
daily. Severe infection 100 mg/kg body wt once daily. Max: 4 g
daily. Duration of therapy: 4-14 days. Acuteotitis media 50 mg/kg
body wt IM or IV as a single dose. Max: 1 g. Hepatic &renal
impairment Max: 2 g daily.
Hypersensitivity to cephalosporins and penicillins. Hypersensitivity
to lidocaine soln (in case of IM inj). Hyperbilirubinemic neonates
Contraindications
esp prematures. Concurrent administration with calcium-
containing solutions or products in newborns.
Special History of colitis. Hepatic & renal impairment. Monitor prothrombin
Precautions time. Pregnancy & lactation.
Pain, induration, ecchymosis, tenderness at inj site; rash;
Adverse Drug eosinophilia, thrombocytosis, leukopenia; diarrhea; elevated AST,
Reactions ALT & BUN.
View ADR Monitoring Website
Probenecid, aminoglycosides, trovafloxacin, alcohol.
Drug Interactions
View more drug interactions with Forgram

Plendil ER® [tab]
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MIMS Class : Anti-Anginal Drugs, Calcium Antagonists  
Contents Felodipine
Indications All grades of HTN. Angina pectoris.
Dosage HTN Initially 5 mg once daily. Maintenance 5-10 mg once
daily. Elderly Initial: 2.5 mg daily. Angina pectoris Initially 5 mg
once daily increasing to 10 mg once daily if needed. Severely
impaired liver function Lower dose. Dose titration: 2.5 mg.
Overdosage View Plendil ER overdosage for action to be taken in the event of
an overdose.
Administration May be taken with or without food (Take without food or following
a light meal not rich in fat or carbo. Swallow whole, do not
chew/crush.).
Contraindications Pregnancy, uncompensated heart failure, acute MI, unstable
angina pectoris.
Special
Precautions click to view

Adverse Drug Flushing, headache, palpitations, dizziness, fatigue, peripheral

Reactions oedema.
View ADR Monitoring Website
Drug Interactions Cimetidine, erythromycin, itraconazole, ketoconazole, certain
flavonoids in grapefruit juice. Phenytoin, carbamazepine,
barbiturates, rifampicin, tacrolimus.
View more drug interactions with Plendil ER
Pregnancy Category C: Either studies in animals have revealed adverse
Category (US effects on the foetus (teratogenic or embryocidal or other) and
FDA) there are no controlled studies in women or studies in women
and animals are not available. Drugs should be given only if the
potential benefit justifies the potential risk to the foetus.
Storage View Plendil ER storage conditions for details to ensure optimal
shelf-life.
Mechanism of View Plendil ER mechanism of action for pharmacodynamics and
Action pharmacokinetics details.
MIMS Class Anti-Anginal Drugs / Calcium Antagonists
ATC C08CA02 - Felodipine ; Belongs to the class of dihydropyridine
Classification

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 derivative selective calcium-channel blockers with mainly
vascular effects. Used in the treatment of cardiovascular
diseases.

Betaloc® [tab]
MIMS Class : Beta-Blockers 

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Contents Metoprolol tartrate
Indications Listed in Dosage.
Dosage HTN, angina pectoris, cardiac arrhythmias 100-200 mg daily, as a
single dose in the morning or in divided doses (morning &
evening). Maintenance: 100-200 mg daily. Can be combined w/
other antihypertensives. Post-MIMaintenance: 200 mg daily in
divided doses (morning & evening). Functional heart disorder w/
palpitation 100 mg once daily in the morning, increased to 200
mg. Migraine prophylaxis 100-200 mg daily in divided doses
(morning & evening). Hyperthyroidism 150-200 mg daily in 3-4
doses.
Overdosage View Betaloc overdosage for action to be taken in the event of an
overdose.
Administration Should be taken on an empty stomach
Contraindications AV block II or III, unstable decompensated cardiac failure,
cardiogenic shock, marked sinus bradycardia, sick-sinus
syndrome, peripheral arterial circulatory disorder. Suspected
acute MI w/ heart rate <45 beats/min, P-Q interval >0.24 sec or
systolic BP <100 mmHg.
Special Asthma, AV conduction disorder & pheochromocytoma.
Precautions Treatment should be w/drawn gradually. For patients undergoing
elective surgery, employ a β-blocker as premed. Cardiac
decompensation. May impair ability to drive or operate machinery.
Pregnancy & lactation.
Adverse Drug Bradycardia, postural disorders, cold hands & feet, palpitation,
Reactions fatigue, dizziness, headache, dyspnea. Nausea, abdominal pain,
diarrhea & constipation.
View ADR Monitoring Website
Drug Interactions IV Ca-antagonist of verapamil & diltiazem type. Class I
antiarrhythmics. Antihistamines, H2-blockers, antidepressants,
antipsychotics. Sympathomimetic ganglion-blocking agent, other
β-blockers, MAOIs, clonidine, inhalation
anesth, rifampicin, alcohol, hydralazine. Indomethacin & other
prostaglandin synthetase inhibitor. Oral antidiabetics. Digitalis
glycosides. COX-2 inhibitors.

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 View more drug interactions with Betaloc
Pregnancy
Category (US
FDA) Category C: Either studies in animals have revealed adverse
effects on the foetus (teratogenic or embryocidal or other) and
there are no controlled studies in women or studies in women and
animals are not available. Drugs should be given only if the
potential benefit justifies the potential risk to the foetus.
in 2nd & 3rd trimesters.

Category D: There is positive evidence of human foetal risk, but

the benefits from use in pregnant women may be acceptable
despite the risk (e.g., if the drug is needed in a life-threatening
situation or for a serious disease for which safer drugs cannot
be used or are ineffective).
Storage View Betaloc storage conditions for details to ensure optimal
shelf-life.
Mechanism of View Betaloc mechanism of action for pharmacodynamics and
Action pharmacokinetics details.
MIMS Class Beta-Blockers
ATC C07AB02 - Metoprolol ; Belongs to the class of selective beta-
Classification blocking agents. Used in the treatment of cardiovascular
diseases.

Blopress® [tab]
MIMS Class : Angiotensin II Antagonists 
Contents Candesartan cilexetil

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Indications Hypertension.
Dosage Adult 8 or 16 mg once daily.
Overdosage View Blopress overdosage for action to be taken in the event of
an overdose.
Administration May be taken with or without food
Contraindications Pregnancy. Severe or end-stage renal impairment. Childn.
Special Renal artery stenosis, severe intravascular vol depletion.
Precautions Lactation. May affect ability to drive or operate machinery.
Adverse Drug Headache, upper resp tract infection, back pain, dizziness,
Reactions nausea.
View ADR Monitoring Website
Drug Interactions K-sparing diuretics, K supplements, diuretics, lithium, angiotensin
converting enzyme, β-blockers, NSAIDs,indomethacin.
View more drug interactions with Blopress
Pregnancy
Category (US
FDA) Category C: Either studies in animals have revealed adverse
effects on the foetus (teratogenic or embryocidal or other) and
there are no controlled studies in women or studies in women and
animals are not available. Drugs should be given only if the
potential benefit justifies the potential risk to the foetus.
in 2nd & 3rd trimesters.

Category D: There is positive evidence of human foetal risk, but

the benefits from use in pregnant women may be acceptable
despite the risk (e.g., if the drug is needed in a life-threatening
situation or for a serious disease for which safer drugs cannot
be used or are ineffective).
Storage View Blopress storage conditions for details to ensure optimal
shelf-life.
Mechanism of View Blopress mechanism of action for pharmacodynamics and
Action pharmacokinetics details.
MIMS Class Angiotensin II Antagonists

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ATC C09CA06 - Candesartan ; Belongs to the class of angiotensin II
Classification antagonists. Used in the treatment of cardiovascular disease.

Pritor® [tab]
MIMS Class : Angiotensin II Antagonists 
Contents Telmisartan

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Indications Treatment of essential HTN.
Dosage 20-40 mg once daily. Max: 80 mg once daily. Severe
HTN Monotherapy: 160 mg daily. Combination w/
hydrochlorothiazide: 12.5-25 mg daily. Hepatic impairmentMax: 40
mg once daily.
Overdosage View Pritor overdosage for action to be taken in the event of an
overdose.
Administration May be taken with or without food
Contraindications 2nd-3rd trimester of pregnancy, lactation. Biliary obstructive
disorders. Severe hepatic or renal impairment. Fructose
intolerance.
Special Renovascular HTN, renal & hepatic impairment & kidney
Precautions transplant, intravascular vol depletion, other conditions w/
stimulation of the renin-angiotensin-aldosterone system, primary
aldosteronism, aortic & mitral valve stenosis, obstructive
hypertrophic cardiomyopathy, hyperkalemi. Monitor serum lithium
level.
Adverse Drug UTI, upper resp tract infections, anxiety, insomnia, depression,
Reactions visual disturbance, vertigo, GI disorders, eczema, athralgia, back
pain, leg cramps/pain, myalgia, tendinitis like symptoms, chest
pain, influenza-like symptoms. Dyspnea, anemia,
thrombocytopenia, eosinophilia. Bradycardia, tachycardia,
hypotension, orthostatic hypotension.
View ADR Monitoring Website
Drug Interactions Digoxin, warfarin, hydrochlorthiazide, glibenclamide, ibuprofen,
paracetamol & amlodipine. Lithium.
View more drug interactions with Pritor
Pregnancy
Category (US
FDA) Category C: Either studies in animals have revealed adverse
effects on the foetus (teratogenic or embryocidal or other) and
there are no controlled studies in women or studies in women and
animals are not available. Drugs should be given only if the
potential benefit justifies the potential risk to the foetus.
in 2nd & 3rd trimesters.

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 Category D: There is positive evidence of human foetal risk, but
the benefits from use in pregnant women may be acceptable
despite the risk (e.g., if the drug is needed in a life-threatening
situation or for a serious disease for which safer drugs cannot
be used or are ineffective).
Storage View Pritor storage conditions for details to ensure optimal shelf-
life.
Description View Pritor description for details of the chemical structure and
excipients (inactive components).
Mechanism of View Pritor mechanism of action for pharmacodynamics and
Action pharmacokinetics details.
MIMS Class Angiotensin II Antagonists
ATC C09CA07 - Telmisartan ; Belongs to the class of angiotensin II
Classification antagonists. Used in the treatment of cardiovascular disease.

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